Caris Life Sciences, Inc.
CAI- Exchange
- Nasdaq
- Industry
- Services-Medical Laboratories
- SEC CIK
- 0002019410
In the last 90 days, Caris Life Sciences, Inc. insiders filed 1 open-market purchase and 3 sales; 247 institutions reported holding it in 13F filings for Q2 2026, worth $2.75B in total; superinvestors Coatue Management and Duquesne Family Office hold it.
13F holders, Q1 2026
Institutional positions in Caris Life Sciences, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 202
- +22 vs. Q4 2025
- Shares held
- 156.9M
- +11.7M (+8.1%) vs. Q4 2025
- Total value
- $2.80B
- −$1.11B (−28.4%) vs. Q4 2025
- New holders
- 57
- 88 more added
- Sold out
- 35
- 38 more reduced
6 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CAI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 247 | $2.75B |
| Q1 2026 | 202 | $2.80B |
| Q4 2025 | 186 | $3.92B |
| Q3 2025 | 138 | $3.41B |
| Q2 2025 | 116 | $2.92B |
| Q1 2025 | 0 | $0 |
| Q4 2024 | 0 | $0 |
| Q3 2024 | 0 | $0 |
| Q2 2024 | 0 | $0 |
| Q1 2024 | 0 | $0 |
| Q4 2023 | 0 | $0 |
| Q3 2023 | 0 | $0 |
| Q2 2023 | 0 | $0 |
| Q1 2023 | 0 | $0 |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Caris Life Sciences, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 30,785,585 | $550.4M | 0.03% | +16,567,817+116.5% | Added |
| J. H. Whitney Equity Partners VI, LLC | 18,256,615 | $326.4M | 100.00% | −2,000,000−9.9% | Reduced |
| Sixth Street Partners Management Company, L.P. | 14,385,399 | $257.2M | 36.19% | −5,000,000−25.8% | Reduced |
| Coatue Management LLCSuperinvestorCoatue Management | 9,819,992 | $175.6M | 0.60% | 00.0% | Unchanged |
| Braidwell LP | 8,009,447 | $143.2M | 4.78% | +193,305+2.5% | Added |
| PointState Capital LP | 7,360,446 | $131.6M | 3.06% | +641,739+9.6% | Added |
| T. Rowe Price Investment Management, Inc. | 5,588,257 | $99.9M | 0.07% | −3,617,702−39.3% | Reduced |
| BlackRock, Inc. | 4,857,112 | $86.8M | 0.00% | +2,485,876+104.8% | Added |
| Price T Rowe Associates Inc | 4,371,771 | $78.2M | 0.01% | −456,194−9.4% | Reduced |
| Vanguard Portfolio Management LLC | 3,758,462 | $67.2M | 0.00% | +3,758,462 | New |
| Neuberger Berman Group LLC | 3,590,586 | $64.2M | 0.05% | −210,336−5.5% | Reduced |
| Vanguard Capital Management LLC | 3,329,021 | $59.5M | 0.00% | +3,329,021 | New |
| JPMorgan Chase & Co | 3,460,215 | $58.3M | 0.00% | +1,014,934+41.5% | Added |
| OrbiMed Advisors LLC | 2,806,811 | $50.2M | 1.14% | −309,200−9.9% | Reduced |
| UBS Group AG | 2,745,811 | $49.1M | 0.01% | +561,831+25.7% | Added |
| Los Angeles Capital Management LLC | 2,289,602 | $40.9M | 0.16% | +2,289,037+405,139.3% | Added |
| Duquesne Family Office LLCSuperinvestorDuquesne Family Office | 1,894,450 | $33.9M | 1.15% | +1,894,450 | New |
| BNP Paribas Arbitrage, SA | 1,614,286 | $28.9M | 0.02% | +928,460+135.4% | Added |
| Clearbridge Investments, LLC | 1,551,774 | $27.7M | 0.02% | +135,567+9.6% | Added |
| FIL Ltd | 1,546,091 | $27.6M | 0.02% | +423,316+37.7% | Added |
| Millennium Management LLC | 1,527,756 | $27.3M | 0.02% | −2,124,891−58.2% | Reduced |
| Canada Pension Plan Investment Board | 1,322,752 | $23.7M | 0.02% | −141,806−9.7% | Reduced |
| Invesco Ltd. | 1,222,278 | $21.9M | 0.00% | +189,163+18.3% | Added |
| Champlain Investment Partners, LLC | 1,207,963 | $21.6M | 0.27% | +268,598+28.6% | Added |
| Capital World Investors | 1,180,173 | $21.1M | 0.00% | +1,180,173 | New |
| UBS Asset Management Americas Inc | 1,149,133 | $20.5M | 0.00% | −321,162−21.8% | Reduced |
| Morgan Stanley | 1,079,417 | $19.3M | 0.00% | −715,574−39.9% | Reduced |
| State Street Corp | 984,953 | $17.6M | 0.00% | +724,308+277.9% | Added |
| Point72 Asset Management, L.P. | 918,331 | $16.4M | 0.03% | −946,529−50.8% | Reduced |
| Geode Capital Management, LLC | 778,532 | $13.9M | 0.00% | +405,553+108.7% | Added |
| Gotham Asset Management, LLC | 744,426 | $13.3M | 0.04% | +677,240+1,008.0% | Added |
| Woodline Partners LP | 723,163 | $12.9M | 0.05% | 00.0% | Unchanged |
| TD Asset Management Inc | 670,388 | $12.0M | 0.01% | −103,464−13.4% | Reduced |
| Nuveen, LLC | 663,578 | $11.9M | 0.00% | +641,165+2,860.7% | Added |
| Zevenbergen Capital Investments LLC | 610,233 | $10.9M | 0.31% | +67,048+12.3% | Added |
| SEI Investments Co | 598,712 | $10.7M | 0.01% | +574,261+2,348.6% | Added |
| Rock Springs Capital Management LP | 563,000 | $10.1M | 0.59% | −124,500−18.1% | Reduced |
| Bank of America Corp | 523,268 | $9.36M | 0.00% | −599,480−53.4% | Reduced |
| Trexquant Investment LP | 490,536 | $8.77M | 0.06% | +407,831+493.1% | Added |
| Renaissance Technologies LLC | 449,900 | $8.04M | 0.01% | +120,000+36.4% | Added |
| Goldman Sachs Group Inc | 410,340 | $7.34M | 0.00% | +60,198+17.2% | Added |
| Ameriprise Financial Inc | 408,079 | $7.30M | 0.00% | −1,097,001−72.9% | Reduced |
| Lazard Asset Management LLC | 305,911 | $5.47M | 0.01% | +63,132+26.0% | Added |
| Picton Mahoney Asset Management | 278,977 | $4.99M | 0.05% | +60,672+27.8% | Added |
| Massachusetts Financial Services Co | 267,950 | $4.79M | 0.00% | −673,689−71.5% | Reduced |
| Ghisallo Capital Management LLC | 250,000 | $4.47M | 0.12% | −595,332−70.4% | Reduced |
| Federated Hermes, Inc. | 239,150 | $4.28M | 0.01% | +236,150+7,871.7% | Added |
| Bank of New York Mellon Corp | 231,661 | $4.14M | 0.00% | +181,258+359.6% | Added |
| Parkman Healthcare Partners LLC | 229,912 | $4.11M | 0.43% | +104,912+83.9% | Added |
| Arrowstreet Capital, Limited Partnership | 210,593 | $3.77M | 0.00% | +210,593 | New |
| Worldquant Millennium Advisors LLC | 194,710 | $3.48M | 0.01% | +5,849+3.1% | Added |
| Qube Research & Technologies Ltd | 187,480 | $3.35M | 0.00% | −19,513−9.4% | Reduced |
| Northern Trust Corp | 174,065 | $3.11M | 0.00% | +137,117+371.1% | Added |
| Manufacturers Life Insurance Company, The | 153,512 | $2.74M | 0.00% | +51,696+50.8% | Added |
| Quantinno Capital Management LP | 140,909 | $2.52M | 0.00% | +75,987+117.0% | Added |
| Aquatic Capital Management LLC | 140,097 | $2.50M | 0.07% | +136,280+3,570.3% | Added |
| State of Wisconsin Investment Board | 136,334 | $2.44M | 0.01% | −13,666−9.1% | Reduced |
| D. E. Shaw & Co., Inc. | 129,577 | $2.32M | 0.00% | +129,577 | New |
| Man Group plc | 128,971 | $2.31M | 0.00% | +128,971 | New |
| Oddo BHF Asset Management SAS | 109,539 | $1.96M | 0.08% | −52,774−32.5% | Reduced |
| Engineers Gate Manager LP | 102,757 | $1.84M | 0.02% | +31,354+43.9% | Added |
| Tudor Investment Corp Et Al | 100,327 | $1.79M | 0.01% | −82,055−45.0% | Reduced |
| Vanguard Fiduciary Trust Co | 96,581 | $1.73M | 0.00% | +96,581 | New |
| Raymond James Financial Inc | 90,233 | $1.61M | 0.00% | −7,285−7.5% | Reduced |
| Pura Vida Investments, LLC | 89,940 | $1.61M | 10.81% | 00.0% | Unchanged |
| Smartleaf Asset Management LLC | 94,051 | $1.58M | 0.06% | +94,051 | New |
| Alliancebernstein L.P. | 57,076 | $1.54M | 0.00% | +36,689+180.0% | Added |
| XTX Topco Ltd | 78,506 | $1.40M | 0.02% | +78,506 | New |
| Creative Planning | 77,998 | $1.39M | 0.00% | −71,858−48.0% | Reduced |
| Citadel Advisors LLC | 77,810 | $1.39M | 0.00% | −3,036,146−97.5% | Reduced |
| Citigroup Inc | 77,180 | $1.38M | 0.00% | +46,455+151.2% | Added |
| Burkehill Global Management, LP | 75,000 | $1.34M | 0.07% | 00.0% | Unchanged |
| Rhumbline Advisers | 74,622 | $1.33M | 0.00% | +51,241+219.2% | Added |
| Barclays PLC | 74,423 | $1.33M | 0.00% | +20,306+37.5% | Added |
| Twinbeech Capital LP | 58,100 | $1.04M | 0.11% | +58,100 | New |
| Sumitomo Mitsui Trust Holdings, Inc. | 56,744 | $1.01M | 0.00% | −18,586−24.7% | Reduced |
| Envestnet Asset Management Inc | 53,607 | $958.5K | 0.00% | +22,578+72.8% | Added |
| Susquehanna International Group, LLP | 53,066 | $948.8K | 0.00% | +53,066 | New |
| Natixis | 52,778 | $943.7K | 0.00% | +52,778 | New |
| China Universal Asset Management Co., Ltd. | 50,069 | $895.2K | 0.07% | +4,093+8.9% | Added |
| Renaissance Capital LLC | 43,484 | $826.2K | 0.60% | +29,055+201.4% | Added |
| New York State Common Retirement Fund | 45,700 | $817.1K | 0.00% | +32,800+254.3% | Added |
| Franklin Resources Inc | 44,975 | $804.2K | 0.00% | −223,640−83.3% | Reduced |
| Dark Forest Capital Management LP | 43,080 | $770.3K | 0.07% | −35,083−44.9% | Reduced |
| LPL Financial LLC | 42,041 | $751.7K | 0.00% | +16,330+63.5% | Added |
| CastleKnight Management LP | 41,036 | $733.7K | 0.03% | +30,600+293.2% | Added |
| Entropy Technologies, LP | 40,503 | $724.2K | 0.03% | +40,503 | New |
| Police & Firemen's Retirement System of New Jersey | 39,497 | $706.2K | 0.01% | +27,565+231.0% | Added |
| Treasurer of the State of North Carolina | 39,005 | $697.0K | 0.00% | +29,509+310.8% | Added |
| Americana Partners, LLC | 38,367 | $686.0K | 0.02% | +25,934+208.6% | Added |
| Deutsche Bank AG | 38,290 | $684.6K | 0.00% | +13,000+51.4% | Added |
| Nikko Asset Management Americas, Inc. | 36,133 | $646.1K | 0.01% | −18,586−34.0% | Reduced |
| Caption Management, LLC | 33,332 | $596.0K | 0.03% | −17,556−34.5% | Reduced |
| Diversified Trust Co | 32,500 | $581.1K | 0.01% | +12,500+62.5% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 30,350 | $542.7K | 0.00% | +193+0.6% | Added |
| AQR Capital Management LLC | 28,994 | $518.4K | 0.00% | +28,994 | New |
| Legal & General Group Plc | 28,781 | $514.6K | 0.00% | +21,900+318.3% | Added |
| Park Avenue Securities LLC | 27,937 | $500.0K | 0.00% | +27,937 | New |
| Dimensional Fund Advisors LP | 27,492 | $491.6K | 0.00% | +27,492 | New |
| Public Employees Retirement System of Ohio | 26,519 | $474.2K | 0.00% | +19,698+288.8% | Added |