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Maze Therapeutics, Inc.

MAZE
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001842295

In the last 90 days, Maze Therapeutics, Inc. insiders filed 0 open-market purchases and 14 sales; 161 institutions reported holding it in 13F filings for Q2 2026, worth $1.75B in total; HHLR Advisors (Hillhouse) is the only superinvestor holding it.

13F holders, Q2 2025

Institutional positions in Maze Therapeutics, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
75
+7 vs. Q1 2025
Shares held
38.8M
−1.20M (−3.0%) vs. Q1 2025
Total value
$476.7M
+$35.3M (+8.0%) vs. Q1 2025
New holders
14
25 more added
Sold out
7
14 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MAZE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 75 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 68 institutionsQ2 2025: 75 institutionsQ3 2025: 94 institutionsQ4 2025: 143 institutionsQ1 2026: 165 institutionsQ2 2026: 161 institutions
Value heldQ2 2025: $476.7M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $441.4MQ2 2025: $476.7MQ3 2025: $1.11BQ4 2025: $2.00BQ1 2026: $1.54BQ2 2026: $1.75B
Institutions holding MAZE and their total value by quarter
QuarterHoldersValue
Q2 2026161$1.75B
Q1 2026165$1.54B
Q4 2025143$2.00B
Q3 202594$1.11B
Q2 202575$476.7M
Q1 202568$441.4M
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Maze Therapeutics, Inc.; share changes are against Q1 2025.

Institutions holding MAZE in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
TRV GP IV, LLC6,073,958$74.5M45.63%00.0%Unchanged
Frazier Life Sciences Management, L.P.4,567,275$56.0M2.24%+438,274+10.6%Added
ARCH Venture Management, LLC4,120,053$50.6M16.91%00.0%Unchanged
Deep Track Capital, LP3,948,910$48.5M1.56%+679,784+20.8%Added
Matrix Capital Management Company, LP2,486,184$30.5M13.69%00.0%Unchanged
Alphabet Inc.2,412,471$29.6M1.39%00.0%Unchanged
Foresite Capital Management IV, LLC2,111,919$25.9M20.93%00.0%Unchanged
AH Capital Management, L.L.C.1,702,225$20.9M6.67%00.0%Unchanged
Janus Henderson Group PLC1,401,260$17.3M0.01%+154,890+12.4%Added
General Catalyst Group Management, LLC1,035,910$12.7M0.30%00.0%Unchanged
TRV GP V, LLC950,800$11.7M7.04%00.0%Unchanged
Woodline Partners LP940,700$11.5M0.06%+11,598+1.2%Added
Casdin Capital, LLC758,857$9.31M0.85%−187,500−19.8%Reduced
Harvard Management Co Inc637,528$7.82M0.54%00.0%Unchanged
BlackRock, Inc.614,704$7.54M0.00%+32,116+5.5%Added
Logos Global Management LP611,914$7.51M1.00%−325,000−34.7%Reduced
FMR LLC554,534$6.80M0.00%−413,849−42.7%Reduced
Bessemer Group Inc481,790$5.91M0.01%00.0%Unchanged
HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse)457,535$5.61M0.18%00.0%Unchanged
Vanguard Group Inc419,613$5.15M0.00%−246,941−37.0%Reduced
Sphera Funds Management Ltd.356,453$4.37M1.14%+899+0.3%Added
Foresite Capital Management V, LLC345,191$4.24M5.25%00.0%Unchanged
Ikarian Capital, LLC262,740$3.22M1.07%−60,000−18.6%Reduced
Geode Capital Management, LLC231,237$2.84M0.00%+18,773+8.8%Added
Driehaus Capital Management LLC193,400$2.37M0.02%+61,285+46.4%Added
Octagon Capital Advisors LP177,667$2.18M0.48%−290,333−62.0%Reduced
State Street Corp144,685$1.78M0.00%+79,972+123.6%Added
Alyeska Investment Group, L.P.125,000$1.53M0.01%00.0%Unchanged
Northern Trust Corp85,546$1.05M0.00%+14,708+20.8%Added
Boothbay Fund Management, LLC75,530$926.8K0.03%−21,438−22.1%Reduced
Charles Schwab Investment Management Inc75,171$922.3K0.00%+2,866+4.0%Added
UBS Group AG51,402$630.7K0.00%−36,662−41.6%Reduced
STRS Ohio46,900$575.5K0.00%+45,300+2,831.3%Added
Alliancebernstein L.P.31,796$390.1K0.00%−984,650−96.9%Reduced
Morgan Stanley31,781$390.0K0.00%+7,888+33.0%Added
Congress Wealth Management LLC30,235$371.0K0.00%+30,235New
Ghisallo Capital Management LLC30,000$368.1K0.01%00.0%Unchanged
AQR Capital Management LLC27,467$337.0K0.00%+27,467New
Alps Advisors Inc23,577$289.3K0.00%+23,577New
Bank of New York Mellon Corp21,546$264.4K0.00%+4,313+25.0%Added
Marshall Wace, LLP19,597$240.5K0.00%00.0%Unchanged
Ensign Peak Advisors, Inc18,539$227.5K0.00%+18,539New
Invesco Ltd.18,430$226.1K0.00%−2,122−10.3%Reduced
Barclays PLC14,641$179.6K0.00%−30.0%Reduced
Citigroup Inc12,990$159.4K0.00%+6,774+109.0%Added
Nuveen, LLC11,375$139.6K0.00%00.0%Unchanged
Susquehanna International Group, LLP10,567$129.7K0.00%−41−0.4%Reduced
Engineers Gate Manager LP10,212$125.3K0.00%+10,212New
Deutsche Bank AG8,885$109.0K0.00%00.0%Unchanged
Rhumbline Advisers7,714$94.6K0.00%+479+6.6%Added
Virtus Investment Advisers, Inc.6,940$85.2K0.03%+6,940New
Bank of America Corp5,782$70.9K0.00%+1,455+33.6%Added
Wells Fargo & Company5,615$68.9K0.00%+922+19.6%Added
Mirae Asset Global ETFs Holdings Ltd.4,901$60.1K0.00%−234−4.6%Reduced
Tower Research Capital LLC (TRC)4,608$56.5K0.00%+3,774+452.5%Added
JPMorgan Chase & Co4,366$53.6K0.00%−5,775−56.9%Reduced
Legal & General Group Plc4,242$52.0K0.00%+3,371+387.0%Added
New York State Common Retirement Fund2,300$28.2K0.00%00.0%Unchanged
CWM, LLC2,266$28.0K0.00%+2,266New
Police & Firemen's Retirement System of New Jersey2,241$27.5K0.00%00.0%Unchanged
Royal Bank of Canada1,086$13.0K0.00%+953+716.5%Added
Ameritas Investment Partners, Inc.894$11.0K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA759$9.31K0.00%+359+89.8%Added
California State Teachers Retirement System554$6.80K0.00%00.0%Unchanged
SBI Securities Co., Ltd.505$6.20K0.00%+479+1,842.3%Added
Amalgamated Bank305$4.00K0.00%00.0%Unchanged
Sterling Capital Management LLC224$2.75K0.00%+150+202.7%Added
Russell Investments Group, Ltd.182$2.23K0.00%+182New
EverSource Wealth Advisors, LLC114$1.40K0.00%+114New
GAMMA Investing LLC51$6260.00%+51New
Advisor Group Holdings, Inc.54$5950.00%+54New
Nisa Investment Advisors, LLC26$3190.00%+8+44.4%Added
Essential Partners LLC7$860.00%+7New
True Wealth Design, LLC5$620.00%+5New
IFP Advisors, Inc3$370.00%+3New
Affinity Asset Advisors, LLC0$00.00%−250,000−100.0%Sold out
Citadel Advisors LLC0$00.00%−20,000−100.0%Sold out
Oxford Asset Management LLP0$00.00%−17,000−100.0%Sold out
Davidson Kempner Capital Management LP0$00.00%−13,670−100.0%Sold out
Goldman Sachs Group Inc0$00.00%−13,129−100.0%Sold out
Corebridge Financial, Inc.0$00.00%−4,328−100.0%Sold out
Comerica Bank0$00.00%−636−100.0%Sold out