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Lakefront Biotherapeutics NV

LKFT
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001421876

No open-market purchases or sales by Lakefront Biotherapeutics NV insiders were filed in the last 90 days; 76 institutions reported holding it in 13F filings for Q2 2026, worth $960.3M in total; Greenlight Capital is the only superinvestor holding it.

Other share classesGLPGF

13F holders, Q1 2025

Institutional positions in Lakefront Biotherapeutics NV as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
83
+1 vs. Q4 2024
Shares held
31.2M
+111.2K (+0.4%) vs. Q4 2024
Total value
$783.2M
−$73.7M (−8.6%) vs. Q4 2024
New holders
17
22 more added
Sold out
16
30 more reduced

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LKFT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 83 institutions
Q1 2021: 133 institutionsQ2 2021: 109 institutionsQ3 2021: 81 institutionsQ4 2021: 83 institutionsQ1 2022: 90 institutionsQ2 2022: 82 institutionsQ3 2022: 84 institutionsQ4 2022: 75 institutionsQ1 2023: 76 institutionsQ2 2023: 76 institutionsQ3 2023: 73 institutionsQ4 2023: 88 institutionsQ1 2024: 83 institutionsQ2 2024: 85 institutionsQ3 2024: 79 institutionsQ4 2024: 82 institutionsQ1 2025: 83 institutionsQ2 2025: 85 institutionsQ3 2025: 92 institutionsQ4 2025: 91 institutionsQ1 2026: 90 institutionsQ2 2026: 76 institutions
Value heldQ1 2025: $783.2M
Q1 2021: $506.0MQ2 2021: $517.2MQ3 2021: $449.8MQ4 2021: $595.0MQ1 2022: $795.8MQ2 2022: $720.0MQ3 2022: $551.1MQ4 2022: $584.8MQ1 2023: $703.8MQ2 2023: $801.4MQ3 2023: $662.4MQ4 2023: $804.5MQ1 2024: $659.6MQ2 2024: $494.0MQ3 2024: $393.4MQ4 2024: $856.9MQ1 2025: $783.2MQ2 2025: $887.2MQ3 2025: $1.09BQ4 2025: $1.03BQ1 2026: $937.9MQ2 2026: $960.3M
Institutions holding LKFT and their total value by quarter
QuarterHoldersValue
Q2 202676$960.3M
Q1 202690$937.9M
Q4 202591$1.03B
Q3 202592$1.09B
Q2 202585$887.2M
Q1 202583$783.2M
Q4 202482$856.9M
Q3 202479$393.4M
Q2 202485$494.0M
Q1 202483$659.6M
Q4 202388$804.5M
Q3 202373$662.4M
Q2 202376$801.4M
Q1 202376$703.8M
Q4 202275$584.8M
Q3 202284$551.1M
Q2 202282$720.0M
Q1 202290$795.8M
Q4 202183$595.0M
Q3 202181$449.8M
Q2 2021109$517.2M
Q1 2021133$506.0M

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Lakefront Biotherapeutics NV; share changes are against Q4 2024.

Institutions holding LKFT in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Gilead Sciences, Inc.16,707,477$419.4M35.50%00.0%Unchanged
Tang Capital Management LLC3,961,797$99.5M5.51%+1,800,597+83.3%Added
FMR LLC1,556,856$39.1M0.00%−37,953−2.4%Reduced
BVF Inc1,454,422$36.5M1.49%−115,000−7.3%Reduced
Prosight Management, LP1,314,898$33.0M10.85%+289,898+28.3%Added
Deep Track Capital, LP741,068$18.6M0.60%−39,710−5.1%Reduced
Finepoint Capital LP656,587$16.5M2.78%−18,175−2.7%Reduced
Segall Bryant & Hamill, LLC651,461$16.4M0.25%−34,406−5.0%Reduced
Hudson Bay Capital Management LP565,000$14.2M0.09%+10,700+1.9%Added
DME Capital Management, LPSuperinvestorGreenlight Capital482,746$12.1M0.61%+3,383+0.7%Added
Renaissance Technologies LLC330,800$8.31M0.01%+34,700+11.7%Added
BlackRock, Inc.253,951$6.38M0.00%−170,713−40.2%Reduced
Newtyn Management, LLC200,000$5.02M0.79%−70,000−25.9%Reduced
Vestal Point Capital, LP200,000$5.02M0.36%+20,000+11.1%Added
EcoR1 Capital, LLC155,006$3.89M0.23%00.0%Unchanged
Primecap Management Co147,210$3.70M0.00%−484,000−76.7%Reduced
DAFNA Capital Management LLC130,175$3.27M0.93%00.0%Unchanged
Norges Bank120,000$3.01M0.00%00.0%Unchanged
Jane Street Group, LLC110,783$2.78M0.01%+99,646+894.7%Added
683 Capital Management, LLC110,100$2.77M0.28%+40,100+57.3%Added
UBS Group AG109,011$2.74M0.00%+33,432+44.2%Added
Stonepine Capital Management, LLC93,968$2.36M2.74%−106,032−53.0%Reduced
J. Goldman & Co LP84,307$2.12M0.08%+84,307New
Old Mission Capital LLC75,043$1.89M0.04%+75,043New
Ameriprise Financial Inc64,700$1.63M0.00%−5,713−8.1%Reduced
Millennium Management LLC63,064$1.58M0.00%+20,789+49.2%Added
D. E. Shaw & Co., Inc.63,020$1.58M0.00%+63,020New
Bank of America Corp59,606$1.50M0.00%+37,152+165.5%Added
Tejara Capital Ltd53,786$1.35M0.67%+53,786New
Crossmark Global Holdings, Inc.49,332$1.24M0.02%+169+0.3%Added
Two Sigma Investments, LP49,161$1.23M0.00%+49,161New
Alps Advisors Inc48,286$1.21M0.01%−5,169−9.7%Reduced
Two Sigma Advisers, LP43,500$1.09M0.00%+43,500New
Centiva Capital, LP38,551$968.4K0.06%+38,551New
Suvretta Capital Management, LLC37,111$932.2K0.04%00.0%Unchanged
Monaco Asset Management SAM36,036$905.2K0.46%+21,036+140.2%Added
Barclays PLC31,860$800.3K0.00%+31,029+3,733.9%Added
Optiver Holding B.V.30,408$763.8K0.03%+30,408New
Verition Fund Management LLC30,075$755.5K0.00%+12,386+70.0%Added
Citigroup Inc29,698$746.0K0.00%−157−0.5%Reduced
American Century Companies Inc27,839$699.3K0.00%+1,987+7.7%Added
Moody National Bank Trust Division26,140$656.6K0.07%00.0%Unchanged
Morgan Stanley25,407$638.2K0.00%−118,730−82.4%Reduced
Aquatic Capital Management LLC24,025$603.5K0.02%−2,393−9.1%Reduced
Susquehanna International Group, LLP22,912$575.5K0.00%+22,912New
Prelude Capital Management, LLC19,305$484.9K0.05%+170+0.9%Added
Erste Asset Management GmbH14,000$356.4K0.00%00.0%Unchanged
Barometer Capital Management Inc.13,517$339.5K0.13%+4,100+43.5%Added
Abc Arbitrage SA13,241$332.6K0.06%+13,241New
Commonwealth Equity Services, LLC11,360$285.0K0.00%+11,360New
QRG Capital Management, Inc.9,697$243.6K0.00%−758−7.3%Reduced
Squarepoint Ops LLC8,154$204.8K0.00%+8,154New
BNP Paribas Arbitrage, SA7,428$186.6K0.00%−1,544−17.2%Reduced
Quadrant Capital Group LLC4,429$111.3K0.00%−5,311−54.5%Reduced
Rhumbline Advisers3,888$97.7K0.00%−935−19.4%Reduced
Group One Trading, L.P.3,135$78.8K0.00%+3,135New
China Universal Asset Management Co., Ltd.2,931$73.6K0.01%−31−1.0%Reduced
Signaturefd, LLC1,864$46.8K0.00%−4,972−72.7%Reduced
Simplex Trading, LLC1,724$43.0K0.00%+1,724New
Tower Research Capital LLC (TRC)1,385$34.8K0.00%+555+66.9%Added
Van Eck Associates Corp1,111$28.0K0.00%−42−3.6%Reduced
Cacti Asset Management LLC1,000$25.5K0.00%00.0%Unchanged
Royal Bank of Canada882$23.0K0.00%−511−36.7%Reduced
JPMorgan Chase & Co835$21.0K0.00%−216−20.6%Reduced
Mirae Asset Global Investments Co., Ltd.489$12.4K0.00%+24+5.2%Added
Zurcher Kantonalbank (Zurich Cantonalbank)455$11.4K0.00%+455New
GAMMA Investing LLC404$10.1K0.00%−1,829−81.9%Reduced
GF Fund Management Co. Ltd.357$8.97K0.00%+64+21.8%Added
Advisor Group Holdings, Inc.287$7.21K0.00%−97−25.3%Reduced
Parallel Advisors, LLC256$6.43K0.00%−861−77.1%Reduced
US Bancorp150$3.77K0.00%−159−51.5%Reduced
Principal Securities, Inc.128$3.52K0.00%00.0%Unchanged
Hexagon Capital Partners LLC133$3.34K0.00%+60+82.2%Added
Lindbrook Capital, LLC131$3.29K0.00%−453−77.6%Reduced
The PNC Financial Services Group, Inc.100$2.51K0.00%−9−8.3%Reduced
Bryn Mawr Trust Co74$1.86K0.00%00.0%Unchanged
Skopos Labs, Inc.74$1.86K0.00%+74New
Caitong International Asset Management Co., Ltd72$1.81K0.00%+72New
SRS Capital Advisors, Inc.40$1.00K0.00%00.0%Unchanged
Daiwa Securities Group Inc.51$1.00K0.00%00.0%Unchanged
Ronald Blue Trust, Inc.10$2510.00%00.0%Unchanged
Allworth Financial LP9$2390.00%−12−57.1%Reduced
GWM Advisors LLC6$1510.00%00.0%Unchanged
Farther Finance Advisors, LLC0$00.00%−159−100.0%Sold out
Deerfield Management Company, L.P. (Series C)0$00.00%−1,411,000−100.0%Sold out
Citadel Advisors LLC0$00.00%−49,373−100.0%Sold out
Woodline Partners LP0$00.00%−45,899−100.0%Sold out
Goldman Sachs Group Inc0$00.00%−24,731−100.0%Sold out
Creative Planning0$00.00%−20,963−100.0%Sold out
XTX Topco Ltd0$00.00%−19,833−100.0%Sold out
Wealthedge Investment Advisors, LLC0$00.00%−11,301−100.0%Sold out
Driehaus Capital Management LLC0$00.00%−11,235−100.0%Sold out
LMR Partners LLP0$00.00%−10,768−100.0%Sold out
JustInvest LLC0$00.00%−9,257−100.0%Sold out
Geode Capital Management, LLC0$00.00%−7,819−100.0%Sold out
R Squared Ltd0$00.00%−930−100.0%Sold out
Rise Advisors, LLC0$00.00%−425−100.0%Sold out
UMA Financial Services, Inc.0$00.00%−139−100.0%Sold out
IFP Advisors, Inc0$00.00%0Sold out