Maze Therapeutics, Inc.
MAZE- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001842295
In the last 90 days, Maze Therapeutics, Inc. insiders filed 0 open-market purchases and 14 sales; 161 institutions reported holding it in 13F filings for Q2 2026, worth $1.75B in total; HHLR Advisors (Hillhouse) is the only superinvestor holding it.
13F holders, Q1 2026
Institutional positions in Maze Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 165
- +24 vs. Q4 2025
- Shares held
- 51.7M
- +5.01M (+10.7%) vs. Q4 2025
- Total value
- $1.54B
- −$390.0M (−20.2%) vs. Q4 2025
- New holders
- 49
- 58 more added
- Sold out
- 25
- 36 more reduced
2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting MAZE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 161 | $1.75B |
| Q1 2026 | 165 | $1.54B |
| Q4 2025 | 143 | $2.00B |
| Q3 2025 | 94 | $1.11B |
| Q2 2025 | 75 | $476.7M |
| Q1 2025 | 68 | $441.4M |
| Q4 2024 | 0 | $0 |
| Q3 2024 | 0 | $0 |
| Q2 2024 | 0 | $0 |
| Q1 2024 | 0 | $0 |
| Q4 2023 | 0 | $0 |
| Q3 2023 | 0 | $0 |
| Q2 2023 | 0 | $0 |
| Q1 2023 | 0 | $0 |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Maze Therapeutics, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | 4,567,274 | $136.3M | 3.51% | 00.0% | Unchanged |
| TRV GP IV, LLC | 4,473,958 | $133.5M | 50.04% | 00.0% | Unchanged |
| ARCH Venture Management, LLC | 4,120,053 | $123.0M | 18.16% | 00.0% | Unchanged |
| Deep Track Capital, LP | 3,477,562 | $103.8M | 2.14% | −768,878−18.1% | Reduced |
| Janus Henderson Group PLC | 2,858,876 | $85.3M | 0.04% | −283,711−9.0% | Reduced |
| Paradigm Biocapital Advisors LP | 2,744,399 | $81.9M | 1.67% | +2,744,399 | New |
| BlackRock, Inc. | 2,570,425 | $76.7M | 0.00% | +283,270+12.4% | Added |
| AH Capital Management, L.L.C. | 1,702,225 | $50.8M | 3.94% | 00.0% | Unchanged |
| VR Adviser, LLC | 1,602,034 | $47.8M | 1.78% | +53,465+3.5% | Added |
| Vanguard Capital Management LLC | 1,435,656 | $42.9M | 0.00% | +1,435,656 | New |
| Alphabet Inc. | 1,388,583 | $41.4M | 1.03% | 00.0% | Unchanged |
| Logos Global Management LP | 1,235,000 | $36.9M | 1.90% | +285,000+30.0% | Added |
| Adage Capital Partners GP, L.L.C. | 1,178,000 | $35.2M | 0.05% | +1,178,000 | New |
| General Catalyst Group Management, LLC | 1,035,910 | $30.9M | 16.85% | 00.0% | Unchanged |
| TRV GP V, LLC | 950,800 | $28.4M | 7.08% | 00.0% | Unchanged |
| FMR LLC | 864,214 | $25.8M | 0.00% | +135,609+18.6% | Added |
| Citadel Advisors LLC | 775,714 | $23.2M | 0.02% | +327,497+73.1% | Added |
| ArrowMark Colorado Holdings LLC | 767,383 | $22.9M | 0.61% | 00.0% | Unchanged |
| Casdin Capital, LLC | 758,857 | $22.7M | 1.72% | 00.0% | Unchanged |
| Cormorant Asset Management, LP | 750,000 | $22.4M | 1.13% | +750,000 | New |
| Woodline Partners LP | 650,229 | $19.4M | 0.07% | −385,000−37.2% | Reduced |
| State Street Corp | 636,722 | $19.0M | 0.00% | +103,717+19.5% | Added |
| Driehaus Capital Management LLC | 636,162 | $19.0M | 0.14% | +258,147+68.3% | Added |
| Caligan Partners LP | 614,962 | $18.4M | 1.30% | +64,771+11.8% | Added |
| Geode Capital Management, LLC | 599,967 | $17.9M | 0.00% | +72,686+13.8% | Added |
| Bessemer Group Inc | 481,790 | $14.4M | 0.02% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 461,151 | $13.8M | 0.03% | +261,939+131.5% | Added |
| Ikarian Capital, LLC | 378,999 | $11.3M | 1.62% | −265,681−41.2% | Reduced |
| Farallon Capital Management, L.L.C. | 373,000 | $11.1M | 0.07% | +373,000 | New |
| HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse) | 366,028 | $10.9M | 0.65% | −91,507−20.0% | Reduced |
| Marshall Wace, LLP | 310,639 | $9.27M | 0.01% | −536,833−63.3% | Reduced |
| Boothbay Fund Management, LLC | 284,476 | $8.49M | 0.20% | −124,896−30.5% | Reduced |
| Washington University | 280,802 | $8.38M | 5.23% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 279,713 | $8.35M | 0.00% | +165,258+144.4% | Added |
| Candriam Luxembourg S.C.A. | 278,167 | $8.30M | 0.04% | +278,167 | New |
| Squadron Capital Management LLC | 257,500 | $7.69M | 3.08% | −232,500−47.4% | Reduced |
| Mass General Brigham, Inc | 239,994 | $7.16M | 1.53% | 00.0% | Unchanged |
| Freestone Grove Partners LP | 234,953 | $7.01M | 0.05% | +116,077+97.6% | Added |
| Sphera Funds Management Ltd. | 227,343 | $6.79M | 1.17% | +155,500+216.4% | Added |
| Standard Life Aberdeen plc | 226,227 | $6.75M | 0.01% | +226,227 | New |
| Northern Trust Corp | 211,382 | $6.31M | 0.00% | +35,123+19.9% | Added |
| Morgan Stanley | 204,831 | $6.11M | 0.00% | −53,255−20.6% | Reduced |
| Spruce Street Capital LP | 200,000 | $5.97M | 1.44% | +200,000 | New |
| Vanguard Portfolio Management LLC | 195,542 | $5.84M | 0.00% | +195,542 | New |
| Bank of America Corp | 195,084 | $5.82M | 0.00% | +176,703+961.3% | Added |
| Charles Schwab Investment Management Inc | 186,433 | $5.57M | 0.00% | +10,464+5.9% | Added |
| Ensign Peak Advisors, Inc | 185,794 | $5.55M | 0.01% | 00.0% | Unchanged |
| Foresite Capital Management IV, LLC | 156,901 | $4.68M | 1.98% | −365,756−70.0% | Reduced |
| Vanguard Fiduciary Trust Co | 151,000 | $4.51M | 0.00% | +151,000 | New |
| Holocene Advisors, LP | 136,168 | $4.06M | 0.01% | +136,168 | New |
| Qube Research & Technologies Ltd | 134,950 | $4.03M | 0.01% | +134,950 | New |
| Price T Rowe Associates Inc | 122,695 | $3.66M | 0.00% | +6,984+6.0% | Added |
| Atika Capital Management LLC | 111,500 | $3.33M | 0.53% | +111,500 | New |
| Ameriprise Financial Inc | 107,486 | $3.21M | 0.00% | +10,798+11.2% | Added |
| Alyeska Investment Group, L.P. | 100,000 | $2.98M | 0.01% | −96,124−49.0% | Reduced |
| Integral Health Asset Management, LLC | 100,000 | $2.98M | 0.16% | 00.0% | Unchanged |
| HighVista Strategies LLC | 99,850 | $2.98M | 0.82% | −70,503−41.4% | Reduced |
| UBS Group AG | 93,898 | $2.80M | 0.00% | +65,200+227.2% | Added |
| Alliancebernstein L.P. | 64,762 | $2.68M | 0.00% | +31,542+94.9% | Added |
| Exome Asset Management LLC | 88,510 | $2.64M | 1.55% | +88,510 | New |
| Invesco Ltd. | 86,419 | $2.58M | 0.00% | −47,614−35.5% | Reduced |
| SummitTX Capital, L.P. | 83,750 | $2.50M | 0.08% | +14,190+20.4% | Added |
| Bank of New York Mellon Corp | 74,268 | $2.22M | 0.00% | +13,832+22.9% | Added |
| Raymond James Financial Inc | 69,375 | $2.07M | 0.00% | +1,657+2.4% | Added |
| Nuveen, LLC | 63,360 | $1.89M | 0.00% | +6,102+10.7% | Added |
| Wellington Management Group LLP | 60,587 | $1.81M | 0.00% | −618−1.0% | Reduced |
| Advisor Group Holdings, Inc. | 59,943 | $1.79M | 0.00% | +181+0.3% | Added |
| Franklin Resources Inc | 59,637 | $1.78M | 0.00% | +4,408+8.0% | Added |
| JPMorgan Chase & Co | 58,446 | $1.70M | 0.00% | +38,439+192.1% | Added |
| ADAR1 Capital Management, LLC | 50,095 | $1.50M | 0.09% | −129,437−72.1% | Reduced |
| D. E. Shaw & Co., Inc. | 45,636 | $1.36M | 0.00% | +11,942+35.4% | Added |
| Propel Bio Management, LLC | 43,798 | $1.31M | 0.82% | +43,798 | New |
| Alps Advisors Inc | 39,171 | $1.17M | 0.01% | +39,171 | New |
| Schroder Investment Management Group | 37,181 | $1.08M | 0.00% | +37,181 | New |
| DAFNA Capital Management LLC | 35,000 | $1.04M | 0.24% | +35,000 | New |
| Aquatic Capital Management LLC | 34,977 | $1.04M | 0.03% | +34,977 | New |
| Russell Investments Group, Ltd. | 32,526 | $970.9K | 0.00% | +9,981+44.3% | Added |
| Parkman Healthcare Partners LLC | 31,844 | $950.5K | 0.10% | −177,422−84.8% | Reduced |
| Rhumbline Advisers | 31,513 | $940.7K | 0.00% | +7,782+32.8% | Added |
| Twinbeech Capital LP | 30,989 | $925.0K | 0.10% | +30,989 | New |
| Seven Fleet Capital Management LP | 30,707 | $916.6K | 0.29% | +30,707 | New |
| Millennium Management LLC | 29,892 | $892.3K | 0.00% | −124,578−80.6% | Reduced |
| AQR Capital Management LLC | 27,945 | $834.2K | 0.00% | +506+1.8% | Added |
| Walleye Capital LLC | 27,945 | $834.2K | 0.01% | +27,945 | New |
| XTX Topco Ltd | 26,854 | $801.6K | 0.01% | −6,167−18.7% | Reduced |
| Foresite Capital Management V, LLC | 25,905 | $773.3K | 0.29% | −60,386−70.0% | Reduced |
| First Trust Advisors LP | 25,485 | $760.7K | 0.00% | +25,485 | New |
| Susquehanna International Group, LLP | 25,301 | $755.2K | 0.00% | +25,301 | New |
| Blackstone Group Inc. | 24,990 | $746.0K | 0.00% | +24,990 | New |
| Y-Intercept (Hong Kong) Ltd | 21,728 | $648.6K | 0.01% | +21,728 | New |
| Deutsche Bank AG | 20,263 | $604.9K | 0.00% | +4,741+30.5% | Added |
| Acuta Capital Partners, LLC | 19,335 | $577.1K | 0.41% | −665−3.3% | Reduced |
| Verition Fund Management LLC | 19,134 | $571.1K | 0.01% | −3,378−15.0% | Reduced |
| Prelude Capital Management, LLC | 18,127 | $541.1K | 0.04% | +18,127 | New |
| Caitong International Asset Management Co., Ltd | 17,783 | $530.8K | 0.10% | +14,282+407.9% | Added |
| Gilder Gagnon Howe & Co LLC | 17,487 | $522.0K | 0.01% | −5,795−24.9% | Reduced |
| Two Sigma Investments, LP | 15,845 | $473.0K | 0.00% | +8,600+118.7% | Added |
| Renaissance Technologies LLC | 15,800 | $471.6K | 0.00% | −11,300−41.7% | Reduced |
| Vanguard Global Advisers, LLC | 15,202 | $453.8K | 0.00% | +15,202 | New |
| Engineers Gate Manager LP | 15,110 | $451.0K | 0.01% | +15,110 | New |