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Caris Life Sciences, Inc.

CAI
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0002019410

In the last 90 days, Caris Life Sciences, Inc. insiders filed 0 open-market purchases and 3 sales; 248 institutions reported holding it in 13F filings for Q2 2026, worth $2.75B in total; superinvestors Coatue Management and Duquesne Family Office hold it.

Key figures

Market capClose on Nov 11, 2026
$7.02B
Insider buysOpen market, last 90 days
0
Insider sellsLast 90 days, $27.2M in total
3
13F holdersQ2 2026, +45 vs. previous quarter
248
13F valueReported value at the end of Q2 2026
$2.75B
Superinvestors holdingAt the end of Q2 2026
2

Price chart

From SEC filings, in USD.

Revenue, FY2025
$812.0M
No comparable prior period
Net income, FY2025
-$68.1M
No comparable prior period
Free cash flow, FY2025
$66.9M
No comparable prior period
Revenue, Q3 FY2026
$275.4M
+27.0% year over year

Revenue flow, FY2025

Green is profit; orange is costs, expenses and taxes. Percentages are shares of revenue.

Net loss for FY2025: $68.1M (8.4% of revenue).

Short interest

See short data

From FINRA, settlement date Oct 30, 2026.

Short interest
11.5M
Shares sold short
Change
−2.09M
−15.4% vs. previous
Days to cover
3.98
At average daily volume

Superinvestors holding CAI, Q2 2026

Go to the superinvestors tab

2 superinvestors report holding Caris Life Sciences, Inc. on Form 13F. Percentages are the stock's share of each portfolio.

Coatue Management

Philippe Laffont

0.4%

Caris Life Sciences, Inc.'s share of the portfolio

Shares
9,819,992
Value
$175.0M

Duquesne Family Office

Stanley Druckenmiller

0.8%

Caris Life Sciences, Inc.'s share of the portfolio

Shares
1,894,450
Value
$33.8M

Latest insider trades

See all insider trades

Open-market purchases and sales by Caris Life Sciences, Inc. insiders from Form 4, newest first.

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Sep 23, 2026 (view filing)5:06 PM ETSep 221 dayDenton John RusselSee RemarksSSale−7.50K$31.82−$238.6K−4.1%174.9K after
Sep 17, 2026 (view filing)6:08 PM ETSep 17Same dayBrille Brian JSee RemarksSSale−400.0K$30.33−$12.1M−63.5%230.3K after
Sep 4, 2026 (view filing)4:59 PM ETSep 3-41 daySpetzler David BaxleyPresidentSSale−597.2K$24.84−$14.8M−33.5%1.18M after3 lots
Jul 13, 2026 (view filing)7:06 AM ETMay 1559 daysLateHalbert JonDirectorPPurchase+68.0K$14.56+$990.1K+10.7%704.6K after
May 12, 2026 (view filing)May 111 dayVacirca Jeff LDirectorPPurchase+31.1K$16.15+$501.5K+166.7%49.7K after
Dec 12, 2025 (view filing)Dec 111 dayPower Luke ThomasSee RemarksSSale−62.3K$26.57−$1.65M−38.5%99.6K after2 lots10b5-1
Nov 10, 2025 (view filing)Nov 73 daysSpetzler David BaxleyPresidentPPurchase+400$23.85+$9.54K+0.1%460.8K after
Nov 10, 2025 (view filing)Nov 73 daysDenton John RusselSee RemarksPPurchase+4.18K$24.09+$100.8K+83.7%9.18K after
Jun 23, 2025 (view filing)Jun 203 daysDenton John RusselSee RemarksPPurchase+7.50K$21.00+$157.5K+6.5%123.6K after
Jun 23, 2025 (view filing)Jun 203 daysBrille Brian JSee RemarksPPurchase+30.0K$21.00+$630.0K+22.7%162.4K after

Top 10 13F holders, Q2 2026

See all 248 holders

The largest institutional positions in Caris Life Sciences, Inc. at the end of Q2 2026; share changes are against Q1 2026.

Institutions holding CAI in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC30,923,878$551.1M0.02%+138,293+0.4%Added
J. H. Whitney Equity Partners VI, LLC11,256,615$200.6M100.00%−7,000,000−38.3%Reduced
Coatue Management LLCSuperinvestorCoatue Management9,819,992$175.0M0.36%00.0%Unchanged
Braidwell LP8,256,032$147.1M5.44%+246,585+3.1%Added
Sixth Street Partners Management Company, L.P.7,327,041$130.6M22.54%−7,058,358−49.1%Reduced
PointState Capital LP6,828,835$121.7M2.14%−531,611−7.2%Reduced
JPMorgan Chase & Co6,558,514$120.2M0.01%+3,098,299+89.5%Added
BlackRock, Inc.5,536,798$98.7M0.00%+679,686+14.0%Added
T. Rowe Price Investment Management, Inc.5,079,141$90.5M0.06%−509,116−9.1%Reduced
Vanguard Portfolio Management LLC4,844,431$86.3M0.00%+1,085,969+28.9%Added

Holders of 5% or more of CAI

See all 3 holders and filings

Holders whose latest Schedule 13D or 13G filing reports 5% or more of Caris Life Sciences, Inc..

Largest holders of CAI from 13D and 13G filings
HolderLatest formStakeChangeFirst filedLatest filingFiling
Halbert David D13G44.10%124.9M sharesNewAug 13, 20251 filingAug 13, 2025SEC
FMR LLC13G/A13.40%37.8M shares+2.60 ppfrom 10.80%Feb 5, 20263 filingsNov 5, 2026SEC
TSSP Sub-Fund HoldCo LLC13G8.80%24.4M sharesNewJul 28, 20251 filingJul 28, 2025SEC