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Lakefront Biotherapeutics NV

LKFT
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001421876

No open-market purchases or sales by Lakefront Biotherapeutics NV insiders were filed in the last 90 days; 76 institutions reported holding it in 13F filings for Q2 2026, worth $960.3M in total; Greenlight Capital is the only superinvestor holding it.

Other share classesGLPGF

13F holders, Q3 2025

Institutional positions in Lakefront Biotherapeutics NV as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
92
+8 vs. Q2 2025
Shares held
31.4M
−176.5K (−0.6%) vs. Q2 2025
Total value
$1.09B
+$203.9M (+23.1%) vs. Q2 2025
New holders
18
31 more added
Sold out
10
29 more reduced

1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LKFT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 92 institutions
Q1 2021: 133 institutionsQ2 2021: 109 institutionsQ3 2021: 81 institutionsQ4 2021: 83 institutionsQ1 2022: 90 institutionsQ2 2022: 82 institutionsQ3 2022: 84 institutionsQ4 2022: 75 institutionsQ1 2023: 76 institutionsQ2 2023: 76 institutionsQ3 2023: 73 institutionsQ4 2023: 88 institutionsQ1 2024: 83 institutionsQ2 2024: 85 institutionsQ3 2024: 79 institutionsQ4 2024: 82 institutionsQ1 2025: 83 institutionsQ2 2025: 85 institutionsQ3 2025: 92 institutionsQ4 2025: 91 institutionsQ1 2026: 90 institutionsQ2 2026: 76 institutions
Value heldQ3 2025: $1.09B
Q1 2021: $506.0MQ2 2021: $517.2MQ3 2021: $449.8MQ4 2021: $595.0MQ1 2022: $795.8MQ2 2022: $720.0MQ3 2022: $551.1MQ4 2022: $584.8MQ1 2023: $703.8MQ2 2023: $801.4MQ3 2023: $662.4MQ4 2023: $804.5MQ1 2024: $659.6MQ2 2024: $494.0MQ3 2024: $393.4MQ4 2024: $856.9MQ1 2025: $783.2MQ2 2025: $887.2MQ3 2025: $1.09BQ4 2025: $1.03BQ1 2026: $937.9MQ2 2026: $960.3M
Institutions holding LKFT and their total value by quarter
QuarterHoldersValue
Q2 202676$960.3M
Q1 202690$937.9M
Q4 202591$1.03B
Q3 202592$1.09B
Q2 202585$887.2M
Q1 202583$783.2M
Q4 202482$856.9M
Q3 202479$393.4M
Q2 202485$494.0M
Q1 202483$659.6M
Q4 202388$804.5M
Q3 202373$662.4M
Q2 202376$801.4M
Q1 202376$703.8M
Q4 202275$584.8M
Q3 202284$551.1M
Q2 202282$720.0M
Q1 202290$795.8M
Q4 202183$595.0M
Q3 202181$449.8M
Q2 2021109$517.2M
Q1 2021133$506.0M

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Lakefront Biotherapeutics NV; share changes are against Q2 2025.

Institutions holding LKFT in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Gilead Sciences, Inc.16,707,477$578.7M32.31%00.0%Unchanged
Tang Capital Management LLC4,151,194$143.8M5.54%+161,083+4.0%Added
Madison Avenue Partners, LP2,195,775$76.1M4.54%+318,764+17.0%Added
EcoR1 Capital, LLC1,667,119$57.7M2.78%+630,174+60.8%Added
Ameriprise Financial Inc1,416,934$49.1M0.01%+1,362,229+2,490.1%Added
Prosight Management, LP1,150,000$39.8M9.56%−623,649−35.2%Reduced
Segall Bryant & Hamill, LLC487,196$16.9M0.22%−13,881−2.8%Reduced
DME Capital Management, LPSuperinvestorGreenlight Capital482,746$16.7M0.66%00.0%Unchanged
Point72 Asset Management, L.P.443,869$15.4M0.03%+102,369+30.0%Added
Renaissance Technologies LLC356,200$12.3M0.02%−108,500−23.3%Reduced
Hudson Bay Capital Management LP245,000$8.49M0.05%−270,000−52.4%Reduced
BlackRock, Inc.239,843$8.31M0.00%+13,787+6.1%Added
D. E. Shaw & Co., Inc.201,169$6.97M0.01%+47,984+31.3%Added
UBS Group AG152,999$5.30M0.00%−85,525−35.9%Reduced
Millennium Management LLC152,902$5.30M0.00%−37,807−19.8%Reduced
DAFNA Capital Management LLC130,175$4.51M1.11%00.0%Unchanged
Cubist Systematic Strategies, LLC104,539$3.62M0.05%+92,168+745.0%Added
Voloridge Investment Management, LLC87,572$3.03M0.01%+2,171+2.5%Added
Goldman Sachs Group Inc66,141$2.29M0.00%+9,410+16.6%Added
Morgan Stanley64,063$2.22M0.00%−2,101−3.2%Reduced
FMR LLC54,011$1.87M0.00%−1,493,017−96.5%Reduced
Jump Financial, LLC51,300$1.78M0.02%+26,570+107.4%Added
Primecap Management Co50,500$1.75M0.00%−92,810−64.8%Reduced
Matauro, LLC47,536$1.65M0.26%+47,536New
Barclays PLC39,002$1.35M0.00%−1,167−2.9%Reduced
Marshall Wace, LLP38,460$1.33M0.00%+38,460New
Suvretta Capital Management, LLC37,111$1.29M0.04%00.0%Unchanged
Man Group plc36,197$1.25M0.00%+36,197New
Monaco Asset Management SAM33,536$1.16M0.43%−2,500−6.9%Reduced
Crossmark Global Holdings, Inc.32,897$1.14M0.02%−14,545−30.7%Reduced
Alps Advisors Inc31,905$1.11M0.01%−3,473−9.8%Reduced
Bank of America Corp30,949$1.07M0.00%+643+2.1%Added
Royal Bank of Canada28,429$984.0K0.00%−52,433−64.8%Reduced
Barometer Capital Management Inc.27,617$956.7K0.22%+10,700+63.2%Added
American Century Companies Inc27,603$956.2K0.00%−499−1.8%Reduced
Quadrature Capital Ltd26,245$909.1K0.01%+26,245New
Two Sigma Investments, LP22,459$778.0K0.00%+800+3.7%Added
Moody National Bank Trust Division20,849$722.2K0.06%00.0%Unchanged
Verition Fund Management LLC20,270$702.2K0.00%−11,043−35.3%Reduced
Prelude Capital Management, LLC19,327$669.5K0.05%+22+0.1%Added
Aquatic Capital Management LLC17,516$606.8K0.01%+6,807+63.6%Added
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management17,469$605.1K0.01%+8,157+87.6%Added
Citadel Advisors LLC15,969$553.2K0.00%+4,262+36.4%Added
QRG Capital Management, Inc.15,093$522.8K0.01%−30.0%Reduced
National Bank of Canada14,281$493.5K0.00%+14,281New
Erste Asset Management GmbH14,000$482.0K0.00%00.0%Unchanged
Citigroup Inc13,853$479.9K0.00%+13,077+1,685.2%Added
XTX Topco Ltd12,057$417.7K0.02%−27,746−69.7%Reduced
BNP Paribas Arbitrage, SA11,854$410.6K0.00%+5,305+81.0%Added
Jane Street Group, LLC9,049$313.5K0.00%−21,726−70.6%Reduced
Commonwealth Equity Services, LLC8,848$306.0K0.00%+466+5.6%Added
Two Sigma Advisers, LP8,700$301.4K0.00%+1,200+16.0%Added
HRT Financial LP8,697$301.0K0.00%+8,697New
Geode Capital Management, LLC7,851$272.0K0.00%00.0%Unchanged
Brinker Capital Investments, LLC7,261$251.5K0.00%+7,261New
Ascent Group, LLC6,313$218.7K0.01%+6,313New
JustInvest LLC6,106$211.5K0.00%+6,106New
Squarepoint Ops LLC6,099$211.3K0.00%+6,099New
Quadrant Capital Group LLC3,880$134.4K0.00%+3,880New
Rhumbline Advisers3,600$124.7K0.00%−255−6.6%Reduced
China Universal Asset Management Co., Ltd.2,511$87.0K0.01%−465−15.6%Reduced
Signaturefd, LLC1,840$63.7K0.00%+275+17.6%Added
GAMMA Investing LLC1,473$51.0K0.00%+652+79.4%Added
Van Eck Associates Corp1,218$42.0K0.00%+107+9.6%Added
Cacti Asset Management LLC1,000$33.8K0.00%00.0%Unchanged
State of Wyoming956$33.1K0.00%−62−6.1%Reduced
Advisor Group Holdings, Inc.625$21.5K0.00%+278+80.1%Added
Tower Research Capital LLC (TRC)597$20.7K0.00%−78,538−99.2%Reduced
SRS Capital Advisors, Inc.557$19.3K0.00%+124+28.6%Added
Mirae Asset Global Investments Co., Ltd.554$19.2K0.00%−18−3.1%Reduced
EverSource Wealth Advisors, LLC309$10.7K0.00%−99−24.3%Reduced
GF Fund Management Co. Ltd.305$10.6K0.00%−52−14.6%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)281$9.73K0.00%−128−31.3%Reduced
Simplex Trading, LLC254$8.00K0.00%+254New
Principal Securities, Inc.184$6.37K0.00%−2−1.1%Reduced
Allworth Financial LP183$6.34K0.00%+48+35.6%Added
Larson Financial Group LLC156$5.40K0.00%+96+160.0%Added
Parallel Advisors, LLC153$5.30K0.00%+50+48.5%Added
US Bancorp94$3.26K0.00%00.0%Unchanged
JPMorgan Chase & Co71$2.46K0.00%+71New
Daiwa Securities Group Inc.51$2.00K0.00%00.0%Unchanged
MAI Capital Management52$1.80K0.00%00.0%Unchanged
Crewe Advisors LLC46$1.59K0.00%+46New
Assetmark, Inc42$1.46K0.00%+30+250.0%Added
Rockefeller Capital Management L.P.35$1.21K0.00%+35New
The PNC Financial Services Group, Inc.26$9010.00%−3−10.3%Reduced
UMA Financial Services, Inc.24$8320.00%+24New
TD Private Client Wealth LLC24$8310.00%00.0%Unchanged
Ronald Blue Trust, Inc.10$3460.00%00.0%Unchanged
GWM Advisors LLC6$2080.00%00.0%Unchanged
Montag A & Associates Inc6$2080.00%+6New
Farther Finance Advisors, LLC1$350.00%+1New
Centiva Capital, LP0$00.00%−94,905−100.0%Sold out
Optiver Holding B.V.0$00.00%−78,929−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−21,866−100.0%Sold out
Engineers Gate Manager LP0$00.00%−19,990−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−15,183−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−8,538−100.0%Sold out
Clear Street Markets LLC0$00.00%−8,234−100.0%Sold out
Headlands Technologies LLC0$00.00%−7,973−100.0%Sold out