Caris Life Sciences, Inc.
CAI- Exchange
- Nasdaq
- Industry
- Services-Medical Laboratories
- SEC CIK
- 0002019410
In the last 90 days, Caris Life Sciences, Inc. insiders filed 1 open-market purchase and 3 sales; 247 institutions reported holding it in 13F filings for Q2 2026, worth $2.75B in total; superinvestors Coatue Management and Duquesne Family Office hold it.
13F holders, Q3 2025
Institutional positions in Caris Life Sciences, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 138
- +23 vs. Q2 2025
- Shares held
- 113.4M
- +4.45M (+4.1%) vs. Q2 2025
- Total value
- $3.41B
- +$495.5M (+17.0%) vs. Q2 2025
- New holders
- 53
- 45 more added
- Sold out
- 30
- 19 more reduced
1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CAI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 247 | $2.75B |
| Q1 2026 | 202 | $2.80B |
| Q4 2025 | 186 | $3.92B |
| Q3 2025 | 138 | $3.41B |
| Q2 2025 | 116 | $2.92B |
| Q1 2025 | 0 | $0 |
| Q4 2024 | 0 | $0 |
| Q3 2024 | 0 | $0 |
| Q2 2024 | 0 | $0 |
| Q1 2024 | 0 | $0 |
| Q4 2023 | 0 | $0 |
| Q3 2023 | 0 | $0 |
| Q2 2023 | 0 | $0 |
| Q1 2023 | 0 | $0 |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Caris Life Sciences, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sixth Street Partners Management Company, L.P. | 24,385,399 | $737.7M | 63.36% | 00.0% | Unchanged |
| Coatue Management LLCSuperinvestorCoatue Management | 10,142,198 | $306.8M | 0.75% | 00.0% | Unchanged |
| FMR LLC | 9,633,435 | $291.4M | 0.02% | +1,001,890+11.6% | Added |
| T. Rowe Price Investment Management, Inc. | 8,025,759 | $242.8M | 0.15% | +721,772+9.9% | Added |
| Braidwell LP | 7,316,142 | $221.3M | 6.57% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 6,924,745 | $209.5M | 0.02% | +163,941+2.4% | Added |
| Silver Lake Group, L.L.C. | 5,291,006 | $160.1M | 3.12% | 00.0% | Unchanged |
| Millennium Management LLC | 3,938,072 | $119.1M | 0.09% | +424,896+12.1% | Added |
| PointState Capital LP | 3,883,721 | $117.5M | 2.11% | +1,385,364+55.5% | Added |
| Neuberger Berman Group LLC | 4,345,042 | $109.1M | 0.08% | −1,894,478−30.4% | Reduced |
| OrbiMed Advisors LLC | 3,034,858 | $91.8M | 2.20% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 1,679,468 | $50.8M | 0.01% | +53,754+3.3% | Added |
| Morgan Stanley | 1,534,423 | $46.4M | 0.00% | +729,183+90.6% | Added |
| Clearbridge Investments, LLC | 1,381,230 | $41.8M | 0.03% | +124,105+9.9% | Added |
| Canada Pension Plan Investment Board | 1,322,752 | $40.0M | 0.03% | 00.0% | Unchanged |
| Longaeva Partners L.P. | 1,285,968 | $38.9M | 8.27% | −173,777−11.9% | Reduced |
| Alliancebernstein L.P. | 1,201,985 | $36.4M | 0.01% | +264,434+28.2% | Added |
| UBS Asset Management Americas Inc | 1,116,191 | $33.8M | 0.01% | +316,078+39.5% | Added |
| Alyeska Investment Group, L.P. | 1,101,071 | $33.3M | 0.10% | +725,071+192.8% | Added |
| Perceptive Advisors LLC | 1,098,163 | $33.2M | 0.96% | 00.0% | Unchanged |
| Ghisallo Capital Management LLC | 1,048,163 | $31.7M | 1.04% | 00.0% | Unchanged |
| Massachusetts Financial Services Co | 971,330 | $29.4M | 0.01% | −78,398−7.5% | Reduced |
| JPMorgan Chase & Co | 858,105 | $26.0M | 0.00% | −76,528−8.2% | Reduced |
| Lord, Abbett & Co. LLC | 850,000 | $25.7M | 0.08% | +850,000 | New |
| Invesco Ltd. | 803,802 | $24.3M | 0.00% | +297,065+58.6% | Added |
| Rock Springs Capital Management LP | 793,651 | $24.0M | 1.40% | 00.0% | Unchanged |
| Woodline Partners LP | 723,163 | $21.9M | 0.10% | −523,163−42.0% | Reduced |
| Janus Henderson Group PLC | 664,438 | $20.1M | 0.01% | −225,208−25.3% | Reduced |
| Point72 (DIFC) Ltd | 654,792 | $19.8M | 1.38% | +600,650+1,109.4% | Added |
| BlackRock, Inc. | 647,081 | $19.6M | 0.00% | +337,979+109.3% | Added |
| Bank of America Corp | 429,478 | $13.0M | 0.00% | +394,289+1,120.5% | Added |
| Geode Capital Management, LLC | 398,328 | $12.0M | 0.00% | +163,094+69.3% | Added |
| First Light Asset Management, LLC | 403,924 | $11.9M | 1.12% | −39,119−8.8% | Reduced |
| Walleye Capital LLC | 320,669 | $9.70M | 0.08% | +282,741+745.5% | Added |
| Goldman Sachs Group Inc | 282,209 | $8.54M | 0.00% | +99,956+54.8% | Added |
| Lazard Asset Management LLC | 277,537 | $8.40M | 0.01% | +107,608+63.3% | Added |
| Tudor Investment Corp Et Al | 264,551 | $8.00M | 0.05% | 00.0% | Unchanged |
| Freestone Grove Partners LP | 251,389 | $7.60M | 0.06% | +201,389+402.8% | Added |
| Point72 Asset Management, L.P. | 246,624 | $7.46M | 0.02% | −211,852−46.2% | Reduced |
| ARK Investment Management LLCSuperinvestorARK Invest | 245,350 | $7.42M | 0.04% | +198,300+421.5% | Added |
| UBS Group AG | 235,873 | $7.14M | 0.00% | +235,873 | New |
| FIL Ltd | 225,920 | $6.83M | 0.01% | −70,051−23.7% | Reduced |
| Renaissance Technologies LLC | 225,100 | $6.81M | 0.01% | +225,100 | New |
| TD Asset Management Inc | 222,336 | $6.73M | 0.01% | +22,512+11.3% | Added |
| Franklin Resources Inc | 216,964 | $6.56M | 0.00% | −310,075−58.8% | Reduced |
| Vanguard Group Inc | 175,544 | $5.31M | 0.00% | +25,544+17.0% | Added |
| Holocene Advisors, LP | 171,127 | $5.18M | 0.01% | −1,816−1.1% | Reduced |
| State Street Corp | 155,340 | $4.70M | 0.00% | +155,340 | New |
| State of Wisconsin Investment Board | 150,000 | $4.54M | 0.01% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 110,084 | $3.33M | 0.00% | +87,525+388.0% | Added |
| Seven Grand Managers, LLC | 100,000 | $3.02M | 0.25% | +50,000+100.0% | Added |
| Raymond James Financial Inc | 94,888 | $2.87M | 0.00% | +92,043+3,235.3% | Added |
| Pura Vida Investments, LLC | 89,940 | $2.72M | 17.65% | +44,940+99.9% | Added |
| Jennison Associates LLC | 84,459 | $2.55M | 0.00% | −202,165−70.5% | Reduced |
| Marshall Wace, LLP | 82,975 | $2.51M | 0.00% | +45,102+119.1% | Added |
| Burkehill Global Management, LP | 75,000 | $2.27M | 0.13% | 00.0% | Unchanged |
| Quantinno Capital Management LP | 72,223 | $2.18M | 0.01% | +72,223 | New |
| Cubist Systematic Strategies, LLC | 70,731 | $2.14M | 0.03% | +68,731+3,436.5% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 59,552 | $1.80M | 0.00% | +47,371+388.9% | Added |
| Soros Fund Management LLCSuperinvestorSoros Fund Management | 55,650 | $1.68M | 0.03% | +5,650+11.3% | Added |
| SRS Investment Management, LLC | 50,000 | $1.51M | 0.02% | 00.0% | Unchanged |
| D. E. Shaw & Co., Inc. | 49,785 | $1.51M | 0.00% | +42,285+563.8% | Added |
| Citigroup Inc | 48,445 | $1.47M | 0.00% | +48,433+403,608.3% | Added |
| Nikko Asset Management Americas, Inc. | 47,371 | $1.43M | 0.01% | +47,371 | New |
| Northern Trust Corp | 45,595 | $1.38M | 0.00% | +45,595 | New |
| Gotham Asset Management, LLC | 33,203 | $1.00M | 0.00% | +33,203 | New |
| Qube Research & Technologies Ltd | 32,752 | $990.7K | 0.00% | +24,998+322.4% | Added |
| Dark Forest Capital Management LP | 31,657 | $957.6K | 0.04% | +31,657 | New |
| Verition Fund Management LLC | 30,910 | $935.0K | 0.01% | +30,910 | New |
| Susquehanna International Group, LLP | 28,988 | $876.9K | 0.00% | +28,988 | New |
| Renaissance Capital LLC | 28,460 | $860.9K | 0.48% | +28,460 | New |
| XTX Topco Ltd | 28,081 | $849.5K | 0.04% | +28,081 | New |
| Deutsche Bank AG | 25,290 | $765.0K | 0.00% | 00.0% | Unchanged |
| Atika Capital Management LLC | 25,000 | $756.3K | 0.06% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 24,869 | $752.3K | 0.00% | +24,869 | New |
| WPWealth LLP | 23,036 | $696.8K | 0.11% | +23,036 | New |
| Nuveen, LLC | 22,413 | $678.0K | 0.00% | +22,413 | New |
| Engineers Gate Manager LP | 22,028 | $666.3K | 0.01% | +22,028 | New |
| Rhumbline Advisers | 21,497 | $650.3K | 0.00% | +21,497 | New |
| Park Avenue Securities LLC | 20,730 | $627.0K | 0.00% | +20,730 | New |
| MSA Advisors, LLC | 19,200 | $580.8K | 0.15% | 00.0% | Unchanged |
| Ieq Capital, LLC | 17,141 | $518.5K | 0.00% | +17,141 | New |
| Man Group plc | 16,078 | $486.4K | 0.00% | +16,078 | New |
| LPL Financial LLC | 15,991 | $483.7K | 0.00% | +6,799+74.0% | Added |
| Harbor Investment Advisory, LLC | 15,650 | $473.4K | 0.04% | +15,650 | New |
| Jane Street Group, LLC | 14,595 | $441.5K | 0.00% | +14,595 | New |
| US Bancorp | 12,722 | $384.8K | 0.00% | +854+7.2% | Added |
| Americana Partners, LLC | 12,433 | $376.1K | 0.01% | +12,433 | New |
| Triton Wealth Management, PLLC | 10,505 | $327.2K | 0.12% | 00.0% | Unchanged |
| Perbak Capital Partners LLP | 10,703 | $323.8K | 0.06% | +10,703 | New |
| CastleKnight Management LP | 10,436 | $315.7K | 0.02% | −102,994−90.8% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 10,372 | $313.8K | 0.00% | +10,372 | New |
| Worldquant Millennium Advisors LLC | 10,092 | $305.3K | 0.00% | +10,092 | New |
| Treasurer of the State of North Carolina | 10,073 | $305.0K | 0.00% | +10,073 | New |
| Bellevue Group AG | 9,605 | $290.6K | 0.01% | −395−4.0% | Reduced |
| Sandia Investment Management LP | 8,600 | $260.1K | 0.78% | −1,400−14.0% | Reduced |
| Davy Global Fund Management Ltd | 8,326 | $251.9K | 0.02% | +8,326 | New |
| Omers Administration Corp | 8,200 | $248.1K | 0.00% | +8,200 | New |
| Edmond de Rothschild Holding S.A. | 7,500 | $226.9K | 0.00% | +7,500 | New |
| Public Employees Retirement System of Ohio | 6,997 | $211.7K | 0.00% | +6,997 | New |