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Oruka Therapeutics, Inc.

ORKA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000907654

In the last 90 days, Oruka Therapeutics, Inc. insiders filed 0 open-market purchases and 16 sales; 255 institutions reported holding it in 13F filings for Q2 2026, worth $7.05B in total; Viking Global Investors is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Oruka Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
143
+38 vs. Q3 2025
Shares held
52.9M
+7.29M (+16.0%) vs. Q3 2025
Total value
$1.60B
+$726.2M (+82.9%) vs. Q3 2025
New holders
46
54 more added
Sold out
8
16 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ORKA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 143 institutions
Q1 2021: 17 institutionsQ2 2021: 17 institutionsQ3 2021: 19 institutionsQ4 2021: 21 institutionsQ1 2022: 22 institutionsQ2 2022: 24 institutionsQ3 2022: 25 institutionsQ4 2022: 22 institutionsQ1 2023: 26 institutionsQ2 2023: 23 institutionsQ3 2023: 21 institutionsQ4 2023: 25 institutionsQ1 2024: 23 institutionsQ2 2024: 32 institutionsQ3 2024: 42 institutionsQ4 2024: 66 institutionsQ1 2025: 71 institutionsQ2 2025: 81 institutionsQ3 2025: 105 institutionsQ4 2025: 143 institutionsQ1 2026: 184 institutionsQ2 2026: 255 institutions
Value heldQ4 2025: $1.60B
Q1 2021: $3.20MQ2 2021: $4.16MQ3 2021: $4.53MQ4 2021: $2.41MQ1 2022: $2.60MQ2 2022: $4.17MQ3 2022: $4.58MQ4 2022: $6.19MQ1 2023: $5.02MQ2 2023: $5.75MQ3 2023: $6.55MQ4 2023: $12.7MQ1 2024: $12.7MQ2 2024: $49.4MQ3 2024: $604.2MQ4 2024: $606.6MQ1 2025: $326.1MQ2 2025: $386.0MQ3 2025: $875.8MQ4 2025: $1.60BQ1 2026: $2.55BQ2 2026: $7.05B
Institutions holding ORKA and their total value by quarter
QuarterHoldersValue
Q2 2026255$7.05B
Q1 2026184$2.55B
Q4 2025143$1.60B
Q3 2025105$875.8M
Q2 202581$386.0M
Q1 202571$326.1M
Q4 202466$606.6M
Q3 202442$604.2M
Q2 202432$49.4M
Q1 202423$12.7M
Q4 202325$12.7M
Q3 202321$6.55M
Q2 202323$5.75M
Q1 202326$5.02M
Q4 202222$6.19M
Q3 202225$4.58M
Q2 202224$4.17M
Q1 202222$2.60M
Q4 202121$2.41M
Q3 202119$4.53M
Q2 202117$4.16M
Q1 202117$3.20M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Oruka Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding ORKA in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
CIBC Private Wealth Group, LLC1$300.00%00.0%Unchanged
IFP Advisors, Inc3$910.00%00.0%Unchanged
Advisor Group Holdings, Inc.4$1210.00%+3+300.0%Added
Farther Finance Advisors, LLC10$3030.00%00.0%Unchanged
Larson Financial Group LLC13$3940.00%+2+18.2%Added
EverSource Wealth Advisors, LLC16$4850.00%00.0%Unchanged
Parallel Advisors, LLC20$6060.00%00.0%Unchanged
Cornerstone Financial Management LLC21$6370.00%+21New
Aster Capital Management (DIFC) Ltd25$7580.00%+25New
True Wealth Design, LLC26$7890.00%00.0%Unchanged
Essential Partners LLC27$8180.00%00.0%Unchanged
GAMMA Investing LLC101$3.06K0.00%+101New
Allworth Financial LP114$3.46K0.00%+109+2,180.0%Added
Daiwa Securities Group Inc.116$4.00K0.00%00.0%Unchanged
J.Safra Asset Management Corp155$4.70K0.00%+131+545.8%Added
Activest Wealth Management166$5.03K0.00%00.0%Unchanged
Group One Trading, L.P.200$6.06K0.00%+100+100.0%Added
Nisa Investment Advisors, LLC282$8.55K0.00%+282New
DV Trading LLC492$14.9K0.00%+492New
Tower Research Capital LLC (TRC)495$15.0K0.00%−1,723−77.7%Reduced
Balyasny Asset Management LLC536$16.2K0.00%+536New
CWM, LLC586$18.0K0.00%+192+48.7%Added
GF Fund Management Co. Ltd.950$28.8K0.00%+144+17.9%Added
Stone House Investment Management, LLC1,000$30.3K0.00%00.0%Unchanged
Royal Bank of Canada1,139$34.0K0.00%+365+47.2%Added
Los Angeles Capital Management LLC1,302$36.6K0.00%+1,302New
Amalgamated Bank1,212$37.0K0.00%+283+30.5%Added
The PNC Financial Services Group, Inc.1,450$44.0K0.00%−564−28.0%Reduced
Caitong International Asset Management Co., Ltd2,214$67.1K0.02%+2,214New
Sterling Capital Management LLC2,224$67.4K0.00%+347+18.5%Added
Mirae Asset Global Investments Co., Ltd.2,352$71.3K0.00%+904+62.4%Added
US Bancorp2,925$88.7K0.00%+2,747+1,543.3%Added
Russell Investments Group, Ltd.3,041$92.2K0.00%+788+35.0%Added
Ameritas Investment Partners, Inc.3,132$94.9K0.00%+355+12.8%Added
Seven Fleet Capital Management LP5,240$158.8K0.11%+5,240New
BNP Paribas Arbitrage, SA5,892$178.6K0.00%+145+2.5%Added
Landscape Capital Management, L.L.C.7,447$225.7K0.02%+7,447New
Creative Planning7,696$233.3K0.00%+7,696New
China Universal Asset Management Co., Ltd.7,888$239.1K0.02%+1,323+20.2%Added
KLP Kapitalforvaltning AS8,000$242.5K0.00%+8,000New
SG Americas Securities, LLC8,275$251.0K0.00%+8,275New
New York State Common Retirement Fund8,600$260.7K0.00%00.0%Unchanged
Susquehanna International Group, LLP8,665$262.6K0.00%+8,665New
Virtus Investment Advisers, Inc.8,814$267.2K0.07%+8,814New
ProShare Advisors LLC9,189$278.5K0.00%+9,189New
Brevan Howard Capital Management LP9,416$285.4K0.01%+9,416New
SEI Investments Co9,676$293.3K0.00%+9,676New
Citigroup Inc9,828$297.9K0.00%+6,457+191.5%Added
Police & Firemen's Retirement System of New Jersey10,207$309.4K0.00%+2,849+38.7%Added
Allianz Asset Management GmbH10,300$312.2K0.00%+10,300New
Altfest L J & Co Inc10,857$329.1K0.04%−2,440−18.4%Reduced
AlphaCentric Advisors LLC10,880$329.8K0.33%+10,880New
Janus Henderson Group PLC12,100$366.8K0.00%+12,100New
Resolute Capital Asset Partners LLC12,500$378.9K0.18%−62,500−83.3%Reduced
UBS Asset Management Americas Inc14,244$431.7K0.00%+14,244New
Profund Advisors LLC14,623$443.2K0.01%+14,623New
Intech Investment Management LLC14,813$449.0K0.00%+2,307+18.4%Added
Quest Partners LLC14,901$451.6K0.03%+4,140+38.5%Added
Envestnet Asset Management Inc15,247$462.1K0.00%+15,247New
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management15,406$467.0K0.01%00.0%Unchanged
Brookwood Investment Group LLC16,569$502.2K0.06%+16,569New
Legal & General Group Plc18,744$568.1K0.00%+16,267+656.7%Added
Glenmede Trust Co NA19,485$590.6K0.00%+19,485New
Hudson Bay Capital Management LP20,000$606.2K0.00%+20,000New
Mirae Asset Global ETFs Holdings Ltd.20,152$608.1K0.00%+7,009+53.3%Added
JPMorgan Chase & Co20,417$618.8K0.00%+5,938+41.0%Added
ADAR1 Capital Management, LLC20,840$631.7K0.05%00.0%Unchanged
MetLife Investment Management21,362$647.5K0.00%+4,849+29.4%Added
California State Teachers Retirement System21,658$656.5K0.00%+19,960+1,175.5%Added
State of Wisconsin Investment Board22,968$696.2K0.00%+22,968New
Voleon Capital Management LP23,548$713.7K0.02%+23,548New
Squarepoint Ops LLC27,671$838.7K0.00%+27,671New
Schroder Investment Management Group29,184$849.8K0.00%00.0%Unchanged
Two Sigma Investments, LP28,566$865.8K0.00%00.0%Unchanged
Financial Enhancement Group LLC31,293$1.08M0.14%−1,526−4.6%Reduced
Verition Fund Management LLC35,710$1.08M0.01%+35,710New
Alliancebernstein L.P.37,800$1.15M0.00%+37,800New
Rafferty Asset Management, LLC38,485$1.17M0.00%+25,698+201.0%Added
Alps Advisors Inc39,751$1.20M0.01%+39,751New
Rhumbline Advisers41,017$1.24M0.00%+10,690+35.2%Added
Voya Investment Management LLC42,503$1.29M0.00%+42,503New
Swiss National Bank43,000$1.30M0.00%+43,000New
Wells Fargo & Company43,261$1.31M0.00%+22,405+107.4%Added
Kennedy Capital Management, Inc.48,686$1.48M0.03%+420+0.9%Added
American Century Companies Inc57,080$1.73M0.00%+22,969+67.3%Added
Millennium Management LLC58,723$1.78M0.00%+58,723New
Manufacturers Life Insurance Company, The61,358$1.80M0.00%+9,450+18.2%Added
Palo Alto Investors LP59,985$1.82M0.25%00.0%Unchanged
B Group, Inc.75,000$2.27M1.68%00.0%Unchanged
Standard Life Aberdeen plc75,680$2.29M0.00%00.0%Unchanged
D. E. Shaw & Co., Inc.76,415$2.32M0.00%−19,002−19.9%Reduced
TD Asset Management Inc79,896$2.42M0.00%+34,020+74.2%Added
Secure Asset Management, LLC81,664$2.48M0.39%+81,664New
Wellington Management Group LLP84,716$2.57M0.00%−6,378−7.0%Reduced
Braidwell LP84,795$2.57M0.08%−1,297,555−93.9%Reduced
Nuveen, LLC86,347$2.62M0.00%+51,034+144.5%Added
Goldman Sachs Group Inc92,995$2.82M0.00%+73,220+370.3%Added
Alyeska Investment Group, L.P.100,000$3.03M0.01%+100,000New
Bank of New York Mellon Corp114,173$3.46M0.00%+43,541+61.6%Added
Sio Capital Management, LLC118,126$3.58M0.59%+118,126New