Caris Life Sciences, Inc.
CAI- Exchange
- Nasdaq
- Industry
- Services-Medical Laboratories
- SEC CIK
- 0002019410
In the last 90 days, Caris Life Sciences, Inc. insiders filed 1 open-market purchase and 3 sales; 247 institutions reported holding it in 13F filings for Q2 2026, worth $2.75B in total; superinvestors Coatue Management and Duquesne Family Office hold it.
13F holders, Q4 2025
Institutional positions in Caris Life Sciences, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 186
- +50 vs. Q3 2025
- Shares held
- 145.3M
- +32.6M (+29.0%) vs. Q3 2025
- Total value
- $3.92B
- +$531.3M (+15.7%) vs. Q3 2025
- New holders
- 77
- 63 more added
- Sold out
- 27
- 30 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CAI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 247 | $2.75B |
| Q1 2026 | 202 | $2.80B |
| Q4 2025 | 186 | $3.92B |
| Q3 2025 | 138 | $3.41B |
| Q2 2025 | 116 | $2.92B |
| Q1 2025 | 0 | $0 |
| Q4 2024 | 0 | $0 |
| Q3 2024 | 0 | $0 |
| Q2 2024 | 0 | $0 |
| Q1 2024 | 0 | $0 |
| Q4 2023 | 0 | $0 |
| Q3 2023 | 0 | $0 |
| Q2 2023 | 0 | $0 |
| Q1 2023 | 0 | $0 |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Caris Life Sciences, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| J. H. Whitney Equity Partners VI, LLC | 20,256,615 | $546.5M | 100.00% | +20,256,615 | New |
| Sixth Street Partners Management Company, L.P. | 19,385,399 | $523.0M | 53.72% | −5,000,000−20.5% | Reduced |
| FMR LLC | 14,217,768 | $383.6M | 0.02% | +4,584,333+47.6% | Added |
| Coatue Management LLCSuperinvestorCoatue Management | 9,819,992 | $264.9M | 0.66% | −322,206−3.2% | Reduced |
| T. Rowe Price Investment Management, Inc. | 9,205,959 | $248.4M | 0.16% | +1,180,200+14.7% | Added |
| Braidwell LP | 7,816,142 | $210.9M | 6.74% | +500,000+6.8% | Added |
| PointState Capital LP | 6,718,707 | $181.3M | 3.10% | +2,834,986+73.0% | Added |
| Price T Rowe Associates Inc | 4,827,965 | $130.3M | 0.01% | −2,096,780−30.3% | Reduced |
| Neuberger Berman Group LLC | 3,800,922 | $102.5M | 0.08% | −544,120−12.5% | Reduced |
| Millennium Management LLC | 3,652,647 | $98.5M | 0.07% | −285,425−7.2% | Reduced |
| OrbiMed Advisors LLC | 3,116,011 | $84.1M | 1.72% | +81,153+2.7% | Added |
| Citadel Advisors LLC | 3,113,956 | $84.0M | 0.06% | +3,113,956 | New |
| JPMorgan Chase & Co | 2,445,281 | $66.0M | 0.00% | +1,587,176+185.0% | Added |
| BlackRock, Inc. | 2,371,236 | $64.0M | 0.00% | +1,724,155+266.5% | Added |
| UBS Group AG | 2,183,980 | $58.9M | 0.01% | +1,948,107+825.9% | Added |
| Point72 Asset Management, L.P. | 1,864,860 | $50.3M | 0.08% | +1,618,236+656.2% | Added |
| Morgan Stanley | 1,794,991 | $48.4M | 0.00% | +260,568+17.0% | Added |
| Balyasny Asset Management LLC | 1,660,280 | $44.8M | 0.08% | +1,653,363+23,902.9% | Added |
| Longaeva Partners L.P. | 1,509,745 | $40.7M | 4.84% | +223,777+17.4% | Added |
| Ameriprise Financial Inc | 1,505,080 | $40.6M | 0.01% | −174,388−10.4% | Reduced |
| UBS Asset Management Americas Inc | 1,470,295 | $39.7M | 0.01% | +354,104+31.7% | Added |
| Canada Pension Plan Investment Board | 1,464,558 | $39.5M | 0.03% | +141,806+10.7% | Added |
| Clearbridge Investments, LLC | 1,416,207 | $38.2M | 0.03% | +34,977+2.5% | Added |
| Perceptive Advisors LLC | 1,136,206 | $30.7M | 0.56% | +38,043+3.5% | Added |
| FIL Ltd | 1,122,775 | $30.3M | 0.02% | +896,855+397.0% | Added |
| Bank of America Corp | 1,122,748 | $30.3M | 0.00% | +693,270+161.4% | Added |
| Invesco Ltd. | 1,033,115 | $27.9M | 0.00% | +229,313+28.5% | Added |
| Marshall Wace, LLP | 1,002,734 | $27.1M | 0.03% | +919,759+1,108.5% | Added |
| Massachusetts Financial Services Co | 941,639 | $25.4M | 0.01% | −29,691−3.1% | Reduced |
| Champlain Investment Partners, LLC | 939,365 | $25.3M | 0.26% | +939,365 | New |
| Ghisallo Capital Management LLC | 845,332 | $22.8M | 1.02% | −202,831−19.4% | Reduced |
| TD Asset Management Inc | 773,852 | $20.9M | 0.02% | +551,516+248.1% | Added |
| Woodline Partners LP | 723,163 | $19.5M | 0.08% | 00.0% | Unchanged |
| Rock Springs Capital Management LP | 687,500 | $18.5M | 0.95% | −106,151−13.4% | Reduced |
| BNP Paribas Arbitrage, SA | 685,826 | $18.5M | 0.01% | +684,626+57,052.2% | Added |
| Zevenbergen Capital Investments LLC | 543,185 | $14.7M | 0.33% | +543,185 | New |
| Seven Grand Managers, LLC | 495,095 | $13.4M | 1.02% | +395,095+395.1% | Added |
| ARK Investment Management LLCSuperinvestorARK Invest | 408,725 | $11.0M | 0.07% | +163,375+66.6% | Added |
| Geode Capital Management, LLC | 372,979 | $10.1M | 0.00% | −25,349−6.4% | Reduced |
| Goldman Sachs Group Inc | 350,142 | $9.45M | 0.00% | +67,933+24.1% | Added |
| Renaissance Technologies LLC | 329,900 | $8.90M | 0.01% | +104,800+46.6% | Added |
| Meridiem Capital Partners LP | 278,063 | $7.50M | 0.47% | +278,063 | New |
| Franklin Resources Inc | 268,615 | $7.25M | 0.00% | +51,651+23.8% | Added |
| State Street Corp | 260,645 | $7.03M | 0.00% | +105,305+67.8% | Added |
| Schonfeld Strategic Advisors LLC | 247,407 | $6.68M | 0.03% | +247,407 | New |
| Lazard Asset Management LLC | 242,779 | $6.55M | 0.01% | −34,758−12.5% | Reduced |
| Holocene Advisors, LP | 237,897 | $6.42M | 0.01% | +66,770+39.0% | Added |
| Picton Mahoney Asset Management | 218,305 | $5.89M | 0.06% | +212,095+3,415.4% | Added |
| Qube Research & Technologies Ltd | 206,993 | $5.58M | 0.01% | +174,241+532.0% | Added |
| Worldquant Millennium Advisors LLC | 188,861 | $5.10M | 0.02% | +178,769+1,771.4% | Added |
| Tudor Investment Corp Et Al | 182,382 | $4.92M | 0.03% | −82,169−31.1% | Reduced |
| Jane Street Group, LLC | 170,997 | $4.61M | 0.01% | +156,402+1,071.6% | Added |
| Walleye Capital LLC | 162,915 | $4.40M | 0.03% | −157,754−49.2% | Reduced |
| Oddo BHF Asset Management SAS | 162,313 | $4.38M | 0.16% | +162,313 | New |
| State of Wisconsin Investment Board | 150,000 | $4.05M | 0.01% | 00.0% | Unchanged |
| Creative Planning | 149,856 | $4.04M | 0.00% | +149,856 | New |
| Parkman Healthcare Partners LLC | 125,000 | $3.37M | 0.32% | +125,000 | New |
| HRT Financial LP | 122,939 | $3.32M | 0.01% | +122,939 | New |
| Norges Bank | 110,294 | $2.98M | 0.00% | +110,294 | New |
| Jump Financial, LLC | 103,005 | $2.78M | 0.03% | +103,005 | New |
| Manufacturers Life Insurance Company, The | 101,816 | $2.78M | 0.00% | −8,268−7.5% | Reduced |
| Raymond James Financial Inc | 97,518 | $2.63M | 0.00% | +2,630+2.8% | Added |
| TD Waterhouse Canada Inc. | 92,653 | $2.50M | 0.02% | +92,653 | New |
| Pura Vida Investments, LLC | 89,940 | $2.43M | 9.07% | 00.0% | Unchanged |
| Trexquant Investment LP | 82,705 | $2.23M | 0.02% | +82,705 | New |
| Dark Forest Capital Management LP | 78,163 | $2.11M | 0.10% | +46,506+146.9% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 75,330 | $2.03M | 0.00% | +15,778+26.5% | Added |
| Burkehill Global Management, LP | 75,000 | $2.02M | 0.13% | 00.0% | Unchanged |
| Engineers Gate Manager LP | 71,403 | $1.93M | 0.02% | +49,375+224.1% | Added |
| Gotham Asset Management, LLC | 67,186 | $1.81M | 0.01% | +33,983+102.3% | Added |
| Quantinno Capital Management LP | 64,922 | $1.75M | 0.00% | −7,301−10.1% | Reduced |
| Squarepoint Ops LLC | 64,397 | $1.74M | 0.00% | +64,397 | New |
| Hamilton Lane Advisors LLC | 58,725 | $1.58M | 0.87% | +58,725 | New |
| Nikko Asset Management Americas, Inc. | 54,719 | $1.48M | 0.02% | +7,348+15.5% | Added |
| Barclays PLC | 54,117 | $1.46M | 0.00% | +50,940+1,603.4% | Added |
| Caption Management, LLC | 50,888 | $1.37M | 0.06% | +50,888 | New |
| Bank of New York Mellon Corp | 50,403 | $1.36M | 0.00% | +25,534+102.7% | Added |
| Element Capital Management LLC | 50,000 | $1.35M | 0.70% | +50,000 | New |
| China Universal Asset Management Co., Ltd. | 45,976 | $1.24M | 0.10% | +45,976 | New |
| Mangrove Partners | 42,483 | $1.15M | 0.09% | +42,483 | New |
| VARCOV Co. | 40,037 | $1.08M | 0.43% | +40,037 | New |
| Maven Securities LTD | 40,000 | $1.08M | 0.14% | +40,000 | New |
| Northern Trust Corp | 36,948 | $996.9K | 0.00% | −8,647−19.0% | Reduced |
| Voloridge Investment Management, LLC | 35,050 | $945.6K | 0.00% | +35,050 | New |
| Vanguard Group Inc | 33,505 | $904.0K | 0.00% | −142,039−80.9% | Reduced |
| Envestnet Asset Management Inc | 31,029 | $837.2K | 0.00% | +31,029 | New |
| Citigroup Inc | 30,725 | $829.0K | 0.00% | −17,720−36.6% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 30,157 | $813.6K | 0.00% | +30,157 | New |
| Bessemer Group Inc | 26,670 | $719.0K | 0.00% | +26,670 | New |
| Group One Trading, L.P. | 26,343 | $710.7K | 0.02% | +26,343 | New |
| LPL Financial LLC | 25,711 | $693.7K | 0.00% | +9,720+60.8% | Added |
| Deutsche Bank AG | 25,290 | $682.3K | 0.00% | 00.0% | Unchanged |
| PEAK6 LLC | 24,800 | $669.1K | 0.02% | +24,800 | New |
| SEI Investments Co | 24,451 | $659.7K | 0.00% | +24,451 | New |
| Sandia Investment Management LP | 23,600 | $636.7K | 1.59% | +15,000+174.4% | Added |
| Rhumbline Advisers | 23,381 | $630.8K | 0.00% | +1,884+8.8% | Added |
| WPWealth LLP | 23,025 | $621.2K | 0.10% | −110.0% | Reduced |
| Nuveen, LLC | 22,413 | $604.7K | 0.00% | 00.0% | Unchanged |
| PDT Partners, LLC | 22,016 | $594.0K | 0.04% | +22,016 | New |
| Oak Ridge Investments LLC | 21,820 | $588.7K | 0.04% | +21,820 | New |