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Lakefront Biotherapeutics NV

LKFT
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001421876

No open-market purchases or sales by Lakefront Biotherapeutics NV insiders were filed in the last 90 days; 76 institutions reported holding it in 13F filings for Q2 2026, worth $960.3M in total; Greenlight Capital is the only superinvestor holding it.

Other share classesGLPGF

13F holders, Q2 2025

Institutional positions in Lakefront Biotherapeutics NV as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
85
+3 vs. Q1 2025
Shares held
31.7M
+507.6K (+1.6%) vs. Q1 2025
Total value
$887.2M
+$104.0M (+13.3%) vs. Q1 2025
New holders
21
25 more added
Sold out
18
24 more reduced

1 institution that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LKFT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 85 institutions
Q1 2021: 133 institutionsQ2 2021: 109 institutionsQ3 2021: 81 institutionsQ4 2021: 83 institutionsQ1 2022: 90 institutionsQ2 2022: 82 institutionsQ3 2022: 84 institutionsQ4 2022: 75 institutionsQ1 2023: 76 institutionsQ2 2023: 76 institutionsQ3 2023: 73 institutionsQ4 2023: 88 institutionsQ1 2024: 83 institutionsQ2 2024: 85 institutionsQ3 2024: 79 institutionsQ4 2024: 82 institutionsQ1 2025: 83 institutionsQ2 2025: 85 institutionsQ3 2025: 92 institutionsQ4 2025: 91 institutionsQ1 2026: 90 institutionsQ2 2026: 76 institutions
Value heldQ2 2025: $887.2M
Q1 2021: $506.0MQ2 2021: $517.2MQ3 2021: $449.8MQ4 2021: $595.0MQ1 2022: $795.8MQ2 2022: $720.0MQ3 2022: $551.1MQ4 2022: $584.8MQ1 2023: $703.8MQ2 2023: $801.4MQ3 2023: $662.4MQ4 2023: $804.5MQ1 2024: $659.6MQ2 2024: $494.0MQ3 2024: $393.4MQ4 2024: $856.9MQ1 2025: $783.2MQ2 2025: $887.2MQ3 2025: $1.09BQ4 2025: $1.03BQ1 2026: $937.9MQ2 2026: $960.3M
Institutions holding LKFT and their total value by quarter
QuarterHoldersValue
Q2 202676$960.3M
Q1 202690$937.9M
Q4 202591$1.03B
Q3 202592$1.09B
Q2 202585$887.2M
Q1 202583$783.2M
Q4 202482$856.9M
Q3 202479$393.4M
Q2 202485$494.0M
Q1 202483$659.6M
Q4 202388$804.5M
Q3 202373$662.4M
Q2 202376$801.4M
Q1 202376$703.8M
Q4 202275$584.8M
Q3 202284$551.1M
Q2 202282$720.0M
Q1 202290$795.8M
Q4 202183$595.0M
Q3 202181$449.8M
Q2 2021109$517.2M
Q1 2021133$506.0M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Lakefront Biotherapeutics NV; share changes are against Q1 2025.

Institutions holding LKFT in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Gilead Sciences, Inc.16,707,477$467.6M36.53%00.0%Unchanged
Tang Capital Management LLC3,990,111$111.7M5.65%+28,314+0.7%Added
Madison Avenue Partners, LP1,877,011$52.5M3.51%+1,877,011New
Prosight Management, LP1,773,649$49.6M12.11%+458,751+34.9%Added
FMR LLC1,547,028$43.3M0.00%−9,828−0.6%Reduced
EcoR1 Capital, LLC1,036,945$29.0M1.72%+881,939+569.0%Added
Hudson Bay Capital Management LP515,000$14.4M0.09%−50,000−8.8%Reduced
Segall Bryant & Hamill, LLC501,077$14.0M0.20%−150,384−23.1%Reduced
DME Capital Management, LPSuperinvestorGreenlight Capital482,746$13.5M0.58%00.0%Unchanged
Renaissance Technologies LLC464,700$13.0M0.02%+133,900+40.5%Added
Point72 Asset Management, L.P.341,500$9.56M0.02%+341,500New
UBS Group AG238,524$6.68M0.00%+129,513+118.8%Added
BlackRock, Inc.226,056$6.33M0.00%−27,895−11.0%Reduced
Millennium Management LLC190,709$5.34M0.00%+127,645+202.4%Added
D. E. Shaw & Co., Inc.153,185$4.29M0.00%+90,165+143.1%Added
Primecap Management Co143,310$4.01M0.00%−3,900−2.6%Reduced
DAFNA Capital Management LLC130,175$3.64M1.01%00.0%Unchanged
Norges Bank120,000$3.36M0.00%00.0%Unchanged
Centiva Capital, LP94,905$2.66M0.18%+56,354+146.2%Added
Voloridge Investment Management, LLC85,401$2.39M0.01%+85,401New
Royal Bank of Canada80,862$2.26M0.00%+79,980+9,068.0%Added
Tower Research Capital LLC (TRC)79,135$2.21M0.06%+77,750+5,613.7%Added
Optiver Holding B.V.78,929$2.21M0.06%+48,521+159.6%Added
Morgan Stanley66,164$1.85M0.00%+40,757+160.4%Added
Goldman Sachs Group Inc56,731$1.59M0.00%+56,731New
Ameriprise Financial Inc54,705$1.53M0.00%−9,995−15.4%Reduced
Crossmark Global Holdings, Inc.47,442$1.33M0.02%−1,890−3.8%Reduced
Barclays PLC40,169$1.12M0.00%+8,309+26.1%Added
XTX Topco Ltd39,803$1.11M0.05%+39,803New
Suvretta Capital Management, LLC37,111$1.04M0.04%00.0%Unchanged
Monaco Asset Management SAM36,036$1.01M0.38%00.0%Unchanged
Alps Advisors Inc35,378$990.2K0.01%−12,908−26.7%Reduced
Verition Fund Management LLC31,313$876.5K0.01%+1,238+4.1%Added
Jane Street Group, LLC30,775$861.4K0.00%−80,008−72.2%Reduced
Bank of America Corp30,306$848.3K0.00%−29,300−49.2%Reduced
American Century Companies Inc28,102$786.6K0.00%+263+0.9%Added
Jump Financial, LLC24,730$692.2K0.01%+24,730New
Boothbay Fund Management, LLC21,866$612.0K0.02%+21,866New
Two Sigma Investments, LP21,659$606.2K0.00%−27,502−55.9%Reduced
Moody National Bank Trust Division20,849$583.6K0.05%−5,291−20.2%Reduced
Engineers Gate Manager LP19,990$559.5K0.01%+19,990New
Prelude Capital Management, LLC19,305$540.3K0.05%00.0%Unchanged
Barometer Capital Management Inc.16,917$473.5K0.13%+3,400+25.2%Added
Susquehanna International Group, LLP15,183$425.0K0.00%−7,729−33.7%Reduced
QRG Capital Management, Inc.15,096$422.5K0.00%+5,399+55.7%Added
Erste Asset Management GmbH14,000$391.7K0.00%00.0%Unchanged
Cubist Systematic Strategies, LLC12,371$346.3K0.00%+12,371New
Citadel Advisors LLC11,707$327.7K0.00%+11,707New
Aquatic Capital Management LLC10,709$299.7K0.01%−13,316−55.4%Reduced
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management9,312$260.6K0.01%+9,312New
Graham Capital Management, L.P.8,538$239.0K0.01%+8,538New
Commonwealth Equity Services, LLC8,382$235.0K0.00%−2,978−26.2%Reduced
Clear Street Markets LLC8,234$230.5K0.08%+8,234New
Headlands Technologies LLC7,973$223.2K0.03%+7,973New
Geode Capital Management, LLC7,851$219.7K0.00%+7,851New
Two Sigma Advisers, LP7,500$209.9K0.00%−36,000−82.8%Reduced
BNP Paribas Arbitrage, SA6,549$183.3K0.00%−879−11.8%Reduced
Rhumbline Advisers3,855$107.9K0.00%−33−0.8%Reduced
China Universal Asset Management Co., Ltd.2,976$83.3K0.01%+45+1.5%Added
Signaturefd, LLC1,565$43.8K0.00%−299−16.0%Reduced
Van Eck Associates Corp1,111$31.0K0.00%00.0%Unchanged
State of Wyoming1,018$28.5K0.00%+1,018New
Cacti Asset Management LLC1,000$28.0K0.00%00.0%Unchanged
GAMMA Investing LLC821$23.0K0.00%+417+103.2%Added
Citigroup Inc776$21.7K0.00%−28,922−97.4%Reduced
Mirae Asset Global Investments Co., Ltd.572$16.0K0.00%+83+17.0%Added
SRS Capital Advisors, Inc.433$12.1K0.00%+393+982.5%Added
Zurcher Kantonalbank (Zurich Cantonalbank)409$11.4K0.00%−46−10.1%Reduced
EverSource Wealth Advisors, LLC408$11.4K0.00%+408New
GF Fund Management Co. Ltd.357$9.99K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.347$9.68K0.00%+60+20.9%Added
Principal Securities, Inc.186$5.21K0.00%+58+45.3%Added
Allworth Financial LP135$3.78K0.00%+126+1,400.0%Added
Parallel Advisors, LLC103$2.88K0.00%−153−59.8%Reduced
US Bancorp94$2.63K0.00%−56−37.3%Reduced
Caitong International Asset Management Co., Ltd90$2.52K0.00%+18+25.0%Added
Bryn Mawr Trust Co74$2.07K0.00%00.0%Unchanged
Larson Financial Group LLC60$1.68K0.00%+60New
MAI Capital Management52$1.46K0.00%+52New
Daiwa Securities Group Inc.51$1.00K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.29$8120.00%−71−71.0%Reduced
TD Private Client Wealth LLC24$6720.00%+24New
Assetmark, Inc12$3360.00%+12New
Ronald Blue Trust, Inc.10$2800.00%00.0%Unchanged
GWM Advisors LLC6$1680.00%00.0%Unchanged
BVF Inc0$00.00%−1,454,422−100.0%Sold out
Deep Track Capital, LP0$00.00%−741,068−100.0%Sold out
Finepoint Capital LP0$00.00%−656,587−100.0%Sold out
Newtyn Management, LLC0$00.00%−200,000−100.0%Sold out
Vestal Point Capital, LP0$00.00%−200,000−100.0%Sold out
683 Capital Management, LLC0$00.00%−110,100−100.0%Sold out
Stonepine Capital Management, LLC0$00.00%−93,968−100.0%Sold out
J. Goldman & Co LP0$00.00%−84,307−100.0%Sold out
Old Mission Capital LLC0$00.00%−75,043−100.0%Sold out
Tejara Capital Ltd0$00.00%−53,786−100.0%Sold out
Abc Arbitrage SA0$00.00%−13,241−100.0%Sold out
Squarepoint Ops LLC0$00.00%−8,154−100.0%Sold out
Quadrant Capital Group LLC0$00.00%−4,429−100.0%Sold out
Group One Trading, L.P.0$00.00%−3,135−100.0%Sold out
Simplex Trading, LLC0$00.00%−1,724−100.0%Sold out