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Axsome Therapeutics, Inc.

AXSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001579428

In the last 90 days, Axsome Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 505 institutions reported holding it in 13F filings for Q2 2026, worth $9.34B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Axsome Therapeutics, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
353
+64 vs. Q4 2024
Shares held
37.5M
+486.2K (+1.3%) vs. Q4 2024
Total value
$4.37B
+$1.24B (+39.7%) vs. Q4 2024
New holders
92
102 more added
Sold out
28
115 more reduced

3 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AXSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 353 institutions
Q1 2021: 184 institutionsQ2 2021: 176 institutionsQ3 2021: 171 institutionsQ4 2021: 167 institutionsQ1 2022: 175 institutionsQ2 2022: 174 institutionsQ3 2022: 188 institutionsQ4 2022: 219 institutionsQ1 2023: 197 institutionsQ2 2023: 231 institutionsQ3 2023: 227 institutionsQ4 2023: 245 institutionsQ1 2024: 259 institutionsQ2 2024: 257 institutionsQ3 2024: 280 institutionsQ4 2024: 292 institutionsQ1 2025: 353 institutionsQ2 2025: 348 institutionsQ3 2025: 355 institutionsQ4 2025: 399 institutionsQ1 2026: 410 institutionsQ2 2026: 505 institutions
Value heldQ1 2025: $4.37B
Q1 2021: $1.31BQ2 2021: $1.51BQ3 2021: $627.3MQ4 2021: $704.2MQ1 2022: $787.4MQ2 2022: $826.7MQ3 2022: $1.15BQ4 2022: $2.32BQ1 2023: $1.97BQ2 2023: $2.61BQ3 2023: $2.65BQ4 2023: $3.07BQ1 2024: $3.09BQ2 2024: $3.28BQ3 2024: $3.48BQ4 2024: $3.15BQ1 2025: $4.37BQ2 2025: $3.95BQ3 2025: $4.51BQ4 2025: $6.86BQ1 2026: $6.41BQ2 2026: $9.34B
Institutions holding AXSM and their total value by quarter
QuarterHoldersValue
Q2 2026505$9.34B
Q1 2026410$6.41B
Q4 2025399$6.86B
Q3 2025355$4.51B
Q2 2025348$3.95B
Q1 2025353$4.37B
Q4 2024292$3.15B
Q3 2024280$3.48B
Q2 2024257$3.28B
Q1 2024259$3.09B
Q4 2023245$3.07B
Q3 2023227$2.65B
Q2 2023231$2.61B
Q1 2023197$1.97B
Q4 2022219$2.32B
Q3 2022188$1.15B
Q2 2022174$826.7M
Q1 2022175$787.4M
Q4 2021167$704.2M
Q3 2021171$627.3M
Q2 2021176$1.51B
Q1 2021184$1.31B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Axsome Therapeutics, Inc.; share changes are against Q4 2024.

Institutions holding AXSM in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Vanguard Group Inc3,876,942$452.2M0.01%−25,537−0.7%Reduced
BlackRock, Inc.3,524,411$411.1M0.01%−8,983−0.3%Reduced
RTW Investments, LP2,922,729$340.9M5.21%−1,128,636−27.9%Reduced
BVF Inc1,690,221$197.1M8.03%+302,157+21.8%Added
FMR LLC1,247,231$145.5M0.01%+246,785+24.7%Added
Macquarie Group Ltd976,260$113.9M0.14%+12,213+1.3%Added
Geode Capital Management, LLC934,853$109.1M0.01%+22,315+2.4%Added
State Street Corp906,020$105.7M0.00%−41,231−4.4%Reduced
Invesco Ltd.857,001$100.0M0.02%+164,537+23.8%Added
Fairmount Funds Management LLC815,176$95.1M14.75%−653,807−44.5%Reduced
Eventide Asset Management, LLC744,850$86.9M1.73%−83,861−10.1%Reduced
Wellington Management Group LLP703,279$82.0M0.02%+30,122+4.5%Added
Alethea Capital Management, LLC667,368$77.8M58.07%−66,949−9.1%Reduced
Assenagon Asset Management S.A.627,418$73.2M0.13%+623,717+16,852.7%Added
PFM Health Sciences, LP556,545$64.9M4.98%+89,118+19.1%Added
D. E. Shaw & Co., Inc.547,665$63.9M0.08%+527,319+2,591.8%Added
Bank of America Corp533,902$62.3M0.01%+329,315+161.0%Added
Man Group plc513,221$59.9M0.18%+349,833+214.1%Added
Morgan Stanley457,416$53.3M0.00%−119,442−20.7%Reduced
Norges Bank437,497$51.0M0.01%+34,471+8.6%Added
Nuveen, LLC413,141$48.2M0.02%+413,141New
Northern Trust Corp410,969$47.9M0.01%+8,469+2.1%Added
OrbiMed Advisors LLC386,700$45.1M1.08%+386,700New
1832 Asset Management L.P.363,200$42.4M0.08%+363,200New
Perceptive Advisors LLC355,107$41.4M1.47%−308,967−46.5%Reduced
Charles Schwab Investment Management Inc337,246$39.3M0.01%+9,212+2.8%Added
Pictet Asset Management Holding SA333,205$38.9M0.04%+328,527+7,022.8%Added
Woodline Partners LP304,084$35.5M0.23%−104,357−25.6%Reduced
Goldman Sachs Group Inc301,718$35.2M0.01%+84,151+38.7%Added
Principal Financial Group Inc295,671$34.5M0.02%+88,606+42.8%Added
UBS Group AG288,647$33.7M0.01%+141,300+95.9%Added
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.285,494$33.3M6.87%+251,775+746.7%Added
Loomis Sayles & Co L P284,170$33.1M0.05%−5,941−2.0%Reduced
Qube Research & Technologies Ltd282,376$32.9M0.05%+126,465+81.1%Added
T. Rowe Price Investment Management, Inc.266,997$31.1M0.02%+266,997New
Cormorant Asset Management, LP250,000$29.2M2.21%−75,000−23.1%Reduced
Voloridge Investment Management, LLC235,383$27.5M0.10%+235,383New
Millennium Management LLC235,311$27.4M0.03%+231,065+5,441.9%Added
Franklin Resources Inc226,515$26.4M0.01%+44,225+24.3%Added
Driehaus Capital Management LLC214,139$25.0M0.24%+214,139New
BNP Paribas Arbitrage, SA182,632$21.3M0.02%−3,029−1.6%Reduced
MetLife Investment Management178,955$20.9M0.11%+156,678+703.3%Added
Cubist Systematic Strategies, LLC177,814$20.7M0.27%+60,877+52.1%Added
Connor, Clark & Lunn Investment Management Ltd.175,942$20.5M0.09%+102,445+139.4%Added
Sofinnova Investments, Inc.175,317$20.4M1.54%−316,409−64.3%Reduced
Raymond James Financial Inc155,075$18.1M0.01%−19,511−11.2%Reduced
Two Sigma Advisers, LP149,600$17.4M0.04%+143,300+2,274.6%Added
Squarepoint Ops LLC141,597$16.5M0.04%+52,167+58.3%Added
Granite Investment Partners, LLC138,719$16.2M0.82%+47,070+51.4%Added
Renaissance Technologies LLC134,400$15.7M0.02%+134,400New
Bank of New York Mellon Corp131,023$15.3M0.00%−3,527−2.6%Reduced
US Bancorp130,295$15.2M0.02%−724−0.6%Reduced
Point72 Asset Management, L.P.126,193$14.7M0.04%−58,945−31.8%Reduced
JPMorgan Chase & Co124,783$14.6M0.00%−77,119−38.2%Reduced
First Turn Management, LLC118,179$13.8M2.78%−73,967−38.5%Reduced
WCM Investment Management, LLC111,948$13.3M0.03%−480.0%Reduced
Rhenman & Partners Asset Management AB109,600$12.8M1.47%−13,000−10.6%Reduced
Iridian Asset Management LLC106,312$12.4M3.89%−18,767−15.0%Reduced
Tri Locum Partners LP101,240$11.8M6.06%−148,529−59.5%Reduced
Affinity Asset Advisors, LLC100,000$11.7M1.83%+25,000+33.3%Added
Voya Investment Management LLC99,000$11.5M0.01%−3,742−3.6%Reduced
Bellevue Group AG96,407$11.2M0.25%−22,523−18.9%Reduced
Deutsche Bank AG94,980$11.1M0.00%−25,567−21.2%Reduced
Jump Financial, LLC92,640$10.8M0.16%+92,640New
Jane Street Group, LLC90,141$10.5M0.02%+11,692+14.9%Added
Spears Abacus Advisors LLC84,264$9.83M0.21%+2,177+2.7%Added
Citadel Advisors LLC83,786$9.77M0.01%−411,603−83.1%Reduced
HSBC Holdings PLC83,572$9.74M0.01%−53,213−38.9%Reduced
Candriam Luxembourg S.C.A.79,930$9.32M0.06%+79,930New
Avidity Partners Management LP77,000$8.98M1.85%−111,000−59.0%Reduced
UBS Asset Management Americas Inc74,892$8.73M0.00%+17,250+29.9%Added
Atika Capital Management LLC73,700$8.60M1.32%+51,700+235.0%Added
Ally Bridge Group (NY) LLC72,113$8.41M7.58%+5,452+8.2%Added
Edgestream Partners, L.P.70,086$8.17M0.28%+70,086New
Marshall Wace, LLP68,696$8.01M0.01%−58,401−45.9%Reduced
Clearbridge Investments, LLC68,164$7.95M0.01%−44,913−39.7%Reduced
IFP Advisors, Inc68,114$7.94M0.24%+275+0.4%Added
Standard Life Aberdeen plc63,954$7.46M0.01%−8,225−11.4%Reduced
Van Eck Associates Corp62,995$7.35M0.01%+62,995New
Moody Aldrich Partners LLC62,339$7.27M1.52%+17,201+38.1%Added
DnB Asset Management AS61,528$7.18M0.03%−12,242−16.6%Reduced
Alliancebernstein L.P.61,471$7.17M0.00%+14,881+31.9%Added
Swiss National Bank61,000$7.11M0.01%−400−0.7%Reduced
Peregrine Capital Management LLC59,721$6.97M0.23%−27,466−31.5%Reduced
Readystate Asset Management LP59,553$6.95M0.35%+59,553New
Hennion & Walsh Asset Management, Inc.59,273$6.91M0.31%+1,437+2.5%Added
AQR Capital Management LLC58,363$6.81M0.01%+20,152+52.7%Added
HB Wealth Management, LLC55,030$6.42M0.05%+55,030New
Rhumbline Advisers54,760$6.39M0.01%+3,515+6.9%Added
Privium Fund Management B.V.52,732$6.15M1.60%−9,500−15.3%Reduced
ExodusPoint Capital Management, LP52,683$6.14M0.08%+52,683New
Blair William & Co52,529$6.13M0.02%−1,853−3.4%Reduced
Barclays PLC51,870$6.05M0.00%−46,118−47.1%Reduced
Susquehanna International Group, LLP51,726$6.03M0.01%+32,956+175.6%Added
PDT Partners, LLC51,199$5.97M0.42%+47,004+1,120.5%Added
Universal- Beteiligungs- und Servicegesellschaft mbH50,096$5.84M0.01%+50,096New
Baldwin Brothers Inc49,570$5.78M0.41%00.0%Unchanged
Lindbrook Capital, LLC48,041$5.60M0.52%−14,103−22.7%Reduced
Adage Capital Partners GP, L.L.C.48,000$5.60M0.01%−12,000−20.0%Reduced
Aquatic Capital Management LLC47,446$5.53M0.14%+46,543+5,154.3%Added