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Caris Life Sciences, Inc.

CAI
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0002019410

In the last 90 days, Caris Life Sciences, Inc. insiders filed 1 open-market purchase and 3 sales; 247 institutions reported holding it in 13F filings for Q2 2026, worth $2.75B in total; superinvestors Coatue Management and Duquesne Family Office hold it.

Open-market trades, last 90 days

Open-market purchases (P) and sales (S) by Caris Life Sciences, Inc. insiders, counted by Form 4 filing. Trades with a flagged price and duplicate filings are left out.

Open-market buys
1 filing
1 insider, $990.1K in total
Open-market sells
3 filings
3 insiders, $27.2M in total
Insiders trading
4
Net value
−$26.2M
Purchases minus sales

Insider roster

Directors, officers and 10% owners who have filed a Form 4 for Caris Life Sciences, Inc., current and former, most recent filer first. Last reported holding is the position after the last non-derivative trade in their latest filing.

Insider roster for Caris Life Sciences, Inc.
NameTitleLast reported holdingLast filingFilings, past year
Denton John RusselSee Remarks174,855Sep 23, 20264
Brille Brian JSee Remarks230,303Sep 17, 20264
Spetzler David BaxleyPresident1,182,871Sep 4, 20264
Castleman Peter MDirector29,321Aug 14, 20263
Phillips T DannyDirector133,060Aug 14, 20262
Minor LloydDirector31,813Aug 14, 20262
Gilliam Joseph EDirector29,321Aug 14, 20261
Fredrickson David PaulDirector31,813Aug 14, 20262
Vacirca Jeff LDirector62,863Aug 14, 20263
Johansen Laura IDirector343,897Aug 14, 20261
Halbert JonDirector131,813Aug 14, 20263
Poste GeorgeDirector17,729Jun 2, 20261
Knowles Jonathan Kenneth CharlesDirector308,979Jun 2, 20261
Halbert David DSee Remarks2,574,533May 18, 20262
Power Luke ThomasSee Remarks153,771May 18, 20263
Vigano Paul R10% Owner20,256,615IndirectJun 23, 20250
Williams Robert M Jr10% Owner20,256,615IndirectJun 23, 20250
J H Whitney VI L P10% Owner20,256,615IndirectJun 23, 20250
J. H. Whitney Equity Partners VI, LLC10% Owner20,256,615IndirectJun 23, 20250
Caris Halbert, L.P.Director, 10% Owner121,025,002IndirectJun 23, 20250
ADAPT I Ltd.10% Owner16,943,232IndirectJun 23, 20250
Carisome I, L.P.10% Owner16,943,232IndirectJun 23, 20250
Waxman AlanOther: Former 10% Owner1,219,271IndirectJun 23, 20250
TSSP Sub-Fund HoldCo LLCOther: Former 10% Owner1,219,271IndirectJun 23, 20250

Insider trades

Each row adds up one type of transaction in one Form 4 filing. Only open-market purchases (P) and sales (S) are shown by default; use the filters to see grants, option exercises and other codes.

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Sep 23, 2026 (view filing)5:06 PM ETSep 221 dayDenton John RusselSee RemarksSSale−7.50K$31.82−$238.6K−4.1%174.9K after
Sep 17, 2026 (view filing)6:08 PM ETSep 17Same dayBrille Brian JSee RemarksSSale−400.0K$30.33−$12.1M−63.5%230.3K after
Sep 4, 2026 (view filing)4:59 PM ETSep 3-41 daySpetzler David BaxleyPresidentSSale−597.2K$24.84−$14.8M−33.5%1.18M after3 lots
Jul 13, 2026 (view filing)7:06 AM ETMay 1559 daysLateHalbert JonDirectorPPurchase+68.0K$14.56+$990.1K+10.7%704.6K after
May 12, 2026 (view filing)May 111 dayVacirca Jeff LDirectorPPurchase+31.1K$16.15+$501.5K+166.7%49.7K after
Dec 12, 2025 (view filing)Dec 111 dayPower Luke ThomasSee RemarksSSale−62.3K$26.57−$1.65M−38.5%99.6K after2 lots10b5-1
Nov 10, 2025 (view filing)Nov 73 daysSpetzler David BaxleyPresidentPPurchase+400$23.85+$9.54K+0.1%460.8K after
Nov 10, 2025 (view filing)Nov 73 daysDenton John RusselSee RemarksPPurchase+4.18K$24.09+$100.8K+83.7%9.18K after
Jun 23, 2025 (view filing)Jun 203 daysDenton John RusselSee RemarksPPurchase+7.50K$21.00+$157.5K+6.5%123.6K after
Jun 23, 2025 (view filing)Jun 203 daysBrille Brian JSee RemarksPPurchase+30.0K$21.00+$630.0K+22.7%162.4K after