Maze Therapeutics, Inc.
MAZE- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001842295
In the last 90 days, Maze Therapeutics, Inc. insiders filed 0 open-market purchases and 14 sales; 161 institutions reported holding it in 13F filings for Q2 2026, worth $1.75B in total; HHLR Advisors (Hillhouse) is the only superinvestor holding it.
13F holders, Q4 2025
Institutional positions in Maze Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 143
- +49 vs. Q3 2025
- Shares held
- 48.4M
- +5.40M (+12.6%) vs. Q3 2025
- Total value
- $2.00B
- +$889.5M (+79.8%) vs. Q3 2025
- New holders
- 57
- 46 more added
- Sold out
- 8
- 20 more reduced
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting MAZE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 161 | $1.75B |
| Q1 2026 | 165 | $1.54B |
| Q4 2025 | 143 | $2.00B |
| Q3 2025 | 94 | $1.11B |
| Q2 2025 | 75 | $476.7M |
| Q1 2025 | 68 | $441.4M |
| Q4 2024 | 0 | $0 |
| Q3 2024 | 0 | $0 |
| Q2 2024 | 0 | $0 |
| Q1 2024 | 0 | $0 |
| Q4 2023 | 0 | $0 |
| Q3 2023 | 0 | $0 |
| Q2 2023 | 0 | $0 |
| Q1 2023 | 0 | $0 |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Maze Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | 4,567,274 | $189.2M | 5.08% | 00.0% | Unchanged |
| TRV GP IV, LLC | 4,473,958 | $185.4M | 72.65% | −1,600,000−26.3% | Reduced |
| Deep Track Capital, LP | 4,246,440 | $175.9M | 4.01% | +297,530+7.5% | Added |
| ARCH Venture Management, LLC | 4,120,053 | $170.7M | 26.19% | 00.0% | Unchanged |
| Janus Henderson Group PLC | 3,142,587 | $130.2M | 0.06% | +2,390,713+318.0% | Added |
| BlackRock, Inc. | 2,287,155 | $94.8M | 0.00% | +971,139+73.8% | Added |
| AH Capital Management, L.L.C. | 1,702,225 | $70.5M | 4.46% | 00.0% | Unchanged |
| Vanguard Group Inc | 1,697,015 | $70.3M | 0.00% | +362,060+27.1% | Added |
| VR Adviser, LLC | 1,548,569 | $64.2M | 3.17% | +317,800+25.8% | Added |
| Alphabet Inc. | 1,388,583 | $57.5M | 2.23% | −1,023,888−42.4% | Reduced |
| General Catalyst Group Management, LLC | 1,035,910 | $42.9M | 19.35% | 00.0% | Unchanged |
| Woodline Partners LP | 1,035,229 | $42.9M | 0.17% | 00.0% | Unchanged |
| TRV GP V, LLC | 950,800 | $39.4M | 9.18% | 00.0% | Unchanged |
| Logos Global Management LP | 950,000 | $39.4M | 2.62% | −277,300−22.6% | Reduced |
| Bellevue Group AG | 887,708 | $36.8M | 0.70% | +887,708 | New |
| Marshall Wace, LLP | 847,472 | $35.1M | 0.03% | +69,771+9.0% | Added |
| ArrowMark Colorado Holdings LLC | 767,383 | $31.8M | 0.70% | +222,251+40.8% | Added |
| Casdin Capital, LLC | 758,857 | $31.4M | 1.95% | 00.0% | Unchanged |
| FMR LLC | 728,605 | $30.2M | 0.00% | +72,991+11.1% | Added |
| Ikarian Capital, LLC | 644,680 | $26.7M | 3.46% | −96,145−13.0% | Reduced |
| Caligan Partners LP | 550,191 | $22.8M | 2.09% | +550,191 | New |
| State Street Corp | 533,005 | $22.1M | 0.00% | +148,303+38.6% | Added |
| Geode Capital Management, LLC | 527,281 | $21.9M | 0.00% | +53,732+11.3% | Added |
| Foresite Capital Management IV, LLC | 522,657 | $21.7M | 9.43% | 00.0% | Unchanged |
| Squadron Capital Management LLC | 490,000 | $20.3M | 9.06% | +490,000 | New |
| Bessemer Group Inc | 481,790 | $20.0M | 0.03% | 00.0% | Unchanged |
| Matrix Capital Management Company, LP | 480,000 | $19.9M | 34.52% | −1,173,684−71.0% | Reduced |
| HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse) | 457,535 | $19.0M | 0.61% | 00.0% | Unchanged |
| Citadel Advisors LLC | 448,217 | $18.6M | 0.01% | +448,217 | New |
| Boothbay Fund Management, LLC | 409,372 | $17.0M | 0.45% | +57,497+16.3% | Added |
| Driehaus Capital Management LLC | 378,015 | $15.7M | 0.11% | 00.0% | Unchanged |
| Eventide Asset Management, LLC | 324,041 | $13.4M | 0.21% | +324,041 | New |
| Washington University | 280,802 | $11.6M | 5.88% | +70,121+33.3% | Added |
| Morgan Stanley | 258,086 | $10.7M | 0.00% | +45,324+21.3% | Added |
| Mass General Brigham, Inc | 239,994 | $9.94M | 1.23% | +239,994 | New |
| Parkman Healthcare Partners LLC | 209,266 | $8.67M | 0.83% | +9,266+4.6% | Added |
| Balyasny Asset Management LLC | 199,212 | $8.25M | 0.02% | −234,513−54.1% | Reduced |
| Alyeska Investment Group, L.P. | 196,124 | $8.13M | 0.02% | +71,124+56.9% | Added |
| Ensign Peak Advisors, Inc | 185,794 | $7.70M | 0.01% | +115,129+162.9% | Added |
| ADAR1 Capital Management, LLC | 179,532 | $7.44M | 0.56% | +153,487+589.3% | Added |
| Northern Trust Corp | 176,259 | $7.30M | 0.00% | −631−0.4% | Reduced |
| Charles Schwab Investment Management Inc | 175,969 | $7.29M | 0.00% | +8,041+4.8% | Added |
| TCG Crossover Management, LLC | 173,816 | $7.20M | 0.24% | +173,816 | New |
| HighVista Strategies LLC | 170,353 | $7.06M | 1.82% | +170,353 | New |
| Millennium Management LLC | 154,470 | $6.40M | 0.00% | +154,470 | New |
| Invesco Ltd. | 134,033 | $5.55M | 0.00% | +1,971+1.5% | Added |
| StemPoint Capital LP | 125,877 | $5.22M | 0.89% | +125,877 | New |
| Freestone Grove Partners LP | 118,876 | $4.93M | 0.04% | +118,876 | New |
| Price T Rowe Associates Inc | 115,711 | $4.79M | 0.00% | +105,237+1,004.7% | Added |
| Goldman Sachs Group Inc | 114,455 | $4.74M | 0.00% | +114,455 | New |
| Integral Health Asset Management, LLC | 100,000 | $4.14M | 0.21% | +100,000 | New |
| Ameriprise Financial Inc | 96,688 | $4.01M | 0.00% | +96,688 | New |
| Foresite Capital Management V, LLC | 86,291 | $3.58M | 2.17% | 00.0% | Unchanged |
| MPM Oncology Impact Management LP | 81,145 | $3.36M | 0.38% | +81,145 | New |
| Sphera Funds Management Ltd. | 71,843 | $2.98M | 0.62% | −82,500−53.5% | Reduced |
| SummitTX Capital, L.P. | 69,560 | $2.88M | 0.09% | +69,560 | New |
| Raymond James Financial Inc | 67,718 | $2.81M | 0.00% | +67,718 | New |
| Wellington Management Group LLP | 61,205 | $2.54M | 0.00% | +61,205 | New |
| Bank of New York Mellon Corp | 60,436 | $2.50M | 0.00% | +15,196+33.6% | Added |
| Advisor Group Holdings, Inc. | 59,762 | $2.48M | 0.00% | +29,237+95.8% | Added |
| Nuveen, LLC | 57,258 | $2.37M | 0.00% | +26,954+88.9% | Added |
| Franklin Resources Inc | 55,229 | $2.29M | 0.00% | +37,031+203.5% | Added |
| Trexquant Investment LP | 52,459 | $2.17M | 0.02% | +52,459 | New |
| Seven Grand Managers, LLC | 50,000 | $2.07M | 0.16% | +50,000 | New |
| Schonfeld Strategic Advisors LLC | 48,200 | $2.00M | 0.01% | −65,849−57.7% | Reduced |
| Barclays PLC | 39,508 | $1.64M | 0.00% | +11,992+43.6% | Added |
| D. E. Shaw & Co., Inc. | 33,694 | $1.40M | 0.00% | +33,694 | New |
| Alliancebernstein L.P. | 33,220 | $1.38M | 0.00% | −26,880−44.7% | Reduced |
| XTX Topco Ltd | 33,021 | $1.37M | 0.04% | +6,154+22.9% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 31,295 | $1.30M | 0.00% | +22,217+244.7% | Added |
| Cinctive Capital Management LP | 29,134 | $1.21M | 0.07% | +29,134 | New |
| UBS Group AG | 28,698 | $1.19M | 0.00% | +905+3.3% | Added |
| AQR Capital Management LLC | 27,439 | $1.14M | 0.00% | −176−0.6% | Reduced |
| Renaissance Technologies LLC | 27,100 | $1.12M | 0.00% | −59,000−68.5% | Reduced |
| Tudor Investment Corp Et Al | 24,059 | $996.8K | 0.01% | +24,059 | New |
| Wells Fargo & Company | 24,008 | $994.7K | 0.00% | +9,229+62.4% | Added |
| Rhumbline Advisers | 23,731 | $983.2K | 0.00% | +2,761+13.2% | Added |
| Gilder Gagnon Howe & Co LLC | 23,282 | $964.6K | 0.01% | +23,282 | New |
| Russell Investments Group, Ltd. | 22,545 | $934.0K | 0.00% | +20,638+1,082.2% | Added |
| Verition Fund Management LLC | 22,512 | $932.7K | 0.01% | +22,512 | New |
| American Century Companies Inc | 21,509 | $891.1K | 0.00% | +21,509 | New |
| JPMorgan Chase & Co | 20,007 | $828.9K | 0.00% | +12,117+153.6% | Added |
| Acuta Capital Partners, LLC | 20,000 | $828.6K | 0.56% | +20,000 | New |
| Bank of America Corp | 18,381 | $761.5K | 0.00% | +8,807+92.0% | Added |
| Deutsche Bank AG | 15,522 | $643.1K | 0.00% | +6,637+74.7% | Added |
| Los Angeles Capital Management LLC | 19,100 | $634.5K | 0.00% | +19,100 | New |
| Two Sigma Advisers, LP | 14,800 | $613.2K | 0.00% | +14,800 | New |
| PSP Research LLC | 12,672 | $525.0K | 0.46% | +12,672 | New |
| MetLife Investment Management | 11,801 | $488.9K | 0.00% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 11,441 | $474.0K | 0.04% | +9,441+472.1% | Added |
| Citigroup Inc | 11,252 | $466.2K | 0.00% | +10,983+4,082.9% | Added |
| STRS Ohio | 11,200 | $464.0K | 0.00% | −6,700−37.4% | Reduced |
| Falcon Wealth Planning | 10,030 | $415.5K | 0.03% | +10,030 | New |
| SG Americas Securities, LLC | 8,493 | $352.0K | 0.00% | +3,478+69.4% | Added |
| Two Sigma Investments, LP | 7,245 | $300.2K | 0.00% | −3,905−35.0% | Reduced |
| Manufacturers Life Insurance Company, The | 6,897 | $285.7K | 0.00% | +6,897 | New |
| Virtus Investment Advisers, Inc. | 6,846 | $283.6K | 0.08% | −1,551−18.5% | Reduced |
| New York State Common Retirement Fund | 6,700 | $277.6K | 0.00% | 00.0% | Unchanged |
| Persistent Asset Partners Ltd | 6,605 | $273.6K | 0.13% | +6,605 | New |
| Intech Investment Management LLC | 6,443 | $266.9K | 0.00% | +6,443 | New |