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Oruka Therapeutics, Inc.

ORKA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000907654

In the last 90 days, Oruka Therapeutics, Inc. insiders filed 0 open-market purchases and 16 sales; 255 institutions reported holding it in 13F filings for Q2 2026, worth $7.05B in total; Viking Global Investors is the only superinvestor holding it.

13F holders, Q3 2025

Institutional positions in Oruka Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
105
+24 vs. Q2 2025
Shares held
45.6M
+11.1M (+32.3%) vs. Q2 2025
Total value
$875.8M
+$489.9M (+126.9%) vs. Q2 2025
New holders
32
31 more added
Sold out
8
22 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ORKA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 105 institutions
Q1 2021: 17 institutionsQ2 2021: 17 institutionsQ3 2021: 19 institutionsQ4 2021: 21 institutionsQ1 2022: 22 institutionsQ2 2022: 24 institutionsQ3 2022: 25 institutionsQ4 2022: 22 institutionsQ1 2023: 26 institutionsQ2 2023: 23 institutionsQ3 2023: 21 institutionsQ4 2023: 25 institutionsQ1 2024: 23 institutionsQ2 2024: 32 institutionsQ3 2024: 42 institutionsQ4 2024: 66 institutionsQ1 2025: 71 institutionsQ2 2025: 81 institutionsQ3 2025: 105 institutionsQ4 2025: 143 institutionsQ1 2026: 184 institutionsQ2 2026: 255 institutions
Value heldQ3 2025: $875.8M
Q1 2021: $3.20MQ2 2021: $4.16MQ3 2021: $4.53MQ4 2021: $2.41MQ1 2022: $2.60MQ2 2022: $4.17MQ3 2022: $4.58MQ4 2022: $6.19MQ1 2023: $5.02MQ2 2023: $5.75MQ3 2023: $6.55MQ4 2023: $12.7MQ1 2024: $12.7MQ2 2024: $49.4MQ3 2024: $604.2MQ4 2024: $606.6MQ1 2025: $326.1MQ2 2025: $386.0MQ3 2025: $875.8MQ4 2025: $1.60BQ1 2026: $2.55BQ2 2026: $7.05B
Institutions holding ORKA and their total value by quarter
QuarterHoldersValue
Q2 2026255$7.05B
Q1 2026184$2.55B
Q4 2025143$1.60B
Q3 2025105$875.8M
Q2 202581$386.0M
Q1 202571$326.1M
Q4 202466$606.6M
Q3 202442$604.2M
Q2 202432$49.4M
Q1 202423$12.7M
Q4 202325$12.7M
Q3 202321$6.55M
Q2 202323$5.75M
Q1 202326$5.02M
Q4 202222$6.19M
Q3 202225$4.58M
Q2 202224$4.17M
Q1 202222$2.60M
Q4 202121$2.41M
Q3 202119$4.53M
Q2 202117$4.16M
Q1 202117$3.20M

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Oruka Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding ORKA in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC7,257,621$139.6M0.01%+1,641,150+29.2%Added
VR Adviser, LLC4,148,428$79.8M4.49%00.0%Unchanged
Fairmount Funds Management LLC3,705,262$71.3M6.41%+333,340+9.9%Added
Viking Global Investors LPSuperinvestorViking Global Investors2,666,690$51.3M0.13%+2,666,690New
Deep Track Capital, LP2,654,781$51.1M1.42%+735,983+38.4%Added
BlackRock, Inc.2,204,551$42.4M0.00%+215,671+10.8%Added
RTW Investments, LP1,945,649$37.4M0.46%00.0%Unchanged
Vanguard Group Inc1,776,665$34.2M0.00%−40,642−2.2%Reduced
Commodore Capital LP1,753,054$33.7M1.65%+333,340+23.5%Added
Braidwell LP1,382,350$26.6M0.79%−142,492−9.3%Reduced
Avoro Capital Advisors LLC1,333,340$25.6M0.33%+1,333,340New
Perceptive Advisors LLC1,268,021$24.4M0.70%+1,268,021New
Franklin Resources Inc1,065,782$20.5M0.01%+52,814+5.2%Added
Point72 Asset Management, L.P.1,037,002$19.9M0.04%+707,002+214.2%Added
Polar Capital Holdings Plc1,032,307$19.9M0.10%+57,307+5.9%Added
Affinity Asset Advisors, LLC959,180$18.4M1.72%+355,701+58.9%Added
Mercer Global Advisors Inc852,411$16.4M0.03%+730.0%Added
Blackstone Group Inc.850,400$16.4M0.07%+23,676+2.9%Added
Geode Capital Management, LLC689,972$13.3M0.00%−17,434−2.5%Reduced
Avidity Partners Management LP660,424$12.7M2.89%+308,300+87.6%Added
State Street Corp652,028$12.5M0.00%+279,222+74.9%Added
Price T Rowe Associates Inc626,806$12.1M0.00%+215,925+52.6%Added
Woodline Partners LP574,330$11.0M0.05%+183,426+46.9%Added
Cormorant Asset Management, LP533,340$10.3M0.71%+533,340New
Cable Car Capital LLC500,000$9.62M4.12%−100,000−16.7%Reduced
Sr One Capital Management, LP430,330$8.28M1.20%00.0%Unchanged
Candriam Luxembourg S.C.A.366,994$7.06M0.04%+250,296+214.5%Added
Citadel Advisors LLC316,886$6.09M0.00%+316,886New
Charles Schwab Investment Management Inc246,926$4.75M0.00%+162,924+194.0%Added
Northern Trust Corp219,709$4.23M0.00%−2,469−1.1%Reduced
Great Point Partners LLC183,330$3.53M1.47%+183,330New
Morgan Stanley134,833$2.59M0.00%−73,495−35.3%Reduced
D. E. Shaw & Co., Inc.95,417$1.83M0.00%+27,772+41.1%Added
Barclays PLC95,330$1.83M0.00%+4,166+4.6%Added
Wellington Management Group LLP91,094$1.75M0.00%+91,094New
UBS Group AG86,560$1.66M0.00%−24,086−21.8%Reduced
Bank of America Corp78,995$1.52M0.00%+60,146+319.1%Added
Standard Life Aberdeen plc75,680$1.46M0.00%−2,700−3.4%Reduced
B Group, Inc.75,000$1.44M1.38%00.0%Unchanged
Resolute Capital Asset Partners LLC75,000$1.44M0.75%+75,000New
Bank of New York Mellon Corp70,632$1.36M0.00%+7,123+11.2%Added
Jefferies Financial Group Inc.64,991$1.25M0.01%00.0%Unchanged
Toronto Dominion Bank58,332$1.12M0.00%00.0%Unchanged
Manufacturers Life Insurance Company, The51,908$998.2K0.00%−839−1.6%Reduced
Kennedy Capital Management, Inc.48,266$928.2K0.02%−16,660−25.7%Reduced
TD Asset Management Inc45,876$882.2K0.00%00.0%Unchanged
Palo Alto Investors LP59,985$791.3K0.15%+59,985New
Financial Enhancement Group LLC32,819$742.2K0.10%+32,819New
Nuveen, LLC35,313$679.1K0.00%00.0%Unchanged
American Century Companies Inc34,111$656.0K0.00%+34,111New
Rhumbline Advisers30,327$583.2K0.00%+1,757+6.1%Added
Schroder Investment Management Group29,184$563.0K0.00%+29,184New
Two Sigma Investments, LP28,566$549.3K0.00%−3,776−11.7%Reduced
Deutsche Bank AG22,119$425.3K0.00%+2,758+14.2%Added
Wells Fargo & Company20,856$401.1K0.00%+3,401+19.5%Added
ADAR1 Capital Management, LLC20,840$400.8K0.04%−121,940−85.4%Reduced
Goldman Sachs Group Inc19,775$380.3K0.00%−52,474−72.6%Reduced
MetLife Investment Management16,513$317.5K0.00%00.0%Unchanged
Invesco Ltd.16,318$313.8K0.00%+1,008+6.6%Added
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management15,406$296.3K0.01%+15,406New
JPMorgan Chase & Co14,479$278.4K0.00%−946−6.1%Reduced
Altfest L J & Co Inc13,297$255.7K0.03%+13,297New
Mirae Asset Global ETFs Holdings Ltd.13,143$252.8K0.00%−1,749−11.7%Reduced
Rafferty Asset Management, LLC12,787$245.9K0.00%+12,787New
Intech Investment Management LLC12,506$240.5K0.00%−2,519−16.8%Reduced
Quest Partners LLC10,761$206.9K0.01%−5,303−33.0%Reduced
New York State Common Retirement Fund8,600$165.4K0.00%00.0%Unchanged
Police & Firemen's Retirement System of New Jersey7,358$141.5K0.00%+1,250+20.5%Added
China Universal Asset Management Co., Ltd.6,565$126.2K0.01%−955−12.7%Reduced
BNP Paribas Arbitrage, SA5,747$110.5K0.00%+2,944+105.0%Added
Citigroup Inc3,371$64.8K0.00%−6,469−65.7%Reduced
Ameritas Investment Partners, Inc.2,777$53.4K0.00%00.0%Unchanged
Legal & General Group Plc2,477$47.6K0.00%00.0%Unchanged
Russell Investments Group, Ltd.2,253$43.3K0.00%+2,253New
Tower Research Capital LLC (TRC)2,218$42.7K0.00%−131−5.6%Reduced
The PNC Financial Services Group, Inc.2,014$38.7K0.00%+2,014New
Caption Management, LLC2,000$38.5K0.00%+2,000New
Sterling Capital Management LLC1,877$36.1K0.00%+1,143+155.7%Added
California State Teachers Retirement System1,698$32.7K0.00%+1+0.1%Added
Mirae Asset Global Investments Co., Ltd.1,448$27.8K0.00%+2+0.1%Added
Stone House Investment Management, LLC1,000$19.2K0.00%+1,000New
Amalgamated Bank929$18.0K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.806$15.5K0.00%−90−10.0%Reduced
Royal Bank of Canada774$14.0K0.00%−1,730−69.1%Reduced
Simplex Trading, LLC729$14.0K0.00%+729New
CWM, LLC394$8.00K0.00%+394New
US Bancorp178$3.42K0.00%+178New
Activest Wealth Management166$3.19K0.00%00.0%Unchanged
Daiwa Securities Group Inc.116$2.00K0.00%00.0%Unchanged
Group One Trading, L.P.100$1.92K0.00%+100New
SRS Capital Advisors, Inc.72$1.39K0.00%+72New
Rise Advisors, LLC36$6920.00%+36New
Essential Partners LLC27$5190.00%+27New
True Wealth Design, LLC26$5000.00%+26New
J.Safra Asset Management Corp24$4620.00%00.0%Unchanged
Parallel Advisors, LLC20$3850.00%00.0%Unchanged
EverSource Wealth Advisors, LLC16$3080.00%+16New
Larson Financial Group LLC11$2120.00%+11New
Farther Finance Advisors, LLC10$1920.00%+10New
National Bank of Canada8$1530.00%00.0%Unchanged