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Milestone Pharmaceuticals Inc.

MIST
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001408443

No open-market purchases or sales by Milestone Pharmaceuticals Inc. insiders were filed in the last 90 days; 78 institutions reported holding it in 13F filings for Q2 2026, worth $68.1M in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Milestone Pharmaceuticals Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
78
−7 vs. Q1 2026
Shares held
50.8M
+11.3M (+28.7%) vs. Q1 2026
Total value
$68.1M
+$20.9M (+44.4%) vs. Q1 2026
New holders
6
23 more added
Sold out
13
23 more reduced

2 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MIST on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 78 institutions
Q1 2021: 34 institutionsQ2 2021: 28 institutionsQ3 2021: 27 institutionsQ4 2021: 28 institutionsQ1 2022: 28 institutionsQ2 2022: 29 institutionsQ3 2022: 47 institutionsQ4 2022: 56 institutionsQ1 2023: 50 institutionsQ2 2023: 48 institutionsQ3 2023: 39 institutionsQ4 2023: 40 institutionsQ1 2024: 43 institutionsQ2 2024: 40 institutionsQ3 2024: 43 institutionsQ4 2024: 47 institutionsQ1 2025: 43 institutionsQ2 2025: 43 institutionsQ3 2025: 61 institutionsQ4 2025: 80 institutionsQ1 2026: 87 institutionsQ2 2026: 78 institutions
Value heldQ2 2026: $68.1M
Q1 2021: $117.4MQ2 2021: $110.8MQ3 2021: $113.9MQ4 2021: $133.9MQ1 2022: $135.1MQ2 2022: $127.2MQ3 2022: $203.8MQ4 2022: $96.9MQ1 2023: $85.5MQ2 2023: $59.0MQ3 2023: $60.7MQ4 2023: $30.9MQ1 2024: $59.3MQ2 2024: $42.2MQ3 2024: $43.6MQ4 2024: $57.9MQ1 2025: $9.46MQ2 2025: $23.0MQ3 2025: $68.3MQ4 2025: $70.7MQ1 2026: $47.2MQ2 2026: $68.1M
Institutions holding MIST and their total value by quarter
QuarterHoldersValue
Q2 202678$68.1M
Q1 202687$47.2M
Q4 202580$70.7M
Q3 202561$68.3M
Q2 202543$23.0M
Q1 202543$9.46M
Q4 202447$57.9M
Q3 202443$43.6M
Q2 202440$42.2M
Q1 202443$59.3M
Q4 202340$30.9M
Q3 202339$60.7M
Q2 202348$59.0M
Q1 202350$85.5M
Q4 202256$96.9M
Q3 202247$203.8M
Q2 202229$127.2M
Q1 202228$135.1M
Q4 202128$133.9M
Q3 202127$113.9M
Q2 202128$110.8M
Q1 202134$117.4M

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Milestone Pharmaceuticals Inc.; share changes are against Q1 2026.

Institutions holding MIST in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Pavaki Capital Management LLC9,067,848$12.2M6.92%+5,000+0.1%Added
RTW Investments, LP7,833,336$10.5M0.09%+1,502,335+23.7%Added
Propel Bio Management, LLC7,429,590$9.96M5.21%+3,311,269+80.4%Added
Point72 Asset Management, L.P.5,411,138$7.25M0.01%+4,325,455+398.4%Added
Simplify Asset Management Inc.3,349,379$4.49M0.06%+1,842,974+122.3%Added
Millennium Management LLC3,142,219$4.21M0.00%+1,597,894+103.5%Added
Kalehua Capital Management LLC2,538,474$3.40M1.09%+2,538,474New
Two Sigma Investments, LP2,040,015$2.73M0.00%−277,161−12.0%Reduced
Marshall Wace, LLP1,797,695$2.41M0.00%−146,835−7.6%Reduced
Lion Point Capital, LP820,000$1.10M5.26%00.0%Unchanged
Toronto Dominion Bank750,000$1.00M0.00%00.0%Unchanged
Ameriprise Financial Inc666,666$893.3K0.00%00.0%Unchanged
Boxer Capital Management, LLC666,666$893.3K0.07%00.0%Unchanged
Morgan Stanley635,211$851.2K0.00%−88,930−12.3%Reduced
UBS Group AG465,403$623.6K0.00%−29,505−6.0%Reduced
Boothbay Fund Management, LLC462,669$620.0K0.01%+293,994+174.3%Added
Susquehanna International Group, LLP359,895$482.3K0.00%−159,151−30.7%Reduced
Aptus Capital Advisors, LLC339,450$454.9K0.00%+59,200+21.1%Added
Guardian Wealth Advisors, LLC339,450$454.9K0.03%+59,200+21.1%Added
Seven Fleet Capital Management LP270,233$362.1K0.06%−63,100−18.9%Reduced
Squarepoint Ops LLC231,824$310.6K0.00%−105,001−31.2%Reduced
LPL Financial LLC220,873$296.0K0.00%+27,500+14.2%Added
Balyasny Asset Management LLC220,498$295.5K0.00%−630,827−74.1%Reduced
BNP Paribas Arbitrage, SA173,704$232.8K0.00%−2,800−1.6%Reduced
Tru Independence Asset Management 2, LLC150,000$201.0K0.11%+50,000+50.0%Added
Wealthspire Advisors, LLC140,629$188.4K0.00%+130,000+1,223.1%Added
Valeo Financial Advisors, LLC130,699$175.1K0.00%00.0%Unchanged
ADAR1 Capital Management, LLC100,000$134.0K0.01%00.0%Unchanged
Cascades Capital Asset Management, LLC83,610$112.0K0.04%+83,610New
Quadrature Capital Ltd64,661$86.6K0.00%−84,444−56.6%Reduced
Jane Street Group, LLC57,787$77.4K0.00%−101,882−63.8%Reduced
Simplex Trading, LLC54,171$72.6K0.00%−95,120−63.7%Reduced
Bay Rivers Group46,633$62.5K0.02%+16,722+55.9%Added
SG Americas Securities, LLC45,574$61.0K0.00%+3,062+7.2%Added
Geode Capital Management, LLC40,789$54.7K0.00%00.0%Unchanged
October Effect Ltd40,000$53.6K0.05%−11,950−23.0%Reduced
Colony Group, LLC36,000$48.2K0.00%00.0%Unchanged
Citadel Advisors LLC32,887$44.1K0.00%−163,809−83.3%Reduced
Raymond James Financial Inc30,070$40.3K0.00%+3,470+13.0%Added
Federation des caisses Desjardins du Quebec29,781$39.9K0.00%00.0%Unchanged
Mariner, LLC27,830$37.2K0.00%−3,000−9.7%Reduced
Cambridge Investment Research Advisors, Inc.26,960$36.0K0.00%−32,660−54.8%Reduced
XTX Topco Ltd26,317$35.3K0.00%−94,285−78.2%Reduced
Welch & Forbes LLC25,000$33.5K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)24,185$32.4K0.00%+15,038+164.4%Added
National Bank of Canada23,500$31.5K0.00%00.0%Unchanged
Exit Wealth Advisors, LLC.22,692$30.4K0.01%+7,692+51.3%Added
State Street Corp22,564$30.2K0.00%+233+1.0%Added
Stephenson & Company, Inc.20,000$26.8K0.01%00.0%Unchanged
Taylor Financial Group, Inc.20,000$26.8K0.01%+5,000+33.3%Added
HighTower Advisors, LLC20,000$26.8K0.00%+10,000+100.0%Added
Two Sigma Securities, LLC16,745$22.4K0.00%+16,745New
Cetera Investment Advisers16,368$21.9K0.00%+1,664+11.3%Added
Pathstone Holdings, LLC15,500$20.8K0.00%−1,540−9.0%Reduced
AE Wealth Management LLC15,000$20.1K0.00%00.0%Unchanged
Vision Retirement, LLC15,000$20.1K0.00%00.0%Unchanged
Jones Financial Companies LLLP16,000$19.8K0.00%00.0%Unchanged
Capital Performance Advisors LLP14,756$19.8K0.00%00.0%Unchanged
Bronte Capital Management Pty Ltd.14,390$19.3K0.00%+3,976+38.2%Added
Winton Group Ltd14,300$19.2K0.00%+14,300New
Beta Wealth Group, Inc.14,127$18.9K0.01%00.0%Unchanged
Strategic Family Wealth Counselors, L.L.C.13,875$18.6K0.00%00.0%Unchanged
Creative Planning13,080$17.5K0.00%−330−2.5%Reduced
Rockefeller Capital Management L.P.12,500$16.8K0.00%00.0%Unchanged
Safeguard Investment Advisory Group, LLC12,406$16.6K0.00%−12,638−50.5%Reduced
Virtu Financial LLC11,613$16.0K0.00%+11,613New
Eaton Financial Holdings Company, LLC10,250$13.7K0.00%00.0%Unchanged
Secure Asset Management, LLC10,000$13.4K0.00%00.0%Unchanged
Integral Investment Advisors, Inc.10,000$13.4K0.00%00.0%Unchanged
Royal Bank of Canada6,698$9.00K0.00%00.0%Unchanged
US Bancorp3,200$4.29K0.00%00.0%Unchanged
SRS Capital Advisors, Inc.3,053$4.09K0.00%+3,053New
The PNC Financial Services Group, Inc.2,800$3.75K0.00%+1,800+180.0%Added
Medallion Wealth Advisors, LLC340$4560.00%00.0%Unchanged
Rialto Wealth Management, LLC300$4020.00%00.0%Unchanged
Group One Trading, L.P.224$3000.00%−129,540−99.8%Reduced
Caitong International Asset Management Co., Ltd94$1260.00%−1,635−94.6%Reduced
SBI Securities Co., Ltd.6$80.00%−5−45.5%Reduced
Goldman Sachs Group Inc0$00.00%−2,000,025−100.0%Sold out
Renaissance Technologies LLC0$00.00%−129,705−100.0%Sold out
HRT Financial LP0$00.00%−62,256−100.0%Sold out
Invesco Ltd.0$00.00%−41,356−100.0%Sold out
Northern Trust Corp0$00.00%−38,779−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−26,893−100.0%Sold out
Acadian Asset Management LLC0$00.00%−20,468−100.0%Sold out
SJS Investment Consulting Inc.0$00.00%−15,000−100.0%Sold out
IMC-Chicago, LLC0$00.00%−10,943−100.0%Sold out
Bayesian Capital Management, LP0$00.00%−10,015−100.0%Sold out
Ancora Advisors, LLC0$00.00%−10,000−100.0%Sold out
Key Capital Management, INC0$00.00%−212−100.0%Sold out
Russell Investments Group, Ltd.0$00.00%−125−100.0%Sold out
Journey Strategic Wealth LLC––––Not filed
CWM, LLC––––Not filed