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Caris Life Sciences, Inc.

CAI
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0002019410

In the last 90 days, Caris Life Sciences, Inc. insiders filed 1 open-market purchase and 3 sales; 247 institutions reported holding it in 13F filings for Q2 2026, worth $2.75B in total; superinvestors Coatue Management and Duquesne Family Office hold it.

13F holders, Q3 2025

Institutional positions in Caris Life Sciences, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
138
+23 vs. Q2 2025
Shares held
113.4M
+4.45M (+4.1%) vs. Q2 2025
Total value
$3.41B
+$495.5M (+17.0%) vs. Q2 2025
New holders
53
45 more added
Sold out
30
19 more reduced

1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CAI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 138 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 0 institutionsQ2 2025: 116 institutionsQ3 2025: 138 institutionsQ4 2025: 186 institutionsQ1 2026: 202 institutionsQ2 2026: 247 institutions
Value heldQ3 2025: $3.41B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $0Q2 2025: $2.92BQ3 2025: $3.41BQ4 2025: $3.92BQ1 2026: $2.80BQ2 2026: $2.75B
Institutions holding CAI and their total value by quarter
QuarterHoldersValue
Q2 2026247$2.75B
Q1 2026202$2.80B
Q4 2025186$3.92B
Q3 2025138$3.41B
Q2 2025116$2.92B
Q1 20250$0
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Caris Life Sciences, Inc.; share changes are against Q2 2025.

Institutions holding CAI in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Balyasny Asset Management LLC6,917$209.2K0.00%−43,453−86.3%Reduced
American Century Companies Inc6,865$207.7K0.00%+6,865New
SummitTX Capital, L.P.6,736$203.8K0.01%+6,736New
Wealthcare Advisory Partners LLC6,666$201.6K0.00%+6,666New
Picton Mahoney Asset Management6,210$188.0K0.00%+6,210New
Royal Bank of Canada4,291$130.0K0.00%+3,470+422.7%Added
Simplex Trading, LLC3,983$120.0K0.00%+3,151+378.7%Added
Barclays PLC3,177$96.1K0.00%−6,823−68.2%Reduced
Legal & General Group Plc2,297$69.4K0.00%+1,297+129.7%Added
Russell Investments Group, Ltd.1,995$60.3K0.00%+1,995New
Wells Fargo & Company1,770$53.5K0.00%+470+36.2%Added
Amalgamated Bank1,463$44.0K0.00%+1,463New
California State Teachers Retirement System1,306$39.5K0.00%+1,306New
SBI Securities Co., Ltd.1,226$37.1K0.00%+1,068+675.9%Added
BNP Paribas Arbitrage, SA1,200$36.3K0.00%+1,200New
Bokf, NA1,131$34.2K0.00%+1,131New
MetLife Investment Management899$27.2K0.00%+899New
The PNC Financial Services Group, Inc.855$25.9K0.00%+655+327.5%Added
CWM, LLC778$24.0K0.00%+628+418.7%Added
Sterling Capital Management LLC714$21.6K0.00%+714New
Comerica Bank662$20.0K0.00%+662New
Nomura Asset Management Co Ltd562$17.0K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.450$16.9K0.00%−550−55.0%Reduced
STRS Ohio536$16.2K0.00%+536New
Brown Brothers Harriman & Co344$10.4K0.00%+344New
SRS Capital Advisors, Inc.217$6.57K0.00%+198+1,042.1%Added
Caitong International Asset Management Co., Ltd208$6.29K0.00%+208New
GWM Advisors LLC200$6.05K0.00%00.0%Unchanged
ORG Wealth Partners, LLC200$6.05K0.00%00.0%Unchanged
Jones Financial Companies LLLP140$4.09K0.00%+140New
Financial Management Professionals, Inc.71$2.15K0.00%+51+255.0%Added
Tower Research Capital LLC (TRC)23$6960.00%−2,085−98.9%Reduced
J.Safra Asset Management Corp21$6350.00%+21New
Cedar Mountain Advisors, LLC5$1510.00%00.0%Unchanged
Massmutual Trust Co FSB5$1510.00%+5New
Tortoise Investment Management, LLC1$300.00%+1New
Global Retirement Partners, LLC1$300.00%+1New
Rakuten Investment Management, Inc.14,518––+14,518New
Capital World Investors0$00.00%−999,945−100.0%Sold out
Citadel Advisors LLC0$00.00%−341,570−100.0%Sold out
Summit Partners Public Asset Management, LLC0$00.00%−296,000−100.0%Sold out
Adage Capital Partners GP, L.L.C.0$00.00%−150,000−100.0%Sold out
Standard Life Aberdeen plc0$00.00%−117,841−100.0%Sold out
HRT Financial LP0$00.00%−109,318−100.0%Sold out
Blackstone Group Inc.0$00.00%−100,000−100.0%Sold out
Healthcare of Ontario Pension Plan Trust Fund0$00.00%−100,000−100.0%Sold out
Jain Global LLC0$00.00%−87,288−100.0%Sold out
Limestone Investment Advisors LP0$00.00%−86,000−100.0%Sold out
Harbert Fund Advisors, Inc.0$00.00%−80,000−100.0%Sold out
Squarepoint Ops LLC0$00.00%−77,830−100.0%Sold out
Davidson Kempner Capital Management LP0$00.00%−54,000−100.0%Sold out
Winton Group Ltd0$00.00%−44,981−100.0%Sold out
Principal Financial Group Inc0$00.00%−42,026−100.0%Sold out
Pictet Asset Management Holding SA0$00.00%−34,815−100.0%Sold out
Scientech Research LLC0$00.00%−30,727−100.0%Sold out
Westfield Capital Management Co LP0$00.00%−30,000−100.0%Sold out
Greenland Capital Management LP0$00.00%−26,504−100.0%Sold out
Oxford Asset Management LLP0$00.00%−25,000−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−16,880−100.0%Sold out
Aristeia Capital LLC0$00.00%−16,383−100.0%Sold out
Diametric Capital, LP0$00.00%−14,828−100.0%Sold out
Federated Hermes, Inc.0$00.00%−14,200−100.0%Sold out
HBK Investments L P0$00.00%−11,000−100.0%Sold out
Quarry LP0$00.00%−10,623−100.0%Sold out
Bank of Montreal0$00.00%−10,000−100.0%Sold out
Weiss Asset Management LP0$00.00%−10,000−100.0%Sold out
Sectoral Asset Management Inc0$00.00%−8,350−100.0%Sold out
Olistico Wealth, LLC0$00.00%−1,032−100.0%Sold out
Norges Bank––––Not filed