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Oruka Therapeutics, Inc.

ORKA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000907654

In the last 90 days, Oruka Therapeutics, Inc. insiders filed 0 open-market purchases and 16 sales; 255 institutions reported holding it in 13F filings for Q2 2026, worth $7.05B in total; Viking Global Investors is the only superinvestor holding it.

13F holders, Q1 2026

Institutional positions in Oruka Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
184
+43 vs. Q4 2025
Shares held
52.0M
+1.62M (+3.2%) vs. Q4 2025
Total value
$2.55B
+$1.02B (+67.0%) vs. Q4 2025
New holders
63
64 more added
Sold out
20
31 more reduced

2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ORKA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 184 institutions
Q1 2021: 17 institutionsQ2 2021: 17 institutionsQ3 2021: 19 institutionsQ4 2021: 21 institutionsQ1 2022: 22 institutionsQ2 2022: 24 institutionsQ3 2022: 25 institutionsQ4 2022: 22 institutionsQ1 2023: 26 institutionsQ2 2023: 23 institutionsQ3 2023: 21 institutionsQ4 2023: 25 institutionsQ1 2024: 23 institutionsQ2 2024: 32 institutionsQ3 2024: 42 institutionsQ4 2024: 66 institutionsQ1 2025: 71 institutionsQ2 2025: 81 institutionsQ3 2025: 105 institutionsQ4 2025: 143 institutionsQ1 2026: 184 institutionsQ2 2026: 255 institutions
Value heldQ1 2026: $2.55B
Q1 2021: $3.20MQ2 2021: $4.16MQ3 2021: $4.53MQ4 2021: $2.41MQ1 2022: $2.60MQ2 2022: $4.17MQ3 2022: $4.58MQ4 2022: $6.19MQ1 2023: $5.02MQ2 2023: $5.75MQ3 2023: $6.55MQ4 2023: $12.7MQ1 2024: $12.7MQ2 2024: $49.4MQ3 2024: $604.2MQ4 2024: $606.6MQ1 2025: $326.1MQ2 2025: $386.0MQ3 2025: $875.8MQ4 2025: $1.60BQ1 2026: $2.55BQ2 2026: $7.05B
Institutions holding ORKA and their total value by quarter
QuarterHoldersValue
Q2 2026255$7.05B
Q1 2026184$2.55B
Q4 2025143$1.60B
Q3 2025105$875.8M
Q2 202581$386.0M
Q1 202571$326.1M
Q4 202466$606.6M
Q3 202442$604.2M
Q2 202432$49.4M
Q1 202423$12.7M
Q4 202325$12.7M
Q3 202321$6.55M
Q2 202323$5.75M
Q1 202326$5.02M
Q4 202222$6.19M
Q3 202225$4.58M
Q2 202224$4.17M
Q1 202222$2.60M
Q4 202121$2.41M
Q3 202119$4.53M
Q2 202117$4.16M
Q1 202117$3.20M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Oruka Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding ORKA in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC7,431,403$364.5M0.02%+170,019+2.3%Added
VR Adviser, LLC4,148,428$203.5M7.60%00.0%Unchanged
Fairmount Funds Management LLC3,705,262$181.7M13.13%00.0%Unchanged
BlackRock, Inc.3,527,087$173.0M0.00%−12,328−0.3%Reduced
Viking Global Investors LPSuperinvestorViking Global Investors2,666,690$130.8M0.37%00.0%Unchanged
Paradigm Biocapital Advisors LP2,320,316$113.8M2.33%+610,000+35.7%Added
RTW Investments, LP2,058,148$101.0M1.00%00.0%Unchanged
Deep Track Capital, LP2,034,203$99.8M2.06%−127,307−5.9%Reduced
Vanguard Capital Management LLC1,859,631$91.2M0.00%+1,859,631New
State Street Corp1,613,461$79.1M0.00%+229,614+16.6%Added
Remedium Capital Partners, LLC1,565,661$76.8M27.31%+13,247+0.9%Added
Perceptive Advisors LLC1,395,501$68.4M1.35%−81,000−5.5%Reduced
Polar Capital Holdings Plc1,047,693$51.4M0.22%+69,405+7.1%Added
Citadel Advisors LLC1,007,537$49.4M0.04%+281,419+38.8%Added
Franklin Resources Inc1,004,056$49.2M0.01%+65,635+7.0%Added
Geode Capital Management, LLC954,867$46.8M0.00%+12,360+1.3%Added
Mercer Global Advisors Inc802,470$39.4M0.06%+57,193+7.7%Added
Avidity Partners Management LP760,424$37.3M7.55%+100,000+15.1%Added
Price T Rowe Associates Inc727,449$35.7M0.00%+78,103+12.0%Added
Woodline Partners LP574,882$28.2M0.11%+329+0.1%Added
Cormorant Asset Management, LP533,340$26.2M1.32%00.0%Unchanged
Bellevue Group AG507,008$24.9M0.59%+507,008New
Affinity Asset Advisors, LLC499,673$24.5M1.44%−302,669−37.7%Reduced
Synergy Financial Management, LLC476,196$23.4M2.48%+17,250+3.8%Added
Sr One Capital Management, LP430,330$21.1M2.31%00.0%Unchanged
Candriam Luxembourg S.C.A.411,006$20.2M0.10%+10,497+2.6%Added
Vanguard Portfolio Management LLC350,892$17.2M0.00%+350,892New
Charles Schwab Investment Management Inc321,949$15.8M0.00%−7,547−2.3%Reduced
Westfield Capital Management Co LP313,130$15.4M0.06%+313,130New
Northern Trust Corp299,044$14.7M0.00%+18,140+6.5%Added
Vanguard Fiduciary Trust Co257,071$12.6M0.00%+257,071New
Goldman Sachs Group Inc246,711$12.1M0.00%+153,716+165.3%Added
Ikarian Capital, LLC242,021$11.9M1.70%+242,021New
Atika Capital Management LLC229,900$11.3M1.78%+229,900New
UBS Group AG212,271$10.4M0.00%−58,742−21.7%Reduced
Cable Car Capital LLC200,000$9.81M3.39%−200,000−50.0%Reduced
Adage Capital Partners GP, L.L.C.190,030$9.32M0.01%+190,030New
Holocene Advisors, LP185,513$9.10M0.02%+185,513New
Alyeska Investment Group, L.P.184,863$9.07M0.03%+84,863+84.9%Added
Great Point Partners LLC183,330$8.99M2.20%00.0%Unchanged
Jennison Associates LLC176,680$8.67M0.01%+176,680New
Morgan Stanley175,454$8.61M0.00%+53,256+43.6%Added
PFM Health Sciences, LP174,052$8.54M0.90%+174,052New
Silverarc Capital Management, LLC150,908$7.40M0.87%+150,908New
Jones Hill Capital LP140,843$6.91M1.48%+140,843New
Deutsche Bank AG140,789$6.91M0.00%+21,460+18.0%Added
Longaeva Partners L.P.136,884$6.71M0.32%+8,774+6.8%Added
Moody Aldrich Partners LLC135,061$6.62M1.19%+8,249+6.5%Added
Sio Capital Management, LLC132,496$6.50M0.94%+14,370+12.2%Added
Kennedy Capital Management, Inc.126,366$6.20M0.13%+77,680+159.6%Added
Wellington Management Group LLP121,225$5.95M0.00%+36,509+43.1%Added
Kalehua Capital Management LLC118,524$5.81M4.11%00.0%Unchanged
Dimensional Fund Advisors LP113,009$5.54M0.00%+113,009New
Bank of New York Mellon Corp106,883$5.24M0.00%−7,290−6.4%Reduced
ExodusPoint Capital Management, LP101,354$4.97M0.05%+101,354New
Bank of America Corp100,091$4.91M0.00%−39,181−28.1%Reduced
Invesco Ltd.97,042$4.76M0.00%−46,079−32.2%Reduced
Nuveen, LLC86,938$4.26M0.00%+591+0.7%Added
Barclays PLC85,737$4.21M0.00%−87,592−50.5%Reduced
Ensign Peak Advisors, Inc79,380$3.89M0.01%+79,380New
HighVista Strategies LLC78,911$3.87M1.07%+78,911New
TD Asset Management Inc75,696$3.71M0.00%−4,200−5.3%Reduced
Standard Life Aberdeen plc75,680$3.71M0.01%00.0%Unchanged
B Group, Inc.75,000$3.68M2.73%00.0%Unchanged
American Century Companies Inc74,386$3.65M0.00%+17,306+30.3%Added
Manufacturers Life Insurance Company, The72,563$3.56M0.00%+11,205+18.3%Added
Secure Asset Management, LLC72,422$3.55M0.56%−9,242−11.3%Reduced
Boothbay Fund Management, LLC67,481$3.31M0.08%+67,481New
Voya Investment Management LLC66,600$3.27M0.00%+24,097+56.7%Added
Superstring Capital Management LP63,591$3.12M2.23%+63,591New
Palo Alto Investors LP59,985$2.94M0.45%00.0%Unchanged
EAM Investors, LLC59,946$2.94M0.34%+59,946New
Rhumbline Advisers46,356$2.27M0.00%+5,339+13.0%Added
Russell Investments Group, Ltd.45,459$2.23M0.00%+42,418+1,394.9%Added
Fred Alger Management, LLC43,841$2.15M0.01%+43,841New
Swiss National Bank43,000$2.11M0.00%00.0%Unchanged
Martingale Asset Management L P42,732$2.10M0.05%+42,732New
Voleon Capital Management LP40,539$1.99M0.04%+16,991+72.2%Added
Rafferty Asset Management, LLC40,487$1.99M0.01%+2,002+5.2%Added
Alps Advisors Inc39,404$1.93M0.01%−347−0.9%Reduced
Y-Intercept (Hong Kong) Ltd36,912$1.81M0.03%+36,912New
Schroder Investment Management Group29,184$1.33M0.00%00.0%Unchanged
Alliancebernstein L.P.40,400$1.22M0.00%+2,600+6.9%Added
Squarepoint Ops LLC24,463$1.20M0.00%−3,208−11.6%Reduced
Envestnet Asset Management Inc23,667$1.16M0.00%+8,420+55.2%Added
SEI Investments Co22,840$1.12M0.00%+13,164+136.0%Added
Glenmede Trust Co NA21,772$1.07M0.01%+2,287+11.7%Added
California State Teachers Retirement System21,370$1.05M0.00%−288−1.3%Reduced
Vanguard Global Advisers, LLC21,370$1.05M0.00%+21,370New
MetLife Investment Management21,363$1.05M0.01%+10.0%Added
JPMorgan Chase & Co22,620$1.03M0.00%+2,203+10.8%Added
Susquehanna International Group, LLP20,984$1.03M0.00%+12,319+142.2%Added
ADAR1 Capital Management, LLC20,840$1.02M0.06%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.20,964$1.02M0.00%+812+4.0%Added
XTX Topco Ltd20,180$989.8K0.02%+20,180New
Two Sigma Investments, LP19,364$949.8K0.00%−9,202−32.2%Reduced
Profund Advisors LLC18,336$899.4K0.03%+3,713+25.4%Added
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management18,229$894.1K0.02%+2,823+18.3%Added
State of Wisconsin Investment Board18,099$887.8K0.00%−4,869−21.2%Reduced
UBS Asset Management Americas Inc16,902$829.0K0.00%+2,658+18.7%Added