ProQR Therapeutics N.V.
PRQR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001612940
In the last 90 days, ProQR Therapeutics N.V. insiders filed 4 open-market purchases and 0 sales; 70 institutions reported holding it in 13F filings for Q2 2026, worth $113.0M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in ProQR Therapeutics N.V. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 65
- +2 vs. Q3 2025
- Shares held
- 37.2M
- −334.9K (−0.9%) vs. Q3 2025
- Total value
- $75.1M
- −$4.80M (−6.0%) vs. Q3 2025
- New holders
- 10
- 23 more added
- Sold out
- 8
- 10 more reduced
1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRQR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 70 | $113.0M |
| Q1 2026 | 69 | $56.8M |
| Q4 2025 | 65 | $75.1M |
| Q3 2025 | 64 | $80.0M |
| Q2 2025 | 62 | $82.4M |
| Q1 2025 | 65 | $54.9M |
| Q4 2024 | 77 | $117.7M |
| Q3 2024 | 47 | $31.7M |
| Q2 2024 | 48 | $28.6M |
| Q1 2024 | 49 | $39.8M |
| Q4 2023 | 47 | $37.0M |
| Q3 2023 | 46 | $24.3M |
| Q2 2023 | 51 | $34.2M |
| Q1 2023 | 55 | $47.5M |
| Q4 2022 | 46 | $60.0M |
| Q3 2022 | 47 | $15.9M |
| Q2 2022 | 51 | $17.2M |
| Q1 2022 | 58 | $28.7M |
| Q4 2021 | 74 | $364.8M |
| Q3 2021 | 67 | $333.4M |
| Q2 2021 | 63 | $259.4M |
| Q1 2021 | 64 | $286.4M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding ProQR Therapeutics N.V.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Medallion Wealth Advisors, LLC | 10 | $20 | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 34 | $69 | 0.00% | 00.0% | Unchanged |
| TD Waterhouse Canada Inc. | 40 | $80 | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 283 | $572 | 0.00% | −185−39.5% | Reduced |
| SBI Securities Co., Ltd. | 515 | $1.04K | 0.00% | −37−6.7% | Reduced |
| PFS Partners, LLC | 1,000 | $2.02K | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 1,000 | $2.02K | 0.00% | +1,000 | New |
| Tower Research Capital LLC (TRC) | 1,211 | $2.45K | 0.00% | +318+35.6% | Added |
| Steward Partners Investment Advisory, LLC | 1,300 | $2.63K | 0.00% | 00.0% | Unchanged |
| BlackRock, Inc. | 3,945 | $7.97K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 4,000 | $8.08K | 0.00% | −1,610−28.7% | Reduced |
| Royal Bank of Canada | 10,303 | $20.0K | 0.00% | −81,904−88.8% | Reduced |
| Truist Financial Corp | 10,000 | $20.2K | 0.00% | 00.0% | Unchanged |
| ADAR1 Capital Management, LLC | 10,000 | $20.2K | 0.00% | 00.0% | Unchanged |
| Nano Cap New Millennium Growth Fund L P | 10,000 | $20.2K | 0.02% | +10,000 | New |
| Atom Investors LP | 13,107 | $26.5K | 0.00% | 00.0% | Unchanged |
| Guggenheim Capital LLC | 17,224 | $34.8K | 0.00% | +17,224 | New |
| Mariner, LLC | 19,219 | $38.8K | 0.00% | 00.0% | Unchanged |
| Keating Financial Advisory Services, Inc. | 20,000 | $40.4K | 0.01% | +20,000 | New |
| The PNC Financial Services Group, Inc. | 20,097 | $40.6K | 0.00% | +570+2.9% | Added |
| JustInvest LLC | 22,314 | $45.1K | 0.00% | 00.0% | Unchanged |
| Moody Lynn & Lieberson, LLC | 25,000 | $50.5K | 0.00% | +25,000 | New |
| Invesco Ltd. | 25,347 | $51.2K | 0.00% | +25,347 | New |
| Fifth Third Bancorp | 30,000 | $60.6K | 0.00% | 00.0% | Unchanged |
| RFG Advisory, LLC | 30,000 | $60.6K | 0.00% | 00.0% | Unchanged |
| Group One Trading, L.P. | 30,388 | $61.4K | 0.00% | +30,388 | New |
| Simplex Trading, LLC | 44,269 | $89.4K | 0.00% | +44,269 | New |
| Velan Capital Investment Management LP | 45,000 | $90.9K | 0.05% | 00.0% | Unchanged |
| Persistent Asset Partners Ltd | 45,154 | $91.2K | 0.04% | +8,874+24.5% | Added |
| Lynx1 Capital Management LP | 68,486 | $138.3K | 0.03% | +68,486 | New |
| Geode Capital Management, LLC | 84,909 | $171.5K | 0.00% | +36,087+73.9% | Added |
| Resources Investment Advisors, LLC. | 85,000 | $171.7K | 0.00% | +5,000+6.3% | Added |
| Quadrature Capital Ltd | 104,231 | $210.5K | 0.00% | +68,091+188.4% | Added |
| Deutsche Bank AG | 108,762 | $219.7K | 0.00% | 00.0% | Unchanged |
| XTX Topco Ltd | 117,900 | $238.2K | 0.01% | +107,713+1,057.4% | Added |
| Franklin Street Advisors Inc | 150,000 | $303.0K | 0.02% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 157,149 | $317.4K | 0.00% | +17,555+12.6% | Added |
| Jane Street Group, LLC | 160,175 | $323.6K | 0.00% | +149,414+1,388.5% | Added |
| Diadema Partners LP | 167,532 | $338.4K | 0.20% | +9,838+6.2% | Added |
| Bank of America Corp | 173,924 | $351.3K | 0.00% | +54,726+45.9% | Added |
| Palo Alto Investors LP | 188,807 | $381.4K | 0.05% | 00.0% | Unchanged |
| Northern Trust Corp | 294,742 | $595.4K | 0.00% | 00.0% | Unchanged |
| Raymond James Financial Inc | 342,886 | $692.6K | 0.00% | +232,616+211.0% | Added |
| Boothbay Fund Management, LLC | 355,283 | $717.7K | 0.02% | +106,993+43.1% | Added |
| Monaco Asset Management SAM | 428,803 | $866.2K | 0.26% | −31,197−6.8% | Reduced |
| Millennium Management LLC | 434,991 | $878.7K | 0.00% | +194,369+80.8% | Added |
| Two Sigma Advisers, LP | 452,400 | $913.8K | 0.00% | +223,800+97.9% | Added |
| Citadel Advisors LLC | 583,222 | $1.18M | 0.00% | −73,790−11.2% | Reduced |
| Walleye Capital LLC | 591,785 | $1.20M | 0.01% | +59,808+11.2% | Added |
| Nomura Asset Management International Inc. | 620,000 | $1.25M | 0.00% | +620,000 | New |
| UBS Group AG | 797,664 | $1.61M | 0.00% | +703,114+743.6% | Added |
| Point72 Asset Management, L.P. | 813,650 | $1.64M | 0.00% | +63,650+8.5% | Added |
| Two Sigma Investments, LP | 839,384 | $1.70M | 0.00% | +422,084+101.1% | Added |
| M28 Capital Management LP | 1,019,498 | $2.06M | 1.50% | 00.0% | Unchanged |
| ArrowMark Colorado Holdings LLC | 1,164,722 | $2.35M | 0.05% | −81,512−6.5% | Reduced |
| Platinum Investment Management Ltd | 1,235,514 | $2.50M | 0.58% | 00.0% | Unchanged |
| Morgan Stanley | 1,367,119 | $2.76M | 0.00% | −1,534,083−52.9% | Reduced |
| Ikarian Capital, LLC | 1,492,229 | $3.01M | 0.39% | +600,000+67.2% | Added |
| Kynam Capital Management, LP | 1,566,317 | $3.16M | 0.21% | −83,145−5.0% | Reduced |
| DAFNA Capital Management LLC | 1,567,561 | $3.17M | 0.74% | 00.0% | Unchanged |
| Sio Capital Management, LLC | 2,164,181 | $4.37M | 0.72% | +89,042+4.3% | Added |
| Affinity Asset Advisors, LLC | 2,454,278 | $4.96M | 0.36% | −1,145,722−31.8% | Reduced |
| Standard Life Aberdeen plc | 2,950,676 | $5.96M | 0.01% | +651,853+28.4% | Added |
| Privium Fund Management B.V. | 5,357,762 | $10.8M | 1.99% | +359,475+7.2% | Added |
| Adage Capital Partners GP, L.L.C. | 6,253,467 | $12.6M | 0.02% | 00.0% | Unchanged |
| Siren, L.L.C. | 0 | $0 | 0.00% | −1,552,183−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −620,000−100.0% | Sold out |
| Woodline Partners LP | 0 | $0 | 0.00% | −92,140−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −25,245−100.0% | Sold out |
| Citigroup Inc | 0 | $0 | 0.00% | −22,724−100.0% | Sold out |
| Kestra Advisory Services, LLC | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Advisor Group Holdings, Inc. | 0 | $0 | 0.00% | −6,000−100.0% | Sold out |
| Activest Wealth Management | 0 | $0 | 0.00% | −100−100.0% | Sold out |
| Cubist Systematic Strategies, LLC | – | – | – | – | Not filed |