Axsome Therapeutics, Inc.
AXSM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001579428
In the last 90 days, Axsome Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 505 institutions reported holding it in 13F filings for Q2 2026, worth $9.34B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Axsome Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 355
- +10 vs. Q2 2025
- Shares held
- 37.2M
- −189.7K (−0.5%) vs. Q2 2025
- Total value
- $4.51B
- +$613.1M (+15.7%) vs. Q2 2025
- New holders
- 49
- 146 more added
- Sold out
- 39
- 104 more reduced
3 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AXSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 505 | $9.34B |
| Q1 2026 | 410 | $6.41B |
| Q4 2025 | 399 | $6.86B |
| Q3 2025 | 355 | $4.51B |
| Q2 2025 | 348 | $3.95B |
| Q1 2025 | 353 | $4.37B |
| Q4 2024 | 292 | $3.15B |
| Q3 2024 | 280 | $3.48B |
| Q2 2024 | 257 | $3.28B |
| Q1 2024 | 259 | $3.09B |
| Q4 2023 | 245 | $3.07B |
| Q3 2023 | 227 | $2.65B |
| Q2 2023 | 231 | $2.61B |
| Q1 2023 | 197 | $1.97B |
| Q4 2022 | 219 | $2.32B |
| Q3 2022 | 188 | $1.15B |
| Q2 2022 | 174 | $826.7M |
| Q1 2022 | 175 | $787.4M |
| Q4 2021 | 167 | $704.2M |
| Q3 2021 | 171 | $627.3M |
| Q2 2021 | 176 | $1.51B |
| Q1 2021 | 184 | $1.31B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Axsome Therapeutics, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vanguard Group Inc | 4,180,646 | $507.7M | 0.01% | +235,626+6.0% | Added |
| BlackRock, Inc. | 3,790,929 | $460.4M | 0.01% | −44,061−1.1% | Reduced |
| Wellington Management Group LLP | 1,334,560 | $162.1M | 0.03% | +609,516+84.1% | Added |
| RTW Investments, LP | 1,118,883 | $135.9M | 1.67% | −398,020−26.2% | Reduced |
| Macquarie Group Ltd | 1,084,536 | $131.7M | 0.15% | −53,212−4.7% | Reduced |
| Price T Rowe Associates Inc | 1,037,448 | $126.0M | 0.01% | +424,705+69.3% | Added |
| Geode Capital Management, LLC | 997,700 | $121.2M | 0.01% | +8,247+0.8% | Added |
| Invesco Ltd. | 990,557 | $120.3M | 0.02% | +419,008+73.3% | Added |
| State Street Corp | 942,960 | $114.5M | 0.00% | −15,543−1.6% | Reduced |
| FMR LLC | 927,883 | $112.7M | 0.01% | −48,847−5.0% | Reduced |
| Deep Track Capital, LP | 900,000 | $109.3M | 3.05% | +98,629+12.3% | Added |
| Fairmount Funds Management LLC | 815,176 | $99.0M | 8.91% | 00.0% | Unchanged |
| Eventide Asset Management, LLC | 746,398 | $90.6M | 1.49% | +20,726+2.9% | Added |
| Alethea Capital Management, LLC | 670,883 | $81.5M | 52.44% | +3,515+0.5% | Added |
| OrbiMed Advisors LLC | 531,800 | $64.6M | 1.55% | +103,900+24.3% | Added |
| PFM Health Sciences, LP | 530,332 | $64.4M | 5.49% | +47,227+9.8% | Added |
| BVF Inc | 486,757 | $59.1M | 2.40% | −1,203,464−71.2% | Reduced |
| Adage Capital Partners GP, L.L.C. | 445,000 | $54.0M | 0.09% | −2,000−0.4% | Reduced |
| Morgan Stanley | 409,580 | $49.7M | 0.00% | −38,339−8.6% | Reduced |
| Northern Trust Corp | 409,535 | $49.7M | 0.01% | +1410.0% | Added |
| Sofinnova Investments, Inc. | 393,499 | $47.8M | 2.93% | +299,889+320.4% | Added |
| Charles Schwab Investment Management Inc | 382,047 | $46.4M | 0.01% | +25,396+7.1% | Added |
| Marshall Wace, LLP | 378,024 | $45.9M | 0.05% | +321,308+566.5% | Added |
| Principal Financial Group Inc | 368,434 | $44.7M | 0.02% | +12,923+3.6% | Added |
| Pictet Asset Management Holding SA | 362,138 | $44.0M | 0.04% | −49,712−12.1% | Reduced |
| Bank of America Corp | 361,261 | $43.9M | 0.00% | −392,168−52.1% | Reduced |
| Hood River Capital Management LLC | 359,957 | $43.7M | 0.52% | −11,147−3.0% | Reduced |
| Woodline Partners LP | 331,864 | $40.3M | 0.19% | +733+0.2% | Added |
| Loomis Sayles & Co L P | 330,125 | $40.1M | 0.05% | +52,660+19.0% | Added |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 326,318 | $39.6M | 3.06% | 00.0% | Unchanged |
| Qube Research & Technologies Ltd | 325,626 | $39.5M | 0.06% | −65,991−16.9% | Reduced |
| Nuveen, LLC | 298,341 | $36.2M | 0.01% | +15,370+5.4% | Added |
| D. E. Shaw & Co., Inc. | 296,287 | $36.0M | 0.03% | +95,523+47.6% | Added |
| Assenagon Asset Management S.A. | 294,771 | $35.8M | 0.05% | +113,811+62.9% | Added |
| Tri Locum Partners LP | 292,137 | $35.5M | 8.16% | +134,276+85.1% | Added |
| Man Group plc | 287,908 | $35.0M | 0.07% | −237,161−45.2% | Reduced |
| Franklin Resources Inc | 285,598 | $34.7M | 0.01% | +7,088+2.5% | Added |
| T. Rowe Price Investment Management, Inc. | 274,014 | $33.3M | 0.02% | +25,288+10.2% | Added |
| Bank of New York Mellon Corp | 253,263 | $30.8M | 0.01% | +49,631+24.4% | Added |
| JPMorgan Chase & Co | 250,513 | $30.4M | 0.00% | +62,785+33.4% | Added |
| Goldman Sachs Group Inc | 224,139 | $27.2M | 0.00% | −4,065−1.8% | Reduced |
| Driehaus Capital Management LLC | 223,408 | $27.1M | 0.19% | +128+0.1% | Added |
| UBS Group AG | 212,451 | $25.8M | 0.01% | −383,004−64.3% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 209,069 | $25.4M | 0.08% | −15,652−7.0% | Reduced |
| MetLife Investment Management | 197,318 | $24.0M | 0.12% | +13,154+7.1% | Added |
| BNP Paribas Arbitrage, SA | 190,106 | $23.1M | 0.02% | +3,669+2.0% | Added |
| Rhenman & Partners Asset Management AB | 172,800 | $21.0M | 2.32% | +82,000+90.3% | Added |
| Raymond James Financial Inc | 158,689 | $19.3M | 0.01% | −2,723−1.7% | Reduced |
| Citadel Advisors LLC | 158,406 | $19.2M | 0.02% | +144,788+1,063.2% | Added |
| Squarepoint Ops LLC | 155,000 | $18.8M | 0.04% | −8,000−4.9% | Reduced |
| First Turn Management, LLC | 152,614 | $18.5M | 2.78% | +8,214+5.7% | Added |
| Renaissance Technologies LLC | 150,000 | $18.2M | 0.02% | +11,300+8.1% | Added |
| Vestal Point Capital, LP | 150,000 | $18.2M | 0.83% | +150,000 | New |
| Perceptive Advisors LLC | 148,900 | $18.1M | 0.52% | −49,634−25.0% | Reduced |
| Citigroup Inc | 142,013 | $17.2M | 0.01% | +57,002+67.1% | Added |
| Blackstone Group Inc. | 140,000 | $17.0M | 0.07% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 132,717 | $16.1M | 0.01% | −1,106−0.8% | Reduced |
| US Bancorp | 131,533 | $16.0M | 0.02% | +686+0.5% | Added |
| Jane Street Group, LLC | 130,845 | $15.9M | 0.02% | +130,845 | New |
| Frontier Capital Management Co LLC | 126,382 | $15.3M | 0.14% | +97,540+338.2% | Added |
| AQR Capital Management LLC | 118,656 | $14.4M | 0.01% | −9,161−7.2% | Reduced |
| WCM Investment Management, LLC | 119,696 | $14.1M | 0.03% | +300.0% | Added |
| Voya Investment Management LLC | 114,050 | $13.9M | 0.01% | −25,239−18.1% | Reduced |
| Emerald Advisers, LLC | 108,942 | $13.2M | 0.42% | −3,527−3.1% | Reduced |
| Ameriprise Financial Inc | 108,236 | $13.1M | 0.00% | +38,152+54.4% | Added |
| DnB Asset Management AS | 101,981 | $12.4M | 0.05% | +25,339+33.1% | Added |
| HSBC Holdings PLC | 101,001 | $12.3M | 0.01% | +2,883+2.9% | Added |
| Cormorant Asset Management, LP | 100,000 | $12.1M | 0.84% | 00.0% | Unchanged |
| Deutsche Bank AG | 96,692 | $11.7M | 0.00% | +3,802+4.1% | Added |
| Standard Life Aberdeen plc | 94,648 | $11.5M | 0.02% | +12,732+15.5% | Added |
| Neuberger Berman Group LLC | 91,178 | $11.1M | 0.01% | +20,546+29.1% | Added |
| Granite Investment Partners, LLC | 88,558 | $10.8M | 0.61% | −39,968−31.1% | Reduced |
| UBS Asset Management Americas Inc | 86,691 | $10.5M | 0.00% | −47,410−35.4% | Reduced |
| Spears Abacus Advisors LLC | 84,151 | $10.2M | 0.19% | 00.0% | Unchanged |
| Iridian Asset Management LLC | 83,553 | $10.1M | 3.99% | −8,208−8.9% | Reduced |
| Summit Financial, LLC | 77,540 | $9.42M | 0.14% | +77,540 | New |
| Barclays PLC | 72,067 | $8.75M | 0.00% | −25,423−26.1% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 67,902 | $8.25M | 0.01% | +15,934+30.7% | Added |
| Swiss National Bank | 66,800 | $8.11M | 0.00% | +1,600+2.5% | Added |
| Emerald Mutual Fund Advisers Trust | 65,505 | $7.96M | 0.41% | +1,570+2.5% | Added |
| Peregrine Capital Management LLC | 64,521 | $7.84M | 0.24% | −8,947−12.2% | Reduced |
| Canada Pension Plan Investment Board | 64,400 | $7.82M | 0.01% | −7,900−10.9% | Reduced |
| IFP Advisors, Inc | 63,313 | $7.69M | 0.20% | −705−1.1% | Reduced |
| Alliancebernstein L.P. | 63,065 | $7.66M | 0.00% | +17,083+37.2% | Added |
| Rhumbline Advisers | 60,778 | $7.38M | 0.01% | −1,029−1.7% | Reduced |
| Clearbridge Investments, LLC | 57,667 | $7.00M | 0.01% | +1,351+2.4% | Added |
| Federated Hermes, Inc. | 57,285 | $6.96M | 0.01% | +816+1.4% | Added |
| HighTower Advisors, LLC | 57,115 | $6.94M | 0.01% | +46,153+421.0% | Added |
| Royce & Associates LP | 56,036 | $6.81M | 0.07% | +30,279+117.6% | Added |
| Wells Fargo & Company | 55,273 | $6.71M | 0.00% | −430−0.8% | Reduced |
| Privium Fund Management B.V. | 52,732 | $6.40M | 1.15% | 00.0% | Unchanged |
| Bellevue Group AG | 52,335 | $6.36M | 0.13% | −3,918−7.0% | Reduced |
| Moody Aldrich Partners LLC | 51,476 | $6.25M | 1.19% | −9,934−16.2% | Reduced |
| Susquehanna International Group, LLP | 50,246 | $6.10M | 0.01% | −55,775−52.6% | Reduced |
| Blair William & Co | 50,077 | $6.08M | 0.02% | +595+1.2% | Added |
| Axiom Investors LLC | 49,253 | $5.98M | 0.04% | +22,147+81.7% | Added |
| Atika Capital Management LLC | 49,000 | $5.95M | 0.51% | +2,879+6.2% | Added |
| Nicholas Investment Partners, LP | 48,657 | $5.91M | 0.45% | +6,503+15.4% | Added |
| Baldwin Brothers Inc | 48,570 | $5.90M | 0.38% | 00.0% | Unchanged |
| SEI Investments Co | 48,127 | $5.85M | 0.01% | +4,178+9.5% | Added |