Maze Therapeutics, Inc.
MAZE- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001842295
In the last 90 days, Maze Therapeutics, Inc. insiders filed 0 open-market purchases and 14 sales; 161 institutions reported holding it in 13F filings for Q2 2026, worth $1.75B in total; HHLR Advisors (Hillhouse) is the only superinvestor holding it.
13F holders, Q3 2025
Institutional positions in Maze Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 94
- +20 vs. Q2 2025
- Shares held
- 43.0M
- +4.16M (+10.7%) vs. Q2 2025
- Total value
- $1.11B
- +$637.9M (+133.9%) vs. Q2 2025
- New holders
- 23
- 39 more added
- Sold out
- 3
- 15 more reduced
1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting MAZE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 161 | $1.75B |
| Q1 2026 | 165 | $1.54B |
| Q4 2025 | 143 | $2.00B |
| Q3 2025 | 94 | $1.11B |
| Q2 2025 | 75 | $476.7M |
| Q1 2025 | 68 | $441.4M |
| Q4 2024 | 0 | $0 |
| Q3 2024 | 0 | $0 |
| Q2 2024 | 0 | $0 |
| Q1 2024 | 0 | $0 |
| Q4 2023 | 0 | $0 |
| Q3 2023 | 0 | $0 |
| Q2 2023 | 0 | $0 |
| Q1 2023 | 0 | $0 |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Maze Therapeutics, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| TRV GP IV, LLC | 6,073,958 | $157.5M | 57.49% | 00.0% | Unchanged |
| Frazier Life Sciences Management, L.P. | 4,567,274 | $118.4M | 3.55% | −10.0% | Reduced |
| ARCH Venture Management, LLC | 4,120,053 | $106.8M | 21.70% | 00.0% | Unchanged |
| Deep Track Capital, LP | 3,948,910 | $102.4M | 2.86% | 00.0% | Unchanged |
| Alphabet Inc. | 2,412,471 | $62.6M | 2.60% | 00.0% | Unchanged |
| AH Capital Management, L.L.C. | 1,702,225 | $44.1M | 3.16% | 00.0% | Unchanged |
| Matrix Capital Management Company, LP | 1,653,684 | $42.9M | 40.17% | −832,500−33.5% | Reduced |
| Vanguard Group Inc | 1,334,955 | $34.6M | 0.00% | +915,342+218.1% | Added |
| BlackRock, Inc. | 1,316,016 | $34.1M | 0.00% | +701,312+114.1% | Added |
| VR Adviser, LLC | 1,230,769 | $31.9M | 1.80% | +1,230,769 | New |
| Logos Global Management LP | 1,227,300 | $31.8M | 3.14% | +615,386+100.6% | Added |
| General Catalyst Group Management, LLC | 1,035,910 | $26.9M | 0.88% | 00.0% | Unchanged |
| Woodline Partners LP | 1,035,229 | $26.8M | 0.13% | +94,529+10.0% | Added |
| TRV GP V, LLC | 950,800 | $24.7M | 6.97% | 00.0% | Unchanged |
| Marshall Wace, LLP | 777,701 | $20.2M | 0.02% | +758,104+3,868.5% | Added |
| Casdin Capital, LLC | 758,857 | $19.7M | 1.64% | 00.0% | Unchanged |
| Janus Henderson Group PLC | 751,874 | $19.5M | 0.01% | −649,386−46.3% | Reduced |
| Ikarian Capital, LLC | 740,825 | $19.2M | 4.35% | +478,085+182.0% | Added |
| FMR LLC | 655,614 | $17.0M | 0.00% | +101,080+18.2% | Added |
| ArrowMark Colorado Holdings LLC | 545,132 | $14.1M | 0.26% | +545,132 | New |
| Foresite Capital Management IV, LLC | 522,657 | $13.6M | 7.42% | −1,589,262−75.3% | Reduced |
| Bessemer Group Inc | 481,790 | $12.5M | 0.02% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 473,549 | $12.3M | 0.00% | +242,312+104.8% | Added |
| HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse) | 457,535 | $11.9M | 0.29% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 433,725 | $11.2M | 0.02% | +433,725 | New |
| State Street Corp | 384,702 | $9.98M | 0.00% | +240,017+165.9% | Added |
| Driehaus Capital Management LLC | 378,015 | $9.80M | 0.07% | +184,615+95.5% | Added |
| Boothbay Fund Management, LLC | 351,875 | $9.12M | 0.24% | +276,345+365.9% | Added |
| Morgan Stanley | 212,762 | $5.52M | 0.00% | +180,981+569.5% | Added |
| Washington University | 210,681 | $5.46M | 3.06% | +210,681 | New |
| Parkman Healthcare Partners LLC | 200,000 | $5.19M | 0.57% | +200,000 | New |
| Octagon Capital Advisors LP | 177,667 | $4.61M | 0.72% | 00.0% | Unchanged |
| Northern Trust Corp | 176,890 | $4.59M | 0.00% | +91,344+106.8% | Added |
| Charles Schwab Investment Management Inc | 167,928 | $4.35M | 0.00% | +92,757+123.4% | Added |
| Sphera Funds Management Ltd. | 154,343 | $4.00M | 0.95% | −202,110−56.7% | Reduced |
| Invesco Ltd. | 132,062 | $3.42M | 0.00% | +113,632+616.6% | Added |
| Alyeska Investment Group, L.P. | 125,000 | $3.24M | 0.01% | 00.0% | Unchanged |
| Schonfeld Strategic Advisors LLC | 114,049 | $2.96M | 0.02% | +114,049 | New |
| Nantahala Capital Management, LLC | 93,351 | $2.42M | 0.15% | +93,351 | New |
| Harvard Management Co Inc | 92,396 | $2.40M | 0.11% | −545,132−85.5% | Reduced |
| Foresite Capital Management V, LLC | 86,291 | $2.24M | 2.06% | −258,900−75.0% | Reduced |
| Renaissance Technologies LLC | 86,100 | $2.23M | 0.00% | +86,100 | New |
| Ensign Peak Advisors, Inc | 70,665 | $1.83M | 0.00% | +52,126+281.2% | Added |
| Alliancebernstein L.P. | 60,100 | $1.56M | 0.00% | +28,304+89.0% | Added |
| Bank of New York Mellon Corp | 45,240 | $1.17M | 0.00% | +23,694+110.0% | Added |
| Advisor Group Holdings, Inc. | 30,525 | $791.5K | 0.00% | +30,471+56,427.8% | Added |
| Nuveen, LLC | 30,304 | $785.8K | 0.00% | +18,929+166.4% | Added |
| UBS Group AG | 27,793 | $720.7K | 0.00% | −23,609−45.9% | Reduced |
| AQR Capital Management LLC | 27,615 | $716.1K | 0.00% | +148+0.5% | Added |
| Barclays PLC | 27,516 | $713.5K | 0.00% | +12,875+87.9% | Added |
| XTX Topco Ltd | 26,867 | $696.7K | 0.04% | +26,867 | New |
| ADAR1 Capital Management, LLC | 26,045 | $675.3K | 0.07% | +26,045 | New |
| Rhumbline Advisers | 20,970 | $543.7K | 0.00% | +13,256+171.8% | Added |
| Franklin Resources Inc | 18,198 | $471.9K | 0.00% | +18,198 | New |
| STRS Ohio | 17,900 | $464.1K | 0.00% | −29,000−61.8% | Reduced |
| Susquehanna International Group, LLP | 16,165 | $419.2K | 0.00% | +5,598+53.0% | Added |
| Wells Fargo & Company | 14,779 | $383.2K | 0.00% | +9,164+163.2% | Added |
| Winton Group Ltd | 14,487 | $375.6K | 0.01% | +14,487 | New |
| Alps Advisors Inc | 13,742 | $356.3K | 0.00% | −9,835−41.7% | Reduced |
| BNP Paribas Arbitrage, SA | 12,018 | $311.6K | 0.00% | +11,259+1,483.4% | Added |
| MetLife Investment Management | 11,801 | $306.0K | 0.00% | +11,801 | New |
| Two Sigma Investments, LP | 11,150 | $289.1K | 0.00% | +11,150 | New |
| Price T Rowe Associates Inc | 10,474 | $272.0K | 0.00% | +10,474 | New |
| Bank of America Corp | 9,574 | $248.3K | 0.00% | +3,792+65.6% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 9,078 | $235.4K | 0.00% | +4,177+85.2% | Added |
| Deutsche Bank AG | 8,885 | $230.4K | 0.00% | 00.0% | Unchanged |
| Virtus Investment Advisers, Inc. | 8,397 | $217.7K | 0.06% | +1,457+21.0% | Added |
| JPMorgan Chase & Co | 7,890 | $204.6K | 0.00% | +3,524+80.7% | Added |
| New York State Common Retirement Fund | 6,700 | $173.7K | 0.00% | +4,400+191.3% | Added |
| Legal & General Group Plc | 5,219 | $135.3K | 0.00% | +977+23.0% | Added |
| Police & Firemen's Retirement System of New Jersey | 5,030 | $130.4K | 0.00% | +2,789+124.5% | Added |
| SG Americas Securities, LLC | 5,015 | $130.0K | 0.00% | +5,015 | New |
| Caption Management, LLC | 4,000 | $103.7K | 0.01% | +4,000 | New |
| CWM, LLC | 2,138 | $55.0K | 0.00% | −128−5.6% | Reduced |
| Tower Research Capital LLC (TRC) | 2,012 | $52.2K | 0.00% | −2,596−56.3% | Reduced |
| China Universal Asset Management Co., Ltd. | 2,000 | $51.9K | 0.00% | +2,000 | New |
| Russell Investments Group, Ltd. | 1,907 | $49.4K | 0.00% | +1,725+947.8% | Added |
| Ameritas Investment Partners, Inc. | 1,632 | $42.3K | 0.00% | +738+82.6% | Added |
| Sterling Capital Management LLC | 1,260 | $32.7K | 0.00% | +1,036+462.5% | Added |
| California State Teachers Retirement System | 555 | $14.4K | 0.00% | +1+0.2% | Added |
| Farther Finance Advisors, LLC | 383 | $9.93K | 0.00% | +383 | New |
| Amalgamated Bank | 305 | $8.00K | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 307 | $7.96K | 0.00% | +307 | New |
| Royal Bank of Canada | 283 | $7.00K | 0.00% | −803−73.9% | Reduced |
| Citigroup Inc | 269 | $6.98K | 0.00% | −12,721−97.9% | Reduced |
| GAMMA Investing LLC | 159 | $4.12K | 0.00% | +108+211.8% | Added |
| EverSource Wealth Advisors, LLC | 149 | $3.86K | 0.00% | +35+30.7% | Added |
| The PNC Financial Services Group, Inc. | 93 | $2.41K | 0.00% | +93 | New |
| SBI Securities Co., Ltd. | 61 | $1.58K | 0.00% | −444−87.9% | Reduced |
| Nisa Investment Advisors, LLC | 26 | $674 | 0.00% | 00.0% | Unchanged |
| Sunbelt Securities, Inc. | 12 | $311 | 0.00% | +12 | New |
| Rothschild Investment LLC | 10 | $259 | 0.00% | +10 | New |
| Essential Partners LLC | 7 | $182 | 0.00% | 00.0% | Unchanged |
| True Wealth Design, LLC | 5 | $130 | 0.00% | 00.0% | Unchanged |
| Ghisallo Capital Management LLC | 0 | $0 | 0.00% | −30,000−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −10,212−100.0% | Sold out |
| IFP Advisors, Inc | 0 | $0 | 0.00% | −3−100.0% | Sold out |
| Congress Wealth Management LLC | – | – | – | – | Not filed |