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Maze Therapeutics, Inc.

MAZE
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001842295

In the last 90 days, Maze Therapeutics, Inc. insiders filed 0 open-market purchases and 14 sales; 161 institutions reported holding it in 13F filings for Q2 2026, worth $1.75B in total; HHLR Advisors (Hillhouse) is the only superinvestor holding it.

13F holders, Q2 2026

Institutional positions in Maze Therapeutics, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
161
−1 vs. Q1 2026
Shares held
58.5M
+9.72M (+19.9%) vs. Q1 2026
Total value
$1.75B
+$287.9M (+19.8%) vs. Q1 2026
New holders
38
66 more added
Sold out
39
38 more reduced

3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MAZE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 161 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 68 institutionsQ2 2025: 75 institutionsQ3 2025: 94 institutionsQ4 2025: 143 institutionsQ1 2026: 165 institutionsQ2 2026: 161 institutions
Value heldQ2 2026: $1.75B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $441.4MQ2 2025: $476.7MQ3 2025: $1.11BQ4 2025: $2.00BQ1 2026: $1.54BQ2 2026: $1.75B
Institutions holding MAZE and their total value by quarter
QuarterHoldersValue
Q2 2026161$1.75B
Q1 2026165$1.54B
Q4 2025143$2.00B
Q3 202594$1.11B
Q2 202575$476.7M
Q1 202568$441.4M
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Maze Therapeutics, Inc.; share changes are against Q1 2026.

Institutions holding MAZE in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Frazier Life Sciences Management, L.P.5,032,915$150.2M3.27%+465,641+10.2%Added
TRV GP IV, LLC4,473,958$133.5M52.63%00.0%Unchanged
ARCH Venture Management, LLC4,120,053$123.0M11.18%00.0%Unchanged
Deep Track Capital, LP3,732,569$111.4M1.64%+255,007+7.3%Added
BlackRock, Inc.3,502,841$104.5M0.00%+932,416+36.3%Added
Jupiter Topco LLC3,408,045$101.8M0.04%+3,408,045New
T. Rowe Price Investment Management, Inc.2,603,682$77.7M0.05%+2,603,682New
Logos Global Management LP1,935,000$57.7M2.49%+700,000+56.7%Added
Vanguard Capital Management LLC1,778,222$53.1M0.00%+342,566+23.9%Added
AH Capital Management, L.L.C.1,702,225$50.8M0.36%00.0%Unchanged
VR Adviser, LLC1,602,034$47.8M1.45%00.0%Unchanged
Alphabet Inc.1,388,583$41.4M0.04%00.0%Unchanged
Braidwell LP1,140,040$34.0M1.26%+1,140,040New
Farallon Capital Management, L.L.C.1,107,814$33.1M0.19%+734,814+197.0%Added
FMR LLC1,056,959$31.5M0.00%+192,745+22.3%Added
General Catalyst Group Management, LLC1,035,910$30.9M16.40%00.0%Unchanged
State Street Corp997,533$29.8M0.00%+360,811+56.7%Added
Driehaus Capital Management LLC954,886$28.5M0.17%+318,724+50.1%Added
TRV GP V, LLC950,800$28.4M5.69%00.0%Unchanged
JPMorgan Chase & Co964,011$28.0M0.00%+905,565+1,549.4%Added
Marshall Wace, LLP914,572$27.3M0.02%+603,933+194.4%Added
Geode Capital Management, LLC858,054$25.6M0.00%+258,087+43.0%Added
Citadel Advisors LLC852,676$25.4M0.01%+76,962+9.9%Added
Casdin Capital, LLC843,857$25.2M1.26%+85,000+11.2%Added
ArrowMark Colorado Holdings LLC767,383$22.9M0.95%00.0%Unchanged
Woodline Partners LP736,216$22.0M0.07%+85,987+13.2%Added
Bessemer Group Inc481,790$14.4M0.02%00.0%Unchanged
Sphera Funds Management Ltd.417,564$12.5M1.78%+190,221+83.7%Added
Vanguard Portfolio Management LLC393,107$11.7M0.00%+197,565+101.0%Added
Standard Life Aberdeen plc383,773$11.5M0.02%+157,546+69.6%Added
Ikarian Capital, LLC378,999$11.3M1.85%00.0%Unchanged
HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse)366,028$10.9M1.31%00.0%Unchanged
ADAR1 Capital Management, LLC339,276$10.1M0.48%+289,181+577.3%Added
Squadron Capital Management LLC335,000$10.0M3.42%+77,500+30.1%Added
Bank of America Corp321,227$9.59M0.00%+126,143+64.7%Added
Northern Trust Corp294,742$8.80M0.00%+83,360+39.4%Added
Goldman Sachs Group Inc293,144$8.75M0.00%+13,431+4.8%Added
Candriam Luxembourg S.C.A.273,932$8.17M0.04%−4,235−1.5%Reduced
Hudson Bay Capital Management LP270,000$8.06M0.04%+261,850+3,212.9%Added
Charles Schwab Investment Management Inc260,566$7.78M0.00%+74,133+39.8%Added
Adage Capital Partners GP, L.L.C.248,000$7.40M0.01%−930,000−78.9%Reduced
Mass General Brigham, Inc239,994$7.16M1.98%00.0%Unchanged
Ameriprise Financial Inc227,425$6.79M0.00%+119,939+111.6%Added
Vanguard Fiduciary Trust Co219,938$6.56M0.00%+68,938+45.7%Added
RTW Investments, LP212,000$6.33M0.05%+212,000New
Schroder Investment Management Group199,872$5.80M0.00%+162,691+437.6%Added
Two Sigma Investments, LP192,952$5.76M0.00%+177,107+1,117.7%Added
Boothbay Fund Management, LLC188,857$5.64M0.11%−95,619−33.6%Reduced
ExodusPoint Capital Management, LP183,264$5.47M0.05%+183,264New
SummitTX Capital, L.P.176,291$5.26M0.14%+92,541+110.5%Added
HighVista Strategies LLC136,572$4.08M0.93%+36,722+36.8%Added
Morgan Stanley135,168$4.03M0.00%−69,663−34.0%Reduced
Price T Rowe Associates Inc132,870$3.96M0.00%+10,175+8.3%Added
Qube Research & Technologies Ltd131,043$3.91M0.00%−3,907−2.9%Reduced
Walleye Capital LLC128,006$3.82M0.02%+100,061+358.1%Added
Exome Asset Management LLC114,692$3.42M2.11%+26,182+29.6%Added
Ensign Peak Advisors, Inc101,644$3.03M0.00%−84,150−45.3%Reduced
Alyeska Investment Group, L.P.100,000$2.98M0.01%00.0%Unchanged
Bank of New York Mellon Corp97,588$2.91M0.00%+23,320+31.4%Added
Algert Global LLC93,357$2.79M0.03%+93,357New
UBS Group AG84,679$2.53M0.00%−9,219−9.8%Reduced
Wellington Management Group LLP82,724$2.47M0.00%+22,137+36.5%Added
Trexquant Investment LP81,668$2.44M0.02%+81,668New
Franklin Resources Inc80,216$2.39M0.00%+20,579+34.5%Added
Nuveen, LLC78,468$2.34M0.00%+15,108+23.8%Added
Advisor Group Holdings, Inc.77,850$2.32M0.00%+17,907+29.9%Added
BNP Paribas Arbitrage, SA77,251$2.31M0.00%+70,776+1,093.1%Added
XTX Topco Ltd75,317$2.25M0.03%+48,463+180.5%Added
Los Angeles Capital Management LLC74,384$2.22M0.01%+64,964+689.6%Added
Raymond James Financial Inc66,353$1.98M0.00%−3,022−4.4%Reduced
Jacobs Levy Equity Management, Inc65,468$1.95M0.01%+65,468New
DAFNA Capital Management LLC65,000$1.94M0.37%+30,000+85.7%Added
Alps Advisors Inc55,970$1.67M0.01%+16,799+42.9%Added
Jump Financial, LLC47,129$1.41M0.01%+47,129New
Swiss National Bank47,100$1.41M0.00%+47,100New
First Trust Advisors LP46,227$1.38M0.00%+20,742+81.4%Added
Propel Bio Management, LLC43,798$1.31M0.68%00.0%Unchanged
Rhumbline Advisers42,873$1.28M0.00%+11,360+36.0%Added
Alliancebernstein L.P.37,800$1.13M0.00%−26,962−41.6%Reduced
Deutsche Bank AG34,993$1.04M0.00%+14,730+72.7%Added
Wells Fargo & Company32,047$956.3K0.00%+21,678+209.1%Added
Citigroup Inc30,265$903.1K0.00%+21,702+253.4%Added
Quadrature Capital Ltd30,047$896.6K0.01%+30,047New
Invesco Ltd.28,372$846.6K0.00%−58,047−67.2%Reduced
AQR Capital Management LLC27,161$810.5K0.00%−784−2.8%Reduced
California State Teachers Retirement System26,063$777.7K0.00%+24,628+1,716.2%Added
State of Wisconsin Investment Board23,840$711.4K0.00%+23,840New
Barclays PLC23,733$708.2K0.00%+14,471+156.2%Added
Susquehanna International Group, LLP23,677$706.5K0.00%−1,624−6.4%Reduced
TD Asset Management Inc22,174$661.7K0.00%+22,174New
MetLife Investment Management20,899$623.6K0.00%+6,357+43.7%Added
Balyasny Asset Management LLC20,190$602.5K0.00%−440,961−95.6%Reduced
Squarepoint Ops LLC19,434$579.9K0.00%+5,822+42.8%Added
Verition Fund Management LLC18,201$543.1K0.00%−933−4.9%Reduced
UBS Asset Management Americas Inc17,739$529.3K0.00%+17,312+4,054.3%Added
Jackson Creek Investment Advisors LLC18,345$494.0K0.16%+18,345New
Vanguard Asset Management, Ltd16,436$490.4K0.00%+16,436New
Manufacturers Life Insurance Company, The16,402$489.4K0.00%+1,832+12.6%Added
Mirae Asset Global ETFs Holdings Ltd.16,248$484.8K0.00%+3,832+30.9%Added
Legal & General Group Plc15,781$470.9K0.00%+9,991+172.6%Added