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Oruka Therapeutics, Inc.

ORKA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000907654

In the last 90 days, Oruka Therapeutics, Inc. insiders filed 0 open-market purchases and 16 sales; 255 institutions reported holding it in 13F filings for Q2 2026, worth $7.05B in total; Viking Global Investors is the only superinvestor holding it.

13F holders, Q1 2025

Institutional positions in Oruka Therapeutics, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
71
+6 vs. Q4 2024
Shares held
31.8M
+744.4K (+2.4%) vs. Q4 2024
Total value
$326.1M
−$280.4M (−46.2%) vs. Q4 2024
New holders
16
28 more added
Sold out
10
12 more reduced

1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ORKA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 71 institutions
Q1 2021: 17 institutionsQ2 2021: 17 institutionsQ3 2021: 19 institutionsQ4 2021: 21 institutionsQ1 2022: 22 institutionsQ2 2022: 24 institutionsQ3 2022: 25 institutionsQ4 2022: 22 institutionsQ1 2023: 26 institutionsQ2 2023: 23 institutionsQ3 2023: 21 institutionsQ4 2023: 25 institutionsQ1 2024: 23 institutionsQ2 2024: 32 institutionsQ3 2024: 42 institutionsQ4 2024: 66 institutionsQ1 2025: 71 institutionsQ2 2025: 81 institutionsQ3 2025: 105 institutionsQ4 2025: 143 institutionsQ1 2026: 184 institutionsQ2 2026: 255 institutions
Value heldQ1 2025: $326.1M
Q1 2021: $3.20MQ2 2021: $4.16MQ3 2021: $4.53MQ4 2021: $2.41MQ1 2022: $2.60MQ2 2022: $4.17MQ3 2022: $4.58MQ4 2022: $6.19MQ1 2023: $5.02MQ2 2023: $5.75MQ3 2023: $6.55MQ4 2023: $12.7MQ1 2024: $12.7MQ2 2024: $49.4MQ3 2024: $604.2MQ4 2024: $606.6MQ1 2025: $326.1MQ2 2025: $386.0MQ3 2025: $875.8MQ4 2025: $1.60BQ1 2026: $2.55BQ2 2026: $7.05B
Institutions holding ORKA and their total value by quarter
QuarterHoldersValue
Q2 2026255$7.05B
Q1 2026184$2.55B
Q4 2025143$1.60B
Q3 2025105$875.8M
Q2 202581$386.0M
Q1 202571$326.1M
Q4 202466$606.6M
Q3 202442$604.2M
Q2 202432$49.4M
Q1 202423$12.7M
Q4 202325$12.7M
Q3 202321$6.55M
Q2 202323$5.75M
Q1 202326$5.02M
Q4 202222$6.19M
Q3 202225$4.58M
Q2 202224$4.17M
Q1 202222$2.60M
Q4 202121$2.41M
Q3 202119$4.53M
Q2 202117$4.16M
Q1 202117$3.20M

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Oruka Therapeutics, Inc.; share changes are against Q4 2024.

Institutions holding ORKA in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC5,561,808$57.1M0.00%+49,508+0.9%Added
VR Adviser, LLC4,148,428$42.6M3.62%+862,808+26.3%Added
Fairmount Funds Management LLC3,371,922$34.6M5.37%00.0%Unchanged
RTW Investments, LP1,945,649$20.0M0.31%00.0%Unchanged
Vanguard Group Inc1,637,433$16.8M0.00%+26,782+1.7%Added
Braidwell LP1,572,426$16.1M0.57%+424,750+37.0%Added
Deep Track Capital, LP1,444,709$14.8M0.48%+694,709+92.6%Added
Commodore Capital LP1,419,714$14.6M1.07%00.0%Unchanged
Polar Capital Holdings Plc1,050,000$10.8M0.07%+500,000+90.9%Added
Blackstone Group Inc.783,653$8.04M0.04%+543,479+226.3%Added
BlackRock, Inc.747,674$7.67M0.00%−3,757−0.5%Reduced
Franklin Resources Inc720,547$7.39M0.00%00.0%Unchanged
Frazier Life Sciences Management, L.P.583,327$5.98M0.27%00.0%Unchanged
Affinity Asset Advisors, LLC545,362$5.60M0.88%+176,664+47.9%Added
Morgan Stanley527,791$5.42M0.00%+121,793+30.0%Added
Cable Car Capital LLC450,000$4.62M5.24%+116,629+35.0%Added
Sr One Capital Management, LP430,330$4.42M1.13%00.0%Unchanged
Price T Rowe Associates Inc411,602$4.22M0.00%−915,291−69.0%Reduced
Jefferies Financial Group Inc.405,029$4.16M0.07%+55,000+15.7%Added
Woodline Partners LP390,804$4.01M0.03%−1650.0%Reduced
Redmile Group, LLC386,963$3.97M0.38%−24,765−6.0%Reduced
Geode Capital Management, LLC352,585$3.62M0.00%+10,167+3.0%Added
Avidity Partners Management LP352,124$3.61M0.75%00.0%Unchanged
Susquehanna International Group, LLP350,036$3.59M0.01%+350,036New
Point72 Asset Management, L.P.342,399$3.51M0.01%−18,333−5.1%Reduced
Goldman Sachs Group Inc244,199$2.51M0.00%+244,199New
Ikarian Capital, LLC175,000$1.80M0.58%+175,000New
ADAR1 Capital Management, LLC132,780$1.36M0.26%+132,780New
Candriam Luxembourg S.C.A.116,698$1.20M0.01%+116,698New
Wellington Management Group LLP87,501$897.8K0.00%−7,588−8.0%Reduced
State Street Corp86,681$889.3K0.00%+61,658+246.4%Added
Barclays PLC75,333$772.9K0.00%+750+1.0%Added
Kennedy Capital Management, Inc.65,749$674.6K0.02%+5,255+8.7%Added
Northern Trust Corp59,585$611.3K0.00%−4,459−7.0%Reduced
Toronto Dominion Bank58,332$598.5K0.00%00.0%Unchanged
B Group, Inc.58,215$597.3K0.52%+38,215+191.1%Added
Millennium Management LLC54,126$555.3K0.00%+23,821+78.6%Added
Boothbay Fund Management, LLC53,615$550.1K0.02%+53,615New
Qube Research & Technologies Ltd52,026$533.8K0.00%−100,056−65.8%Reduced
HRT Financial LP46,511$477.0K0.00%+46,511New
TD Asset Management Inc45,876$470.7K0.00%−49,200−51.7%Reduced
Omers Administration Corp44,900$460.7K0.00%+25,100+126.8%Added
Manufacturers Life Insurance Company, The42,919$440.3K0.00%+621+1.5%Added
Weiss Asset Management LP40,000$410.4K0.01%00.0%Unchanged
ExodusPoint Capital Management, LP35,912$368.0K0.00%+35,912New
Renaissance Technologies LLC35,800$367.3K0.00%+35,800New
UBS Group AG33,883$347.6K0.00%+8,721+34.7%Added
Occudo Quantitative Strategies LP24,804$310.1K0.04%+24,804New
Man Group plc29,365$301.3K0.00%+29,365New
Squarepoint Ops LLC22,022$225.9K0.00%+9,847+80.9%Added
Two Sigma Investments, LP21,831$224.0K0.00%+21,831New
Allostery Investments LP20,000$205.2K0.30%00.0%Unchanged
Cannon Global Investment Management, LLC19,000$194.9K0.54%+19,000New
Quest Partners LLC16,335$167.6K0.02%+16,335New
Charles Schwab Investment Management Inc15,608$160.1K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.7,509$77.0K0.01%+88+1.2%Added
Artia Global Partners LP7,380$75.7K0.02%+7,380New
Bank of America Corp4,863$49.9K0.00%+4,665+2,356.1%Added
JPMorgan Chase & Co2,310$23.7K0.00%−490−17.5%Reduced
Group One Trading, L.P.2,108$21.6K0.00%+2,085+9,065.2%Added
Citigroup Inc1,554$15.9K0.00%−6,474−80.6%Reduced
Mirae Asset Global Investments Co., Ltd.1,253$15.7K0.00%+87+7.5%Added
GF Fund Management Co. Ltd.896$9.19K0.00%+161+21.9%Added
Tower Research Capital LLC (TRC)754$7.74K0.00%+170+29.1%Added
BNP Paribas Arbitrage, SA497$5.10K0.00%+29+6.2%Added
Coldstream Capital Management Inc180$1.85K0.00%+180New
Activest Wealth Management166$1.70K0.00%00.0%Unchanged
Daiwa Securities Group Inc.116$1.00K0.00%00.0%Unchanged
Parallel Advisors, LLC20$2050.00%00.0%Unchanged
National Bank of Canada8$820.00%00.0%Unchanged
Royal Bank of Canada10$00.00%−45−81.8%Reduced
Janus Henderson Group PLC0$00.00%−849,410−100.0%Sold out
Perceptive Advisors LLC0$00.00%−845,567−100.0%Sold out
Paradigm Biocapital Advisors LP0$00.00%−819,660−100.0%Sold out
Driehaus Capital Management LLC0$00.00%−308,795−100.0%Sold out
Great Point Partners LLC0$00.00%−228,803−100.0%Sold out
Adage Capital Partners GP, L.L.C.0$00.00%−69,200−100.0%Sold out
683 Capital Management, LLC0$00.00%−33,875−100.0%Sold out
Ensign Peak Advisors, Inc0$00.00%−25,000−100.0%Sold out
Jane Street Group, LLC0$00.00%−17,706−100.0%Sold out
Aster Capital Management (DIFC) Ltd0$00.00%−5−100.0%Sold out
AlphaCentric Advisors LLC––––Not filed