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Oruka Therapeutics, Inc.

ORKA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000907654

In the last 90 days, Oruka Therapeutics, Inc. insiders filed 0 open-market purchases and 15 sales; 255 institutions reported holding it in 13F filings for Q2 2026, worth $7.05B in total; Viking Global Investors is the only superinvestor holding it.

Q4 2025 vs. Q3 2025

How the institutions holding Oruka Therapeutics, Inc. changed between Q3 2025 and Q4 2025.

All holders in Q4 2025All holders in Q3 2025

13F holders of ORKA: Q3 2025 compared with Q4 2025
MeasureQ3 2025Q4 2025Change
Holders105143+38
Shares45.6M52.9M+7.29M (+16.0%)
Value$875.8M$1.60B+$726.2M (+82.9%)

New holders (46)

Institutions that held Oruka Therapeutics, Inc. at the end of Q4 2025 but not at the end of Q3 2025.

Institutions new to ORKA in Q4 2025
InstitutionSharesValue% of portfolio
Paradigm Biocapital Advisors LP1,710,316$51.8M1.39%
Remedium Capital Partners, LLC1,552,414$47.1M27.64%
Synergy Financial Management, LLC458,946$13.9M1.45%
Soleus Capital Management, L.P.190,000$5.76M0.24%
Longaeva Partners L.P.128,110$3.88M0.46%
Moody Aldrich Partners LLC126,812$3.84M0.72%
Kalehua Capital Management LLC118,524$3.59M3.55%
Sio Capital Management, LLC118,126$3.58M0.59%
Alyeska Investment Group, L.P.100,000$3.03M0.01%
Secure Asset Management, LLC81,664$2.48M0.39%
Millennium Management LLC58,723$1.78M0.00%
Swiss National Bank43,000$1.30M0.00%
Voya Investment Management LLC42,503$1.29M0.00%
Alps Advisors Inc39,751$1.20M0.01%
Alliancebernstein L.P.37,800$1.15M0.00%
Verition Fund Management LLC35,710$1.08M0.01%
Squarepoint Ops LLC27,671$838.7K0.00%
Voleon Capital Management LP23,548$713.7K0.02%
State of Wisconsin Investment Board22,968$696.2K0.00%
Hudson Bay Capital Management LP20,000$606.2K0.00%
Glenmede Trust Co NA19,485$590.6K0.00%
Brookwood Investment Group LLC16,569$502.2K0.06%
Envestnet Asset Management Inc15,247$462.1K0.00%
Profund Advisors LLC14,623$443.2K0.01%
UBS Asset Management Americas Inc14,244$431.7K0.00%
Janus Henderson Group PLC12,100$366.8K0.00%
AlphaCentric Advisors LLC10,880$329.8K0.33%
Allianz Asset Management GmbH10,300$312.2K0.00%
SEI Investments Co9,676$293.3K0.00%
Brevan Howard Capital Management LP9,416$285.4K0.01%
ProShare Advisors LLC9,189$278.5K0.00%
Virtus Investment Advisers, Inc.8,814$267.2K0.07%
Susquehanna International Group, LLP8,665$262.6K0.00%
SG Americas Securities, LLC8,275$251.0K0.00%
KLP Kapitalforvaltning AS8,000$242.5K0.00%
Creative Planning7,696$233.3K0.00%
Landscape Capital Management, L.L.C.7,447$225.7K0.02%
Seven Fleet Capital Management LP5,240$158.8K0.11%
Caitong International Asset Management Co., Ltd2,214$67.1K0.02%
Los Angeles Capital Management LLC1,302$36.6K0.00%
Balyasny Asset Management LLC536$16.2K0.00%
DV Trading LLC492$14.9K0.00%
Nisa Investment Advisors, LLC282$8.55K0.00%
GAMMA Investing LLC101$3.06K0.00%
Aster Capital Management (DIFC) Ltd25$7580.00%
Cornerstone Financial Management LLC21$6370.00%

Sold out (8)

Institutions that held Oruka Therapeutics, Inc. at the end of Q3 2025 and filed for Q4 2025 without it.

Institutions that sold out of ORKA in Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
Jefferies Financial Group Inc.64,991$1.25M
Toronto Dominion Bank58,332$1.12M
Caption Management, LLC2,000$38.5K
Simplex Trading, LLC729$14.0K
SRS Capital Advisors, Inc.72$1.39K
Rise Advisors, LLC36$692
National Bank of Canada8$153
SBI Securities Co., Ltd.6$115