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Milestone Pharmaceuticals Inc.

MIST
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001408443

No open-market purchases or sales by Milestone Pharmaceuticals Inc. insiders were filed in the last 90 days; 78 institutions reported holding it in 13F filings for Q2 2026, worth $66.4M in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Milestone Pharmaceuticals Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
47
+4 vs. Q3 2024
Shares held
24.6M
−4.13M (−14.4%) vs. Q3 2024
Total value
$57.9M
+$14.4M (+32.9%) vs. Q3 2024
New holders
10
14 more added
Sold out
6
14 more reduced

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MIST on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 47 institutions
Q1 2021: 34 institutionsQ2 2021: 28 institutionsQ3 2021: 27 institutionsQ4 2021: 28 institutionsQ1 2022: 28 institutionsQ2 2022: 29 institutionsQ3 2022: 47 institutionsQ4 2022: 56 institutionsQ1 2023: 50 institutionsQ2 2023: 48 institutionsQ3 2023: 39 institutionsQ4 2023: 40 institutionsQ1 2024: 43 institutionsQ2 2024: 40 institutionsQ3 2024: 43 institutionsQ4 2024: 47 institutionsQ1 2025: 43 institutionsQ2 2025: 43 institutionsQ3 2025: 61 institutionsQ4 2025: 80 institutionsQ1 2026: 87 institutionsQ2 2026: 78 institutions
Value heldQ4 2024: $57.9M
Q1 2021: $117.4MQ2 2021: $110.8MQ3 2021: $113.9MQ4 2021: $132.6MQ1 2022: $135.1MQ2 2022: $127.2MQ3 2022: $198.7MQ4 2022: $96.9MQ1 2023: $85.5MQ2 2023: $59.0MQ3 2023: $60.7MQ4 2023: $29.7MQ1 2024: $56.4MQ2 2024: $39.9MQ3 2024: $43.6MQ4 2024: $57.9MQ1 2025: $9.46MQ2 2025: $22.9MQ3 2025: $68.3MQ4 2025: $70.7MQ1 2026: $47.2MQ2 2026: $66.4M
Institutions holding MIST and their total value by quarter
QuarterHoldersValue
Q2 202678$66.4M
Q1 202687$47.2M
Q4 202580$70.7M
Q3 202561$68.3M
Q2 202543$22.9M
Q1 202543$9.46M
Q4 202447$57.9M
Q3 202443$43.6M
Q2 202440$39.9M
Q1 202443$56.4M
Q4 202340$29.7M
Q3 202339$60.7M
Q2 202348$59.0M
Q1 202350$85.5M
Q4 202256$96.9M
Q3 202247$198.7M
Q2 202229$127.2M
Q1 202228$135.1M
Q4 202128$132.6M
Q3 202127$113.9M
Q2 202128$110.8M
Q1 202134$117.4M

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Milestone Pharmaceuticals Inc.; share changes are against Q3 2024.

Institutions holding MIST in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock, Inc.4,050,686$9.56M0.00%−920,658−18.5%Reduced
Millennium Management LLC2,703,259$6.38M0.01%−75,266−2.7%Reduced
Alta Fundamental Advisers LLC2,658,589$6.27M2.32%00.0%Unchanged
RTW Investments, LP2,506,102$5.91M0.09%−750,000−23.0%Reduced
OrbiMed Advisors LLC2,000,000$4.72M0.10%00.0%Unchanged
Nantahala Capital Management, LLC1,445,264$3.41M0.24%−304,736−17.4%Reduced
Bleichroeder LP1,326,085$3.13M0.79%00.0%Unchanged
Morgan Stanley1,289,141$3.04M0.00%+370,829+40.4%Added
BML Capital Management, LLC1,136,091$2.68M1.67%00.0%Unchanged
Lion Point Capital, LP1,025,806$2.42M12.68%−628,348−38.0%Reduced
Goldman Sachs Group Inc942,407$2.22M0.00%−410,660−30.4%Reduced
Toronto Dominion Bank750,000$1.77M0.00%+750,000New
Citadel Advisors LLC608,202$1.44M0.00%−1,453,320−70.5%Reduced
Stonepine Capital Management, LLC500,000$1.18M0.95%−499,790−50.0%Reduced
Ikarian Capital, LLC466,030$1.10M0.31%+110.0%Added
Boxer Capital Management, LLC309,007$729.3K0.06%+309,007New
UBS Group AG89,506$211.2K0.00%+89,506New
Virtu Financial LLC71,955$170.0K0.01%+71,955New
Envestnet Asset Management Inc63,742$150.4K0.00%−6,848−9.7%Reduced
Northern Trust Corp58,108$137.1K0.00%+30,772+112.6%Added
Squarepoint Ops LLC56,751$133.9K0.00%+2,506+4.6%Added
Group One Trading, L.P.52,637$124.2K0.00%+52,637New
Dimensional Fund Advisors LP39,450$92.9K0.00%00.0%Unchanged
Atria Investments LLC38,666$91.3K0.00%−1,755−4.3%Reduced
XTX Topco Ltd34,054$80.4K0.01%+34,054New
Susquehanna International Group, LLP33,092$78.1K0.00%+33,092New
BNP Paribas Arbitrage, SA31,133$73.5K0.00%+1,924+6.6%Added
Cubist Systematic Strategies, LLC30,938$73.0K0.00%+30,938New
Boothbay Fund Management, LLC30,790$72.7K0.00%+110.0%Added
Cetera Investment Advisers24,731$58.4K0.00%+60+0.2%Added
Valeo Financial Advisors, LLC20,000$47.2K0.00%00.0%Unchanged
Geode Capital Management, LLC19,872$46.9K0.00%+2,296+13.1%Added
State Street Corp19,117$45.1K0.00%−194−1.0%Reduced
National Bank of Canada18,700$44.1K0.00%+11,600+163.4%Added
Two Sigma Securities, LLC16,957$40.0K0.01%−6,176−26.7%Reduced
Creative Planning14,180$33.5K0.00%+1,100+8.4%Added
Beta Wealth Group, Inc.14,127$33.3K0.01%00.0%Unchanged
Federation des caisses Desjardins du Quebec13,000$30.7K0.00%+2,500+23.8%Added
Jones Financial Companies LLLP11,000$26.0K0.00%+10,000+1,000.0%Added
Clear Creek Financial Management, LLC10,500$24.8K0.00%−9,000−46.2%Reduced
Ancora Advisors, LLC10,000$23.6K0.00%−50,000−83.3%Reduced
Advisor Group Holdings, Inc.6,934$16.4K0.00%+434+6.7%Added
Simplex Trading, LLC4,642$10.0K0.00%+4,428+2,069.2%Added
JPMorgan Chase & Co900$2.12K0.00%+900New
Citigroup Inc329$7760.00%+329New
Barclays PLC100$2360.00%00.0%Unchanged
Oliver Lagore Vanvalin Investment Group100$2360.00%00.0%Unchanged
Altium Capital Management LP0$00.00%−440,000−100.0%Sold out
Boxer Capital, LLC0$00.00%−309,007−100.0%Sold out
PVG Asset Management Corp0$00.00%−30,345−100.0%Sold out
ADAR1 Capital Management, LLC0$00.00%−27,931−100.0%Sold out
Engineers Gate Manager LP0$00.00%−11,074−100.0%Sold out
Royal Bank of Canada0$00.00%−800−100.0%Sold out