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Axsome Therapeutics, Inc.

AXSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001579428

In the last 90 days, Axsome Therapeutics, Inc. insiders filed 0 open-market purchases and 2 sales; 505 institutions reported holding it in 13F filings for Q2 2026, worth $9.34B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Axsome Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
355
+10 vs. Q2 2025
Shares held
37.2M
−189.7K (−0.5%) vs. Q2 2025
Total value
$4.51B
+$613.1M (+15.7%) vs. Q2 2025
New holders
49
146 more added
Sold out
39
104 more reduced

3 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AXSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 355 institutions
Q1 2021: 184 institutionsQ2 2021: 176 institutionsQ3 2021: 171 institutionsQ4 2021: 167 institutionsQ1 2022: 175 institutionsQ2 2022: 174 institutionsQ3 2022: 188 institutionsQ4 2022: 219 institutionsQ1 2023: 197 institutionsQ2 2023: 231 institutionsQ3 2023: 227 institutionsQ4 2023: 245 institutionsQ1 2024: 259 institutionsQ2 2024: 257 institutionsQ3 2024: 280 institutionsQ4 2024: 292 institutionsQ1 2025: 353 institutionsQ2 2025: 348 institutionsQ3 2025: 355 institutionsQ4 2025: 399 institutionsQ1 2026: 410 institutionsQ2 2026: 505 institutions
Value heldQ3 2025: $4.51B
Q1 2021: $1.31BQ2 2021: $1.51BQ3 2021: $627.3MQ4 2021: $704.2MQ1 2022: $787.4MQ2 2022: $826.7MQ3 2022: $1.15BQ4 2022: $2.32BQ1 2023: $1.97BQ2 2023: $2.61BQ3 2023: $2.65BQ4 2023: $3.07BQ1 2024: $3.09BQ2 2024: $3.28BQ3 2024: $3.48BQ4 2024: $3.15BQ1 2025: $4.37BQ2 2025: $3.95BQ3 2025: $4.51BQ4 2025: $6.86BQ1 2026: $6.41BQ2 2026: $9.34B
Institutions holding AXSM and their total value by quarter
QuarterHoldersValue
Q2 2026505$9.34B
Q1 2026410$6.41B
Q4 2025399$6.86B
Q3 2025355$4.51B
Q2 2025348$3.95B
Q1 2025353$4.37B
Q4 2024292$3.15B
Q3 2024280$3.48B
Q2 2024257$3.28B
Q1 2024259$3.09B
Q4 2023245$3.07B
Q3 2023227$2.65B
Q2 2023231$2.61B
Q1 2023197$1.97B
Q4 2022219$2.32B
Q3 2022188$1.15B
Q2 2022174$826.7M
Q1 2022175$787.4M
Q4 2021167$704.2M
Q3 2021171$627.3M
Q2 2021176$1.51B
Q1 2021184$1.31B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Axsome Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding AXSM in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Hennion & Walsh Asset Management, Inc.46,916$5.70M0.21%−2,984−6.0%Reduced
Polygon Management Ltd.46,456$5.64M0.82%+4,925+11.9%Added
TD Asset Management Inc44,192$5.37M0.00%+22,914+107.7%Added
Algert Global LLC44,150$5.36M0.09%+6,720+18.0%Added
Mutual of America Capital Management LLC42,306$5.14M0.05%−997−2.3%Reduced
HB Wealth Management, LLC40,206$4.88M0.03%+15,266+61.2%Added
F/M Investments LLC39,495$4.80M0.18%+7,279+22.6%Added
Pallas Capital Advisors LLC39,444$4.79M0.18%+1,672+4.4%Added
Kennedy Capital Management, Inc.38,774$4.71M0.10%+10,819+38.7%Added
Legal & General Group Plc37,785$4.59M0.00%−2,460−6.1%Reduced
First Trust Advisors LP37,137$4.51M0.00%−25,023−40.3%Reduced
California State Teachers Retirement System34,315$4.17M0.00%+20.0%Added
SVB Capital Management, LLC33,849$4.11M12.95%00.0%Unchanged
Dana Investment Advisors, Inc.33,612$4.08M0.12%+9,539+39.6%Added
New York State Common Retirement Fund33,274$4.04M0.01%+875+2.7%Added
Occam Crest Management LP33,000$4.01M2.72%+33,000New
Group One Trading, L.P.31,703$3.85M0.12%−4,825−13.2%Reduced
Envestnet Asset Management Inc31,342$3.81M0.00%+3,205+11.4%Added
State of Wisconsin Investment Board30,325$3.68M0.01%+4,478+17.3%Added
Capital Fund Management S.A.28,758$3.49M0.03%−32,005−52.7%Reduced
DekaBank Deutsche Girozentrale30,000$3.49M0.01%00.0%Unchanged
Y-Intercept (Hong Kong) Ltd27,027$3.28M0.08%−3,613−11.8%Reduced
LPL Financial LLC26,457$3.21M0.00%+2,211+9.1%Added
Russell Investments Group, Ltd.25,602$3.11M0.00%+7,798+43.8%Added
Jump Financial, LLC25,000$3.04M0.04%−103,500−80.5%Reduced
Alps Advisors Inc24,437$2.97M0.02%−2,095−7.9%Reduced
Ensign Peak Advisors, Inc24,345$2.96M0.00%−6,250−20.4%Reduced
Synovus Financial Corp22,156$2.69M0.03%−170−0.8%Reduced
Meridian Wealth Management, LLC22,124$2.69M0.10%+103+0.5%Added
Lazard Asset Management LLC21,837$2.65M0.00%−7,456−25.5%Reduced
Creative Planning21,278$2.58M0.00%+5,198+32.3%Added
Cubist Systematic Strategies, LLC21,165$2.57M0.04%−138,068−86.7%Reduced
Wealth Enhancement Advisory Services, LLC21,505$2.55M0.00%+827+4.0%Added
Knights of Columbus Asset Advisors LLC20,426$2.48M0.14%+514+2.6%Added
Landscape Capital Management, L.L.C.19,288$2.34M0.15%+13,579+237.9%Added
Dimensional Fund Advisors LP19,192$2.33M0.00%+11,849+161.4%Added
Mirae Asset Global ETFs Holdings Ltd.18,802$2.28M0.00%−3,381−15.2%Reduced
Point72 Asset Management, L.P.18,714$2.27M0.00%−332,259−94.7%Reduced
Edgestream Partners, L.P.18,346$2.23M0.07%−51,615−73.8%Reduced
State of New Jersey Common Pension Fund D18,158$2.21M0.01%+109+0.6%Added
1492 Capital Management LLC18,063$2.19M0.89%+6,220+52.5%Added
Readystate Asset Management LP17,860$2.17M0.11%−76,711−81.1%Reduced
Wolverine Trading, LLC18,157$2.14M0.04%+548+3.1%Added
Stanley-Laman Group, Ltd.17,501$2.13M0.30%+17,501New
Torray LLC17,419$2.12M0.29%+354+2.1%Added
Voleon Capital Management LP16,734$2.03M0.05%+16,734New
Mariner, LLC16,617$2.02M0.00%+1,023+6.6%Added
Intech Investment Management LLC16,049$1.95M0.02%−6,907−30.1%Reduced
SummitTX Capital, L.P.15,350$1.86M0.08%+12,641+466.6%Added
Castleark Management LLC15,143$1.84M0.05%−22,897−60.2%Reduced
Janus Henderson Group PLC15,104$1.83M0.00%+1,104+7.9%Added
Van Eck Associates Corp14,873$1.81M0.00%−1,460−8.9%Reduced
CIBC Private Wealth Group, LLC14,375$1.75M0.00%+686+5.0%Added
Wesbanco Bank Inc13,300$1.62M0.04%00.0%Unchanged
Janney Montgomery Scott LLC13,005$1.58M0.00%−18−0.1%Reduced
Comerica Bank12,758$1.55M0.01%+9,362+275.7%Added
Simplex Trading, LLC12,576$1.53M0.03%−743−5.6%Reduced
Guggenheim Capital LLC12,517$1.52M0.01%+3,065+32.4%Added
Engineers Gate Manager LP12,178$1.48M0.02%−4,478−26.9%Reduced
SG Americas Securities, LLC12,097$1.47M0.01%+5,368+79.8%Added
Oak Ridge Investments LLC12,065$1.47M0.09%−241−2.0%Reduced
STRS Ohio11,900$1.45M0.01%−200−1.7%Reduced
Handelsbanken Fonder AB11,400$1.39M0.00%+600+5.6%Added
Police & Firemen's Retirement System of New Jersey11,202$1.36M0.01%+1,934+20.9%Added
Royal Bank of Canada11,055$1.34M0.00%+3,414+44.7%Added
Quantbot Technologies LP10,877$1.32M0.04%−7,717−41.5%Reduced
Ieq Capital, LLC10,820$1.31M0.00%+2,972+37.9%Added
Erste Asset Management GmbH11,000$1.29M0.01%00.0%Unchanged
Arizona State Retirement System10,196$1.24M0.01%+258+2.6%Added
Resources Investment Advisors, LLC.9,805$1.19M0.01%+496+5.3%Added
Cetera Investment Advisers9,668$1.17M0.00%+2,448+33.9%Added
Trexquant Investment LP9,521$1.16M0.01%+9,521New
HighVista Strategies LLC9,348$1.14M0.28%−1,561−14.3%Reduced
B. Metzler seel. Sohn & Co. AG9,241$1.12M0.01%00.0%Unchanged
State Board of Administration of Florida Retirement System9,064$1.10M0.00%−18−0.2%Reduced
Jain Global LLC9,007$1.09M0.01%+9,007New
KLP Kapitalforvaltning AS9,000$1.09M0.00%−2,200−19.6%Reduced
J. Safra Sarasin Holding AG8,897$1.08M0.02%−10,761−54.7%Reduced
China Universal Asset Management Co., Ltd.8,747$1.06M0.09%−1,142−11.5%Reduced
ProShare Advisors LLC8,698$1.06M0.00%−1,440−14.2%Reduced
Great West Life Assurance Co8,991$1.06M0.00%+1,586+21.4%Added
Inceptionr LLC8,659$1.05M0.25%+8,659New
Teacher Retirement System of Texas8,457$1.03M0.00%−726−7.9%Reduced
J. Goldman & Co LP8,401$1.02M0.04%−31,254−78.8%Reduced
Teachers Retirement System of the State of Kentucky8,328$1.01M0.01%00.0%Unchanged
Two Sigma Investments, LP8,207$996.7K0.00%+8,207New
Captrust Financial Advisors7,959$966.6K0.00%+967+13.8%Added
Cynosure Management, LLC7,844$952.7K0.10%00.0%Unchanged
MONECO Advisors, LLC7,505$911.5K0.08%00.0%Unchanged
Aquatic Capital Management LLC7,426$901.9K0.02%−16,208−68.6%Reduced
Brevan Howard Capital Management LP7,334$890.7K0.01%−7,448−50.4%Reduced
Dark Forest Capital Management LP7,267$882.6K0.03%−9,624−57.0%Reduced
Glenmede Investment Management, LP7,232$878.3K0.00%−1,055−12.7%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)6,989$848.8K0.00%+541+8.4%Added
Great Lakes Advisors, LLC6,676$810.8K0.01%+306+4.8%Added
Capstone Investment Advisors, LLC6,552$795.7K0.01%+6,552New
Advisor Group Holdings, Inc.6,404$773.6K0.00%+3,189+99.2%Added
Perbak Capital Partners LLP6,313$766.7K0.13%+1,585+33.5%Added
D.A. Davidson & Co.6,180$750.6K0.00%−475−7.1%Reduced
Pitcairn Co6,106$741.6K0.06%−2,407−28.3%Reduced