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Lakefront Biotherapeutics NV

LKFT
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001421876

No open-market purchases or sales by Lakefront Biotherapeutics NV insiders were filed in the last 90 days; 76 institutions reported holding it in 13F filings for Q2 2026, worth $960.3M in total; Greenlight Capital is the only superinvestor holding it.

Other share classesGLPGF

13F holders, Q1 2022

Institutional positions in Lakefront Biotherapeutics NV as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
90
+8 vs. Q4 2021
Shares held
12.8M
+2.07M (+19.2%) vs. Q4 2021
Total value
$795.8M
+$202.5M (+34.1%) vs. Q4 2021
New holders
24
24 more added
Sold out
16
31 more reduced

1 institution that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LKFT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 90 institutions
Q1 2021: 133 institutionsQ2 2021: 109 institutionsQ3 2021: 81 institutionsQ4 2021: 83 institutionsQ1 2022: 90 institutionsQ2 2022: 82 institutionsQ3 2022: 84 institutionsQ4 2022: 75 institutionsQ1 2023: 76 institutionsQ2 2023: 76 institutionsQ3 2023: 73 institutionsQ4 2023: 88 institutionsQ1 2024: 83 institutionsQ2 2024: 85 institutionsQ3 2024: 79 institutionsQ4 2024: 82 institutionsQ1 2025: 83 institutionsQ2 2025: 85 institutionsQ3 2025: 92 institutionsQ4 2025: 91 institutionsQ1 2026: 90 institutionsQ2 2026: 76 institutions
Value heldQ1 2022: $795.8M
Q1 2021: $506.0MQ2 2021: $517.2MQ3 2021: $449.8MQ4 2021: $595.0MQ1 2022: $795.8MQ2 2022: $720.0MQ3 2022: $551.1MQ4 2022: $584.8MQ1 2023: $703.8MQ2 2023: $801.4MQ3 2023: $662.4MQ4 2023: $804.5MQ1 2024: $659.6MQ2 2024: $494.0MQ3 2024: $393.4MQ4 2024: $856.9MQ1 2025: $783.2MQ2 2025: $887.2MQ3 2025: $1.09BQ4 2025: $1.03BQ1 2026: $937.9MQ2 2026: $960.3M
Institutions holding LKFT and their total value by quarter
QuarterHoldersValue
Q2 202676$960.3M
Q1 202690$937.9M
Q4 202591$1.03B
Q3 202592$1.09B
Q2 202585$887.2M
Q1 202583$783.2M
Q4 202482$856.9M
Q3 202479$393.4M
Q2 202485$494.0M
Q1 202483$659.6M
Q4 202388$804.5M
Q3 202373$662.4M
Q2 202376$801.4M
Q1 202376$703.8M
Q4 202275$584.8M
Q3 202284$551.1M
Q2 202282$720.0M
Q1 202290$795.8M
Q4 202183$595.0M
Q3 202181$449.8M
Q2 2021109$517.2M
Q1 2021133$506.0M

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Lakefront Biotherapeutics NV; share changes are against Q4 2021.

Institutions holding LKFT in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
EcoR1 Capital, LLC3,195,624$198.2M6.21%+971,221+43.7%Added
FMR LLC2,166,959$134.4M0.01%+2,117,458+4,277.6%Added
BVF Inc1,046,283$64.9M2.60%−110,110−9.5%Reduced
BlackRock Inc.517,611$32.1M0.00%+164,912+46.8%Added
Point72 Asset Management, L.P.509,800$31.6M0.14%−254,100−33.3%Reduced
683 Capital Management, LLC486,000$30.1M1.78%−419,121−46.3%Reduced
Driehaus Capital Management LLC477,615$29.6M0.36%+477,615New
Prosight Management, LP374,000$23.2M16.33%+28,100+8.1%Added
Great Point Partners LLC360,000$22.3M5.40%+60,000+20.0%Added
Millennium Management LLC315,131$19.5M0.02%+80,951+34.6%Added
JPMorgan Chase & Co299,710$18.6M0.00%+7,223+2.5%Added
Deutsche Bank AG294,207$18.2M0.01%+294,207New
Tang Capital Management LLC250,000$15.5M3.14%+250,000New
Avidity Partners Management LP215,000$13.3M0.30%+215,000New
OrbiMed Advisors LLC208,225$12.9M0.21%−509,032−71.0%Reduced
Greenlight Capital Inc160,200$9.94M0.63%−24,800−13.4%Reduced
Bridger Management, LLC153,700$9.53M1.56%+153,700New
Morgan Stanley151,014$9.37M0.00%+49,639+49.0%Added
Sio Capital Management, LLC146,696$9.10M3.67%−114,681−43.9%Reduced
Norges Bank120,000$7.44M0.00%00.0%Unchanged
Newtyn Management, LLC113,400$7.03M1.68%+113,400New
Ikarian Capital, LLC86,865$5.41M1.65%00.0%Unchanged
Renaissance Technologies LLC84,500$5.24M0.01%+27,900+49.3%Added
Sessa Capital IM, L.P.82,000$5.09M0.31%00.0%Unchanged
Alps Advisors Inc67,162$4.17M0.05%−9,118−12.0%Reduced
Citadel Advisors LLC64,992$4.03M0.00%−455,196−87.5%Reduced
Goldman Sachs Group Inc62,998$3.91M0.00%−13,187−17.3%Reduced
Endurant Capital Management LP52,400$3.25M0.98%+52,400New
Schonfeld Strategic Advisors LLC51,082$3.17M0.04%+7,656+17.6%Added
LMR Partners LLP49,748$3.08M0.05%−127,132−71.9%Reduced
Cubist Systematic Strategies, LLC45,845$2.84M0.02%+9,311+25.5%Added
D. E. Shaw & Co., Inc.43,215$2.68M0.00%−94,125−68.5%Reduced
DAFNA Capital Management LLC42,675$2.65M0.69%00.0%Unchanged
Silverarc Capital Management, LLC41,002$2.54M1.38%−87,899−68.2%Reduced
Cinctive Capital Management LP38,100$2.36M0.11%+10,000+35.6%Added
Carlson Capital L P35,000$2.17M0.15%−5,000−12.5%Reduced
Hudson Bay Capital Management LP32,500$2.02M0.03%−112,500−77.6%Reduced
Arrowstreet Capital, Limited Partnership31,986$1.98M0.00%+31,986New
Bluefin Capital Management, LLC30,273$1.88M0.33%−7,792−20.5%Reduced
Prelude Capital Management, LLC29,760$1.85M0.09%+7,255+32.2%Added
New York Life Investments Alternatives27,603$1.71M1.19%+1,625+6.3%Added
HealthCor Management, L.P.23,740$1.47M0.10%+23,740New
Barclays PLC19,772$1.23M0.00%+11,511+139.3%Added
Jane Street Group, LLC18,579$1.15M0.00%+14,860+399.6%Added
Monaco Asset Management SAM17,000$1.05M0.56%−80,064−82.5%Reduced
Wellington Management Group LLP16,575$1.03M0.00%+293+1.8%Added
Parametric Portfolio Associates LLC13,664$847.0K0.00%+13,664New
HighVista Strategies LLC13,209$819.0K0.52%+13,209New
Susquehanna International Group, LLP13,013$807.0K0.00%−36,393−73.7%Reduced
Optiver Holding B.V.11,459$711.0K0.00%−20,747−64.4%Reduced
Calamos Advisors LLC10,555$655.0K0.00%+10,555New
Connective Portfolio Management, LLC10,000$643.0K1.42%+10,000New
Wells Fargo & Company8,956$556.0K0.00%+8,821+6,534.1%Added
Boothbay Fund Management, LLC8,756$543.0K0.02%00.0%Unchanged
Two Sigma Advisers, LP7,800$484.0K0.00%−6,600−45.8%Reduced
American Century Companies Inc6,707$416.0K0.00%+6,707New
Gabelli Funds LLC6,500$403.0K0.00%00.0%Unchanged
Geode Capital Management, LLC6,107$378.0K0.00%−5−0.1%Reduced
Caption Management, LLC6,000$373.0K0.02%−24,000−80.0%Reduced
King Wealth6,000$372.0K0.07%00.0%Unchanged
Ergoteles LLC5,971$370.0K0.01%+5,971New
Citigroup Inc5,950$369.0K0.00%−1,378−18.8%Reduced
Bank of America Corp5,268$326.0K0.00%−33,744−86.5%Reduced
Dimensional Fund Advisors LP4,027$250.0K0.00%+4,027New
State Street Corp3,898$242.0K0.00%+3,898New
Royal Bank of Canada3,097$192.0K0.00%−318−9.3%Reduced
Cutler Group LP3,034$188.0K0.02%−4,766−61.1%Reduced
US Bancorp2,596$161.0K0.00%+1,182+83.6%Added
Tower Research Capital LLC (TRC)2,515$156.0K0.00%+1,708+211.6%Added
Simplex Trading, LLC1,994$123.0K0.00%+1,994New
Cacti Asset Management LLC1,000$62.0K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.820$52.0K0.00%−406−33.1%Reduced
UBS Group AG806$50.0K0.00%−65,396−98.8%Reduced
Quantbot Technologies LP700$43.0K0.00%−6,765−90.6%Reduced
Group One Trading, L.P.642$40.0K0.00%+642New
Zurcher Kantonalbank (Zurich Cantonalbank)547$34.0K0.00%+547New
Signaturefd, LLC489$30.0K0.00%−16−3.2%Reduced
Quadrant Capital Group LLC435$27.0K0.00%+52+13.6%Added
Acadian Asset Management LLC412$25.0K0.00%+412New
Captrust Financial Advisors378$23.0K0.00%+158+71.8%Added
Atlas Capital Advisors LLC348$21.6K0.00%00.0%Unchanged
Lindbrook Capital, LLC282$17.0K0.00%+69+32.4%Added
Aquatic Capital Management LLC200$12.0K0.02%−1,800−90.0%Reduced
IFP Advisors, Inc74$8.00K0.00%+74New
Parallel Advisors, LLC66$4.00K0.00%+18+37.5%Added
AdvisorNet Financial, Inc54$3.00K0.00%+54New
Daiwa Securities Group Inc.32$2.00K0.00%00.0%Unchanged
CWM, LLC8$00.00%00.0%Unchanged
Money Concepts Capital Corp2$00.00%+2New
Sofos Investments, Inc.248––−1,567−86.3%Reduced
Paradigm Biocapital Advisors LP0$00.00%−167,824−100.0%Sold out
Soleus Capital Management, L.P.0$00.00%−98,800−100.0%Sold out
Brookfield Asset Management Inc.0$00.00%−66,805−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−49,002−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−36,372−100.0%Sold out
J. Goldman & Co LP0$00.00%−27,972−100.0%Sold out
Parallax Volatility Advisers, L.P.0$00.00%−26,800−100.0%Sold out
Eqis Capital Management, Inc.0$00.00%−23,621−100.0%Sold out
HAP Trading, LLC0$00.00%−22,218−100.0%Sold out
Alliancebernstein L.P.0$00.00%−20,000−100.0%Sold out