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Caris Life Sciences, Inc.

CAI
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0002019410

In the last 90 days, Caris Life Sciences, Inc. insiders filed 1 open-market purchase and 3 sales; 247 institutions reported holding it in 13F filings for Q2 2026, worth $2.75B in total; superinvestors Coatue Management and Duquesne Family Office hold it.

Q4 2025 vs. Q3 2025

How the institutions holding Caris Life Sciences, Inc. changed between Q3 2025 and Q4 2025.

All holders in Q4 2025All holders in Q3 2025

13F holders of CAI: Q3 2025 compared with Q4 2025
MeasureQ3 2025Of which not filed for Q4 2025Q4 2025Change
Holders1382186+50
Shares113.4M725.5K145.3M+32.6M (+29.0%)
Value$3.41B$21.9M$3.92B+$531.3M (+15.7%)

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (77)

Institutions that held Caris Life Sciences, Inc. at the end of Q4 2025 but not at the end of Q3 2025.

Institutions new to CAI in Q4 2025
InstitutionSharesValue% of portfolio
J. H. Whitney Equity Partners VI, LLC20,256,615$546.5M100.00%
Citadel Advisors LLC3,113,956$84.0M0.06%
Champlain Investment Partners, LLC939,365$25.3M0.26%
Zevenbergen Capital Investments LLC543,185$14.7M0.33%
Meridiem Capital Partners LP278,063$7.50M0.47%
Schonfeld Strategic Advisors LLC247,407$6.68M0.03%
Oddo BHF Asset Management SAS162,313$4.38M0.16%
Creative Planning149,856$4.04M0.00%
Parkman Healthcare Partners LLC125,000$3.37M0.32%
HRT Financial LP122,939$3.32M0.01%
Norges Bank110,294$2.98M0.00%
Jump Financial, LLC103,005$2.78M0.03%
TD Waterhouse Canada Inc.92,653$2.50M0.02%
Trexquant Investment LP82,705$2.23M0.02%
Squarepoint Ops LLC64,397$1.74M0.00%
Hamilton Lane Advisors LLC58,725$1.58M0.87%
Caption Management, LLC50,888$1.37M0.06%
Element Capital Management LLC50,000$1.35M0.70%
China Universal Asset Management Co., Ltd.45,976$1.24M0.10%
Mangrove Partners42,483$1.15M0.09%
VARCOV Co.40,037$1.08M0.43%
Maven Securities LTD40,000$1.08M0.14%
Voloridge Investment Management, LLC35,050$945.6K0.00%
Envestnet Asset Management Inc31,029$837.2K0.00%
Mirae Asset Global ETFs Holdings Ltd.30,157$813.6K0.00%
Bessemer Group Inc26,670$719.0K0.00%
Group One Trading, L.P.26,343$710.7K0.02%
PEAK6 LLC24,800$669.1K0.02%
SEI Investments Co24,451$659.7K0.00%
PDT Partners, LLC22,016$594.0K0.04%
Oak Ridge Investments LLC21,820$588.7K0.04%
Diversified Trust Co20,000$539.6K0.01%
Magnetar Financial LLC17,493$472.0K0.00%
Boothbay Fund Management, LLC16,490$444.9K0.01%
Gsa Capital Partners LLP15,235$411.0K0.04%
Mirae Asset Global Investments Co., Ltd.13,711$369.9K0.00%
Victory Capital Management Inc13,263$357.8K0.00%
Lighthouse Investment Partners, LLC13,251$357.5K0.01%
New York State Common Retirement Fund12,900$348.0K0.00%
ProShare Advisors LLC12,462$336.2K0.00%
Temasek Holdings (Private) Ltd12,235$330.1K0.00%
Michael & Susan Dell Foundation12,235$330.1K0.01%
Axq Capital, LP12,212$329.5K0.07%
Clal Insurance Enterprises Holdings Ltd11,930$322.0K0.00%
Northwest & Ethical Investments L.P.10,600$289.6K0.01%
Knollwood Investment Advisory, LLC10,445$281.8K0.03%
Lykos Global Management, LP10,000$269.8K0.19%
Brevan Howard Capital Management LP9,767$263.5K0.01%
HSBC Holdings PLC9,601$260.7K0.00%
Summit Trail Advisors, LLC9,292$250.7K0.00%
Courier Capital LLC8,550$230.7K0.01%
Occudo Quantitative Strategies LP8,355$225.4K0.02%
Federation des caisses Desjardins du Quebec7,925$213.8K0.00%
GF Fund Management Co. Ltd.5,543$149.6K0.00%
Adams Street Partners LLC4,894$132.0K0.05%
Quantbot Technologies LP4,622$124.7K0.00%
Aquatic Capital Management LLC3,817$103.0K0.00%
Federated Hermes, Inc.3,000$80.9K0.00%
Aster Capital Management (DIFC) Ltd2,488$67.1K0.03%
Olistico Wealth, LLC1,152$31.1K0.02%
MAI Capital Management1,000$27.0K0.00%
Daiwa Securities Group Inc.850$23.0K0.00%
Los Angeles Capital Management LLC565$17.6K0.00%
Trust Co of Vermont330$8.90K0.00%
Versant Capital Management, Inc146$3.94K0.00%
Ancora Advisors, LLC145$3.91K0.00%
GAMMA Investing LLC97$2.62K0.00%
Cornerstone Planning Group LLC78$2.07K0.00%
Rockefeller Capital Management L.P.35$9440.00%
SageView Advisory Group, LLC32$8640.00%
Farther Finance Advisors, LLC29$7820.00%
Umb Bank N A6$1620.00%
Rothschild Investment LLC3$810.00%
IFP Advisors, Inc3$810.00%
Allworth Financial LP2$540.00%
DekaBank Deutsche Girozentrale146,100$00.00%
Covestor Ltd16$00.00%

Sold out (27)

Institutions that held Caris Life Sciences, Inc. at the end of Q3 2025 and filed for Q4 2025 without it.

Institutions that sold out of CAI in Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
Silver Lake Group, L.L.C.5,291,006$160.1M
Alyeska Investment Group, L.P.1,101,071$33.3M
Lord, Abbett & Co. LLC850,000$25.7M
Janus Henderson Group PLC664,438$20.1M
First Light Asset Management, LLC403,924$11.9M
Freestone Grove Partners LP251,389$7.60M
Jennison Associates LLC84,459$2.55M
Soros Fund Management LLCSuperinvestorSoros Fund Management55,650$1.68M
SRS Investment Management, LLC50,000$1.51M
D. E. Shaw & Co., Inc.49,785$1.51M
Verition Fund Management LLC30,910$935.0K
Susquehanna International Group, LLP28,988$876.9K
XTX Topco Ltd28,081$849.5K
Atika Capital Management LLC25,000$756.3K
Park Avenue Securities LLC20,730$627.0K
Ieq Capital, LLC17,141$518.5K
Man Group plc16,078$486.4K
Harbor Investment Advisory, LLC15,650$473.4K
Omers Administration Corp8,200$248.1K
American Century Companies Inc6,865$207.7K
SummitTX Capital, L.P.6,736$203.8K
Wealthcare Advisory Partners LLC6,666$201.6K
Nomura Asset Management Co Ltd562$17.0K
Caitong International Asset Management Co., Ltd208$6.29K
Massmutual Trust Co FSB5$151
Tortoise Investment Management, LLC1$30
Rakuten Investment Management, Inc.14,518–

Not filed for Q4 2025 yet (2)

Institutions that held Caris Life Sciences, Inc. at the end of Q3 2025 and haven't filed a 13F for Q4 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding CAI in Q3 2025 that haven't filed for Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
Point72 (DIFC) Ltd654,792$19.8M
Cubist Systematic Strategies, LLC70,731$2.14M