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Maze Therapeutics, Inc.

MAZE
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001842295

In the last 90 days, Maze Therapeutics, Inc. insiders filed 0 open-market purchases and 12 sales; 161 institutions reported holding it in 13F filings for Q2 2026, worth $1.75B in total; HHLR Advisors (Hillhouse) is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Maze Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
143
+49 vs. Q3 2025
Shares held
48.4M
+5.40M (+12.6%) vs. Q3 2025
Total value
$2.00B
+$889.5M (+79.8%) vs. Q3 2025
New holders
57
46 more added
Sold out
8
20 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MAZE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 143 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 68 institutionsQ2 2025: 75 institutionsQ3 2025: 94 institutionsQ4 2025: 143 institutionsQ1 2026: 165 institutionsQ2 2026: 161 institutions
Value heldQ4 2025: $2.00B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $441.4MQ2 2025: $476.7MQ3 2025: $1.11BQ4 2025: $2.00BQ1 2026: $1.54BQ2 2026: $1.75B
Institutions holding MAZE and their total value by quarter
QuarterHoldersValue
Q2 2026161$1.75B
Q1 2026165$1.54B
Q4 2025143$2.00B
Q3 202594$1.11B
Q2 202575$476.7M
Q1 202568$441.4M
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Maze Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding MAZE in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Landscape Capital Management, L.L.C.6,050$250.7K0.02%+6,050New
ProShare Advisors LLC6,047$250.5K0.00%+6,047New
Profund Advisors LLC6,016$249.2K0.01%+6,016New
Police & Firemen's Retirement System of New Jersey5,961$247.0K0.00%+931+18.5%Added
SEI Investments Co5,668$234.8K0.00%+5,668New
BNP Paribas Arbitrage, SA5,473$226.7K0.00%−6,545−54.5%Reduced
CIBC Private Wealth Group, LLC5,400$223.7K0.00%+5,400New
Legal & General Group Plc5,379$222.9K0.00%+160+3.1%Added
Rafferty Asset Management, LLC5,244$217.3K0.00%+5,244New
Quantbot Technologies LP5,221$216.3K0.01%+5,221New
WestHill Financial Advisors, Inc.5,186$214.9K0.04%+5,186New
Brevan Howard Capital Management LP5,042$208.9K0.00%+5,042New
IFP Advisors, Inc3,514$145.6K0.00%+3,514New
Caitong International Asset Management Co., Ltd3,501$145.0K0.04%+3,501New
Mirae Asset Global Investments Co., Ltd.2,338$96.9K0.00%+2,338New
CWM, LLC2,229$92.0K0.00%+91+4.3%Added
Ameritas Investment Partners, Inc.1,632$67.6K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)1,349$55.9K0.00%−663−33.0%Reduced
California State Teachers Retirement System1,321$54.7K0.00%+766+138.0%Added
Sterling Capital Management LLC1,161$48.1K0.00%−99−7.9%Reduced
GF Fund Management Co. Ltd.944$39.1K0.00%+944New
Amalgamated Bank674$28.0K0.00%+369+121.0%Added
Royal Bank of Canada646$27.0K0.00%+363+128.3%Added
Farther Finance Advisors, LLC359$14.9K0.00%−24−6.3%Reduced
Nisa Investment Advisors, LLC204$8.45K0.00%+178+684.6%Added
GAMMA Investing LLC172$7.13K0.00%+13+8.2%Added
Daiwa Securities Group Inc.160$7.00K0.00%+160New
EverSource Wealth Advisors, LLC149$6.17K0.00%00.0%Unchanged
Torren Management, LLC112$4.64K0.00%+112New
UBS Asset Management Americas Inc99$4.10K0.00%+99New
Jones Financial Companies LLLP90$3.73K0.00%+90New
SBI Securities Co., Ltd.67$2.78K0.00%+6+9.8%Added
The PNC Financial Services Group, Inc.58$2.40K0.00%−35−37.6%Reduced
SageView Advisory Group, LLC54$2.24K0.00%+54New
US Bancorp41$1.70K0.00%+41New
Cornerstone Financial Management LLC28$1.16K0.00%+28New
Signaturefd, LLC14$5800.00%+14New
Sunbelt Securities, Inc.12$4970.00%00.0%Unchanged
Rothschild Investment LLC10$4140.00%00.0%Unchanged
Essential Partners LLC7$2900.00%00.0%Unchanged
Rachor Investment Advisory Services, LLC6$2490.00%+6New
True Wealth Design, LLC5$2080.00%00.0%Unchanged
Allworth Financial LP5$2080.00%+5New
Octagon Capital Advisors LP0$00.00%−177,667−100.0%Sold out
Nantahala Capital Management, LLC0$00.00%−93,351−100.0%Sold out
Harvard Management Co Inc0$00.00%−92,396−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−16,165−100.0%Sold out
Winton Group Ltd0$00.00%−14,487−100.0%Sold out
Alps Advisors Inc0$00.00%−13,742−100.0%Sold out
Caption Management, LLC0$00.00%−4,000−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−307−100.0%Sold out