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Lakefront Biotherapeutics NV

LKFT
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001421876

No open-market purchases or sales by Lakefront Biotherapeutics NV insiders were filed in the last 90 days; 76 institutions reported holding it in 13F filings for Q2 2026, worth $960.3M in total; Greenlight Capital is the only superinvestor holding it.

Other share classesGLPGF

13F holders, Q4 2021

Institutional positions in Lakefront Biotherapeutics NV as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
83
+4 vs. Q3 2021
Shares held
10.8M
+2.25M (+26.3%) vs. Q3 2021
Total value
$595.0M
+$145.3M (+32.3%) vs. Q3 2021
New holders
19
32 more added
Sold out
15
23 more reduced

2 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LKFT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 83 institutions
Q1 2021: 133 institutionsQ2 2021: 109 institutionsQ3 2021: 81 institutionsQ4 2021: 83 institutionsQ1 2022: 90 institutionsQ2 2022: 82 institutionsQ3 2022: 84 institutionsQ4 2022: 75 institutionsQ1 2023: 76 institutionsQ2 2023: 76 institutionsQ3 2023: 73 institutionsQ4 2023: 88 institutionsQ1 2024: 83 institutionsQ2 2024: 85 institutionsQ3 2024: 79 institutionsQ4 2024: 82 institutionsQ1 2025: 83 institutionsQ2 2025: 85 institutionsQ3 2025: 92 institutionsQ4 2025: 91 institutionsQ1 2026: 90 institutionsQ2 2026: 76 institutions
Value heldQ4 2021: $595.0M
Q1 2021: $506.0MQ2 2021: $517.2MQ3 2021: $449.8MQ4 2021: $595.0MQ1 2022: $795.8MQ2 2022: $720.0MQ3 2022: $551.1MQ4 2022: $584.8MQ1 2023: $703.8MQ2 2023: $801.4MQ3 2023: $662.4MQ4 2023: $804.5MQ1 2024: $659.6MQ2 2024: $494.0MQ3 2024: $393.4MQ4 2024: $856.9MQ1 2025: $783.2MQ2 2025: $887.2MQ3 2025: $1.09BQ4 2025: $1.03BQ1 2026: $937.9MQ2 2026: $960.3M
Institutions holding LKFT and their total value by quarter
QuarterHoldersValue
Q2 202676$960.3M
Q1 202690$937.9M
Q4 202591$1.03B
Q3 202592$1.09B
Q2 202585$887.2M
Q1 202583$783.2M
Q4 202482$856.9M
Q3 202479$393.4M
Q2 202485$494.0M
Q1 202483$659.6M
Q4 202388$804.5M
Q3 202373$662.4M
Q2 202376$801.4M
Q1 202376$703.8M
Q4 202275$584.8M
Q3 202284$551.1M
Q2 202282$720.0M
Q1 202290$795.8M
Q4 202183$595.0M
Q3 202181$449.8M
Q2 2021109$517.2M
Q1 2021133$506.0M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Lakefront Biotherapeutics NV; share changes are against Q3 2021.

Institutions holding LKFT in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
EcoR1 Capital, LLC2,224,403$122.6M3.93%+665,654+42.7%Added
BVF Inc1,156,393$63.8M2.31%+36,660+3.3%Added
683 Capital Management, LLC905,121$49.9M2.38%+203,700+29.0%Added
Point72 Asset Management, L.P.763,900$42.1M0.19%+646,000+547.9%Added
OrbiMed Advisors LLC717,257$39.5M0.51%−6,200−0.9%Reduced
Citadel Advisors LLC520,188$28.7M0.03%+19,970+4.0%Added
BlackRock Inc.352,699$19.4M0.00%−37,060−9.5%Reduced
Prosight Management, LP345,900$19.1M12.70%+95,220+38.0%Added
Great Point Partners LLC300,000$16.5M3.70%+300,000New
JPMorgan Chase & Co292,487$16.1M0.00%+220+0.1%Added
Sio Capital Management, LLC261,377$14.4M4.39%+36,658+16.3%Added
Millennium Management LLC234,180$12.9M0.01%+23,535+11.2%Added
Greenlight Capital Inc185,000$10.2M0.62%+185,000New
LMR Partners LLP176,880$9.75M0.13%+76,880+76.9%Added
Paradigm Biocapital Advisors LP167,824$9.25M2.64%+167,824New
Hudson Bay Capital Management LP145,000$7.99M0.09%−10,000−6.5%Reduced
D. E. Shaw & Co., Inc.137,340$7.57M0.01%+539+0.4%Added
Silverarc Capital Management, LLC128,901$7.11M3.18%+128,901New
Norges Bank120,000$6.62M0.00%00.0%Unchanged
Morgan Stanley101,375$5.59M0.00%−40,951−28.8%Reduced
Soleus Capital Management, L.P.98,800$5.45M0.74%−16,500−14.3%Reduced
Monaco Asset Management SAM97,064$5.35M3.35%+97,064New
Ikarian Capital, LLC86,865$4.86M1.39%00.0%Unchanged
Sessa Capital IM, L.P.82,000$4.52M0.24%00.0%Unchanged
Alps Advisors Inc76,280$4.21M0.05%+76,280New
Goldman Sachs Group Inc76,185$4.20M0.00%+13,100+20.8%Added
Brookfield Asset Management Inc.66,805$3.68M0.01%+66,805New
UBS Group AG66,202$3.65M0.00%+65,334+7,527.0%Added
Renaissance Technologies LLC56,600$3.12M0.00%+5,700+11.2%Added
FMR LLC49,501$2.73M0.00%−37,739−43.3%Reduced
Susquehanna International Group, LLP49,406$2.72M0.00%−77,392−61.0%Reduced
Voloridge Investment Management, LLC49,002$2.70M0.01%−38,226−43.8%Reduced
Schonfeld Strategic Advisors LLC43,426$2.39M0.02%+43,426New
DAFNA Capital Management LLC42,675$2.35M0.59%−35,000−45.1%Reduced
Carlson Capital L P40,000$2.21M0.13%+40,000New
Bank of America Corp39,012$2.15M0.00%+30,269+346.2%Added
Bluefin Capital Management, LLC38,065$2.10M0.17%+24,325+177.0%Added
Cubist Systematic Strategies, LLC36,534$2.01M0.02%−5,189−12.4%Reduced
ExodusPoint Capital Management, LP36,372$2.00M0.02%+16,294+81.2%Added
Optiver Holding B.V.32,206$1.71M0.00%+6,149+23.6%Added
AlphaCentric Advisors LLC31,000$1.71M0.50%+1,500+5.1%Added
Caption Management, LLC30,000$1.65M0.10%+30,000New
Cinctive Capital Management LP28,100$1.55M0.07%+28,100New
J. Goldman & Co LP27,972$1.54M0.14%+27,972New
Parallax Volatility Advisers, L.P.26,800$1.48M0.02%−191,124−87.7%Reduced
New York Life Investments Alternatives25,978$1.43M0.96%+6,711+34.8%Added
Eqis Capital Management, Inc.23,621$1.30M0.10%+1,426+6.4%Added
Prelude Capital Management, LLC22,505$1.24M0.06%+22,505New
HAP Trading, LLC22,218$1.23M0.09%−6,361−22.3%Reduced
Alliancebernstein L.P.20,000$1.10M0.00%+20,000New
Wellington Management Group LLP16,282$898.0K0.00%+16,282New
Two Sigma Advisers, LP14,400$794.0K0.00%−700−4.6%Reduced
Capital International Inc10,653$587.0K0.01%−16,740−61.1%Reduced
Boothbay Fund Management, LLC8,756$483.0K0.02%−1,429−14.0%Reduced
Barclays PLC8,261$455.0K0.00%00.0%Unchanged
Cutler Group LP7,800$430.0K0.03%−21,920−73.8%Reduced
CSS LLC7,458$411.0K0.02%+1,694+29.4%Added
Quantbot Technologies LP7,465$411.0K0.03%+1,752+30.7%Added
Citigroup Inc7,328$404.0K0.00%−779−9.6%Reduced
Knott David M Jr7,000$386.0K0.15%+7,000New
Gabelli Funds LLC6,500$358.0K0.00%−500−7.1%Reduced
Marshall Wace, LLP6,225$344.0K0.00%+6,225New
Geode Capital Management, LLC6,112$336.0K0.00%+2,085+51.8%Added
King Wealth6,000$331.0K0.06%00.0%Unchanged
Jane Street Group, LLC3,719$205.0K0.00%−2,133−36.4%Reduced
Royal Bank of Canada3,415$189.0K0.00%+233+7.3%Added
Aquatic Capital Management LLC2,000$110.0K0.21%+2,000New
US Bancorp1,414$78.0K0.00%+733+107.6%Added
Advisor Group Holdings, Inc.1,226$68.0K0.00%+467+61.5%Added
Cacti Asset Management LLC1,000$55.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)807$44.0K0.00%−2,772−77.5%Reduced
Signaturefd, LLC505$28.0K0.00%+264+109.5%Added
Quadrant Capital Group LLC383$21.0K0.00%+188+96.4%Added
Atlas Capital Advisors LLC348$19.2K0.00%−700−66.8%Reduced
Pacer Advisors, Inc.280$15.0K0.00%−140−33.3%Reduced
Captrust Financial Advisors220$12.0K0.00%00.0%Unchanged
Lindbrook Capital, LLC213$12.0K0.00%+8+3.9%Added
Wells Fargo & Company135$8.00K0.00%−219−61.9%Reduced
Parallel Advisors, LLC48$3.00K0.00%+32+200.0%Added
Daiwa Securities Group Inc.32$2.00K0.00%00.0%Unchanged
Bedel Financial Consulting, Inc.25$1.00K0.00%00.0%Unchanged
CWM, LLC8$00.00%+8New
Sofos Investments, Inc.1,815––+1,738+2,257.1%Added
Stonepine Capital Management, LLC0$00.00%−244,205−100.0%Sold out
Canada Pension Plan Investment Board0$00.00%−57,100−100.0%Sold out
HRT Financial LP0$00.00%−39,608−100.0%Sold out
Jump Financial, LLC0$00.00%−29,817−100.0%Sold out
Susquehanna Fundamental Investments, LLC0$00.00%−28,551−100.0%Sold out
Affinity Asset Advisors, LLC0$00.00%−20,000−100.0%Sold out
PointState Capital LP0$00.00%−17,500−100.0%Sold out
Continental Advisors LLC0$00.00%−10,000−100.0%Sold out
DekaBank Deutsche Girozentrale0$00.00%−2,760−100.0%Sold out
Group One Trading, L.P.0$00.00%−2,368−100.0%Sold out
Erste Asset Management GmbH0$00.00%−1,700−100.0%Sold out
Harbour Investments, Inc.0$00.00%−408−100.0%Sold out
Penserra Capital Management LLC0$00.00%−215−100.0%Sold out
Assetmark, Inc0$00.00%−171−100.0%Sold out
Arkadios Wealth Advisors0$00.00%−29−100.0%Sold out
Knott David M––––Not filed
Wealth Quarterback LLC––––Not filed