Caris Life Sciences, Inc.

CAI

Exchange: Nasdaq
Industry: Services-Medical Laboratories
SEC CIK: 0002019410

SEC filings (opens in a new tab)

In the last 90 days, Caris Life Sciences, Inc. insiders filed 1 open-market purchase and 3 sales; 247 institutions reported holding it in 13F filings for Q2 2026, worth $2.75B in total; superinvestors Coatue Management and Duquesne Family Office hold it.

Q3 2025 vs. Q2 2025

How the institutions holding Caris Life Sciences, Inc. changed between Q2 2025 and Q3 2025.

All holders in Q3 2025 All holders in Q2 2025

13F holders of CAI: Q2 2025 compared with Q3 2025
Measure	Q2 2025	Of which not filed for Q3 2025	Q3 2025	Change
Holders	116	1	138	+23
Shares	109.3M	375.0K	113.4M	+4.45M (+4.1%)
Value	$2.92B	$10.0M	$3.41B	+$495.5M (+17.0%)

1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (53)

Institutions that held Caris Life Sciences, Inc. at the end of Q3 2025 but not at the end of Q2 2025.

Institutions new to CAI in Q3 2025
Institution	Shares	Value	% of portfolio
Lord, Abbett & Co. LLC	850,000	$25.7M	0.08%
UBS Group AG	235,873	$7.14M	0.00%
Renaissance Technologies LLC	225,100	$6.81M	0.01%
State Street Corp	155,340	$4.70M	0.00%
Quantinno Capital Management LP	72,223	$2.18M	0.01%
Nikko Asset Management Americas, Inc.	47,371	$1.43M	0.01%
Northern Trust Corp	45,595	$1.38M	0.00%
Gotham Asset Management, LLC	33,203	$1.00M	0.00%
Dark Forest Capital Management LP	31,657	$957.6K	0.04%
Verition Fund Management LLC	30,910	$935.0K	0.01%
Susquehanna International Group, LLP	28,988	$876.9K	0.00%
Renaissance Capital LLC	28,460	$860.9K	0.48%
XTX Topco Ltd	28,081	$849.5K	0.04%
Bank of New York Mellon Corp	24,869	$752.3K	0.00%
WPWealth LLP	23,036	$696.8K	0.11%
Nuveen, LLC	22,413	$678.0K	0.00%
Engineers Gate Manager LP	22,028	$666.3K	0.01%
Rhumbline Advisers	21,497	$650.3K	0.00%
Park Avenue Securities LLC	20,730	$627.0K	0.00%
Ieq Capital, LLC	17,141	$518.5K	0.00%
Man Group plc	16,078	$486.4K	0.00%
Harbor Investment Advisory, LLC	15,650	$473.4K	0.04%
Jane Street Group, LLC	14,595	$441.5K	0.00%
Americana Partners, LLC	12,433	$376.1K	0.01%
Perbak Capital Partners LLP	10,703	$323.8K	0.06%
Police & Firemen's Retirement System of New Jersey	10,372	$313.8K	0.00%
Worldquant Millennium Advisors LLC	10,092	$305.3K	0.00%
Treasurer of the State of North Carolina	10,073	$305.0K	0.00%
Davy Global Fund Management Ltd	8,326	$251.9K	0.02%
Omers Administration Corp	8,200	$248.1K	0.00%
Edmond de Rothschild Holding S.A.	7,500	$226.9K	0.00%
Public Employees Retirement System of Ohio	6,997	$211.7K	0.00%
American Century Companies Inc	6,865	$207.7K	0.00%
SummitTX Capital, L.P.	6,736	$203.8K	0.01%
Wealthcare Advisory Partners LLC	6,666	$201.6K	0.00%
Picton Mahoney Asset Management	6,210	$188.0K	0.00%
Russell Investments Group, Ltd.	1,995	$60.3K	0.00%
Amalgamated Bank	1,463	$44.0K	0.00%
California State Teachers Retirement System	1,306	$39.5K	0.00%
BNP Paribas Arbitrage, SA	1,200	$36.3K	0.00%
Bokf, NA	1,131	$34.2K	0.00%
MetLife Investment Management	899	$27.2K	0.00%
Sterling Capital Management LLC	714	$21.6K	0.00%
Comerica Bank	662	$20.0K	0.00%
STRS Ohio	536	$16.2K	0.00%
Brown Brothers Harriman & Co	344	$10.4K	0.00%
Caitong International Asset Management Co., Ltd	208	$6.29K	0.00%
Jones Financial Companies LLLP	140	$4.09K	0.00%
J.Safra Asset Management Corp	21	$635	0.00%
Massmutual Trust Co FSB	5	$151	0.00%
Tortoise Investment Management, LLC	1	$30	0.00%
Global Retirement Partners, LLC	1	$30	0.00%
Rakuten Investment Management, Inc.	14,518	–	–

Sold out (30)

Institutions that held Caris Life Sciences, Inc. at the end of Q2 2025 and filed for Q3 2025 without it.

Institutions that sold out of CAI in Q3 2025
Institution	Shares, Q2 2025	Value, Q2 2025
Capital World Investors	999,945	$26.7M
Citadel Advisors LLC	341,570	$9.13M
Summit Partners Public Asset Management, LLC	296,000	$7.91M
Adage Capital Partners GP, L.L.C.	150,000	$4.01M
Standard Life Aberdeen plc	117,841	$3.15M
HRT Financial LP	109,318	$2.92M
Blackstone Group Inc.	100,000	$2.67M
Healthcare of Ontario Pension Plan Trust Fund	100,000	$2.67M
Jain Global LLC	87,288	$2.33M
Limestone Investment Advisors LP	86,000	$2.30M
Harbert Fund Advisors, Inc.	80,000	$2.14M
Squarepoint Ops LLC	77,830	$2.08M
Davidson Kempner Capital Management LP	54,000	$1.44M
Winton Group Ltd	44,981	$1.20M
Principal Financial Group Inc	42,026	$1.12M
Pictet Asset Management Holding SA	34,815	$930.3K
Scientech Research LLC	30,727	$821.0K
Westfield Capital Management Co LP	30,000	$801.6K
Greenland Capital Management LP	26,504	$708.2K
Oxford Asset Management LLP	25,000	$668.0K
Boothbay Fund Management, LLC	16,880	$451.0K
Aristeia Capital LLC	16,383	$437.8K
Diametric Capital, LP	14,828	$396.2K
Federated Hermes, Inc.	14,200	$379.4K
HBK Investments L P	11,000	$293.9K
Quarry LP	10,623	$283.8K
Bank of Montreal	10,000	$267.2K
Weiss Asset Management LP	10,000	$267.2K
Sectoral Asset Management Inc	8,350	$223.1K
Olistico Wealth, LLC	1,032	$27.6K

Not filed for Q3 2025 yet (1)

Institutions that held Caris Life Sciences, Inc. at the end of Q2 2025 and haven't filed a 13F for Q3 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding CAI in Q2 2025 that haven't filed for Q3 2025
Institution	Shares, Q2 2025	Value, Q2 2025
Norges Bank	375,000	$10.0M