Oruka Therapeutics, Inc.

ORKA

Exchange: Nasdaq
Industry: Pharmaceutical Preparations
SEC CIK: 0000907654

SEC filings (opens in a new tab)

In the last 90 days, Oruka Therapeutics, Inc. insiders filed 0 open-market purchases and 15 sales; 255 institutions reported holding it in 13F filings for Q2 2026, worth $7.05B in total; Viking Global Investors is the only superinvestor holding it.

Q3 2025 vs. Q2 2025

How the institutions holding Oruka Therapeutics, Inc. changed between Q2 2025 and Q3 2025.

All holders in Q3 2025 All holders in Q2 2025

13F holders of ORKA: Q2 2025 compared with Q3 2025
Measure	Q2 2025	Q3 2025	Change
Holders	81	105	+24
Shares	34.4M	45.6M	+11.1M (+32.3%)
Value	$386.0M	$875.8M	+$489.9M (+126.9%)

New holders (32)

Institutions that held Oruka Therapeutics, Inc. at the end of Q3 2025 but not at the end of Q2 2025.

Institutions new to ORKA in Q3 2025
Institution	Shares	Value	% of portfolio
Viking Global Investors LPSuperinvestorViking Global Investors	2,666,690	$51.3M	0.13%
Avoro Capital Advisors LLC	1,333,340	$25.6M	0.33%
Perceptive Advisors LLC	1,268,021	$24.4M	0.70%
Cormorant Asset Management, LP	533,340	$10.3M	0.71%
Citadel Advisors LLC	316,886	$6.09M	0.00%
Great Point Partners LLC	183,330	$3.53M	1.47%
Wellington Management Group LLP	91,094	$1.75M	0.00%
Resolute Capital Asset Partners LLC	75,000	$1.44M	0.75%
Palo Alto Investors LP	59,985	$791.3K	0.15%
Financial Enhancement Group LLC	32,819	$742.2K	0.10%
American Century Companies Inc	34,111	$656.0K	0.00%
Schroder Investment Management Group	29,184	$563.0K	0.00%
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management	15,406	$296.3K	0.01%
Altfest L J & Co Inc	13,297	$255.7K	0.03%
Rafferty Asset Management, LLC	12,787	$245.9K	0.00%
Russell Investments Group, Ltd.	2,253	$43.3K	0.00%
The PNC Financial Services Group, Inc.	2,014	$38.7K	0.00%
Caption Management, LLC	2,000	$38.5K	0.00%
Stone House Investment Management, LLC	1,000	$19.2K	0.00%
Simplex Trading, LLC	729	$14.0K	0.00%
CWM, LLC	394	$8.00K	0.00%
US Bancorp	178	$3.42K	0.00%
Group One Trading, L.P.	100	$1.92K	0.00%
SRS Capital Advisors, Inc.	72	$1.39K	0.00%
Rise Advisors, LLC	36	$692	0.00%
Essential Partners LLC	27	$519	0.00%
True Wealth Design, LLC	26	$500	0.00%
EverSource Wealth Advisors, LLC	16	$308	0.00%
Larson Financial Group LLC	11	$212	0.00%
Farther Finance Advisors, LLC	10	$192	0.00%
IFP Advisors, Inc	3	$58	0.00%
CIBC Private Wealth Group, LLC	1	$19	0.00%

Sold out (8)

Institutions that held Oruka Therapeutics, Inc. at the end of Q2 2025 and filed for Q3 2025 without it.

Institutions that sold out of ORKA in Q3 2025
Institution	Shares, Q2 2025	Value, Q2 2025
Frazier Life Sciences Management, L.P.	583,327	$6.54M
Silverarc Capital Management, LLC	165,389	$1.85M
Ikarian Capital, LLC	68,574	$768.7K
Susquehanna International Group, LLP	33,962	$380.7K
Boothbay Fund Management, LLC	19,003	$213.0K
Renaissance Technologies LLC	13,900	$155.8K
Millennium Management LLC	12,326	$138.2K
Caitong International Asset Management Co., Ltd	1	$11