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Axsome Therapeutics, Inc.

AXSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001579428

In the last 90 days, Axsome Therapeutics, Inc. insiders filed 0 open-market purchases and 2 sales; 505 institutions reported holding it in 13F filings for Q2 2026, worth $9.34B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Axsome Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
355
+10 vs. Q2 2025
Shares held
37.2M
−189.7K (−0.5%) vs. Q2 2025
Total value
$4.51B
+$613.1M (+15.7%) vs. Q2 2025
New holders
49
146 more added
Sold out
39
104 more reduced

3 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AXSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 355 institutions
Q1 2021: 184 institutionsQ2 2021: 176 institutionsQ3 2021: 171 institutionsQ4 2021: 167 institutionsQ1 2022: 175 institutionsQ2 2022: 174 institutionsQ3 2022: 188 institutionsQ4 2022: 219 institutionsQ1 2023: 197 institutionsQ2 2023: 231 institutionsQ3 2023: 227 institutionsQ4 2023: 245 institutionsQ1 2024: 259 institutionsQ2 2024: 257 institutionsQ3 2024: 280 institutionsQ4 2024: 292 institutionsQ1 2025: 353 institutionsQ2 2025: 348 institutionsQ3 2025: 355 institutionsQ4 2025: 399 institutionsQ1 2026: 410 institutionsQ2 2026: 505 institutions
Value heldQ3 2025: $4.51B
Q1 2021: $1.31BQ2 2021: $1.51BQ3 2021: $627.3MQ4 2021: $704.2MQ1 2022: $787.4MQ2 2022: $826.7MQ3 2022: $1.15BQ4 2022: $2.32BQ1 2023: $1.97BQ2 2023: $2.61BQ3 2023: $2.65BQ4 2023: $3.07BQ1 2024: $3.09BQ2 2024: $3.28BQ3 2024: $3.48BQ4 2024: $3.15BQ1 2025: $4.37BQ2 2025: $3.95BQ3 2025: $4.51BQ4 2025: $6.86BQ1 2026: $6.41BQ2 2026: $9.34B
Institutions holding AXSM and their total value by quarter
QuarterHoldersValue
Q2 2026505$9.34B
Q1 2026410$6.41B
Q4 2025399$6.86B
Q3 2025355$4.51B
Q2 2025348$3.95B
Q1 2025353$4.37B
Q4 2024292$3.15B
Q3 2024280$3.48B
Q2 2024257$3.28B
Q1 2024259$3.09B
Q4 2023245$3.07B
Q3 2023227$2.65B
Q2 2023231$2.61B
Q1 2023197$1.97B
Q4 2022219$2.32B
Q3 2022188$1.15B
Q2 2022174$826.7M
Q1 2022175$787.4M
Q4 2021167$704.2M
Q3 2021171$627.3M
Q2 2021176$1.51B
Q1 2021184$1.31B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Axsome Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding AXSM in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Campbell & CO Investment Adviser LLC6,077$738.1K0.06%−3,177−34.3%Reduced
Birchview Capital, LP6,000$728.7K0.55%00.0%Unchanged
Millennium Management LLC5,741$697.2K0.00%−24,878−81.3%Reduced
Rockefeller Capital Management L.P.5,737$696.8K0.00%+5,737New
Tocqueville Asset Management L.P.5,650$686.2K0.01%+450+8.7%Added
Cabot Wealth Management Inc5,560$675.3K0.07%+5,560New
Los Angeles Capital Management LLC5,555$674.7K0.00%+1,131+25.6%Added
Stifel Financial Corp5,507$668.8K0.00%+1,185+27.4%Added
Cerity Partners LLC5,404$656.3K0.00%−248−4.4%Reduced
CWM, LLC5,151$626.0K0.00%+2,146+71.4%Added
Prudential Financial Inc5,058$614.3K0.00%−17,750−77.8%Reduced
Yarbrough Capital, LLC5,054$613.8K0.02%00.0%Unchanged
Legato Capital Management LLC5,051$613.4K0.07%+750+17.4%Added
Henshaw Capital LLC5,036$611.6K0.02%−1,835−26.7%Reduced
Values First Advisors, Inc.4,882$592.9K0.32%−227−4.4%Reduced
Gsa Capital Partners LLP4,767$579.0K0.05%+4,767New
Victory Capital Management Inc4,740$575.7K0.00%−83−1.7%Reduced
Lion Street Advisors, LLC14,677$565.1K0.20%+5,619+62.0%Added
Cornerstone Select Advisors, LLC4,375$531.3K0.39%00.0%Unchanged
CIBC Bancorp USA Inc.4,314$523.9K0.00%+4,314New
Goodwin Investment Advisory4,241$515.1K0.55%00.0%Unchanged
Virtus Investment Advisers, Inc.4,183$508.0K0.15%00.0%Unchanged
Toroso Investments, LLC4,021$488.4K0.00%−204−4.8%Reduced
Farallon Capital Management, L.L.C.4,000$485.8K0.00%00.0%Unchanged
Mirador Capital Partners LP4,000$485.8K0.07%00.0%Unchanged
Aries Wealth Management4,000$485.8K0.11%00.0%Unchanged
Martingale Asset Management L P3,800$461.5K0.01%−10.0%Reduced
Pathstone Holdings, LLC3,799$461.4K0.00%+537+16.5%Added
Intrust Bank NA3,764$457.1K0.04%+889+30.9%Added
Leonteq Securities AG3,737$453.9K0.02%−48−1.3%Reduced
Public Employees Retirement Association of Colorado3,704$450.0K0.00%00.0%Unchanged
Forbes J M & Co LLP3,704$449.9K0.04%00.0%Unchanged
Old North State Wealth Management, LLC3,450$419.0K0.20%00.0%Unchanged
Mackenzie Financial Corp3,382$410.7K0.00%+1,097+48.0%Added
Ameritas Investment Partners, Inc.3,381$410.6K0.01%−751−18.2%Reduced
Point72 Hong Kong Ltd3,203$389.0K0.02%+3,203New
Xponance, Inc.3,189$387.3K0.00%+35+1.1%Added
Profund Advisors LLC3,122$379.2K0.01%−941−23.2%Reduced
Quantinno Capital Management LP2,842$345.2K0.00%+668+30.7%Added
SRS Capital Advisors, Inc.2,707$328.8K0.00%+2,640+3,940.3%Added
Fiduciary Family Office, LLC2,670$324.3K0.09%+2,670New
NBC Securities, Inc.2,670$324.3K0.02%+60+2.3%Added
Graham Capital Management, L.P.2,607$316.6K0.01%−1,777−40.5%Reduced
Headlands Technologies LLC2,574$312.6K0.02%+2,476+2,526.5%Added
Freestone Grove Partners LP2,494$302.9K0.00%+2,494New
National Asset Management, Inc.2,473$300.3K0.01%+2+0.1%Added
Moors & Cabot, Inc.2,380$289.1K0.01%+50+2.1%Added
Lombard Odier Asset Management (USA) Corp2,379$288.9K0.07%−27−1.1%Reduced
O'Shaughnessy Asset Management, LLC2,330$283.0K0.00%+2,330New
HRT Financial LP2,281$277.0K0.00%+2,281New
EntryPoint Capital, LLC2,263$274.8K0.11%+176+8.4%Added
McAdam, LLC2,198$266.9K0.01%+2+0.1%Added
Brinker Capital Investments, LLC2,189$265.9K0.00%+53+2.5%Added
Invst, LLC2,140$259.9K0.03%+26+1.2%Added
Tortoise Investment Management, LLC2,136$259.4K0.02%00.0%Unchanged
Adams Wealth Management2,169$259.0K0.06%00.0%Unchanged
CacheTech Inc.2,169$259.0K0.05%00.0%Unchanged
JustInvest LLC2,101$255.2K0.00%+134+6.8%Added
Quantitative Investment Management, LLC2,095$254.0K0.04%+2,095New
Baader Bank INC2,115$251.5K0.02%+2,115New
Verition Fund Management LLC1,989$241.6K0.00%+1,989New
Mercer Global Advisors Inc1,962$238.3K0.00%+1,962New
Vident Advisory, LLC1,957$237.7K0.00%+1,957New
Truist Financial Corp1,955$237.4K0.00%+1,955New
Mirae Asset Global Investments Co., Ltd.1,929$234.3K0.00%+27+1.4%Added
Davenport & Co LLC1,867$226.7K0.00%+1,867New
M&T Bank Corp1,864$226.0K0.00%+1,864New
The PNC Financial Services Group, Inc.1,856$225.4K0.00%+107+6.1%Added
XTX Topco Ltd1,839$223.3K0.01%+1,839New
Signature Estate & Investment Advisors LLC1,832$222.5K0.00%+1,832New
Atria Investments LLC1,769$214.8K0.00%+1,769New
Bank Hapoalim BM1,750$213.0K0.03%+1,750New
Rafferty Asset Management, LLC1,742$211.6K0.00%−457−20.8%Reduced
WealthPlan Investment Management, LLC1,693$205.6K0.01%+1,693New
Allworth Financial LP1,442$175.1K0.00%+89+6.6%Added
Bessemer Group Inc1,415$172.0K0.00%+1,280+948.1%Added
Clearstead Advisors, LLC1,328$161.3K0.00%+136+11.4%Added
Amalgamated Bank1,269$154.0K0.00%00.0%Unchanged
Assetmark, Inc1,253$152.2K0.00%+129+11.5%Added
Quarry LP1,250$151.8K0.04%−1,250−50.0%Reduced
Financial Consulate, Inc1,217$147.8K0.02%+1,217New
KBC Group NV1,121$136.0K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC1,082$131.4K0.00%+55+5.4%Added
GF Fund Management Co. Ltd.1,074$130.4K0.00%−167−13.5%Reduced
Bayforest Capital Ltd1,062$129.0K0.06%+1,062New
Sectoral Asset Management Inc1,020$123.9K0.08%00.0%Unchanged
Tower Research Capital LLC (TRC)762$92.5K0.00%−3,118−80.4%Reduced
Ameritas Advisory Services, LLC735$89.3K0.01%00.0%Unchanged
Point72 (DIFC) Ltd564$68.5K0.00%+564New
Quest Partners LLC554$67.3K0.00%−1,054−65.5%Reduced
Johnson Financial Group, Inc.503$61.1K0.00%+503New
Covestor Ltd501$61.0K0.03%+374+294.5%Added
Walleye Capital LLC500$60.7K0.00%−1,783−78.1%Reduced
Abich Financial Wealth Management LLC496$60.2K0.02%+496New
Natixis485$58.9K0.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co472$57.3K0.00%+66+16.3%Added
Key Financial Inc450$53.4K0.01%00.0%Unchanged
Armstrong Advisory Group, Inc423$51.4K0.00%00.0%Unchanged
Trust Co of Vermont400$48.6K0.00%00.0%Unchanged
Umb Bank N A371$45.1K0.00%+253+214.4%Added