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Axsome Therapeutics, Inc.

AXSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001579428

In the last 90 days, Axsome Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 505 institutions reported holding it in 13F filings for Q2 2026, worth $9.34B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Axsome Therapeutics, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
348
−2 vs. Q1 2025
Shares held
37.9M
+462.6K (+1.2%) vs. Q1 2025
Total value
$3.95B
−$409.9M (−9.4%) vs. Q1 2025
New holders
55
154 more added
Sold out
57
90 more reduced

3 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AXSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 348 institutions
Q1 2021: 184 institutionsQ2 2021: 176 institutionsQ3 2021: 171 institutionsQ4 2021: 167 institutionsQ1 2022: 175 institutionsQ2 2022: 174 institutionsQ3 2022: 188 institutionsQ4 2022: 219 institutionsQ1 2023: 197 institutionsQ2 2023: 231 institutionsQ3 2023: 227 institutionsQ4 2023: 245 institutionsQ1 2024: 259 institutionsQ2 2024: 257 institutionsQ3 2024: 280 institutionsQ4 2024: 292 institutionsQ1 2025: 353 institutionsQ2 2025: 348 institutionsQ3 2025: 355 institutionsQ4 2025: 399 institutionsQ1 2026: 410 institutionsQ2 2026: 505 institutions
Value heldQ2 2025: $3.95B
Q1 2021: $1.31BQ2 2021: $1.51BQ3 2021: $627.3MQ4 2021: $704.2MQ1 2022: $787.4MQ2 2022: $826.7MQ3 2022: $1.15BQ4 2022: $2.32BQ1 2023: $1.97BQ2 2023: $2.61BQ3 2023: $2.65BQ4 2023: $3.07BQ1 2024: $3.09BQ2 2024: $3.28BQ3 2024: $3.48BQ4 2024: $3.15BQ1 2025: $4.37BQ2 2025: $3.95BQ3 2025: $4.51BQ4 2025: $6.86BQ1 2026: $6.41BQ2 2026: $9.34B
Institutions holding AXSM and their total value by quarter
QuarterHoldersValue
Q2 2026505$9.34B
Q1 2026410$6.41B
Q4 2025399$6.86B
Q3 2025355$4.51B
Q2 2025348$3.95B
Q1 2025353$4.37B
Q4 2024292$3.15B
Q3 2024280$3.48B
Q2 2024257$3.28B
Q1 2024259$3.09B
Q4 2023245$3.07B
Q3 2023227$2.65B
Q2 2023231$2.61B
Q1 2023197$1.97B
Q4 2022219$2.32B
Q3 2022188$1.15B
Q2 2022174$826.7M
Q1 2022175$787.4M
Q4 2021167$704.2M
Q3 2021171$627.3M
Q2 2021176$1.51B
Q1 2021184$1.31B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Axsome Therapeutics, Inc.; share changes are against Q1 2025.

Institutions holding AXSM in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Vanguard Group Inc3,945,020$411.8M0.01%+68,078+1.8%Added
BlackRock, Inc.3,834,990$400.3M0.01%+310,579+8.8%Added
BVF Inc1,690,221$176.4M6.30%00.0%Unchanged
RTW Investments, LP1,516,903$158.3M2.26%−1,405,826−48.1%Reduced
Macquarie Group Ltd1,137,748$118.8M0.15%+161,488+16.5%Added
Geode Capital Management, LLC989,453$103.3M0.01%+54,600+5.8%Added
FMR LLC976,730$102.0M0.01%−270,501−21.7%Reduced
State Street Corp958,503$100.1M0.00%+52,483+5.8%Added
Fairmount Funds Management LLC815,176$85.1M11.02%00.0%Unchanged
Deep Track Capital, LP801,371$83.7M2.69%+801,371New
Bank of America Corp753,429$78.7M0.01%+219,527+41.1%Added
Eventide Asset Management, LLC725,672$75.7M1.33%−19,178−2.6%Reduced
Wellington Management Group LLP725,044$75.7M0.01%+21,765+3.1%Added
Alethea Capital Management, LLC667,368$69.7M52.72%00.0%Unchanged
Price T Rowe Associates Inc612,743$64.0M0.01%+580,766+1,816.2%Added
UBS Group AG595,455$62.2M0.01%+306,808+106.3%Added
Invesco Ltd.571,549$59.7M0.01%−285,452−33.3%Reduced
Man Group plc525,069$54.8M0.12%+11,848+2.3%Added
PFM Health Sciences, LP483,105$50.4M4.37%−73,440−13.2%Reduced
Norges Bank468,329$48.9M0.01%+30,832+7.0%Added
Morgan Stanley447,919$46.8M0.00%−9,497−2.1%Reduced
Adage Capital Partners GP, L.L.C.447,000$46.7M0.08%+399,000+831.3%Added
OrbiMed Advisors LLC427,900$44.7M1.12%+41,200+10.7%Added
Pictet Asset Management Holding SA411,850$43.0M0.04%+78,645+23.6%Added
Northern Trust Corp409,394$42.7M0.01%−1,575−0.4%Reduced
Qube Research & Technologies Ltd391,617$40.9M0.06%+109,241+38.7%Added
Hood River Capital Management LLC371,104$38.7M0.54%+371,104New
Charles Schwab Investment Management Inc356,651$37.2M0.01%+19,405+5.8%Added
Principal Financial Group Inc355,511$37.1M0.02%+59,840+20.2%Added
Point72 Asset Management, L.P.350,973$36.6M0.09%+224,780+178.1%Added
Woodline Partners LP331,131$34.6M0.18%+27,047+8.9%Added
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.326,318$34.1M4.03%+40,824+14.3%Added
Nuveen, LLC282,971$29.5M0.01%−130,170−31.5%Reduced
Franklin Resources Inc278,510$29.1M0.01%+51,995+23.0%Added
Loomis Sayles & Co L P277,465$29.0M0.04%−6,705−2.4%Reduced
T. Rowe Price Investment Management, Inc.248,726$26.0M0.02%−18,271−6.8%Reduced
Goldman Sachs Group Inc228,204$23.8M0.00%−73,514−24.4%Reduced
Connor, Clark & Lunn Investment Management Ltd.224,721$23.5M0.08%+48,779+27.7%Added
Driehaus Capital Management LLC223,280$23.3M0.19%+9,141+4.3%Added
Bank of New York Mellon Corp203,632$21.3M0.00%+72,609+55.4%Added
D. E. Shaw & Co., Inc.200,764$21.0M0.02%−346,901−63.3%Reduced
Perceptive Advisors LLC198,534$20.7M0.78%−156,573−44.1%Reduced
JPMorgan Chase & Co187,728$19.6M0.00%+62,945+50.4%Added
BNP Paribas Arbitrage, SA186,437$19.5M0.02%+3,805+2.1%Added
MetLife Investment Management184,164$19.2M0.11%+5,209+2.9%Added
Assenagon Asset Management S.A.180,960$18.9M0.03%−446,458−71.2%Reduced
Squarepoint Ops LLC163,000$17.0M0.04%+21,403+15.1%Added
Raymond James Financial Inc161,412$16.8M0.01%+6,337+4.1%Added
Cubist Systematic Strategies, LLC159,233$16.6M0.18%−18,581−10.4%Reduced
Tri Locum Partners LP157,861$16.5M5.00%+56,621+55.9%Added
First Turn Management, LLC144,400$15.1M2.81%+26,221+22.2%Added
Blackstone Group Inc.140,000$14.6M0.07%+140,000New
Voya Investment Management LLC139,289$14.5M0.01%+40,289+40.7%Added
Renaissance Technologies LLC138,700$14.5M0.02%+4,300+3.2%Added
UBS Asset Management Americas Inc134,101$14.0M0.00%+59,209+79.1%Added
Manufacturers Life Insurance Company, The133,823$14.0M0.01%+110,972+485.6%Added
US Bancorp130,847$13.7M0.02%+552+0.4%Added
Granite Investment Partners, LLC128,526$13.4M0.65%−10,193−7.3%Reduced
Jump Financial, LLC128,500$13.4M0.16%+35,860+38.7%Added
AQR Capital Management LLC127,817$13.3M0.01%+69,454+119.0%Added
WCM Investment Management, LLC119,666$12.4M0.03%+7,718+6.9%Added
Emerald Advisers, LLC112,469$11.7M0.43%+112,469New
Bridgewater Associates, LP107,292$11.2M0.05%+64,467+150.5%Added
Susquehanna International Group, LLP106,021$11.1M0.02%+54,295+105.0%Added
Cormorant Asset Management, LP100,000$10.4M0.78%−150,000−60.0%Reduced
HSBC Holdings PLC98,118$10.2M0.01%+14,546+17.4%Added
Barclays PLC97,490$10.2M0.00%+45,620+88.0%Added
Readystate Asset Management LP94,571$9.87M0.41%+35,018+58.8%Added
Avidity Partners Management LP94,500$9.86M1.98%+17,500+22.7%Added
Sofinnova Investments, Inc.93,610$9.77M0.66%−81,707−46.6%Reduced
Deutsche Bank AG92,890$9.70M0.00%−2,090−2.2%Reduced
Iridian Asset Management LLC91,761$9.58M3.32%−14,551−13.7%Reduced
Rhenman & Partners Asset Management AB90,800$9.48M1.20%−18,800−17.2%Reduced
Citigroup Inc85,011$8.87M0.01%+45,842+117.0%Added
Spears Abacus Advisors LLC84,151$8.78M0.18%−113−0.1%Reduced
Standard Life Aberdeen plc81,916$8.55M0.01%+17,962+28.1%Added
Candriam Luxembourg S.C.A.76,727$8.01M0.05%−3,203−4.0%Reduced
DnB Asset Management AS76,642$8.00M0.03%+15,114+24.6%Added
Peregrine Capital Management LLC73,468$7.67M0.23%+13,747+23.0%Added
Canada Pension Plan Investment Board72,300$7.55M0.01%+27,800+62.5%Added
Neuberger Berman Group LLC70,632$7.37M0.01%+70,632New
Ameriprise Financial Inc70,084$7.32M0.00%+54,068+337.6%Added
Edgestream Partners, L.P.69,961$7.30M0.20%−125−0.2%Reduced
Swiss National Bank65,200$6.81M0.00%+4,200+6.9%Added
IFP Advisors, Inc64,018$6.68M0.19%−4,096−6.0%Reduced
Emerald Mutual Fund Advisers Trust63,935$6.67M0.41%+63,935New
First Trust Advisors LP62,160$6.49M0.01%+33,209+114.7%Added
Rhumbline Advisers61,807$6.45M0.01%+7,047+12.9%Added
Moody Aldrich Partners LLC61,410$6.41M1.24%−929−1.5%Reduced
Capital Fund Management S.A.60,763$6.34M0.07%+47,738+366.5%Added
Marshall Wace, LLP56,716$5.92M0.01%−11,980−17.4%Reduced
Federated Hermes, Inc.56,469$5.89M0.01%+30,479+117.3%Added
Clearbridge Investments, LLC56,316$5.88M0.00%−11,848−17.4%Reduced
Bellevue Group AG56,253$5.87M0.13%−40,154−41.7%Reduced
Wells Fargo & Company55,703$5.81M0.00%+14,088+33.9%Added
Privium Fund Management B.V.52,732$5.43M1.17%00.0%Unchanged
Universal- Beteiligungs- und Servicegesellschaft mbH51,968$5.42M0.01%+1,872+3.7%Added
Affinity Asset Advisors, LLC50,000$5.22M0.77%−50,000−50.0%Reduced
Hennion & Walsh Asset Management, Inc.49,900$5.21M0.21%−9,373−15.8%Reduced
Blair William & Co49,482$5.17M0.01%−3,047−5.8%Reduced