Caris Life Sciences, Inc.
CAI- Exchange
- Nasdaq
- Industry
- Services-Medical Laboratories
- SEC CIK
- 0002019410
In the last 90 days, Caris Life Sciences, Inc. insiders filed 1 open-market purchase and 3 sales; 247 institutions reported holding it in 13F filings for Q2 2026, worth $2.75B in total; superinvestors Coatue Management and Duquesne Family Office hold it.
13F holders, Q4 2025
Institutional positions in Caris Life Sciences, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 186
- +50 vs. Q3 2025
- Shares held
- 145.3M
- +32.6M (+29.0%) vs. Q3 2025
- Total value
- $3.92B
- +$531.3M (+15.7%) vs. Q3 2025
- New holders
- 77
- 63 more added
- Sold out
- 27
- 30 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CAI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 247 | $2.75B |
| Q1 2026 | 202 | $2.80B |
| Q4 2025 | 186 | $3.92B |
| Q3 2025 | 138 | $3.41B |
| Q2 2025 | 116 | $2.92B |
| Q1 2025 | 0 | $0 |
| Q4 2024 | 0 | $0 |
| Q3 2024 | 0 | $0 |
| Q2 2024 | 0 | $0 |
| Q1 2024 | 0 | $0 |
| Q4 2023 | 0 | $0 |
| Q3 2023 | 0 | $0 |
| Q2 2023 | 0 | $0 |
| Q1 2023 | 0 | $0 |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Caris Life Sciences, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Alliancebernstein L.P. | 20,387 | $550.0K | 0.00% | −1,181,598−98.3% | Reduced |
| Diversified Trust Co | 20,000 | $539.6K | 0.01% | +20,000 | New |
| MSA Advisors, LLC | 19,200 | $518.0K | 0.13% | 00.0% | Unchanged |
| Magnetar Financial LLC | 17,493 | $472.0K | 0.00% | +17,493 | New |
| Boothbay Fund Management, LLC | 16,490 | $444.9K | 0.01% | +16,490 | New |
| Davy Global Fund Management Ltd | 15,546 | $419.4K | 0.03% | +7,220+86.7% | Added |
| Gsa Capital Partners LLP | 15,235 | $411.0K | 0.04% | +15,235 | New |
| Renaissance Capital LLC | 14,429 | $389.3K | 0.28% | −14,031−49.3% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 13,711 | $369.9K | 0.00% | +13,711 | New |
| Victory Capital Management Inc | 13,263 | $357.8K | 0.00% | +13,263 | New |
| Lighthouse Investment Partners, LLC | 13,251 | $357.5K | 0.01% | +13,251 | New |
| US Bancorp | 12,989 | $350.4K | 0.00% | +267+2.1% | Added |
| New York State Common Retirement Fund | 12,900 | $348.0K | 0.00% | +12,900 | New |
| ProShare Advisors LLC | 12,462 | $336.2K | 0.00% | +12,462 | New |
| Americana Partners, LLC | 12,433 | $335.4K | 0.01% | 00.0% | Unchanged |
| Edmond de Rothschild Holding S.A. | 12,265 | $330.9K | 0.00% | +4,765+63.5% | Added |
| Temasek Holdings (Private) Ltd | 12,235 | $330.1K | 0.00% | +12,235 | New |
| Michael & Susan Dell Foundation | 12,235 | $330.1K | 0.01% | +12,235 | New |
| Axq Capital, LP | 12,212 | $329.5K | 0.07% | +12,212 | New |
| Clal Insurance Enterprises Holdings Ltd | 11,930 | $322.0K | 0.00% | +11,930 | New |
| Police & Firemen's Retirement System of New Jersey | 11,932 | $321.9K | 0.00% | +1,560+15.0% | Added |
| Northwest & Ethical Investments L.P. | 10,600 | $289.6K | 0.01% | +10,600 | New |
| Knollwood Investment Advisory, LLC | 10,445 | $281.8K | 0.03% | +10,445 | New |
| CastleKnight Management LP | 10,436 | $281.6K | 0.02% | 00.0% | Unchanged |
| Lykos Global Management, LP | 10,000 | $269.8K | 0.19% | +10,000 | New |
| Brevan Howard Capital Management LP | 9,767 | $263.5K | 0.01% | +9,767 | New |
| HSBC Holdings PLC | 9,601 | $260.7K | 0.00% | +9,601 | New |
| Treasurer of the State of North Carolina | 9,496 | $256.0K | 0.00% | −577−5.7% | Reduced |
| Summit Trail Advisors, LLC | 9,292 | $250.7K | 0.00% | +9,292 | New |
| Triton Wealth Management, PLLC | 10,918 | $250.6K | 0.09% | +413+3.9% | Added |
| Royal Bank of Canada | 9,244 | $250.0K | 0.00% | +4,953+115.4% | Added |
| Wells Fargo & Company | 8,995 | $242.7K | 0.00% | +7,225+408.2% | Added |
| Courier Capital LLC | 8,550 | $230.7K | 0.01% | +8,550 | New |
| Occudo Quantitative Strategies LP | 8,355 | $225.4K | 0.02% | +8,355 | New |
| Federation des caisses Desjardins du Quebec | 7,925 | $213.8K | 0.00% | +7,925 | New |
| Perbak Capital Partners LLP | 7,851 | $211.8K | 0.06% | −2,852−26.6% | Reduced |
| Legal & General Group Plc | 6,881 | $185.6K | 0.00% | +4,584+199.6% | Added |
| Public Employees Retirement System of Ohio | 6,821 | $184.0K | 0.00% | −176−2.5% | Reduced |
| Bellevue Group AG | 6,418 | $173.2K | 0.00% | −3,187−33.2% | Reduced |
| GF Fund Management Co. Ltd. | 5,543 | $149.6K | 0.00% | +5,543 | New |
| Adams Street Partners LLC | 4,894 | $132.0K | 0.05% | +4,894 | New |
| Quantbot Technologies LP | 4,622 | $124.7K | 0.00% | +4,622 | New |
| Simplex Trading, LLC | 4,599 | $124.1K | 0.00% | +616+15.5% | Added |
| Advisor Group Holdings, Inc. | 4,089 | $110.3K | 0.00% | +3,639+808.7% | Added |
| Aquatic Capital Management LLC | 3,817 | $103.0K | 0.00% | +3,817 | New |
| Federated Hermes, Inc. | 3,000 | $80.9K | 0.00% | +3,000 | New |
| Aster Capital Management (DIFC) Ltd | 2,488 | $67.1K | 0.03% | +2,488 | New |
| Russell Investments Group, Ltd. | 1,995 | $53.8K | 0.00% | 00.0% | Unchanged |
| MetLife Investment Management | 1,654 | $44.6K | 0.00% | +755+84.0% | Added |
| Amalgamated Bank | 1,471 | $40.0K | 0.00% | +8+0.5% | Added |
| California State Teachers Retirement System | 1,411 | $38.1K | 0.00% | +105+8.0% | Added |
| Olistico Wealth, LLC | 1,152 | $31.1K | 0.02% | +1,152 | New |
| Bokf, NA | 1,131 | $30.5K | 0.00% | 00.0% | Unchanged |
| Global Retirement Partners, LLC | 1,000 | $27.0K | 0.00% | +999+99,900.0% | Added |
| MAI Capital Management | 1,000 | $27.0K | 0.00% | +1,000 | New |
| Daiwa Securities Group Inc. | 850 | $23.0K | 0.00% | +850 | New |
| Sterling Capital Management LLC | 844 | $22.8K | 0.00% | +130+18.2% | Added |
| Comerica Bank | 689 | $18.6K | 0.00% | +27+4.1% | Added |
| Los Angeles Capital Management LLC | 565 | $17.6K | 0.00% | +565 | New |
| STRS Ohio | 543 | $14.7K | 0.00% | +7+1.3% | Added |
| SBI Securities Co., Ltd. | 446 | $12.0K | 0.00% | −780−63.6% | Reduced |
| Brown Brothers Harriman & Co | 344 | $9.28K | 0.00% | 00.0% | Unchanged |
| Trust Co of Vermont | 330 | $8.90K | 0.00% | +330 | New |
| GWM Advisors LLC | 200 | $5.40K | 0.00% | 00.0% | Unchanged |
| ORG Wealth Partners, LLC | 200 | $5.40K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 175 | $5.00K | 0.00% | −603−77.5% | Reduced |
| The PNC Financial Services Group, Inc. | 175 | $4.72K | 0.00% | −680−79.5% | Reduced |
| Versant Capital Management, Inc | 146 | $3.94K | 0.00% | +146 | New |
| Ancora Advisors, LLC | 145 | $3.91K | 0.00% | +145 | New |
| Tower Research Capital LLC (TRC) | 140 | $3.78K | 0.00% | +117+508.7% | Added |
| J.Safra Asset Management Corp | 135 | $3.64K | 0.00% | +114+542.9% | Added |
| GAMMA Investing LLC | 97 | $2.62K | 0.00% | +97 | New |
| SRS Capital Advisors, Inc. | 94 | $2.54K | 0.00% | −123−56.7% | Reduced |
| Cornerstone Planning Group LLC | 78 | $2.07K | 0.00% | +78 | New |
| Financial Management Professionals, Inc. | 71 | $1.92K | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 35 | $944 | 0.00% | +35 | New |
| SageView Advisory Group, LLC | 32 | $864 | 0.00% | +32 | New |
| Farther Finance Advisors, LLC | 29 | $782 | 0.00% | +29 | New |
| Jones Financial Companies LLLP | 25 | $675 | 0.00% | −115−82.1% | Reduced |
| Umb Bank N A | 6 | $162 | 0.00% | +6 | New |
| Cedar Mountain Advisors, LLC | 5 | $135 | 0.00% | 00.0% | Unchanged |
| Rothschild Investment LLC | 3 | $81 | 0.00% | +3 | New |
| IFP Advisors, Inc | 3 | $81 | 0.00% | +3 | New |
| Allworth Financial LP | 2 | $54 | 0.00% | +2 | New |
| DekaBank Deutsche Girozentrale | 146,100 | $0 | 0.00% | +146,100 | New |
| Covestor Ltd | 16 | $0 | 0.00% | +16 | New |
| Silver Lake Group, L.L.C. | 0 | $0 | 0.00% | −5,291,006−100.0% | Sold out |
| Alyeska Investment Group, L.P. | 0 | $0 | 0.00% | −1,101,071−100.0% | Sold out |
| Lord, Abbett & Co. LLC | 0 | $0 | 0.00% | −850,000−100.0% | Sold out |
| Janus Henderson Group PLC | 0 | $0 | 0.00% | −664,438−100.0% | Sold out |
| First Light Asset Management, LLC | 0 | $0 | 0.00% | −403,924−100.0% | Sold out |
| Freestone Grove Partners LP | 0 | $0 | 0.00% | −251,389−100.0% | Sold out |
| Jennison Associates LLC | 0 | $0 | 0.00% | −84,459−100.0% | Sold out |
| Soros Fund Management LLCSuperinvestorSoros Fund Management | 0 | $0 | 0.00% | −55,650−100.0% | Sold out |
| SRS Investment Management, LLC | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| D. E. Shaw & Co., Inc. | 0 | $0 | 0.00% | −49,785−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −30,910−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −28,988−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −28,081−100.0% | Sold out |
| Atika Capital Management LLC | 0 | $0 | 0.00% | −25,000−100.0% | Sold out |