Milestone Pharmaceuticals Inc.
MIST- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001408443
No open-market purchases or sales by Milestone Pharmaceuticals Inc. insiders were filed in the last 90 days; 78 institutions reported holding it in 13F filings for Q2 2026, worth $66.4M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Milestone Pharmaceuticals Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 87
- +7 vs. Q4 2025
- Shares held
- 39.5M
- +4.53M (+13.0%) vs. Q4 2025
- Total value
- $47.2M
- −$23.5M (−33.2%) vs. Q4 2025
- New holders
- 21
- 23 more added
- Sold out
- 14
- 19 more reduced
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting MIST on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 78 | $66.4M |
| Q1 2026 | 87 | $47.2M |
| Q4 2025 | 80 | $70.7M |
| Q3 2025 | 61 | $68.3M |
| Q2 2025 | 43 | $22.9M |
| Q1 2025 | 43 | $9.46M |
| Q4 2024 | 47 | $57.9M |
| Q3 2024 | 43 | $43.6M |
| Q2 2024 | 40 | $39.9M |
| Q1 2024 | 43 | $56.4M |
| Q4 2023 | 40 | $29.7M |
| Q3 2023 | 39 | $60.7M |
| Q2 2023 | 48 | $59.0M |
| Q1 2023 | 50 | $85.5M |
| Q4 2022 | 56 | $96.9M |
| Q3 2022 | 47 | $198.7M |
| Q2 2022 | 29 | $127.2M |
| Q1 2022 | 28 | $135.1M |
| Q4 2021 | 28 | $132.6M |
| Q3 2021 | 27 | $113.9M |
| Q2 2021 | 28 | $110.8M |
| Q1 2021 | 34 | $117.4M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Milestone Pharmaceuticals Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Pavaki Capital Management LLC | 9,062,848 | $10.8M | 7.58% | +563,933+6.6% | Added |
| RTW Investments, LP | 6,331,001 | $7.53M | 0.07% | +3,824,899+152.6% | Added |
| Propel Bio Management, LLC | 4,118,321 | $5.08M | 3.20% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 2,317,176 | $2.76M | 0.00% | +802,715+53.0% | Added |
| Goldman Sachs Group Inc | 2,000,025 | $2.38M | 0.00% | +2,000,025 | New |
| Marshall Wace, LLP | 1,944,530 | $2.31M | 0.00% | +287,709+17.4% | Added |
| Millennium Management LLC | 1,544,325 | $1.84M | 0.00% | +1,141,690+283.6% | Added |
| Simplify Asset Management Inc. | 1,506,405 | $1.79M | 0.03% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 1,085,683 | $1.29M | 0.00% | +603,328+125.1% | Added |
| Balyasny Asset Management LLC | 851,325 | $1.01M | 0.00% | +851,325 | New |
| Lion Point Capital, LP | 820,000 | $975.8K | 5.83% | +65,000+8.6% | Added |
| Toronto Dominion Bank | 750,000 | $892.5K | 0.00% | 00.0% | Unchanged |
| Morgan Stanley | 724,141 | $861.7K | 0.00% | −57,734−7.4% | Reduced |
| Boxer Capital Management, LLC | 666,666 | $793.3K | 0.10% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 666,666 | $793.3K | 0.00% | +666,666 | New |
| Susquehanna International Group, LLP | 519,046 | $617.7K | 0.00% | −124,254−19.3% | Reduced |
| UBS Group AG | 494,908 | $588.9K | 0.00% | +3,040+0.6% | Added |
| Squarepoint Ops LLC | 336,825 | $400.8K | 0.00% | +87,481+35.1% | Added |
| Seven Fleet Capital Management LP | 333,333 | $396.7K | 0.12% | +333,333 | New |
| Aptus Capital Advisors, LLC | 280,250 | $333.5K | 0.00% | +17,050+6.5% | Added |
| Guardian Wealth Advisors, LLC | 280,250 | $333.5K | 0.02% | +17,050+6.5% | Added |
| Citadel Advisors LLC | 196,696 | $234.1K | 0.00% | −156,536−44.3% | Reduced |
| LPL Financial LLC | 193,373 | $230.1K | 0.00% | +50,910+35.7% | Added |
| BNP Paribas Arbitrage, SA | 176,504 | $210.0K | 0.00% | −45,447−20.5% | Reduced |
| Boothbay Fund Management, LLC | 168,675 | $200.7K | 0.00% | +168,675 | New |
| Jane Street Group, LLC | 159,669 | $190.0K | 0.00% | −933,561−85.4% | Reduced |
| Simplex Trading, LLC | 149,291 | $177.7K | 0.01% | +149,291 | New |
| Quadrature Capital Ltd | 149,105 | $177.4K | 0.00% | +149,105 | New |
| Valeo Financial Advisors, LLC | 130,699 | $155.5K | 0.00% | 00.0% | Unchanged |
| Group One Trading, L.P. | 129,764 | $154.4K | 0.01% | −65,335−33.5% | Reduced |
| Renaissance Technologies LLC | 129,705 | $154.3K | 0.00% | +129,705 | New |
| XTX Topco Ltd | 120,602 | $143.5K | 0.00% | −51,358−29.9% | Reduced |
| ADAR1 Capital Management, LLC | 100,000 | $119.0K | 0.01% | −100−0.1% | Reduced |
| Tru Independence Asset Management 2, LLC | 100,000 | $119.0K | 0.07% | 00.0% | Unchanged |
| HRT Financial LP | 62,256 | $74.0K | 0.00% | +62,256 | New |
| Cambridge Investment Research Advisors, Inc. | 59,620 | $71.0K | 0.00% | +12,480+26.5% | Added |
| October Effect Ltd | 51,950 | $61.8K | 0.07% | −150−0.3% | Reduced |
| SG Americas Securities, LLC | 42,512 | $51.0K | 0.00% | −54,863−56.3% | Reduced |
| Invesco Ltd. | 41,356 | $49.2K | 0.00% | +19,463+88.9% | Added |
| Geode Capital Management, LLC | 40,789 | $48.5K | 0.00% | −33,233−44.9% | Reduced |
| Northern Trust Corp | 38,779 | $46.1K | 0.00% | −479−1.2% | Reduced |
| Colony Group, LLC | 36,000 | $42.8K | 0.00% | 00.0% | Unchanged |
| Mariner, LLC | 30,830 | $36.7K | 0.00% | +5,830+23.3% | Added |
| Bay Rivers Group | 29,911 | $35.6K | 0.01% | +1,050+3.6% | Added |
| Federation des caisses Desjardins du Quebec | 29,781 | $35.4K | 0.00% | 00.0% | Unchanged |
| Gsa Capital Partners LLP | 26,893 | $32.0K | 0.00% | −209,245−88.6% | Reduced |
| Raymond James Financial Inc | 26,600 | $31.7K | 0.00% | 00.0% | Unchanged |
| Safeguard Investment Advisory Group, LLC | 25,044 | $29.8K | 0.01% | 00.0% | Unchanged |
| Welch & Forbes LLC | 25,000 | $29.8K | 0.00% | +25,000 | New |
| National Bank of Canada | 23,500 | $28.0K | 0.00% | +4,800+25.7% | Added |
| State Street Corp | 22,331 | $26.6K | 0.00% | +456+2.1% | Added |
| Acadian Asset Management LLC | 20,468 | $24.0K | 0.00% | −155,732−88.4% | Reduced |
| Journey Strategic Wealth LLC | 20,000 | $23.8K | 0.00% | 00.0% | Unchanged |
| Stephenson & Company, Inc. | 20,000 | $23.8K | 0.01% | 00.0% | Unchanged |
| Pathstone Holdings, LLC | 17,040 | $20.3K | 0.00% | −1,000,000−98.3% | Reduced |
| SJS Investment Consulting Inc. | 15,000 | $17.9K | 0.00% | 00.0% | Unchanged |
| Taylor Financial Group, Inc. | 15,000 | $17.9K | 0.01% | +5,000+50.0% | Added |
| AE Wealth Management LLC | 15,000 | $17.9K | 0.00% | +15,000 | New |
| Vision Retirement, LLC | 15,000 | $17.9K | 0.01% | +15,000 | New |
| Exit Wealth Advisors, LLC. | 15,000 | $17.9K | 0.01% | +15,000 | New |
| Capital Performance Advisors LLP | 14,756 | $17.6K | 0.00% | +14,756 | New |
| Cetera Investment Advisers | 14,704 | $17.5K | 0.00% | −6,018−29.0% | Reduced |
| Beta Wealth Group, Inc. | 14,127 | $16.8K | 0.01% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 16,000 | $16.6K | 0.00% | 00.0% | Unchanged |
| Strategic Family Wealth Counselors, L.L.C. | 13,875 | $16.5K | 0.00% | +1,200+9.5% | Added |
| Creative Planning | 13,410 | $16.0K | 0.00% | −10,000−42.7% | Reduced |
| Rockefeller Capital Management L.P. | 12,500 | $14.9K | 0.00% | +10,800+635.3% | Added |
| IMC-Chicago, LLC | 10,943 | $13.0K | 0.00% | +10,943 | New |
| Wealthspire Advisors, LLC | 10,629 | $12.6K | 0.00% | +10,629 | New |
| Bronte Capital Management Pty Ltd. | 10,414 | $12.4K | 0.00% | 00.0% | Unchanged |
| Eaton Financial Holdings Company, LLC | 10,250 | $12.2K | 0.00% | −2,500−19.6% | Reduced |
| Bayesian Capital Management, LP | 10,015 | $11.9K | 0.01% | −7,200−41.8% | Reduced |
| Ancora Advisors, LLC | 10,000 | $11.9K | 0.00% | 00.0% | Unchanged |
| Secure Asset Management, LLC | 10,000 | $11.9K | 0.00% | 00.0% | Unchanged |
| Integral Investment Advisors, Inc. | 10,000 | $11.9K | 0.00% | 00.0% | Unchanged |
| HighTower Advisors, LLC | 10,000 | $11.9K | 0.00% | +10,000 | New |
| CWM, LLC | 10,000 | $11.9K | 0.00% | +10,000 | New |
| Tower Research Capital LLC (TRC) | 9,147 | $10.9K | 0.00% | +167+1.9% | Added |
| Royal Bank of Canada | 6,698 | $8.00K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 3,200 | $3.81K | 0.00% | 00.0% | Unchanged |
| Caitong International Asset Management Co., Ltd | 1,729 | $2.06K | 0.00% | +1,729 | New |
| The PNC Financial Services Group, Inc. | 1,000 | $1.19K | 0.00% | +1,000 | New |
| Medallion Wealth Advisors, LLC | 340 | $405 | 0.00% | 00.0% | Unchanged |
| Rialto Wealth Management, LLC | 300 | $357 | 0.00% | 00.0% | Unchanged |
| Key Capital Management, INC | 212 | $252 | 0.00% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 125 | $149 | 0.00% | +125 | New |
| SBI Securities Co., Ltd. | 11 | $13 | 0.00% | +5+83.3% | Added |
| Adage Capital Partners GP, L.L.C. | 0 | $0 | 0.00% | −2,810,037−100.0% | Sold out |
| Stonepine Capital Management, LLC | 0 | $0 | 0.00% | −662,666−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −619,592−100.0% | Sold out |
| Nomura Holdings Inc | 0 | $0 | 0.00% | −225,000−100.0% | Sold out |
| Graham Capital Management, L.P. | 0 | $0 | 0.00% | −133,620−100.0% | Sold out |
| Cascades Capital Asset Management, LLC | 0 | $0 | 0.00% | −77,510−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −59,053−100.0% | Sold out |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −34,596−100.0% | Sold out |
| Citigroup Inc | 0 | $0 | 0.00% | −33,858−100.0% | Sold out |
| Scientech Research LLC | 0 | $0 | 0.00% | −30,124−100.0% | Sold out |
| Quantbot Technologies LP | 0 | $0 | 0.00% | −18,990−100.0% | Sold out |
| AQR Capital Management LLC | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| SRS Capital Advisors, Inc. | 0 | $0 | 0.00% | −1,591−100.0% | Sold out |