Lakefront Biotherapeutics NV
LKFT- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001421876
No open-market purchases or sales by Lakefront Biotherapeutics NV insiders were filed in the last 90 days; 76 institutions reported holding it in 13F filings for Q2 2026, worth $960.3M in total; Greenlight Capital is the only superinvestor holding it.
Other share classesGLPGF
13F holders, Q4 2025
Institutional positions in Lakefront Biotherapeutics NV as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 91
- 0 vs. Q3 2025
- Shares held
- 31.4M
- +99.4K (+0.3%) vs. Q3 2025
- Total value
- $1.03B
- −$53.5M (−4.9%) vs. Q3 2025
- New holders
- 16
- 28 more added
- Sold out
- 16
- 33 more reduced
1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LKFT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 76 | $960.3M |
| Q1 2026 | 90 | $937.9M |
| Q4 2025 | 91 | $1.03B |
| Q3 2025 | 92 | $1.09B |
| Q2 2025 | 85 | $887.2M |
| Q1 2025 | 83 | $783.2M |
| Q4 2024 | 82 | $856.9M |
| Q3 2024 | 79 | $393.4M |
| Q2 2024 | 85 | $494.0M |
| Q1 2024 | 83 | $659.6M |
| Q4 2023 | 88 | $804.5M |
| Q3 2023 | 73 | $662.4M |
| Q2 2023 | 76 | $801.4M |
| Q1 2023 | 76 | $703.8M |
| Q4 2022 | 75 | $584.8M |
| Q3 2022 | 84 | $551.1M |
| Q2 2022 | 82 | $720.0M |
| Q1 2022 | 90 | $795.8M |
| Q4 2021 | 83 | $595.0M |
| Q3 2021 | 81 | $449.8M |
| Q2 2021 | 109 | $517.2M |
| Q1 2021 | 133 | $506.0M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Lakefront Biotherapeutics NV; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Gilead Sciences, Inc. | 16,707,477 | $550.6M | 28.45% | 00.0% | Unchanged |
| Tang Capital Management LLC | 3,921,219 | $128.2M | 6.33% | −229,975−5.5% | Reduced |
| Madison Avenue Partners, LP | 2,213,169 | $72.4M | 3.11% | +17,394+0.8% | Added |
| EcoR1 Capital, LLC | 1,667,119 | $54.5M | 2.50% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 1,451,239 | $47.5M | 0.01% | +34,305+2.4% | Added |
| Prosight Management, LP | 1,074,112 | $35.1M | 7.26% | −75,888−6.6% | Reduced |
| Point72 Asset Management, L.P. | 486,209 | $15.9M | 0.02% | +42,340+9.5% | Added |
| DME Capital Management, LPSuperinvestorGreenlight Capital | 482,746 | $15.8M | 0.55% | 00.0% | Unchanged |
| Segall Bryant & Hamill, LLC | 448,096 | $14.7M | 0.20% | −39,100−8.0% | Reduced |
| UBS Group AG | 349,444 | $11.4M | 0.00% | +196,445+128.4% | Added |
| Millennium Management LLC | 339,354 | $11.1M | 0.01% | +186,452+121.9% | Added |
| BlackRock, Inc. | 314,269 | $10.3M | 0.00% | +74,426+31.0% | Added |
| Renaissance Technologies LLC | 310,600 | $10.2M | 0.02% | −45,600−12.8% | Reduced |
| D. E. Shaw & Co., Inc. | 274,999 | $8.99M | 0.01% | +73,830+36.7% | Added |
| Hudson Bay Capital Management LP | 170,000 | $5.56M | 0.03% | −75,000−30.6% | Reduced |
| DAFNA Capital Management LLC | 130,175 | $4.26M | 0.99% | 00.0% | Unchanged |
| Norges Bank | 90,000 | $2.94M | 0.00% | +90,000 | New |
| Kotler Kevin | 90,000 | $2.94M | 2.17% | +90,000 | New |
| Citadel Advisors LLC | 89,396 | $2.92M | 0.00% | +73,427+459.8% | Added |
| Morgan Stanley | 68,285 | $2.23M | 0.00% | +4,222+6.6% | Added |
| FMR LLC | 56,969 | $1.86M | 0.00% | +2,958+5.5% | Added |
| Alps Advisors Inc | 53,791 | $1.76M | 0.01% | +21,886+68.6% | Added |
| Man Group plc | 47,581 | $1.56M | 0.00% | +11,384+31.5% | Added |
| Voloridge Investment Management, LLC | 43,856 | $1.43M | 0.01% | −43,716−49.9% | Reduced |
| Massar Capital Management, LP | 39,000 | $1.28M | 0.25% | +39,000 | New |
| Crossmark Global Holdings, Inc. | 32,977 | $1.08M | 0.02% | +80+0.2% | Added |
| Monaco Asset Management SAM | 32,520 | $1.06M | 0.32% | −1,016−3.0% | Reduced |
| Western Standard LLC | 32,000 | $1.05M | 0.48% | +32,000 | New |
| Bank of America Corp | 30,969 | $1.01M | 0.00% | +20+0.1% | Added |
| Jump Financial, LLC | 29,000 | $948.3K | 0.01% | −22,300−43.5% | Reduced |
| Barometer Capital Management Inc. | 37,100 | $883.7K | 0.29% | +9,483+34.3% | Added |
| American Century Companies Inc | 26,729 | $874.0K | 0.00% | −874−3.2% | Reduced |
| XTX Topco Ltd | 23,219 | $759.3K | 0.02% | +11,162+92.6% | Added |
| Moody National Bank Trust Division | 20,849 | $681.8K | 0.07% | 00.0% | Unchanged |
| Prelude Capital Management, LLC | 19,305 | $631.3K | 0.05% | −22−0.1% | Reduced |
| Two Sigma Investments, LP | 16,360 | $535.0K | 0.00% | −6,099−27.2% | Reduced |
| QRG Capital Management, Inc. | 16,170 | $528.8K | 0.01% | +1,077+7.1% | Added |
| Quadrature Capital Ltd | 15,006 | $490.7K | 0.01% | −11,239−42.8% | Reduced |
| Erste Asset Management GmbH | 14,000 | $463.7K | 0.00% | 00.0% | Unchanged |
| Aquatic Capital Management LLC | 13,712 | $448.4K | 0.01% | −3,804−21.7% | Reduced |
| Two Sigma Advisers, LP | 11,300 | $369.5K | 0.00% | +2,600+29.9% | Added |
| Marshall Wace, LLP | 11,200 | $366.2K | 0.00% | −27,260−70.9% | Reduced |
| Goldman Sachs Group Inc | 11,144 | $364.4K | 0.00% | −54,997−83.2% | Reduced |
| BNP Paribas Arbitrage, SA | 11,098 | $362.9K | 0.00% | −756−6.4% | Reduced |
| Commonwealth Equity Services, LLC | 8,861 | $289.8K | 0.00% | +13+0.1% | Added |
| Geode Capital Management, LLC | 7,851 | $256.7K | 0.00% | 00.0% | Unchanged |
| Acadian Asset Management LLC | 7,541 | $246.0K | 0.00% | +7,541 | New |
| Rhumbline Advisers | 6,972 | $228.0K | 0.00% | +3,372+93.7% | Added |
| Susquehanna International Group, LLP | 6,968 | $227.9K | 0.00% | +6,968 | New |
| Ascent Group, LLC | 6,237 | $203.9K | 0.01% | −76−1.2% | Reduced |
| Royal Bank of Canada | 5,355 | $175.0K | 0.00% | −23,074−81.2% | Reduced |
| Quadrant Capital Group LLC | 3,520 | $115.1K | 0.00% | −360−9.3% | Reduced |
| China Universal Asset Management Co., Ltd. | 2,356 | $77.0K | 0.01% | −155−6.2% | Reduced |
| Barclays PLC | 2,355 | $77.0K | 0.00% | −36,647−94.0% | Reduced |
| SRS Capital Advisors, Inc. | 2,335 | $76.4K | 0.00% | +1,778+319.2% | Added |
| Van Eck Associates Corp | 1,968 | $64.0K | 0.00% | +750+61.6% | Added |
| Signaturefd, LLC | 1,641 | $53.7K | 0.00% | −199−10.8% | Reduced |
| GAMMA Investing LLC | 1,250 | $40.9K | 0.00% | −223−15.1% | Reduced |
| State of Wyoming | 1,227 | $40.1K | 0.00% | +271+28.3% | Added |
| Cacti Asset Management LLC | 1,000 | $33.1K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 702 | $23.0K | 0.00% | +148+26.7% | Added |
| Tower Research Capital LLC (TRC) | 548 | $17.9K | 0.00% | −49−8.2% | Reduced |
| Citigroup Inc | 404 | $13.2K | 0.00% | −13,449−97.1% | Reduced |
| Smartleaf Asset Management LLC | 389 | $12.7K | 0.00% | +389 | New |
| Advisor Group Holdings, Inc. | 370 | $12.1K | 0.00% | −255−40.8% | Reduced |
| DV Equities, LLC | 332 | $10.9K | 0.00% | +332 | New |
| Larson Financial Group LLC | 288 | $9.42K | 0.00% | +132+84.6% | Added |
| GF Fund Management Co. Ltd. | 282 | $9.22K | 0.00% | −23−7.5% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 281 | $9.19K | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 239 | $7.82K | 0.00% | +168+236.6% | Added |
| US Bancorp | 182 | $5.95K | 0.00% | +88+93.6% | Added |
| Farther Finance Advisors, LLC | 145 | $4.74K | 0.00% | +144+14,400.0% | Added |
| Allworth Financial LP | 139 | $4.55K | 0.00% | −44−24.0% | Reduced |
| Parallel Advisors, LLC | 103 | $3.37K | 0.00% | −50−32.7% | Reduced |
| SageView Advisory Group, LLC | 80 | $2.62K | 0.00% | +80 | New |
| Simplex Trading, LLC | 74 | $2.42K | 0.00% | −180−70.9% | Reduced |
| Daiwa Securities Group Inc. | 51 | $2.00K | 0.00% | 00.0% | Unchanged |
| MAI Capital Management | 52 | $1.70K | 0.00% | 00.0% | Unchanged |
| Crewe Advisors LLC | 46 | $1.50K | 0.00% | 00.0% | Unchanged |
| Bryn Mawr Trust Co | 36 | $1.18K | 0.00% | +36 | New |
| EverSource Wealth Advisors, LLC | 32 | $1.05K | 0.00% | −277−89.6% | Reduced |
| Bessemer Group Inc | 41 | $1.00K | 0.00% | +41 | New |
| Manning & Napier Advisors LLC | 26 | $848 | 0.00% | +26 | New |
| TD Private Client Wealth LLC | 24 | $785 | 0.00% | 00.0% | Unchanged |
| Assetmark, Inc | 22 | $719 | 0.00% | −20−47.6% | Reduced |
| The PNC Financial Services Group, Inc. | 22 | $719 | 0.00% | −4−15.4% | Reduced |
| Signature Equity Partners, LLC | 22 | $719 | 0.00% | +22 | New |
| IMA Wealth, Inc. | 15 | $490 | 0.00% | +15 | New |
| GWM Advisors LLC | 6 | $196 | 0.00% | 00.0% | Unchanged |
| Huntington National Bank | 4 | $131 | 0.00% | +4 | New |
| Caitong International Asset Management Co., Ltd | 4 | $131 | 0.00% | +4 | New |
| Primecap Management Co | 0 | $0 | 0.00% | −50,500−100.0% | Sold out |
| Matauro, LLC | 0 | $0 | 0.00% | −47,536−100.0% | Sold out |
| Suvretta Capital Management, LLC | 0 | $0 | 0.00% | −37,111−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −20,270−100.0% | Sold out |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | 0 | $0 | 0.00% | −17,469−100.0% | Sold out |
| National Bank of Canada | 0 | $0 | 0.00% | −14,281−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −9,049−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −8,697−100.0% | Sold out |
| Brinker Capital Investments, LLC | 0 | $0 | 0.00% | −7,261−100.0% | Sold out |