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Caris Life Sciences, Inc.

CAI
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0002019410

In the last 90 days, Caris Life Sciences, Inc. insiders filed 1 open-market purchase and 3 sales; 247 institutions reported holding it in 13F filings for Q2 2026, worth $2.75B in total; superinvestors Coatue Management and Duquesne Family Office hold it.

13F holders, Q1 2026

Institutional positions in Caris Life Sciences, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
202
+22 vs. Q4 2025
Shares held
156.9M
+11.7M (+8.1%) vs. Q4 2025
Total value
$2.80B
−$1.11B (−28.4%) vs. Q4 2025
New holders
57
88 more added
Sold out
35
38 more reduced

6 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CAI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 202 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 0 institutionsQ2 2025: 116 institutionsQ3 2025: 138 institutionsQ4 2025: 186 institutionsQ1 2026: 202 institutionsQ2 2026: 247 institutions
Value heldQ1 2026: $2.80B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $0Q2 2025: $2.92BQ3 2025: $3.41BQ4 2025: $3.92BQ1 2026: $2.80BQ2 2026: $2.75B
Institutions holding CAI and their total value by quarter
QuarterHoldersValue
Q2 2026247$2.75B
Q1 2026202$2.80B
Q4 2025186$3.92B
Q3 2025138$3.41B
Q2 2025116$2.92B
Q1 20250$0
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Caris Life Sciences, Inc.; share changes are against Q4 2025.

Institutions holding CAI in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Oak Ridge Investments LLC26,106$466.8K0.03%+4,286+19.6%Added
Charles Schwab Investment Management Inc25,331$452.9K0.00%+25,331New
Russell Investments Group, Ltd.25,269$451.8K0.00%+23,274+1,166.6%Added
State Board of Administration of Florida Retirement System24,293$434.4K0.00%+24,293New
WPWealth LLP23,025$411.7K0.06%00.0%Unchanged
Edmond de Rothschild Holding S.A.22,615$404.4K0.01%+10,350+84.4%Added
Vanguard Asset Management, Ltd22,584$403.8K0.00%+22,584New
Axq Capital, LP22,125$395.6K0.05%+9,913+81.2%Added
PDT Partners, LLC22,016$393.6K0.02%00.0%Unchanged
Perbak Capital Partners LLP22,001$393.4K0.10%+14,150+180.2%Added
Amundi20,972$375.0K0.00%+20,972New
Verition Fund Management LLC20,000$357.6K0.00%+20,000New
MSA Advisors, LLC19,200$343.3K0.10%00.0%Unchanged
Courier Capital LLC19,000$339.7K0.02%+10,450+122.2%Added
Royal Bank of Canada18,651$333.0K0.00%+9,407+101.8%Added
Group One Trading, L.P.18,173$324.9K0.01%−8,170−31.0%Reduced
Wells Fargo & Company17,250$308.4K0.00%+8,255+91.8%Added
HSBC Holdings PLC16,494$294.0K0.00%+6,893+71.8%Added
TD Waterhouse Canada Inc.14,300$273.2K0.00%−78,353−84.6%Reduced
American Century Companies Inc14,940$267.1K0.00%+14,940New
Mirae Asset Global Investments Co., Ltd.14,717$263.1K0.00%+1,006+7.3%Added
Savant Capital, LLC13,803$246.8K0.00%+13,803New
Victory Capital Management Inc13,802$246.8K0.00%+539+4.1%Added
Natixis Advisors, L.P.13,759$246.0K0.00%+13,759New
Perigon Wealth Management, LLC13,500$241.4K0.00%+13,500New
Northwest & Ethical Investments L.P.12,500$237.6K0.01%+1,900+17.9%Added
IMC-Chicago, LLC12,919$231.0K0.00%+12,919New
ProShare Advisors LLC12,622$225.7K0.00%+160+1.3%Added
Jacobs Levy Equity Management, Inc12,340$220.6K0.00%+12,340New
Summit Trail Advisors, LLC12,317$220.2K0.00%+3,025+32.6%Added
Custom Index Systems, LLC12,280$219.6K0.10%+12,280New
Temasek Holdings (Private) Ltd12,235$218.8K0.00%00.0%Unchanged
Michael & Susan Dell Foundation12,235$218.8K0.01%00.0%Unchanged
Bessemer Group Inc11,880$212.0K0.00%−14,790−55.5%Reduced
Wedmont Private Capital10,715$209.1K0.01%+10,715New
Jones Financial Companies LLLP12,296$208.4K0.00%+12,271+49,084.0%Added
Triton Wealth Management, PLLC10,918$206.3K0.08%00.0%Unchanged
Xponance, Inc.10,921$195.3K0.00%+10,921New
Jefferies Financial Group Inc.10,745$192.1K0.00%+10,745New
Knollwood Investment Advisory, LLC10,445$186.8K0.02%00.0%Unchanged
Emerald Advisers, LLC10,422$186.3K0.01%+10,422New
Federation des caisses Desjardins du Quebec6,932$123.9K0.00%−993−12.5%Reduced
Bellevue Group AG6,418$114.8K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.6,337$113.3K0.00%+794+14.3%Added
Advisor Group Holdings, Inc.5,928$106.0K0.00%+1,839+45.0%Added
California State Teachers Retirement System5,002$89.4K0.00%+3,591+254.5%Added
Blue Owl Capital Holdings LP4,711$84.2K0.02%+4,711New
Quantbot Technologies LP3,855$68.9K0.00%−767−16.6%Reduced
MetLife Investment Management3,536$63.2K0.00%+1,882+113.8%Added
Quadrant Capital Group LLC2,884$51.6K0.00%+2,884New
Simplex Trading, LLC2,669$47.7K0.00%−1,930−42.0%Reduced
STRS Ohio2,179$39.0K0.00%+1,636+301.3%Added
Sterling Capital Management LLC1,927$34.5K0.00%+1,083+128.3%Added
Ancora Advisors, LLC1,923$34.4K0.00%+1,778+1,226.2%Added
Versant Capital Management, Inc1,753$31.3K0.00%+1,607+1,100.7%Added
Fifth Third Bancorp1,749$31.3K0.00%+1,749New
The PNC Financial Services Group, Inc.1,644$29.4K0.00%+1,469+839.4%Added
US Bancorp1,511$27.0K0.00%−11,478−88.4%Reduced
Olistico Wealth, LLC1,423$25.4K0.01%+271+23.5%Added
Bokf, NA1,131$20.2K0.00%00.0%Unchanged
MAI Capital Management1,035$18.5K0.00%+35+3.5%Added
SRS Capital Advisors, Inc.870$15.6K0.00%+776+825.5%Added
CWM, LLC866$15.5K0.00%+691+394.9%Added
Zions Bancorporation, National Association848$15.2K0.00%+848New
J.Safra Asset Management Corp702$12.6K0.00%+567+420.0%Added
Albion Financial Group678$12.1K0.00%+678New
CX Institutional684$12.0K0.00%+684New
GAMMA Investing LLC616$11.0K0.00%+519+535.1%Added
Vanguard Global Advisers, LLC525$9.39K0.00%+525New
Quent Capital, LLC516$9.23K0.00%+516New
SBI Securities Co., Ltd.444$7.94K0.00%−2−0.4%Reduced
Nisa Investment Advisors, LLC422$7.54K0.00%+422New
Brown Brothers Harriman & Co344$6.15K0.00%00.0%Unchanged
Covestor Ltd304$5.00K0.00%+288+1,800.0%Added
Signaturefd, LLC220$3.93K0.00%+220New
GWM Advisors LLC200$3.58K0.00%00.0%Unchanged
ORG Wealth Partners, LLC200$3.58K0.00%00.0%Unchanged
Owl Creek Wealth Partners LLC190$3.40K0.00%+190New
Larson Financial Group LLC152$2.72K0.00%+152New
Farther Finance Advisors, LLC132$2.52K0.00%+103+355.2%Added
Rockefeller Capital Management L.P.135$2.41K0.00%+100+285.7%Added
First Horizon Corp107$1.91K0.00%+107New
Advisory Services Network, LLC100$1.79K0.00%+100New
Tower Research Capital LLC (TRC)99$1.77K0.00%−41−29.3%Reduced
Financial Management Professionals, Inc.91$1.63K0.00%+20+28.2%Added
Cornerstone Planning Group LLC78$1.48K0.00%00.0%Unchanged
Atlantic Trust, LLC73$1.31K0.00%+73New
Allworth Financial LP59$1.05K0.00%+57+2,850.0%Added
Huntington National Bank36$6440.00%+36New
EverSource Wealth Advisors, LLC34$6080.00%+34New
Essential Partners LLC33$5900.00%+33New
Umb Bank N A30$5360.00%+24+400.0%Added
Massmutual Trust Co FSB29$5190.00%+29New
Caitong International Asset Management Co., Ltd24$4290.00%+24New
Rothschild Investment LLC19$3400.00%+16+533.3%Added
IFP Advisors, Inc6$1070.00%+3+100.0%Added
Freestone Grove Partners LP6$1070.00%+6New
Cedar Mountain Advisors, LLC5$890.00%00.0%Unchanged
Wealth Preservation Advisors, LLC3$540.00%+3New
Transamerica Financial Advisors, Inc.3$530.00%+3New