Skip to main content

Maze Therapeutics, Inc.

MAZE
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001842295

In the last 90 days, Maze Therapeutics, Inc. insiders filed 0 open-market purchases and 14 sales; 161 institutions reported holding it in 13F filings for Q2 2026, worth $1.75B in total; HHLR Advisors (Hillhouse) is the only superinvestor holding it.

Holders of 5% or more of MAZE

Holders whose latest Schedule 13D or 13G filing reports 5% or more of Maze Therapeutics, Inc., largest stake first. The change is against the holder's previous filing.

Holders of 5% or more of MAZE
HolderLatest formStakeChangeFirst filedLatest filingFiling
ARCH Venture Fund X, L.P.13G9.40%4.12M sharesNewMay 15, 20251 filingMay 15, 2025SEC
Third Rock Ventures IV, L.P.13G/A9.30%4.47M shares−4.60 ppfrom 13.90%May 9, 20252 filingsFeb 13, 2026SEC
Deep Track Capital, LP13G/A9.02%3.95M shares+2.11 ppfrom 6.91%Feb 7, 20252 filingsAug 14, 2025SEC
Frazier Life Sciences Public Fund, L.P.13G/A9.00%4.34M shares+1.30 ppfrom 7.70%Feb 10, 20255 filingsFeb 13, 2026SEC
Janus Henderson Group PLC13G/A5.80%2.86M shares−1.50 ppfrom 7.30%May 14, 20254 filingsMay 15, 2026SEC
BlackRock, Inc.13G5.40%2.98M sharesNewJul 29, 20261 filingJul 29, 2026SEC

Stakes are as of each holder's latest filing. Holders whose last filing was in the old format (before December 18, 2024) have no stake on record and are not listed, and after an acquisition or delisting holders usually stop filing.

13D and 13G filings

24 Schedule 13D and 13G filings on Maze Therapeutics, Inc., newest first, including old-format filings without a stake.

Schedule 13D and 13G filings on MAZE
Filed (ET)FilerFormStakeChangeEvent dateFiling
Aug 14, 20264:21 PM ETParadigm Biocapital Advisors LPand 3 others13G/A0.00%0 shares−6.10 ppfrom 6.10%Below 5%Jun 30, 2026SEC
Jul 29, 20263:19 PM ETBlackRock, Inc.13G5.40%2.98M sharesNewJun 30, 2026SEC
May 15, 202612:37 PM ETJanus Henderson Group PLC13G/A5.80%2.86M shares−1.50 ppfrom 7.30%Mar 31, 2026SEC
Apr 1, 20264:00 PM ETParadigm Biocapital Advisors LPand 3 others13G6.10%3.05M sharesNewMar 25, 2026SEC
Feb 13, 20265:31 PM ETFrazier Life Sciences Public Fund, L.P.and 13 others13G/A9.00%4.34M shares+1.30 ppfrom 7.70%Dec 31, 2025SEC
Feb 13, 20265:25 PM ETThird Rock Ventures IV, L.P.and 5 others13G/A9.30%4.47M shares−4.60 ppfrom 13.90%Dec 31, 2025SEC
Feb 6, 20264:32 PM ETGV 2019, L.P.and 8 others13G/A2.90%1.39M shares−2.60 ppfrom 5.50%Below 5%Dec 31, 2025SEC
Nov 14, 20254:04 PM ETForesite Capital Fund IV, L.P.and 4 others13G/A1.40%608.9K shares−4.20 ppfrom 5.60%Below 5%Sep 30, 2025SEC
Nov 14, 202512:49 PM ETJanus Henderson Group PLC13G/A7.30%3.21M shares+1.30 ppfrom 6.00%Sep 30, 2025SEC
Nov 13, 20254:10 PM ETMatrix Capital Management Company, LPand 1 other13G/A3.50%1.65M shares−2.20 ppfrom 5.70%Below 5%Sep 30, 2025SEC
Aug 14, 20251:43 PM ETFrazier Life Sciences Public Fund, L.P.and 16 others13G/A7.70%3.35M shares−2.50 ppfrom 10.20%Jun 30, 2025SEC
Aug 14, 202511:46 AM ETJanus Henderson Group PLC13G/A6.00%2.63M shares+0.30 ppfrom 5.70%Mar 31, 2025SEC
Aug 14, 20258:48 AM ETDeep Track Capital, LPand 2 others13G/A9.02%3.95M shares+2.11 ppfrom 6.91%Jun 30, 2025SEC
May 15, 20255:05 PM ETARCH Venture Fund X, L.P.and 8 others13G9.40%4.12M sharesNewMar 31, 2025SEC
May 14, 20254:10 PM ETMatrix Capital Management Company, LPand 1 other13G5.70%2.49M sharesNewMar 31, 2025SEC
May 14, 202511:48 AM ETJanus Henderson Group PLC13G5.70%2.50M sharesNewMar 31, 2025SEC
May 9, 20254:15 PM ETGV 2019, L.P.and 8 others13G5.50%2.41M sharesNewMar 31, 2025SEC
May 9, 20254:15 PM ETThird Rock Ventures IV, L.P.and 5 others13G13.90%6.07M sharesNewJan 31, 2025SEC
Apr 29, 20259:59 AM ETFrazier Life Sciences Public Fund, L.P.and 16 others13G/A10.20%4.45M shares+0.80 ppfrom 9.40%Apr 25, 2025SEC
Apr 29, 20259:58 AM ETFrazier Life Sciences Public Fund, L.P.and 16 others13G/A9.40%4.13M shares+2.10 ppfrom 7.30%Mar 31, 2025SEC
Feb 10, 202510:55 AM ETFrazier Life Sciences Public Fund, L.P.and 16 others13G7.30%3.19M sharesNewFeb 3, 2025SEC
Feb 7, 20254:30 PM ETDeep Track Capital, LPand 2 others13G6.91%3.02M sharesNewJan 31, 2025SEC
Feb 7, 20254:01 PM ETForesite Capital Fund IV, L.P.and 4 others13G5.60%2.46M shares0.00 ppfrom 5.60%Jan 31, 2025SEC
Feb 7, 20254:01 PM ETForesite Capital Fund IV, L.P.and 4 others13G5.60%2.46M sharesNewJan 31, 2025SEC

Form 144: proposed insider sales

Notices from officers, directors and other affiliates planning to sell Maze Therapeutics, Inc. shares.

No Form 144 notices for Maze Therapeutics, Inc. are on file.