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Oruka Therapeutics, Inc.

ORKA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000907654

In the last 90 days, Oruka Therapeutics, Inc. insiders filed 0 open-market purchases and 16 sales; 255 institutions reported holding it in 13F filings for Q2 2026, worth $7.05B in total; Viking Global Investors is the only superinvestor holding it.

13F holders, Q4 2024

Institutional positions in Oruka Therapeutics, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
66
+24 vs. Q3 2024
Shares held
31.0M
+6.48M (+26.4%) vs. Q3 2024
Total value
$606.6M
+$2.45M (+0.4%) vs. Q3 2024
New holders
29
20 more added
Sold out
5
8 more reduced

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ORKA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 66 institutions
Q1 2021: 17 institutionsQ2 2021: 17 institutionsQ3 2021: 19 institutionsQ4 2021: 21 institutionsQ1 2022: 22 institutionsQ2 2022: 24 institutionsQ3 2022: 25 institutionsQ4 2022: 22 institutionsQ1 2023: 26 institutionsQ2 2023: 23 institutionsQ3 2023: 21 institutionsQ4 2023: 25 institutionsQ1 2024: 23 institutionsQ2 2024: 32 institutionsQ3 2024: 42 institutionsQ4 2024: 66 institutionsQ1 2025: 71 institutionsQ2 2025: 81 institutionsQ3 2025: 105 institutionsQ4 2025: 143 institutionsQ1 2026: 184 institutionsQ2 2026: 255 institutions
Value heldQ4 2024: $606.6M
Q1 2021: $3.20MQ2 2021: $4.16MQ3 2021: $4.53MQ4 2021: $2.41MQ1 2022: $2.60MQ2 2022: $4.17MQ3 2022: $4.58MQ4 2022: $6.19MQ1 2023: $5.02MQ2 2023: $5.75MQ3 2023: $6.55MQ4 2023: $12.7MQ1 2024: $12.7MQ2 2024: $49.4MQ3 2024: $604.2MQ4 2024: $606.6MQ1 2025: $326.1MQ2 2025: $386.0MQ3 2025: $875.8MQ4 2025: $1.60BQ1 2026: $2.55BQ2 2026: $7.05B
Institutions holding ORKA and their total value by quarter
QuarterHoldersValue
Q2 2026255$7.05B
Q1 2026184$2.55B
Q4 2025143$1.60B
Q3 2025105$875.8M
Q2 202581$386.0M
Q1 202571$326.1M
Q4 202466$606.6M
Q3 202442$604.2M
Q2 202432$49.4M
Q1 202423$12.7M
Q4 202325$12.7M
Q3 202321$6.55M
Q2 202323$5.75M
Q1 202326$5.02M
Q4 202222$6.19M
Q3 202225$4.58M
Q2 202224$4.17M
Q1 202222$2.60M
Q4 202121$2.41M
Q3 202119$4.53M
Q2 202117$4.16M
Q1 202117$3.20M

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Oruka Therapeutics, Inc.; share changes are against Q3 2024.

Institutions holding ORKA in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC5,512,300$106.9M0.01%+830,000+17.7%Added
Fairmount Funds Management LLC3,371,922$65.4M6.50%+160,000+5.0%Added
VR Adviser, LLC3,285,620$63.7M4.37%+200,000+6.5%Added
RTW Investments, LP1,945,649$37.7M0.57%+95,001+5.1%Added
Vanguard Group Inc1,610,651$31.2M0.00%+1,572,853+4,161.2%Added
Commodore Capital LP1,419,714$27.5M2.02%+50,000+3.7%Added
Braidwell LP1,147,676$27.1M0.80%+631,950+122.5%Added
Price T Rowe Associates Inc1,326,893$25.7M0.00%+1,047,245+374.5%Added
Janus Henderson Group PLC849,410$16.4M0.01%+613,294+259.7%Added
Perceptive Advisors LLC845,567$16.4M0.46%−389,620−31.5%Reduced
Paradigm Biocapital Advisors LP819,660$15.9M0.55%+100,000+13.9%Added
BlackRock, Inc.751,431$14.6M0.00%+729,864+3,384.2%Added
Deep Track Capital, LP750,000$14.5M0.55%−485,187−39.3%Reduced
Franklin Resources Inc720,547$14.0M0.00%00.0%Unchanged
Frazier Life Sciences Management, L.P.583,327$11.3M0.47%+106,000+22.2%Added
Polar Capital Holdings Plc550,000$10.7M0.06%+550,000New
Sr One Capital Management, LP430,330$8.34M2.03%+55,000+14.7%Added
Redmile Group, LLC411,728$7.98M0.56%00.0%Unchanged
Morgan Stanley405,998$7.87M0.00%+337,865+495.9%Added
Woodline Partners LP390,969$7.58M0.05%+1740.0%Added
Affinity Asset Advisors, LLC368,698$7.15M1.12%+18,862+5.4%Added
Point72 Asset Management, L.P.360,732$6.99M0.02%−121,598−25.2%Reduced
Avidity Partners Management LP352,124$6.83M0.68%−438,802−55.5%Reduced
Jefferies Financial Group Inc.350,029$6.79M0.08%+350,029New
Geode Capital Management, LLC342,418$6.64M0.00%+328,434+2,348.6%Added
Cable Car Capital LLC333,371$6.46M0.49%00.0%Unchanged
Driehaus Capital Management LLC308,795$5.99M0.05%00.0%Unchanged
Blackstone Group Inc.240,174$4.66M0.02%+240,174New
Great Point Partners LLC228,803$4.44M2.09%−285,856−55.5%Reduced
Qube Research & Technologies Ltd152,082$2.95M0.00%+110,722+267.7%Added
Wellington Management Group LLP95,089$1.84M0.00%+12,952+15.8%Added
TD Asset Management Inc95,076$1.84M0.00%00.0%Unchanged
Barclays PLC74,583$1.45M0.00%+74,583New
Adage Capital Partners GP, L.L.C.69,200$1.34M0.00%−130,800−65.4%Reduced
Northern Trust Corp64,044$1.24M0.00%+64,044New
Kennedy Capital Management, Inc.60,494$1.17M0.03%+60,494New
Toronto Dominion Bank58,332$1.13M0.00%+58,332New
Manufacturers Life Insurance Company, The42,298$820.2K0.00%00.0%Unchanged
Weiss Asset Management LP40,000$775.6K0.02%+40,000New
683 Capital Management, LLC33,875$656.8K0.06%+33,875New
Millennium Management LLC30,305$587.6K0.00%+30,305New
UBS Group AG25,162$487.9K0.00%+25,162New
State Street Corp25,023$485.2K0.00%+25,023New
Ensign Peak Advisors, Inc25,000$484.8K0.00%00.0%Unchanged
Allostery Investments LP20,000$387.8K0.76%+20,000New
B Group, Inc.20,000$387.8K0.24%+20,000New
Omers Administration Corp19,800$383.9K0.00%+19,800New
Jane Street Group, LLC17,706$343.3K0.00%+17,706New
Charles Schwab Investment Management Inc15,608$302.6K0.00%+15,608New
Squarepoint Ops LLC12,175$236.1K0.00%+12,175New
Citigroup Inc8,028$155.7K0.00%−18,692−70.0%Reduced
China Universal Asset Management Co., Ltd.7,421$143.9K0.01%+7,421New
AlphaCentric Advisors LLC6,140$119.1K0.12%+6,140New
JPMorgan Chase & Co2,800$54.3K0.00%+2,800New
Mirae Asset Global Investments Co., Ltd.1,166$22.2K0.00%+1,166New
GF Fund Management Co. Ltd.735$14.3K0.00%+735New
Tower Research Capital LLC (TRC)584$11.3K0.00%−381−39.5%Reduced
BNP Paribas Arbitrage, SA468$9.07K0.00%+468New
Bank of America Corp198$3.84K0.00%+183+1,220.0%Added
Activest Wealth Management166$3.22K0.00%00.0%Unchanged
Daiwa Securities Group Inc.116$2.00K0.00%+116New
Royal Bank of Canada55$1.00K0.00%+55New
Group One Trading, L.P.23$4460.00%+23New
Parallel Advisors, LLC20$3880.00%00.0%Unchanged
National Bank of Canada8$1550.00%+8New
Aster Capital Management (DIFC) Ltd5$970.00%+5New
Logos Global Management LP0$00.00%−257,330−100.0%Sold out
Cowen and Company, LLC0$00.00%−58,332−100.0%Sold out
ADAR1 Capital Management, LLC0$00.00%−11,187−100.0%Sold out
New England Capital Financial Advisors LLC0$00.00%−41−100.0%Sold out
Danske Bank A/S0$00.00%−2−100.0%Sold out