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Oruka Therapeutics, Inc.

ORKA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000907654

In the last 90 days, Oruka Therapeutics, Inc. insiders filed 0 open-market purchases and 14 sales; 255 institutions reported holding it in 13F filings for Q2 2026, worth $7.05B in total; Viking Global Investors is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Oruka Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
143
+38 vs. Q3 2025
Shares held
52.9M
+7.29M (+16.0%) vs. Q3 2025
Total value
$1.60B
+$726.2M (+82.9%) vs. Q3 2025
New holders
46
54 more added
Sold out
8
16 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ORKA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 143 institutions
Q1 2021: 17 institutionsQ2 2021: 17 institutionsQ3 2021: 19 institutionsQ4 2021: 21 institutionsQ1 2022: 22 institutionsQ2 2022: 24 institutionsQ3 2022: 25 institutionsQ4 2022: 22 institutionsQ1 2023: 26 institutionsQ2 2023: 23 institutionsQ3 2023: 21 institutionsQ4 2023: 25 institutionsQ1 2024: 23 institutionsQ2 2024: 32 institutionsQ3 2024: 42 institutionsQ4 2024: 66 institutionsQ1 2025: 71 institutionsQ2 2025: 81 institutionsQ3 2025: 105 institutionsQ4 2025: 143 institutionsQ1 2026: 184 institutionsQ2 2026: 255 institutions
Value heldQ4 2025: $1.60B
Q1 2021: $3.20MQ2 2021: $4.16MQ3 2021: $4.53MQ4 2021: $2.41MQ1 2022: $2.60MQ2 2022: $4.17MQ3 2022: $4.58MQ4 2022: $6.19MQ1 2023: $5.02MQ2 2023: $5.75MQ3 2023: $6.55MQ4 2023: $12.7MQ1 2024: $12.7MQ2 2024: $49.4MQ3 2024: $604.2MQ4 2024: $606.6MQ1 2025: $326.1MQ2 2025: $386.0MQ3 2025: $875.8MQ4 2025: $1.60BQ1 2026: $2.55BQ2 2026: $7.05B
Institutions holding ORKA and their total value by quarter
QuarterHoldersValue
Q2 2026255$7.05B
Q1 2026184$2.55B
Q4 2025143$1.60B
Q3 2025105$875.8M
Q2 202581$386.0M
Q1 202571$326.1M
Q4 202466$606.6M
Q3 202442$604.2M
Q2 202432$49.4M
Q1 202423$12.7M
Q4 202325$12.7M
Q3 202321$6.55M
Q2 202323$5.75M
Q1 202326$5.02M
Q4 202222$6.19M
Q3 202225$4.58M
Q2 202224$4.17M
Q1 202222$2.60M
Q4 202121$2.41M
Q3 202119$4.53M
Q2 202117$4.16M
Q1 202117$3.20M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Oruka Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding ORKA in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Susquehanna International Group, LLP8,665$262.6K0.00%+8,665New
New York State Common Retirement Fund8,600$260.7K0.00%00.0%Unchanged
SG Americas Securities, LLC8,275$251.0K0.00%+8,275New
KLP Kapitalforvaltning AS8,000$242.5K0.00%+8,000New
China Universal Asset Management Co., Ltd.7,888$239.1K0.02%+1,323+20.2%Added
Creative Planning7,696$233.3K0.00%+7,696New
Landscape Capital Management, L.L.C.7,447$225.7K0.02%+7,447New
BNP Paribas Arbitrage, SA5,892$178.6K0.00%+145+2.5%Added
Seven Fleet Capital Management LP5,240$158.8K0.11%+5,240New
Ameritas Investment Partners, Inc.3,132$94.9K0.00%+355+12.8%Added
Russell Investments Group, Ltd.3,041$92.2K0.00%+788+35.0%Added
US Bancorp2,925$88.7K0.00%+2,747+1,543.3%Added
Mirae Asset Global Investments Co., Ltd.2,352$71.3K0.00%+904+62.4%Added
Sterling Capital Management LLC2,224$67.4K0.00%+347+18.5%Added
Caitong International Asset Management Co., Ltd2,214$67.1K0.02%+2,214New
The PNC Financial Services Group, Inc.1,450$44.0K0.00%−564−28.0%Reduced
Amalgamated Bank1,212$37.0K0.00%+283+30.5%Added
Los Angeles Capital Management LLC1,302$36.6K0.00%+1,302New
Royal Bank of Canada1,139$34.0K0.00%+365+47.2%Added
Stone House Investment Management, LLC1,000$30.3K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.950$28.8K0.00%+144+17.9%Added
CWM, LLC586$18.0K0.00%+192+48.7%Added
Balyasny Asset Management LLC536$16.2K0.00%+536New
Tower Research Capital LLC (TRC)495$15.0K0.00%−1,723−77.7%Reduced
DV Trading LLC492$14.9K0.00%+492New
Nisa Investment Advisors, LLC282$8.55K0.00%+282New
Group One Trading, L.P.200$6.06K0.00%+100+100.0%Added
Activest Wealth Management166$5.03K0.00%00.0%Unchanged
J.Safra Asset Management Corp155$4.70K0.00%+131+545.8%Added
Daiwa Securities Group Inc.116$4.00K0.00%00.0%Unchanged
Allworth Financial LP114$3.46K0.00%+109+2,180.0%Added
GAMMA Investing LLC101$3.06K0.00%+101New
Essential Partners LLC27$8180.00%00.0%Unchanged
True Wealth Design, LLC26$7890.00%00.0%Unchanged
Aster Capital Management (DIFC) Ltd25$7580.00%+25New
Cornerstone Financial Management LLC21$6370.00%+21New
Parallel Advisors, LLC20$6060.00%00.0%Unchanged
EverSource Wealth Advisors, LLC16$4850.00%00.0%Unchanged
Larson Financial Group LLC13$3940.00%+2+18.2%Added
Farther Finance Advisors, LLC10$3030.00%00.0%Unchanged
Advisor Group Holdings, Inc.4$1210.00%+3+300.0%Added
IFP Advisors, Inc3$910.00%00.0%Unchanged
CIBC Private Wealth Group, LLC1$300.00%00.0%Unchanged
Jefferies Financial Group Inc.0$00.00%−64,991−100.0%Sold out
Toronto Dominion Bank0$00.00%−58,332−100.0%Sold out
Caption Management, LLC0$00.00%−2,000−100.0%Sold out
Simplex Trading, LLC0$00.00%−729−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−72−100.0%Sold out
Rise Advisors, LLC0$00.00%−36−100.0%Sold out
National Bank of Canada0$00.00%−8−100.0%Sold out
SBI Securities Co., Ltd.0$00.00%−6−100.0%Sold out