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Milestone Pharmaceuticals Inc.

MIST
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001408443

No open-market purchases or sales by Milestone Pharmaceuticals Inc. insiders were filed in the last 90 days; 78 institutions reported holding it in 13F filings for Q2 2026, worth $66.4M in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Milestone Pharmaceuticals Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
43
0 vs. Q1 2025
Shares held
11.8M
−6.56K (−0.1%) vs. Q1 2025
Total value
$22.9M
+$13.5M (+142.3%) vs. Q1 2025
New holders
10
10 more added
Sold out
10
9 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MIST on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 43 institutions
Q1 2021: 34 institutionsQ2 2021: 28 institutionsQ3 2021: 27 institutionsQ4 2021: 28 institutionsQ1 2022: 28 institutionsQ2 2022: 29 institutionsQ3 2022: 47 institutionsQ4 2022: 56 institutionsQ1 2023: 50 institutionsQ2 2023: 48 institutionsQ3 2023: 39 institutionsQ4 2023: 40 institutionsQ1 2024: 43 institutionsQ2 2024: 40 institutionsQ3 2024: 43 institutionsQ4 2024: 47 institutionsQ1 2025: 43 institutionsQ2 2025: 43 institutionsQ3 2025: 61 institutionsQ4 2025: 80 institutionsQ1 2026: 87 institutionsQ2 2026: 78 institutions
Value heldQ2 2025: $22.9M
Q1 2021: $117.4MQ2 2021: $110.8MQ3 2021: $113.9MQ4 2021: $132.6MQ1 2022: $135.1MQ2 2022: $127.2MQ3 2022: $198.7MQ4 2022: $96.9MQ1 2023: $85.5MQ2 2023: $59.0MQ3 2023: $60.7MQ4 2023: $29.7MQ1 2024: $56.4MQ2 2024: $39.9MQ3 2024: $43.6MQ4 2024: $57.9MQ1 2025: $9.46MQ2 2025: $22.9MQ3 2025: $68.3MQ4 2025: $70.7MQ1 2026: $47.2MQ2 2026: $66.4M
Institutions holding MIST and their total value by quarter
QuarterHoldersValue
Q2 202678$66.4M
Q1 202687$47.2M
Q4 202580$70.7M
Q3 202561$68.3M
Q2 202543$22.9M
Q1 202543$9.46M
Q4 202447$57.9M
Q3 202443$43.6M
Q2 202440$39.9M
Q1 202443$56.4M
Q4 202340$29.7M
Q3 202339$60.7M
Q2 202348$59.0M
Q1 202350$85.5M
Q4 202256$96.9M
Q3 202247$198.7M
Q2 202229$127.2M
Q1 202228$135.1M
Q4 202128$132.6M
Q3 202127$113.9M
Q2 202128$110.8M
Q1 202134$117.4M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Milestone Pharmaceuticals Inc.; share changes are against Q1 2025.

Institutions holding MIST in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
RTW Investments, LP2,506,102$4.86M0.07%00.0%Unchanged
Propel Bio Management, LLC1,791,557$3.48M4.22%+340,000+23.4%Added
Alta Fundamental Advisers LLC1,398,977$2.71M1.48%−28,502−2.0%Reduced
BML Capital Management, LLC1,136,091$2.20M1.69%00.0%Unchanged
Simplify Asset Management Inc.990,000$1.92M0.12%+140,000+16.5%Added
Morgan Stanley820,421$1.59M0.00%−148,104−15.3%Reduced
Toronto Dominion Bank750,000$1.46M0.00%00.0%Unchanged
Lion Point Capital, LP548,806$1.06M7.23%00.0%Unchanged
Bleichroeder LP500,000$970.0K0.24%00.0%Unchanged
UBS Group AG322,648$625.9K0.00%+211,125+189.3%Added
XTX Topco Ltd160,963$312.3K0.01%+108,959+209.5%Added
Valeo Financial Advisors, LLC130,699$253.6K0.01%+110,699+553.5%Added
Goldman Sachs Group Inc119,449$231.7K0.00%+119,449New
Cascades Capital Asset Management, LLC67,135$130.2K0.07%+67,135New
Susquehanna International Group, LLP63,369$122.9K0.00%+1,309+2.1%Added
Northern Trust Corp53,001$102.8K0.00%00.0%Unchanged
Raymond James Financial Inc43,235$83.9K0.00%+10,000+30.1%Added
Colony Group, LLC36,000$69.8K0.00%+36,000New
Royal Bank of Canada35,600$69.0K0.00%+25,600+256.0%Added
Jane Street Group, LLC31,933$62.0K0.00%+31,933New
Group One Trading, L.P.31,616$61.3K0.00%−106,744−77.1%Reduced
Safeguard Investment Advisory Group, LLC25,044$48.6K0.01%00.0%Unchanged
Creative Planning23,410$45.4K0.00%+10,000+74.6%Added
Scientech Research LLC19,064$37.0K0.01%−3,854−16.8%Reduced
National Bank of Canada18,700$36.1K0.00%00.0%Unchanged
State Street Corp18,246$35.4K0.00%−291−1.6%Reduced
Geode Capital Management, LLC17,958$34.8K0.00%−1,914−9.6%Reduced
Walleye Capital LLC15,109$29.3K0.00%−76,811−83.6%Reduced
Mercer Global Advisors Inc15,100$29.3K0.00%+15,100New
Journey Strategic Wealth LLC15,000$29.1K0.00%00.0%Unchanged
Virtu Financial LLC14,761$29.0K0.00%+14,761New
Bay Rivers Group14,321$27.8K0.01%+14,321New
Beta Wealth Group, Inc.14,127$27.4K0.01%00.0%Unchanged
Federation des caisses Desjardins du Quebec13,000$25.2K0.00%00.0%Unchanged
LPL Financial LLC11,050$21.4K0.00%−100,490−90.1%Reduced
Mariner, LLC11,000$21.3K0.00%+11,000New
Jones Financial Companies LLLP11,000$20.5K0.00%00.0%Unchanged
Ancora Advisors, LLC10,000$19.4K0.00%00.0%Unchanged
Taylor Financial Group, Inc.10,000$19.4K0.01%+10,000New
US Bancorp3,200$6.21K0.00%00.0%Unchanged
Oliver Lagore Vanvalin Investment Group100$800.00%+100New
Bank of America Corp8$160.00%−39,388−100.0%Reduced
SBI Securities Co., Ltd.6$120.00%+2+50.0%Added
Millennium Management LLC0$00.00%−322,082−100.0%Sold out
Stonepine Capital Management, LLC0$00.00%−250,000−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−76,000−100.0%Sold out
Simplex Trading, LLC0$00.00%−40,636−100.0%Sold out
Dimensional Fund Advisors LP0$00.00%−39,450−100.0%Sold out
BNP Paribas Arbitrage, SA0$00.00%−26,023−100.0%Sold out
Clear Creek Financial Management, LLC0$00.00%−10,500−100.0%Sold out
Integrated Wealth Concepts LLC0$00.00%−10,000−100.0%Sold out
JPMorgan Chase & Co0$00.00%−3,266−100.0%Sold out
Citigroup Inc0$00.00%−2−100.0%Sold out