Oruka Therapeutics, Inc.
ORKA- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000907654
In the last 90 days, Oruka Therapeutics, Inc. insiders filed 0 open-market purchases and 16 sales; 255 institutions reported holding it in 13F filings for Q2 2026, worth $7.05B in total; Viking Global Investors is the only superinvestor holding it.
13F holders, Q4 2025
Institutional positions in Oruka Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 143
- +38 vs. Q3 2025
- Shares held
- 52.9M
- +7.29M (+16.0%) vs. Q3 2025
- Total value
- $1.60B
- +$726.2M (+82.9%) vs. Q3 2025
- New holders
- 46
- 54 more added
- Sold out
- 8
- 16 more reduced
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ORKA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 255 | $7.05B |
| Q1 2026 | 184 | $2.55B |
| Q4 2025 | 143 | $1.60B |
| Q3 2025 | 105 | $875.8M |
| Q2 2025 | 81 | $386.0M |
| Q1 2025 | 71 | $326.1M |
| Q4 2024 | 66 | $606.6M |
| Q3 2024 | 42 | $604.2M |
| Q2 2024 | 32 | $49.4M |
| Q1 2024 | 23 | $12.7M |
| Q4 2023 | 25 | $12.7M |
| Q3 2023 | 21 | $6.55M |
| Q2 2023 | 23 | $5.75M |
| Q1 2023 | 26 | $5.02M |
| Q4 2022 | 22 | $6.19M |
| Q3 2022 | 25 | $4.58M |
| Q2 2022 | 24 | $4.17M |
| Q1 2022 | 22 | $2.60M |
| Q4 2021 | 21 | $2.41M |
| Q3 2021 | 19 | $4.53M |
| Q2 2021 | 17 | $4.16M |
| Q1 2021 | 17 | $3.20M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Oruka Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 7,261,384 | $220.1M | 0.01% | +3,763+0.1% | Added |
| VR Adviser, LLC | 4,148,428 | $125.7M | 6.21% | 00.0% | Unchanged |
| Fairmount Funds Management LLC | 3,705,262 | $112.3M | 8.55% | 00.0% | Unchanged |
| BlackRock, Inc. | 3,539,415 | $107.3M | 0.00% | +1,334,864+60.6% | Added |
| Viking Global Investors LPSuperinvestorViking Global Investors | 2,666,690 | $80.8M | 0.21% | 00.0% | Unchanged |
| Vanguard Group Inc | 2,453,530 | $74.4M | 0.00% | +676,865+38.1% | Added |
| Deep Track Capital, LP | 2,161,510 | $65.5M | 1.49% | −493,271−18.6% | Reduced |
| RTW Investments, LP | 2,058,148 | $62.4M | 0.62% | +112,499+5.8% | Added |
| Commodore Capital LP | 1,753,054 | $53.1M | 3.54% | 00.0% | Unchanged |
| Paradigm Biocapital Advisors LP | 1,710,316 | $51.8M | 1.39% | +1,710,316 | New |
| Remedium Capital Partners, LLC | 1,552,414 | $47.1M | 27.64% | +1,552,414 | New |
| Perceptive Advisors LLC | 1,476,501 | $44.8M | 0.82% | +208,480+16.4% | Added |
| State Street Corp | 1,383,847 | $41.9M | 0.00% | +731,819+112.2% | Added |
| Avoro Capital Advisors LLC | 1,333,340 | $40.4M | 0.40% | 00.0% | Unchanged |
| Blackstone Group Inc. | 1,165,408 | $35.3M | 0.15% | +315,008+37.0% | Added |
| Polar Capital Holdings Plc | 978,288 | $29.7M | 0.14% | −54,019−5.2% | Reduced |
| Geode Capital Management, LLC | 942,507 | $28.6M | 0.00% | +252,535+36.6% | Added |
| Franklin Resources Inc | 938,421 | $28.4M | 0.01% | −127,361−12.0% | Reduced |
| Affinity Asset Advisors, LLC | 802,342 | $24.3M | 1.75% | −156,838−16.4% | Reduced |
| Mercer Global Advisors Inc | 745,277 | $22.6M | 0.03% | −107,134−12.6% | Reduced |
| Citadel Advisors LLC | 726,118 | $22.0M | 0.01% | +409,232+129.1% | Added |
| Avidity Partners Management LP | 660,424 | $20.0M | 5.77% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 649,346 | $19.7M | 0.00% | +22,540+3.6% | Added |
| Point72 Asset Management, L.P. | 600,000 | $18.2M | 0.03% | −437,002−42.1% | Reduced |
| Woodline Partners LP | 574,553 | $17.4M | 0.07% | +2230.0% | Added |
| Cormorant Asset Management, LP | 533,340 | $16.2M | 0.92% | 00.0% | Unchanged |
| Synergy Financial Management, LLC | 458,946 | $13.9M | 1.45% | +458,946 | New |
| Sr One Capital Management, LP | 430,330 | $13.0M | 1.85% | 00.0% | Unchanged |
| Candriam Luxembourg S.C.A. | 400,509 | $12.1M | 0.06% | +33,515+9.1% | Added |
| Cable Car Capital LLC | 400,000 | $12.1M | 0.75% | −100,000−20.0% | Reduced |
| Charles Schwab Investment Management Inc | 329,496 | $9.99M | 0.00% | +82,570+33.4% | Added |
| Northern Trust Corp | 280,904 | $8.51M | 0.00% | +61,195+27.9% | Added |
| UBS Group AG | 271,013 | $8.21M | 0.00% | +184,453+213.1% | Added |
| Soleus Capital Management, L.P. | 190,000 | $5.76M | 0.24% | +190,000 | New |
| Great Point Partners LLC | 183,330 | $5.56M | 1.80% | 00.0% | Unchanged |
| Barclays PLC | 173,329 | $5.25M | 0.00% | +77,999+81.8% | Added |
| Invesco Ltd. | 143,121 | $4.34M | 0.00% | +126,803+777.1% | Added |
| Bank of America Corp | 139,272 | $4.22M | 0.00% | +60,277+76.3% | Added |
| Longaeva Partners L.P. | 128,110 | $3.88M | 0.46% | +128,110 | New |
| Moody Aldrich Partners LLC | 126,812 | $3.84M | 0.72% | +126,812 | New |
| Morgan Stanley | 122,198 | $3.70M | 0.00% | −12,635−9.4% | Reduced |
| Deutsche Bank AG | 119,329 | $3.62M | 0.00% | +97,210+439.5% | Added |
| Kalehua Capital Management LLC | 118,524 | $3.59M | 3.55% | +118,524 | New |
| Sio Capital Management, LLC | 118,126 | $3.58M | 0.59% | +118,126 | New |
| Bank of New York Mellon Corp | 114,173 | $3.46M | 0.00% | +43,541+61.6% | Added |
| Alyeska Investment Group, L.P. | 100,000 | $3.03M | 0.01% | +100,000 | New |
| Goldman Sachs Group Inc | 92,995 | $2.82M | 0.00% | +73,220+370.3% | Added |
| Nuveen, LLC | 86,347 | $2.62M | 0.00% | +51,034+144.5% | Added |
| Braidwell LP | 84,795 | $2.57M | 0.08% | −1,297,555−93.9% | Reduced |
| Wellington Management Group LLP | 84,716 | $2.57M | 0.00% | −6,378−7.0% | Reduced |
| Secure Asset Management, LLC | 81,664 | $2.48M | 0.39% | +81,664 | New |
| TD Asset Management Inc | 79,896 | $2.42M | 0.00% | +34,020+74.2% | Added |
| D. E. Shaw & Co., Inc. | 76,415 | $2.32M | 0.00% | −19,002−19.9% | Reduced |
| Standard Life Aberdeen plc | 75,680 | $2.29M | 0.00% | 00.0% | Unchanged |
| B Group, Inc. | 75,000 | $2.27M | 1.68% | 00.0% | Unchanged |
| Palo Alto Investors LP | 59,985 | $1.82M | 0.25% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 61,358 | $1.80M | 0.00% | +9,450+18.2% | Added |
| Millennium Management LLC | 58,723 | $1.78M | 0.00% | +58,723 | New |
| American Century Companies Inc | 57,080 | $1.73M | 0.00% | +22,969+67.3% | Added |
| Kennedy Capital Management, Inc. | 48,686 | $1.48M | 0.03% | +420+0.9% | Added |
| Wells Fargo & Company | 43,261 | $1.31M | 0.00% | +22,405+107.4% | Added |
| Swiss National Bank | 43,000 | $1.30M | 0.00% | +43,000 | New |
| Voya Investment Management LLC | 42,503 | $1.29M | 0.00% | +42,503 | New |
| Rhumbline Advisers | 41,017 | $1.24M | 0.00% | +10,690+35.2% | Added |
| Alps Advisors Inc | 39,751 | $1.20M | 0.01% | +39,751 | New |
| Rafferty Asset Management, LLC | 38,485 | $1.17M | 0.00% | +25,698+201.0% | Added |
| Alliancebernstein L.P. | 37,800 | $1.15M | 0.00% | +37,800 | New |
| Verition Fund Management LLC | 35,710 | $1.08M | 0.01% | +35,710 | New |
| Financial Enhancement Group LLC | 31,293 | $1.08M | 0.14% | −1,526−4.6% | Reduced |
| Two Sigma Investments, LP | 28,566 | $865.8K | 0.00% | 00.0% | Unchanged |
| Schroder Investment Management Group | 29,184 | $849.8K | 0.00% | 00.0% | Unchanged |
| Squarepoint Ops LLC | 27,671 | $838.7K | 0.00% | +27,671 | New |
| Voleon Capital Management LP | 23,548 | $713.7K | 0.02% | +23,548 | New |
| State of Wisconsin Investment Board | 22,968 | $696.2K | 0.00% | +22,968 | New |
| California State Teachers Retirement System | 21,658 | $656.5K | 0.00% | +19,960+1,175.5% | Added |
| MetLife Investment Management | 21,362 | $647.5K | 0.00% | +4,849+29.4% | Added |
| ADAR1 Capital Management, LLC | 20,840 | $631.7K | 0.05% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 20,417 | $618.8K | 0.00% | +5,938+41.0% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 20,152 | $608.1K | 0.00% | +7,009+53.3% | Added |
| Hudson Bay Capital Management LP | 20,000 | $606.2K | 0.00% | +20,000 | New |
| Glenmede Trust Co NA | 19,485 | $590.6K | 0.00% | +19,485 | New |
| Legal & General Group Plc | 18,744 | $568.1K | 0.00% | +16,267+656.7% | Added |
| Brookwood Investment Group LLC | 16,569 | $502.2K | 0.06% | +16,569 | New |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | 15,406 | $467.0K | 0.01% | 00.0% | Unchanged |
| Envestnet Asset Management Inc | 15,247 | $462.1K | 0.00% | +15,247 | New |
| Quest Partners LLC | 14,901 | $451.6K | 0.03% | +4,140+38.5% | Added |
| Intech Investment Management LLC | 14,813 | $449.0K | 0.00% | +2,307+18.4% | Added |
| Profund Advisors LLC | 14,623 | $443.2K | 0.01% | +14,623 | New |
| UBS Asset Management Americas Inc | 14,244 | $431.7K | 0.00% | +14,244 | New |
| Resolute Capital Asset Partners LLC | 12,500 | $378.9K | 0.18% | −62,500−83.3% | Reduced |
| Janus Henderson Group PLC | 12,100 | $366.8K | 0.00% | +12,100 | New |
| AlphaCentric Advisors LLC | 10,880 | $329.8K | 0.33% | +10,880 | New |
| Altfest L J & Co Inc | 10,857 | $329.1K | 0.04% | −2,440−18.4% | Reduced |
| Allianz Asset Management GmbH | 10,300 | $312.2K | 0.00% | +10,300 | New |
| Police & Firemen's Retirement System of New Jersey | 10,207 | $309.4K | 0.00% | +2,849+38.7% | Added |
| Citigroup Inc | 9,828 | $297.9K | 0.00% | +6,457+191.5% | Added |
| SEI Investments Co | 9,676 | $293.3K | 0.00% | +9,676 | New |
| Brevan Howard Capital Management LP | 9,416 | $285.4K | 0.01% | +9,416 | New |
| ProShare Advisors LLC | 9,189 | $278.5K | 0.00% | +9,189 | New |
| Virtus Investment Advisers, Inc. | 8,814 | $267.2K | 0.07% | +8,814 | New |