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Maze Therapeutics, Inc.

MAZE
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001842295

In the last 90 days, Maze Therapeutics, Inc. insiders filed 0 open-market purchases and 13 sales; 161 institutions reported holding it in 13F filings for Q2 2026, worth $1.75B in total; HHLR Advisors (Hillhouse) is the only superinvestor holding it.

13F holders, Q3 2025

Institutional positions in Maze Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
94
+20 vs. Q2 2025
Shares held
43.0M
+4.16M (+10.7%) vs. Q2 2025
Total value
$1.11B
+$637.9M (+133.9%) vs. Q2 2025
New holders
23
39 more added
Sold out
3
15 more reduced

1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MAZE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 94 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 68 institutionsQ2 2025: 75 institutionsQ3 2025: 94 institutionsQ4 2025: 143 institutionsQ1 2026: 165 institutionsQ2 2026: 161 institutions
Value heldQ3 2025: $1.11B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $441.4MQ2 2025: $476.7MQ3 2025: $1.11BQ4 2025: $2.00BQ1 2026: $1.54BQ2 2026: $1.75B
Institutions holding MAZE and their total value by quarter
QuarterHoldersValue
Q2 2026161$1.75B
Q1 2026165$1.54B
Q4 2025143$2.00B
Q3 202594$1.11B
Q2 202575$476.7M
Q1 202568$441.4M
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Maze Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding MAZE in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
True Wealth Design, LLC5$1300.00%00.0%Unchanged
Essential Partners LLC7$1820.00%00.0%Unchanged
Rothschild Investment LLC10$2590.00%+10New
Sunbelt Securities, Inc.12$3110.00%+12New
Nisa Investment Advisors, LLC26$6740.00%00.0%Unchanged
SBI Securities Co., Ltd.61$1.58K0.00%−444−87.9%Reduced
The PNC Financial Services Group, Inc.93$2.41K0.00%+93New
EverSource Wealth Advisors, LLC149$3.86K0.00%+35+30.7%Added
GAMMA Investing LLC159$4.12K0.00%+108+211.8%Added
Citigroup Inc269$6.98K0.00%−12,721−97.9%Reduced
Royal Bank of Canada283$7.00K0.00%−803−73.9%Reduced
SRS Capital Advisors, Inc.307$7.96K0.00%+307New
Amalgamated Bank305$8.00K0.00%00.0%Unchanged
Farther Finance Advisors, LLC383$9.93K0.00%+383New
California State Teachers Retirement System555$14.4K0.00%+1+0.2%Added
Sterling Capital Management LLC1,260$32.7K0.00%+1,036+462.5%Added
Ameritas Investment Partners, Inc.1,632$42.3K0.00%+738+82.6%Added
Russell Investments Group, Ltd.1,907$49.4K0.00%+1,725+947.8%Added
China Universal Asset Management Co., Ltd.2,000$51.9K0.00%+2,000New
Tower Research Capital LLC (TRC)2,012$52.2K0.00%−2,596−56.3%Reduced
CWM, LLC2,138$55.0K0.00%−128−5.6%Reduced
Caption Management, LLC4,000$103.7K0.01%+4,000New
SG Americas Securities, LLC5,015$130.0K0.00%+5,015New
Police & Firemen's Retirement System of New Jersey5,030$130.4K0.00%+2,789+124.5%Added
Legal & General Group Plc5,219$135.3K0.00%+977+23.0%Added
New York State Common Retirement Fund6,700$173.7K0.00%+4,400+191.3%Added
JPMorgan Chase & Co7,890$204.6K0.00%+3,524+80.7%Added
Virtus Investment Advisers, Inc.8,397$217.7K0.06%+1,457+21.0%Added
Deutsche Bank AG8,885$230.4K0.00%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.9,078$235.4K0.00%+4,177+85.2%Added
Bank of America Corp9,574$248.3K0.00%+3,792+65.6%Added
Price T Rowe Associates Inc10,474$272.0K0.00%+10,474New
Two Sigma Investments, LP11,150$289.1K0.00%+11,150New
MetLife Investment Management11,801$306.0K0.00%+11,801New
BNP Paribas Arbitrage, SA12,018$311.6K0.00%+11,259+1,483.4%Added
Alps Advisors Inc13,742$356.3K0.00%−9,835−41.7%Reduced
Winton Group Ltd14,487$375.6K0.01%+14,487New
Wells Fargo & Company14,779$383.2K0.00%+9,164+163.2%Added
Susquehanna International Group, LLP16,165$419.2K0.00%+5,598+53.0%Added
STRS Ohio17,900$464.1K0.00%−29,000−61.8%Reduced
Franklin Resources Inc18,198$471.9K0.00%+18,198New
Rhumbline Advisers20,970$543.7K0.00%+13,256+171.8%Added
ADAR1 Capital Management, LLC26,045$675.3K0.07%+26,045New
XTX Topco Ltd26,867$696.7K0.04%+26,867New
Barclays PLC27,516$713.5K0.00%+12,875+87.9%Added
AQR Capital Management LLC27,615$716.1K0.00%+148+0.5%Added
UBS Group AG27,793$720.7K0.00%−23,609−45.9%Reduced
Nuveen, LLC30,304$785.8K0.00%+18,929+166.4%Added
Advisor Group Holdings, Inc.30,525$791.5K0.00%+30,471+56,427.8%Added
Bank of New York Mellon Corp45,240$1.17M0.00%+23,694+110.0%Added
Alliancebernstein L.P.60,100$1.56M0.00%+28,304+89.0%Added
Ensign Peak Advisors, Inc70,665$1.83M0.00%+52,126+281.2%Added
Renaissance Technologies LLC86,100$2.23M0.00%+86,100New
Foresite Capital Management V, LLC86,291$2.24M2.06%−258,900−75.0%Reduced
Harvard Management Co Inc92,396$2.40M0.11%−545,132−85.5%Reduced
Nantahala Capital Management, LLC93,351$2.42M0.15%+93,351New
Schonfeld Strategic Advisors LLC114,049$2.96M0.02%+114,049New
Alyeska Investment Group, L.P.125,000$3.24M0.01%00.0%Unchanged
Invesco Ltd.132,062$3.42M0.00%+113,632+616.6%Added
Sphera Funds Management Ltd.154,343$4.00M0.95%−202,110−56.7%Reduced
Charles Schwab Investment Management Inc167,928$4.35M0.00%+92,757+123.4%Added
Northern Trust Corp176,890$4.59M0.00%+91,344+106.8%Added
Octagon Capital Advisors LP177,667$4.61M0.72%00.0%Unchanged
Parkman Healthcare Partners LLC200,000$5.19M0.57%+200,000New
Washington University210,681$5.46M3.06%+210,681New
Morgan Stanley212,762$5.52M0.00%+180,981+569.5%Added
Boothbay Fund Management, LLC351,875$9.12M0.24%+276,345+365.9%Added
Driehaus Capital Management LLC378,015$9.80M0.07%+184,615+95.5%Added
State Street Corp384,702$9.98M0.00%+240,017+165.9%Added
Balyasny Asset Management LLC433,725$11.2M0.02%+433,725New
HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse)457,535$11.9M0.29%00.0%Unchanged
Geode Capital Management, LLC473,549$12.3M0.00%+242,312+104.8%Added
Bessemer Group Inc481,790$12.5M0.02%00.0%Unchanged
Foresite Capital Management IV, LLC522,657$13.6M7.42%−1,589,262−75.3%Reduced
ArrowMark Colorado Holdings LLC545,132$14.1M0.26%+545,132New
FMR LLC655,614$17.0M0.00%+101,080+18.2%Added
Ikarian Capital, LLC740,825$19.2M4.35%+478,085+182.0%Added
Janus Henderson Group PLC751,874$19.5M0.01%−649,386−46.3%Reduced
Casdin Capital, LLC758,857$19.7M1.64%00.0%Unchanged
Marshall Wace, LLP777,701$20.2M0.02%+758,104+3,868.5%Added
TRV GP V, LLC950,800$24.7M6.97%00.0%Unchanged
Woodline Partners LP1,035,229$26.8M0.13%+94,529+10.0%Added
General Catalyst Group Management, LLC1,035,910$26.9M0.88%00.0%Unchanged
Logos Global Management LP1,227,300$31.8M3.14%+615,386+100.6%Added
VR Adviser, LLC1,230,769$31.9M1.80%+1,230,769New
BlackRock, Inc.1,316,016$34.1M0.00%+701,312+114.1%Added
Vanguard Group Inc1,334,955$34.6M0.00%+915,342+218.1%Added
Matrix Capital Management Company, LP1,653,684$42.9M40.17%−832,500−33.5%Reduced
AH Capital Management, L.L.C.1,702,225$44.1M3.16%00.0%Unchanged
Alphabet Inc.2,412,471$62.6M2.60%00.0%Unchanged
Deep Track Capital, LP3,948,910$102.4M2.86%00.0%Unchanged
ARCH Venture Management, LLC4,120,053$106.8M21.70%00.0%Unchanged
Frazier Life Sciences Management, L.P.4,567,274$118.4M3.55%−10.0%Reduced
TRV GP IV, LLC6,073,958$157.5M57.49%00.0%Unchanged
Ghisallo Capital Management LLC0$00.00%−30,000−100.0%Sold out
Engineers Gate Manager LP0$00.00%−10,212−100.0%Sold out
IFP Advisors, Inc0$00.00%−3−100.0%Sold out
Congress Wealth Management LLC––––Not filed