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Milestone Pharmaceuticals Inc.

MIST
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001408443

No open-market purchases or sales by Milestone Pharmaceuticals Inc. insiders were filed in the last 90 days; 78 institutions reported holding it in 13F filings for Q2 2026, worth $66.4M in total; no superinvestor holds it.

Holders of 5% or more of MIST

Holders whose latest Schedule 13D or 13G filing reports 5% or more of Milestone Pharmaceuticals Inc., largest stake first. The change is against the holder's previous filing.

Holders of 5% or more of MIST
HolderLatest formStakeChangeFirst filedLatest filingFiling
Adage Capital Management, L.P.13G9.99%8.66M sharesNewNov 13, 20251 filingNov 13, 2025SEC
RTW Investments, LP13G/A9.90%9.16M shares−0.09 ppfrom 9.99%Feb 14, 20252 filingsNov 14, 2025SEC
Propel Bio Management, LLC13G9.90%8.86M sharesNewDec 23, 20251 filingDec 23, 2025SEC

Stakes are as of each holder's latest filing. Holders whose last filing was in the old format (before December 18, 2024) have no stake on record and are not listed, and after an acquisition or delisting holders usually stop filing.

13D and 13G filings

10 Schedule 13D and 13G filings on Milestone Pharmaceuticals Inc., newest first, including old-format filings without a stake.

Schedule 13D and 13G filings on MIST
Filed (ET)FilerFormStakeChangeEvent dateFiling
Mar 26, 20265:37 PM ETTrails Edge Capital Partners, LPand 2 others13G/A4.30%5.33M shares−5.60 ppfrom 9.90%Below 5%Mar 20, 2026SEC
Dec 23, 20252:20 PM ETPropel Bio Management, LLCand 3 others13G9.90%8.86M sharesNewJul 11, 2025SEC
Nov 14, 20254:05 PM ETTrails Edge Capital Partners, LPand 2 others13G/A9.90%9.02M shares0.00 ppfrom 9.90%Sep 30, 2025SEC
Nov 14, 20258:30 AM ETRTW Investments, LPand 1 other13G/A9.90%9.16M shares−0.09 ppfrom 9.99%Sep 30, 2025SEC
Nov 13, 20259:10 AM ETAdage Capital Management, L.P.and 2 others13G9.99%8.66M sharesNewSep 30, 2025SEC
Jul 21, 20254:30 PM ETTrails Edge Capital Partners, LPand 2 others13G9.90%8.85M sharesNewJul 14, 2025SEC
Apr 30, 20254:00 PM ETIntegrated Core Strategies (US) LLCand 3 others13G/A0.60%322.1K shares–Below 5%Mar 31, 2025SEC
Apr 22, 20259:32 AM ETBlackRock, Inc.13G/A0.00%0 shares−7.60 ppfrom 7.60%Below 5%Mar 31, 2025SEC
Feb 14, 20259:00 AM ETRTW Investments, LPand 1 other13G/A9.99%5.64M shares–Dec 31, 2024SEC
Feb 5, 20251:23 PM ETBlackRock, Inc.13G/A7.60%4.05M shares–Dec 31, 2024SEC

Form 144: proposed insider sales

Notices from officers, directors and other affiliates planning to sell Milestone Pharmaceuticals Inc. shares.

No Form 144 notices for Milestone Pharmaceuticals Inc. are on file.