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Milestone Pharmaceuticals Inc.

MIST
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001408443

No open-market purchases or sales by Milestone Pharmaceuticals Inc. insiders were filed in the last 90 days; 78 institutions reported holding it in 13F filings for Q2 2026, worth $66.4M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Milestone Pharmaceuticals Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
87
+7 vs. Q4 2025
Shares held
39.5M
+4.53M (+13.0%) vs. Q4 2025
Total value
$47.2M
−$23.5M (−33.2%) vs. Q4 2025
New holders
21
23 more added
Sold out
14
19 more reduced

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MIST on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 87 institutions
Q1 2021: 34 institutionsQ2 2021: 28 institutionsQ3 2021: 27 institutionsQ4 2021: 28 institutionsQ1 2022: 28 institutionsQ2 2022: 29 institutionsQ3 2022: 47 institutionsQ4 2022: 56 institutionsQ1 2023: 50 institutionsQ2 2023: 48 institutionsQ3 2023: 39 institutionsQ4 2023: 40 institutionsQ1 2024: 43 institutionsQ2 2024: 40 institutionsQ3 2024: 43 institutionsQ4 2024: 47 institutionsQ1 2025: 43 institutionsQ2 2025: 43 institutionsQ3 2025: 61 institutionsQ4 2025: 80 institutionsQ1 2026: 87 institutionsQ2 2026: 78 institutions
Value heldQ1 2026: $47.2M
Q1 2021: $117.4MQ2 2021: $110.8MQ3 2021: $113.9MQ4 2021: $132.6MQ1 2022: $135.1MQ2 2022: $127.2MQ3 2022: $198.7MQ4 2022: $96.9MQ1 2023: $85.5MQ2 2023: $59.0MQ3 2023: $60.7MQ4 2023: $29.7MQ1 2024: $56.4MQ2 2024: $39.9MQ3 2024: $43.6MQ4 2024: $57.9MQ1 2025: $9.46MQ2 2025: $22.9MQ3 2025: $68.3MQ4 2025: $70.7MQ1 2026: $47.2MQ2 2026: $66.4M
Institutions holding MIST and their total value by quarter
QuarterHoldersValue
Q2 202678$66.4M
Q1 202687$47.2M
Q4 202580$70.7M
Q3 202561$68.3M
Q2 202543$22.9M
Q1 202543$9.46M
Q4 202447$57.9M
Q3 202443$43.6M
Q2 202440$39.9M
Q1 202443$56.4M
Q4 202340$29.7M
Q3 202339$60.7M
Q2 202348$59.0M
Q1 202350$85.5M
Q4 202256$96.9M
Q3 202247$198.7M
Q2 202229$127.2M
Q1 202228$135.1M
Q4 202128$132.6M
Q3 202127$113.9M
Q2 202128$110.8M
Q1 202134$117.4M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Milestone Pharmaceuticals Inc.; share changes are against Q4 2025.

Institutions holding MIST in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
SBI Securities Co., Ltd.11$130.00%+5+83.3%Added
Russell Investments Group, Ltd.125$1490.00%+125New
Key Capital Management, INC212$2520.00%00.0%Unchanged
Rialto Wealth Management, LLC300$3570.00%00.0%Unchanged
Medallion Wealth Advisors, LLC340$4050.00%00.0%Unchanged
The PNC Financial Services Group, Inc.1,000$1.19K0.00%+1,000New
Caitong International Asset Management Co., Ltd1,729$2.06K0.00%+1,729New
US Bancorp3,200$3.81K0.00%00.0%Unchanged
Royal Bank of Canada6,698$8.00K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)9,147$10.9K0.00%+167+1.9%Added
Ancora Advisors, LLC10,000$11.9K0.00%00.0%Unchanged
Secure Asset Management, LLC10,000$11.9K0.00%00.0%Unchanged
Integral Investment Advisors, Inc.10,000$11.9K0.00%00.0%Unchanged
HighTower Advisors, LLC10,000$11.9K0.00%+10,000New
CWM, LLC10,000$11.9K0.00%+10,000New
Bayesian Capital Management, LP10,015$11.9K0.01%−7,200−41.8%Reduced
Eaton Financial Holdings Company, LLC10,250$12.2K0.00%−2,500−19.6%Reduced
Bronte Capital Management Pty Ltd.10,414$12.4K0.00%00.0%Unchanged
Wealthspire Advisors, LLC10,629$12.6K0.00%+10,629New
IMC-Chicago, LLC10,943$13.0K0.00%+10,943New
Rockefeller Capital Management L.P.12,500$14.9K0.00%+10,800+635.3%Added
Creative Planning13,410$16.0K0.00%−10,000−42.7%Reduced
Strategic Family Wealth Counselors, L.L.C.13,875$16.5K0.00%+1,200+9.5%Added
Jones Financial Companies LLLP16,000$16.6K0.00%00.0%Unchanged
Beta Wealth Group, Inc.14,127$16.8K0.01%00.0%Unchanged
Cetera Investment Advisers14,704$17.5K0.00%−6,018−29.0%Reduced
Capital Performance Advisors LLP14,756$17.6K0.00%+14,756New
SJS Investment Consulting Inc.15,000$17.9K0.00%00.0%Unchanged
Taylor Financial Group, Inc.15,000$17.9K0.01%+5,000+50.0%Added
AE Wealth Management LLC15,000$17.9K0.00%+15,000New
Vision Retirement, LLC15,000$17.9K0.01%+15,000New
Exit Wealth Advisors, LLC.15,000$17.9K0.01%+15,000New
Pathstone Holdings, LLC17,040$20.3K0.00%−1,000,000−98.3%Reduced
Journey Strategic Wealth LLC20,000$23.8K0.00%00.0%Unchanged
Stephenson & Company, Inc.20,000$23.8K0.01%00.0%Unchanged
Acadian Asset Management LLC20,468$24.0K0.00%−155,732−88.4%Reduced
State Street Corp22,331$26.6K0.00%+456+2.1%Added
National Bank of Canada23,500$28.0K0.00%+4,800+25.7%Added
Welch & Forbes LLC25,000$29.8K0.00%+25,000New
Safeguard Investment Advisory Group, LLC25,044$29.8K0.01%00.0%Unchanged
Raymond James Financial Inc26,600$31.7K0.00%00.0%Unchanged
Gsa Capital Partners LLP26,893$32.0K0.00%−209,245−88.6%Reduced
Federation des caisses Desjardins du Quebec29,781$35.4K0.00%00.0%Unchanged
Bay Rivers Group29,911$35.6K0.01%+1,050+3.6%Added
Mariner, LLC30,830$36.7K0.00%+5,830+23.3%Added
Colony Group, LLC36,000$42.8K0.00%00.0%Unchanged
Northern Trust Corp38,779$46.1K0.00%−479−1.2%Reduced
Geode Capital Management, LLC40,789$48.5K0.00%−33,233−44.9%Reduced
Invesco Ltd.41,356$49.2K0.00%+19,463+88.9%Added
SG Americas Securities, LLC42,512$51.0K0.00%−54,863−56.3%Reduced
October Effect Ltd51,950$61.8K0.07%−150−0.3%Reduced
Cambridge Investment Research Advisors, Inc.59,620$71.0K0.00%+12,480+26.5%Added
HRT Financial LP62,256$74.0K0.00%+62,256New
ADAR1 Capital Management, LLC100,000$119.0K0.01%−100−0.1%Reduced
Tru Independence Asset Management 2, LLC100,000$119.0K0.07%00.0%Unchanged
XTX Topco Ltd120,602$143.5K0.00%−51,358−29.9%Reduced
Renaissance Technologies LLC129,705$154.3K0.00%+129,705New
Group One Trading, L.P.129,764$154.4K0.01%−65,335−33.5%Reduced
Valeo Financial Advisors, LLC130,699$155.5K0.00%00.0%Unchanged
Quadrature Capital Ltd149,105$177.4K0.00%+149,105New
Simplex Trading, LLC149,291$177.7K0.01%+149,291New
Jane Street Group, LLC159,669$190.0K0.00%−933,561−85.4%Reduced
Boothbay Fund Management, LLC168,675$200.7K0.00%+168,675New
BNP Paribas Arbitrage, SA176,504$210.0K0.00%−45,447−20.5%Reduced
LPL Financial LLC193,373$230.1K0.00%+50,910+35.7%Added
Citadel Advisors LLC196,696$234.1K0.00%−156,536−44.3%Reduced
Aptus Capital Advisors, LLC280,250$333.5K0.00%+17,050+6.5%Added
Guardian Wealth Advisors, LLC280,250$333.5K0.02%+17,050+6.5%Added
Seven Fleet Capital Management LP333,333$396.7K0.12%+333,333New
Squarepoint Ops LLC336,825$400.8K0.00%+87,481+35.1%Added
UBS Group AG494,908$588.9K0.00%+3,040+0.6%Added
Susquehanna International Group, LLP519,046$617.7K0.00%−124,254−19.3%Reduced
Boxer Capital Management, LLC666,666$793.3K0.10%00.0%Unchanged
Ameriprise Financial Inc666,666$793.3K0.00%+666,666New
Morgan Stanley724,141$861.7K0.00%−57,734−7.4%Reduced
Toronto Dominion Bank750,000$892.5K0.00%00.0%Unchanged
Lion Point Capital, LP820,000$975.8K5.83%+65,000+8.6%Added
Balyasny Asset Management LLC851,325$1.01M0.00%+851,325New
Point72 Asset Management, L.P.1,085,683$1.29M0.00%+603,328+125.1%Added
Simplify Asset Management Inc.1,506,405$1.79M0.03%00.0%Unchanged
Millennium Management LLC1,544,325$1.84M0.00%+1,141,690+283.6%Added
Marshall Wace, LLP1,944,530$2.31M0.00%+287,709+17.4%Added
Goldman Sachs Group Inc2,000,025$2.38M0.00%+2,000,025New
Two Sigma Investments, LP2,317,176$2.76M0.00%+802,715+53.0%Added
Propel Bio Management, LLC4,118,321$5.08M3.20%00.0%Unchanged
RTW Investments, LP6,331,001$7.53M0.07%+3,824,899+152.6%Added
Pavaki Capital Management LLC9,062,848$10.8M7.58%+563,933+6.6%Added
Adage Capital Partners GP, L.L.C.0$00.00%−2,810,037−100.0%Sold out
Stonepine Capital Management, LLC0$00.00%−662,666−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−619,592−100.0%Sold out
Nomura Holdings Inc0$00.00%−225,000−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−133,620−100.0%Sold out
Cascades Capital Asset Management, LLC0$00.00%−77,510−100.0%Sold out
Engineers Gate Manager LP0$00.00%−59,053−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−34,596−100.0%Sold out
Citigroup Inc0$00.00%−33,858−100.0%Sold out
Scientech Research LLC0$00.00%−30,124−100.0%Sold out
Quantbot Technologies LP0$00.00%−18,990−100.0%Sold out
AQR Capital Management LLC0$00.00%−10,000−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−1,591−100.0%Sold out