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Maze Therapeutics, Inc.

MAZE
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001842295

In the last 90 days, Maze Therapeutics, Inc. insiders filed 0 open-market purchases and 14 sales; 161 institutions reported holding it in 13F filings for Q2 2026, worth $1.75B in total; HHLR Advisors (Hillhouse) is the only superinvestor holding it.

13F holders, Q1 2025

Institutional positions in Maze Therapeutics, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
68
+68 vs. Q4 2024
Shares held
40.0M
+40.0M vs. Q4 2024
Total value
$441.4M
+$441.4M vs. Q4 2024
New holders
68
0 more added
Sold out
0
0 more reduced

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MAZE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 68 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 68 institutionsQ2 2025: 75 institutionsQ3 2025: 94 institutionsQ4 2025: 143 institutionsQ1 2026: 165 institutionsQ2 2026: 161 institutions
Value heldQ1 2025: $441.4M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $441.4MQ2 2025: $476.7MQ3 2025: $1.11BQ4 2025: $2.00BQ1 2026: $1.54BQ2 2026: $1.75B
Institutions holding MAZE and their total value by quarter
QuarterHoldersValue
Q2 2026161$1.75B
Q1 2026165$1.54B
Q4 2025143$2.00B
Q3 202594$1.11B
Q2 202575$476.7M
Q1 202568$441.4M
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Maze Therapeutics, Inc.; share changes are against Q4 2024.

Institutions holding MAZE in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
TRV GP IV, LLC6,073,958$66.9M72.02%+6,073,958New
Frazier Life Sciences Management, L.P.4,129,001$45.5M2.08%+4,129,001New
ARCH Venture Management, LLC4,120,053$45.4M22.00%+4,120,053New
Deep Track Capital, LP3,269,126$36.0M1.17%+3,269,126New
Matrix Capital Management Company, LP2,486,184$27.4M7.88%+2,486,184New
Alphabet Inc.2,412,471$26.6M1.68%+2,412,471New
Foresite Capital Management IV, LLC2,111,919$23.3M20.93%+2,111,919New
AH Capital Management, L.L.C.1,702,225$18.7M2.67%+1,702,225New
Janus Henderson Group PLC1,246,370$14.3M0.01%+1,246,370New
General Catalyst Group Management, LLC1,035,910$11.4M1.29%+1,035,910New
Alliancebernstein L.P.1,016,446$11.2M0.00%+1,016,446New
FMR LLC968,383$10.7M0.00%+968,383New
TRV GP V, LLC950,800$10.5M8.37%+950,800New
Casdin Capital, LLC946,357$10.4M0.85%+946,357New
Logos Global Management LP936,914$10.3M1.83%+936,914New
Woodline Partners LP929,102$10.2M0.07%+929,102New
Vanguard Group Inc666,554$7.34M0.00%+666,554New
Harvard Management Co Inc637,528$7.02M0.62%+637,528New
BlackRock, Inc.582,588$6.41M0.00%+582,588New
Bessemer Group Inc481,790$5.30M0.01%+481,790New
Octagon Capital Advisors LP468,000$5.15M1.12%+468,000New
HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse)457,535$5.04M0.14%+457,535New
Sphera Funds Management Ltd.355,554$3.91M0.97%+355,554New
Foresite Capital Management V, LLC345,191$3.80M4.34%+345,191New
Ikarian Capital, LLC322,740$3.55M1.16%+322,740New
Affinity Asset Advisors, LLC250,000$2.75M0.43%+250,000New
Geode Capital Management, LLC212,464$2.34M0.00%+212,464New
Driehaus Capital Management LLC132,115$1.45M0.01%+132,115New
Alyeska Investment Group, L.P.125,000$1.38M0.01%+125,000New
Boothbay Fund Management, LLC96,968$1.07M0.04%+96,968New
UBS Group AG88,064$969.6K0.00%+88,064New
Charles Schwab Investment Management Inc72,305$796.1K0.00%+72,305New
Northern Trust Corp70,838$779.9K0.00%+70,838New
State Street Corp64,713$712.5K0.00%+64,713New
Ghisallo Capital Management LLC30,000$330.3K0.03%+30,000New
Morgan Stanley23,893$263.1K0.00%+23,893New
Invesco Ltd.20,552$226.3K0.00%+20,552New
Citadel Advisors LLC20,000$220.2K0.00%+20,000New
Marshall Wace, LLP19,597$215.8K0.00%+19,597New
Bank of New York Mellon Corp17,233$189.7K0.00%+17,233New
Oxford Asset Management LLP17,000$187.2K0.09%+17,000New
Barclays PLC14,644$161.2K0.00%+14,644New
Davidson Kempner Capital Management LP13,670$150.5K0.00%+13,670New
Goldman Sachs Group Inc13,129$144.6K0.00%+13,129New
Nuveen, LLC11,375$125.2K0.00%+11,375New
Susquehanna International Group, LLP10,608$116.8K0.00%+10,608New
JPMorgan Chase & Co10,141$111.7K0.00%+10,141New
Deutsche Bank AG8,885$97.8K0.00%+8,885New
Rhumbline Advisers7,235$79.7K0.00%+7,235New
Citigroup Inc6,216$68.4K0.00%+6,216New
Mirae Asset Global ETFs Holdings Ltd.5,135$56.5K0.00%+5,135New
Wells Fargo & Company4,693$51.7K0.00%+4,693New
Corebridge Financial, Inc.4,328$47.7K0.00%+4,328New
Bank of America Corp4,327$47.6K0.00%+4,327New
New York State Common Retirement Fund2,300$25.3K0.00%+2,300New
Police & Firemen's Retirement System of New Jersey2,241$24.7K0.00%+2,241New
STRS Ohio1,600$17.6K0.00%+1,600New
Ameritas Investment Partners, Inc.894$9.84K0.00%+894New
Legal & General Group Plc871$9.59K0.00%+871New
Tower Research Capital LLC (TRC)834$9.18K0.00%+834New
Comerica Bank636$7.00K0.00%+636New
California State Teachers Retirement System554$6.10K0.00%+554New
BNP Paribas Arbitrage, SA400$4.40K0.00%+400New
Amalgamated Bank305$3.00K0.00%+305New
Royal Bank of Canada133$1.00K0.00%+133New
Sterling Capital Management LLC74$8150.00%+74New
SBI Securities Co., Ltd.26$2860.00%+26New
Nisa Investment Advisors, LLC18$1980.00%+18New