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Axsome Therapeutics, Inc.

AXSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001579428

In the last 90 days, Axsome Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 505 institutions reported holding it in 13F filings for Q2 2026, worth $9.34B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Axsome Therapeutics, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
292
+21 vs. Q3 2024
Shares held
37.2M
−1.12M (−2.9%) vs. Q3 2024
Total value
$3.15B
−$295.5M (−8.6%) vs. Q3 2024
New holders
61
91 more added
Sold out
40
90 more reduced

9 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AXSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 292 institutions
Q1 2021: 184 institutionsQ2 2021: 176 institutionsQ3 2021: 171 institutionsQ4 2021: 167 institutionsQ1 2022: 175 institutionsQ2 2022: 174 institutionsQ3 2022: 188 institutionsQ4 2022: 219 institutionsQ1 2023: 197 institutionsQ2 2023: 231 institutionsQ3 2023: 227 institutionsQ4 2023: 245 institutionsQ1 2024: 259 institutionsQ2 2024: 257 institutionsQ3 2024: 280 institutionsQ4 2024: 292 institutionsQ1 2025: 353 institutionsQ2 2025: 348 institutionsQ3 2025: 355 institutionsQ4 2025: 399 institutionsQ1 2026: 410 institutionsQ2 2026: 505 institutions
Value heldQ4 2024: $3.15B
Q1 2021: $1.31BQ2 2021: $1.51BQ3 2021: $627.3MQ4 2021: $704.2MQ1 2022: $787.4MQ2 2022: $826.7MQ3 2022: $1.15BQ4 2022: $2.32BQ1 2023: $1.97BQ2 2023: $2.61BQ3 2023: $2.65BQ4 2023: $3.07BQ1 2024: $3.09BQ2 2024: $3.28BQ3 2024: $3.48BQ4 2024: $3.15BQ1 2025: $4.37BQ2 2025: $3.95BQ3 2025: $4.51BQ4 2025: $6.86BQ1 2026: $6.41BQ2 2026: $9.34B
Institutions holding AXSM and their total value by quarter
QuarterHoldersValue
Q2 2026505$9.34B
Q1 2026410$6.41B
Q4 2025399$6.86B
Q3 2025355$4.51B
Q2 2025348$3.95B
Q1 2025353$4.37B
Q4 2024292$3.15B
Q3 2024280$3.48B
Q2 2024257$3.28B
Q1 2024259$3.09B
Q4 2023245$3.07B
Q3 2023227$2.65B
Q2 2023231$2.61B
Q1 2023197$1.97B
Q4 2022219$2.32B
Q3 2022188$1.15B
Q2 2022174$826.7M
Q1 2022175$787.4M
Q4 2021167$704.2M
Q3 2021171$627.3M
Q2 2021176$1.51B
Q1 2021184$1.31B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Axsome Therapeutics, Inc.; share changes are against Q3 2024.

Institutions holding AXSM in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
RTW Investments, LP4,051,365$342.8M5.18%−138,192−3.3%Reduced
Vanguard Group Inc3,902,479$330.2M0.01%−92,866−2.3%Reduced
BlackRock, Inc.3,533,394$299.0M0.01%+135,015+4.0%Added
Fairmount Funds Management LLC1,468,983$124.3M12.36%−891,094−37.8%Reduced
BVF Inc1,388,064$117.4M3.98%+342,064+32.7%Added
FMR LLC1,000,446$84.6M0.01%−87,641−8.1%Reduced
Ra Capital Management, L.P.1,000,000$84.6M1.13%00.0%Unchanged
Macquarie Group Ltd964,047$81.6M0.10%−31,240−3.1%Reduced
State Street Corp947,251$80.1M0.00%+30,443+3.3%Added
Geode Capital Management, LLC912,538$77.2M0.01%+4,079+0.4%Added
Eventide Asset Management, LLC828,711$70.1M1.28%+824+0.1%Added
Alethea Capital Management, LLC734,317$62.1M53.19%−4,186−0.6%Reduced
Invesco Ltd.692,464$58.6M0.01%+67,285+10.8%Added
Wellington Management Group LLP673,157$57.0M0.01%−69,588−9.4%Reduced
Perceptive Advisors LLC664,074$56.2M1.57%−118,770−15.2%Reduced
Hood River Capital Management LLC644,785$54.6M0.81%+19,701+3.2%Added
Morgan Stanley576,858$48.8M0.00%+166,708+40.6%Added
Lazard Asset Management LLC537,669$45.5M0.07%+451,737+525.7%Added
Citadel Advisors LLC495,389$41.9M0.04%+190,707+62.6%Added
Sofinnova Investments, Inc.491,726$41.6M3.05%+112,199+29.6%Added
Boxer Capital Management, LLC470,000$39.8M3.39%+470,000New
PFM Health Sciences, LP467,427$39.5M3.01%00.0%Unchanged
Woodline Partners LP408,441$34.6M0.23%+109,872+36.8%Added
Norges Bank403,026$34.1M0.00%+11,710+3.0%Added
Northern Trust Corp402,500$34.1M0.00%+69,918+21.0%Added
Charles Schwab Investment Management Inc328,034$27.8M0.01%+5,438+1.7%Added
Cormorant Asset Management, LP325,000$27.5M1.51%−75,000−18.8%Reduced
Loomis Sayles & Co L P290,111$24.5M0.03%−8,475−2.8%Reduced
Tri Locum Partners LP249,769$21.1M4.38%+158,048+172.3%Added
Nuveen Asset Management, LLC221,202$18.7M0.01%+119,780+118.1%Added
Goldman Sachs Group Inc217,567$18.4M0.00%−145,058−40.0%Reduced
Principal Financial Group Inc207,065$17.5M0.01%+203,672+6,002.7%Added
Bank of America Corp204,587$17.3M0.00%−522,941−71.9%Reduced
JPMorgan Chase & Co201,902$17.1M0.00%−10,208−4.8%Reduced
First Turn Management, LLC192,146$16.3M2.91%−63,148−24.7%Reduced
Avidity Partners Management LP188,000$15.9M1.59%−108,100−36.5%Reduced
BNP Paribas Arbitrage, SA185,661$15.7M0.01%+171,928+1,251.9%Added
Point72 Asset Management, L.P.185,138$15.7M0.04%−357,482−65.9%Reduced
Franklin Resources Inc182,290$15.4M0.00%+21,756+13.6%Added
Balyasny Asset Management LLC181,213$15.3M0.04%+119,046+191.5%Added
Checkpoint Capital L.P.174,769$14.8M7.53%−34,863−16.6%Reduced
Raymond James Financial Inc174,586$14.8M0.01%+174,586New
Man Group plc163,388$13.8M0.04%+163,388New
Qube Research & Technologies Ltd155,911$13.2M0.02%+125,541+413.4%Added
UBS Group AG147,347$12.5M0.00%+99,585+208.5%Added
HSBC Holdings PLC136,785$11.6M0.01%−279−0.2%Reduced
Bank of New York Mellon Corp134,550$11.4M0.00%−1,896−1.4%Reduced
US Bancorp131,019$11.1M0.01%−2,107−1.6%Reduced
Marshall Wace, LLP127,097$10.8M0.01%+127,097New
Iridian Asset Management LLC125,079$10.6M2.82%−1,724−1.4%Reduced
Rhenman & Partners Asset Management AB122,600$10.4M1.07%00.0%Unchanged
Deutsche Bank AG120,547$10.2M0.00%+32,789+37.4%Added
Bellevue Group AG118,930$10.1M0.19%−248,251−67.6%Reduced
Cubist Systematic Strategies, LLC116,937$9.89M0.16%+116,937New
Caption Management, LLC115,686$9.79M0.40%+105,686+1,056.9%Added
Clearbridge Investments, LLC113,077$9.57M0.01%−1,159−1.0%Reduced
WCM Investment Management, LLC111,996$9.50M0.02%−1,696−1.5%Reduced
Voya Investment Management LLC102,742$8.69M0.01%+8,259+8.7%Added
Barclays PLC97,988$8.29M0.00%+36,203+58.6%Added
Granite Investment Partners, LLC91,649$7.75M0.34%+91,649New
Squarepoint Ops LLC89,430$7.57M0.02%+89,430New
Peregrine Capital Management LLC87,187$7.38M0.22%+15,258+21.2%Added
Spears Abacus Advisors LLC82,087$6.95M0.14%00.0%Unchanged
Jane Street Group, LLC78,449$6.64M0.01%−51,648−39.7%Reduced
Affinity Asset Advisors, LLC75,000$6.35M0.99%−5,000−6.3%Reduced
DnB Asset Management AS73,770$6.24M0.03%+67,626+1,100.7%Added
Connor, Clark & Lunn Investment Management Ltd.73,497$6.22M0.03%+73,497New
Standard Life Aberdeen plc72,179$6.11M0.01%+61,131+553.3%Added
IFP Advisors, Inc67,839$5.74M0.19%+18,038+36.2%Added
Ally Bridge Group (NY) LLC66,661$5.64M4.84%+66,661New
Privium Fund Management B.V.62,232$5.27M1.19%−18,000−22.4%Reduced
Lindbrook Capital, LLC62,144$5.26M0.47%−2,563−4.0%Reduced
Swiss National Bank61,400$5.20M0.00%+900+1.5%Added
Adage Capital Partners GP, L.L.C.60,000$5.08M0.01%−465,000−88.6%Reduced
Hennion & Walsh Asset Management, Inc.57,836$4.89M0.22%−312−0.5%Reduced
UBS Asset Management Americas Inc57,642$4.88M0.00%+9,928+20.8%Added
First Trust Advisors LP54,580$4.62M0.00%+11,488+26.7%Added
Blair William & Co54,382$4.60M0.01%−788−1.4%Reduced
Frontier Capital Management Co LLC52,768$4.46M0.04%−67,772−56.2%Reduced
Rhumbline Advisers51,245$4.34M0.00%−148−0.3%Reduced
MPM Oncology Impact Management LP50,000$4.23M0.60%+50,000New
Baldwin Brothers Inc49,570$4.19M0.29%−125−0.3%Reduced
SEI Investments Co48,230$4.08M0.01%−131−0.3%Reduced
Alliancebernstein L.P.46,590$3.94M0.00%−78,388−62.7%Reduced
Moody Aldrich Partners LLC45,138$3.82M0.71%−15,506−25.6%Reduced
Group One Trading, L.P.43,820$3.71M0.13%−6,321−12.6%Reduced
Citigroup Inc42,961$3.63M0.00%+7,342+20.6%Added
Point72 Europe (London) LLP41,734$3.53M0.20%+7,164+20.7%Added
Polygon Management Ltd.41,250$3.49M1.13%+41,250New
Jefferies Financial Group Inc.40,700$3.44M0.04%+40,700New
J. Goldman & Co LP40,323$3.41M0.12%+32,044+387.1%Added
Wells Fargo & Company39,736$3.36M0.00%−221−0.6%Reduced
Mutual of America Capital Management LLC39,487$3.34M0.04%−35−0.1%Reduced
Alps Advisors Inc39,190$3.32M0.02%+39,190New
Brevan Howard Capital Management LP38,748$3.28M0.08%+24,393+169.9%Added
AQR Capital Management LLC38,211$3.23M0.00%+11,049+40.7%Added
Kennedy Capital Management, Inc.37,941$3.21M0.07%+18,510+95.3%Added
Royce & Associates LP37,000$3.13M0.03%+14,500+64.4%Added
Legal & General Group Plc36,370$3.08M0.00%+2,107+6.1%Added
Envestnet Asset Management Inc35,129$2.97M0.00%+15,047+74.9%Added