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Lakefront Biotherapeutics NV

LKFT
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001421876

No open-market purchases or sales by Lakefront Biotherapeutics NV insiders were filed in the last 90 days; 76 institutions reported holding it in 13F filings for Q2 2026, worth $960.3M in total; Greenlight Capital is the only superinvestor holding it.

Other share classesGLPGF

13F holders, Q1 2026

Institutional positions in Lakefront Biotherapeutics NV as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
90
+2 vs. Q4 2025
Shares held
31.3M
+46.6K (+0.1%) vs. Q4 2025
Total value
$937.9M
−$86.9M (−8.5%) vs. Q4 2025
New holders
16
33 more added
Sold out
14
28 more reduced

3 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LKFT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 90 institutions
Q1 2021: 133 institutionsQ2 2021: 109 institutionsQ3 2021: 81 institutionsQ4 2021: 83 institutionsQ1 2022: 90 institutionsQ2 2022: 82 institutionsQ3 2022: 84 institutionsQ4 2022: 75 institutionsQ1 2023: 76 institutionsQ2 2023: 76 institutionsQ3 2023: 73 institutionsQ4 2023: 88 institutionsQ1 2024: 83 institutionsQ2 2024: 85 institutionsQ3 2024: 79 institutionsQ4 2024: 82 institutionsQ1 2025: 83 institutionsQ2 2025: 85 institutionsQ3 2025: 92 institutionsQ4 2025: 91 institutionsQ1 2026: 90 institutionsQ2 2026: 76 institutions
Value heldQ1 2026: $937.9M
Q1 2021: $506.0MQ2 2021: $517.2MQ3 2021: $449.8MQ4 2021: $595.0MQ1 2022: $795.8MQ2 2022: $720.0MQ3 2022: $551.1MQ4 2022: $584.8MQ1 2023: $703.8MQ2 2023: $801.4MQ3 2023: $662.4MQ4 2023: $804.5MQ1 2024: $659.6MQ2 2024: $494.0MQ3 2024: $393.4MQ4 2024: $856.9MQ1 2025: $783.2MQ2 2025: $887.2MQ3 2025: $1.09BQ4 2025: $1.03BQ1 2026: $937.9MQ2 2026: $960.3M
Institutions holding LKFT and their total value by quarter
QuarterHoldersValue
Q2 202676$960.3M
Q1 202690$937.9M
Q4 202591$1.03B
Q3 202592$1.09B
Q2 202585$887.2M
Q1 202583$783.2M
Q4 202482$856.9M
Q3 202479$393.4M
Q2 202485$494.0M
Q1 202483$659.6M
Q4 202388$804.5M
Q3 202373$662.4M
Q2 202376$801.4M
Q1 202376$703.8M
Q4 202275$584.8M
Q3 202284$551.1M
Q2 202282$720.0M
Q1 202290$795.8M
Q4 202183$595.0M
Q3 202181$449.8M
Q2 2021109$517.2M
Q1 2021133$506.0M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Lakefront Biotherapeutics NV; share changes are against Q4 2025.

Institutions holding LKFT in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Gilead Sciences, Inc.16,707,477$501.2M23.67%00.0%Unchanged
Tang Capital Management LLC3,785,991$113.6M5.77%−135,228−3.4%Reduced
Madison Avenue Partners, LP2,465,179$74.0M3.22%+252,010+11.4%Added
EcoR1 Capital, LLC1,667,119$50.0M2.14%00.0%Unchanged
Prosight Management, LP1,550,000$46.5M7.63%+475,888+44.3%Added
Ameriprise Financial Inc1,424,674$42.7M0.01%−26,565−1.8%Reduced
DME Capital Management, LPSuperinvestorGreenlight Capital482,746$14.5M0.45%00.0%Unchanged
Segall Bryant & Hamill, LLC426,412$12.8M0.18%−21,684−4.8%Reduced
Point72 Asset Management, L.P.332,125$9.96M0.02%−154,084−31.7%Reduced
Renaissance Technologies LLC315,400$9.46M0.01%+4,800+1.5%Added
BlackRock, Inc.312,106$9.36M0.00%−2,163−0.7%Reduced
D. E. Shaw & Co., Inc.215,718$6.47M0.01%−59,281−21.6%Reduced
UBS Group AG175,289$5.26M0.00%−174,155−49.8%Reduced
DAFNA Capital Management LLC130,175$3.91M0.89%00.0%Unchanged
Citadel Advisors LLC124,428$3.73M0.00%+35,032+39.2%Added
Millennium Management LLC107,912$3.24M0.00%−231,442−68.2%Reduced
Old Mission Capital LLC95,591$2.87M0.07%+95,591New
Man Group plc80,209$2.41M0.00%+32,628+68.6%Added
Hudson Bay Capital Management LP77,500$2.33M0.01%−92,500−54.4%Reduced
Tower Research Capital LLC (TRC)66,536$2.00M0.05%+65,988+12,041.6%Added
Alps Advisors Inc53,661$1.61M0.01%−130−0.2%Reduced
Acadian Asset Management LLC45,942$1.37M0.00%+38,401+509.2%Added
Goldman Sachs Group Inc45,371$1.36M0.00%+34,227+307.1%Added
HRT Financial LP45,168$1.35M0.00%+45,168New
American Century Companies Inc38,790$1.16M0.00%+12,061+45.1%Added
Barometer Capital Management Inc.38,100$1.14M0.39%+1,000+2.7%Added
Crossmark Global Holdings, Inc.32,607$978.2K0.01%−370−1.1%Reduced
Monaco Asset Management SAM27,520$825.6K0.26%−5,000−15.4%Reduced
Morgan Stanley26,619$798.6K0.00%−41,666−61.0%Reduced
Optiver Holding B.V.26,535$796.0K0.03%+26,535New
Two Sigma Investments, LP25,860$775.8K0.00%+9,500+58.1%Added
XTX Topco Ltd25,404$762.1K0.01%+2,185+9.4%Added
Moody National Bank Trust Division20,849$625.5K0.06%00.0%Unchanged
Bank of America Corp20,725$621.8K0.00%−10,244−33.1%Reduced
QRG Capital Management, Inc.19,705$591.1K0.01%+3,535+21.9%Added
Prelude Capital Management, LLC19,305$579.1K0.04%00.0%Unchanged
Jane Street Group, LLC13,607$408.2K0.00%+13,607New
Voloridge Investment Management, LLC13,505$405.1K0.00%−30,351−69.2%Reduced
Erste Asset Management GmbH14,000$403.8K0.00%00.0%Unchanged
Susquehanna International Group, LLP13,387$401.6K0.00%+6,419+92.1%Added
Squarepoint Ops LLC12,952$388.6K0.00%+12,952New
Abc Arbitrage SA12,744$382.3K0.05%+12,744New
Aquatic Capital Management LLC11,859$355.8K0.01%−1,853−13.5%Reduced
BNP Paribas Arbitrage, SA11,292$338.8K0.00%+194+1.7%Added
denkapparat Operations GmbH10,636$319.1K0.13%+10,636New
Commonwealth Equity Services, LLC10,499$315.0K0.00%+1,638+18.5%Added
Cerity Partners LLC10,310$309.3K0.00%+10,310New
Geode Capital Management, LLC10,150$304.5K0.00%+2,299+29.3%Added
Commonwealth of Pennsylvania Public School Empls Retrmt Sys8,273$248.2K0.00%+8,273New
Brinker Capital Investments, LLC7,426$222.8K0.00%+7,426New
Rhumbline Advisers7,381$221.4K0.00%+409+5.9%Added
Simplex Trading, LLC7,227$216.8K0.01%+7,153+9,666.2%Added
Axq Capital, LP6,777$203.3K0.03%+6,777New
Group One Trading, L.P.5,082$152.5K0.01%+5,082New
Quadrant Capital Group LLC3,653$109.6K0.00%+133+3.8%Added
China Universal Asset Management Co., Ltd.2,631$78.9K0.01%+275+11.7%Added
Van Eck Associates Corp2,153$65.0K0.00%+185+9.4%Added
GAMMA Investing LLC2,005$60.1K0.00%+755+60.4%Added
Signaturefd, LLC1,611$48.3K0.00%−30−1.8%Reduced
Wells Fargo & Company1,200$36.0K0.00%+1,200New
Cacti Asset Management LLC1,000$30.0K0.00%00.0%Unchanged
State of Wyoming991$29.7K0.00%−236−19.2%Reduced
SRS Capital Advisors, Inc.874$26.2K0.00%−1,461−62.6%Reduced
Royal Bank of Canada672$20.0K0.00%−4,683−87.5%Reduced
Citigroup Inc498$14.9K0.00%+94+23.3%Added
Advisor Group Holdings, Inc.483$14.5K0.00%+113+30.5%Added
EverSource Wealth Advisors, LLC441$13.2K0.00%+409+1,278.1%Added
Smartleaf Asset Management LLC360$10.4K0.00%−29−7.5%Reduced
GF Fund Management Co. Ltd.318$9.54K0.00%+36+12.8%Added
Larson Financial Group LLC286$8.58K0.00%−2−0.7%Reduced
Farther Finance Advisors, LLC274$8.15K0.00%+129+89.0%Added
Barclays PLC178$5.34K0.00%−2,177−92.4%Reduced
JPMorgan Chase & Co150$4.33K0.00%−89−37.2%Reduced
US Bancorp144$4.32K0.00%−38−20.9%Reduced
Allworth Financial LP137$4.11K0.00%−2−1.4%Reduced
Parallel Advisors, LLC103$3.09K0.00%00.0%Unchanged
Bessemer Group Inc102$3.00K0.00%+61+148.8%Added
MAI Capital Management70$2.10K0.00%+18+34.6%Added
TD Private Client Wealth LLC61$1.83K0.00%+37+154.2%Added
Bryn Mawr Trust Co36$1.08K0.00%00.0%Unchanged
Assetmark, Inc25$7500.00%+3+13.6%Added
Manning & Napier Advisors LLC25$7210.00%−1−3.8%Reduced
Signature Equity Partners, LLC23$6900.00%+1+4.5%Added
The PNC Financial Services Group, Inc.22$6600.00%00.0%Unchanged
IMA Wealth, Inc.15$4500.00%00.0%Unchanged
Retirement Wealth Solutions LLC12$3600.00%+12New
Tidemark, LLC10$3000.00%+10New
GWM Advisors LLC6$1800.00%00.0%Unchanged
CWM, LLC3$900.00%+3New
FMR LLC1$300.00%−56,968−100.0%Reduced
Massar Capital Management, LP0$00.00%−39,000−100.0%Sold out
Western Standard LLC0$00.00%−32,000−100.0%Sold out
Jump Financial, LLC0$00.00%−29,000−100.0%Sold out
Quadrature Capital Ltd0$00.00%−15,006−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−11,300−100.0%Sold out
Marshall Wace, LLP0$00.00%−11,200−100.0%Sold out
Ascent Group, LLC0$00.00%−6,237−100.0%Sold out
Mirae Asset Global Investments Co., Ltd.0$00.00%−702−100.0%Sold out
Zurcher Kantonalbank (Zurich Cantonalbank)0$00.00%−281−100.0%Sold out
SageView Advisory Group, LLC0$00.00%−80−100.0%Sold out