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Axsome Therapeutics, Inc.

AXSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001579428

In the last 90 days, Axsome Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 505 institutions reported holding it in 13F filings for Q2 2026, worth $9.34B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Axsome Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
410
+19 vs. Q4 2025
Shares held
37.9M
+4.97M (+15.1%) vs. Q4 2025
Total value
$6.41B
+$400.1M (+6.7%) vs. Q4 2025
New holders
71
146 more added
Sold out
52
142 more reduced

8 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AXSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 410 institutions
Q1 2021: 184 institutionsQ2 2021: 176 institutionsQ3 2021: 171 institutionsQ4 2021: 167 institutionsQ1 2022: 175 institutionsQ2 2022: 174 institutionsQ3 2022: 188 institutionsQ4 2022: 219 institutionsQ1 2023: 197 institutionsQ2 2023: 231 institutionsQ3 2023: 227 institutionsQ4 2023: 245 institutionsQ1 2024: 259 institutionsQ2 2024: 257 institutionsQ3 2024: 280 institutionsQ4 2024: 292 institutionsQ1 2025: 353 institutionsQ2 2025: 348 institutionsQ3 2025: 355 institutionsQ4 2025: 399 institutionsQ1 2026: 410 institutionsQ2 2026: 505 institutions
Value heldQ1 2026: $6.41B
Q1 2021: $1.31BQ2 2021: $1.51BQ3 2021: $627.3MQ4 2021: $704.2MQ1 2022: $787.4MQ2 2022: $826.7MQ3 2022: $1.15BQ4 2022: $2.32BQ1 2023: $1.97BQ2 2023: $2.61BQ3 2023: $2.65BQ4 2023: $3.07BQ1 2024: $3.09BQ2 2024: $3.28BQ3 2024: $3.48BQ4 2024: $3.15BQ1 2025: $4.37BQ2 2025: $3.95BQ3 2025: $4.51BQ4 2025: $6.86BQ1 2026: $6.41BQ2 2026: $9.34B
Institutions holding AXSM and their total value by quarter
QuarterHoldersValue
Q2 2026505$9.34B
Q1 2026410$6.41B
Q4 2025399$6.86B
Q3 2025355$4.51B
Q2 2025348$3.95B
Q1 2025353$4.37B
Q4 2024292$3.15B
Q3 2024280$3.48B
Q2 2024257$3.28B
Q1 2024259$3.09B
Q4 2023245$3.07B
Q3 2023227$2.65B
Q2 2023231$2.61B
Q1 2023197$1.97B
Q4 2022219$2.32B
Q3 2022188$1.15B
Q2 2022174$826.7M
Q1 2022175$787.4M
Q4 2021167$704.2M
Q3 2021171$627.3M
Q2 2021176$1.51B
Q1 2021184$1.31B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Axsome Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding AXSM in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock, Inc.3,912,844$661.3M0.01%−6990.0%Reduced
Vanguard Portfolio Management LLC2,058,170$347.9M0.02%+2,058,170New
Vanguard Capital Management LLC1,937,752$327.5M0.01%+1,937,752New
FMR LLC1,566,995$264.9M0.01%+385,373+32.6%Added
Price T Rowe Associates Inc1,317,059$222.6M0.03%−192,811−12.8%Reduced
Invesco Ltd.1,297,678$219.3M0.02%+24,184+1.9%Added
Geode Capital Management, LLC1,162,981$196.6M0.01%+152,732+15.1%Added
Wellington Management Group LLP1,145,306$193.6M0.04%−76,350−6.2%Reduced
Deep Track Capital, LP1,100,000$185.9M3.84%−50,000−4.3%Reduced
State Street Corp986,809$166.8M0.01%+28,659+3.0%Added
Assenagon Asset Management S.A.865,958$146.4M0.23%+397,976+85.0%Added
Nomura Asset Management International Inc.812,809$137.4M0.24%−176,638−17.9%Reduced
Adage Capital Partners GP, L.L.C.737,578$124.7M0.19%+370,000+100.7%Added
Alethea Capital Management, LLC649,114$109.7M58.94%−19,596−2.9%Reduced
D. E. Shaw & Co., Inc.603,465$102.0M0.08%+54,352+9.9%Added
Bank of America Corp598,091$101.1M0.01%−19,942−3.2%Reduced
First Trust Advisors LP577,479$97.6M0.07%+534,066+1,230.2%Added
UBS Group AG547,195$92.5M0.02%+191,877+54.0%Added
Eventide Asset Management, LLC519,558$87.8M1.45%−51,668−9.0%Reduced
Morgan Stanley476,701$80.6M0.00%−14,500−3.0%Reduced
Franklin Resources Inc438,490$74.1M0.02%+95,917+28.0%Added
Point72 Asset Management, L.P.424,750$71.8M0.12%+406,751+2,259.9%Added
Goldman Sachs Group Inc421,447$71.2M0.01%+120,541+40.1%Added
Pictet Asset Management Holding SA415,983$70.3M0.07%−20,080−4.6%Reduced
Northern Trust Corp401,459$67.9M0.01%+11,028+2.8%Added
Charles Schwab Investment Management Inc395,118$66.8M0.01%−7,582−1.9%Reduced
Hood River Capital Management LLC371,503$62.8M0.63%+5,327+1.5%Added
Principal Financial Group Inc350,488$59.2M0.03%−12,626−3.5%Reduced
Nuveen, LLC335,737$56.7M0.02%−13,472−3.9%Reduced
Qube Research & Technologies Ltd335,334$56.7M0.08%+9,894+3.0%Added
Two Sigma Investments, LP322,778$54.6M0.05%+177,181+121.7%Added
Vanguard Fiduciary Trust Co295,139$49.9M0.01%+295,139New
Driehaus Capital Management LLC292,370$49.4M0.36%+71,852+32.6%Added
Citadel Advisors LLC281,503$47.6M0.03%+143,290+103.7%Added
PFM Health Sciences, LP264,304$44.7M4.70%+12,742+5.1%Added
Loomis Sayles & Co L P256,625$43.4M0.06%−58,766−18.6%Reduced
JPMorgan Chase & Co270,160$43.4M0.00%+36,969+15.9%Added
OrbiMed Advisors LLC213,921$36.2M0.82%−39,200−15.5%Reduced
Sofinnova Investments, Inc.212,747$36.0M1.80%+200,481+1,634.4%Added
Bank of New York Mellon Corp206,644$34.9M0.01%−48,453−19.0%Reduced
Frontier Capital Management Co LLC203,066$34.3M0.35%+45,375+28.8%Added
First Turn Management, LLC188,772$31.9M3.56%−18,149−8.8%Reduced
BNP Paribas Arbitrage, SA188,146$31.8M0.02%−116,242−38.2%Reduced
Citigroup Inc185,658$31.4M0.02%−18,446−9.0%Reduced
Voya Investment Management LLC183,967$31.1M0.03%+10,666+6.2%Added
Ameriprise Financial Inc176,314$29.8M0.01%+76,398+76.5%Added
Renaissance Technologies LLC164,300$27.8M0.04%−5,700−3.4%Reduced
Woodline Partners LP162,221$27.4M0.10%+11,357+7.5%Added
MetLife Investment Management152,645$25.8M0.13%−12,226−7.4%Reduced
Perceptive Advisors LLC149,950$25.3M0.50%+1,050+0.7%Added
Standard Life Aberdeen plc149,688$25.3M0.04%+52,275+53.7%Added
Voleon Capital Management LP147,867$25.0M0.54%+37,688+34.2%Added
Raymond James Financial Inc147,766$24.3M0.01%−2,332−1.6%Reduced
1832 Asset Management L.P.143,800$24.3M0.03%+130,100+949.6%Added
Man Group plc142,271$24.0M0.05%−86,370−37.8%Reduced
Marshall Wace, LLP141,236$23.9M0.03%−179,332−55.9%Reduced
Algert Global LLC135,460$22.9M0.34%−13,932−9.3%Reduced
Connor, Clark & Lunn Investment Management Ltd.134,792$22.8M0.05%−53,466−28.4%Reduced
US Bancorp131,414$22.2M0.03%+429+0.3%Added
Manufacturers Life Insurance Company, The117,093$19.8M0.02%−16,791−12.5%Reduced
Squarepoint Ops LLC114,102$19.3M0.04%−40,898−26.4%Reduced
Federated Hermes, Inc.108,571$18.4M0.03%+21,291+24.4%Added
Emerald Advisers, LLC107,610$18.2M0.58%−472−0.4%Reduced
Deutsche Bank AG104,266$17.6M0.01%+6,009+6.1%Added
AQR Capital Management LLC104,059$17.6M0.01%+641+0.6%Added
WCM Investment Management, LLC107,817$17.3M0.04%−4,241−3.8%Reduced
Healthcare of Ontario Pension Plan Trust Fund97,550$16.5M0.03%+97,550New
UBS Asset Management Americas Inc94,937$16.0M0.00%+7,688+8.8%Added
Royce & Associates LP94,017$15.9M0.16%00.0%Unchanged
Canada Pension Plan Investment Board91,400$15.4M0.01%−11,800−11.4%Reduced
M&G Plc91,339$15.4M0.08%+1,011+1.1%Added
DnB Asset Management AS90,088$15.2M0.05%−11,014−10.9%Reduced
Spears Abacus Advisors LLC84,154$14.2M0.28%00.0%Unchanged
Nicholas Investment Partners, LP81,478$13.8M0.99%−10,086−11.0%Reduced
Granite Investment Partners, LLC80,299$13.6M0.83%−4,595−5.4%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH70,725$12.0M0.02%+1,867+2.7%Added
SEI Investments Co70,064$11.8M0.01%+22,464+47.2%Added
Swiss National Bank69,100$11.7M0.01%+200+0.3%Added
HSBC Holdings PLC68,453$11.6M0.01%+68,453New
Alliancebernstein L.P.62,822$11.5M0.00%+9,682+18.2%Added
Iridian Asset Management LLC67,491$11.4M4.62%−6,292−8.5%Reduced
Emerald Mutual Fund Advisers Trust67,054$11.3M0.55%−554−0.8%Reduced
Summit Financial, LLC65,249$11.0M0.14%−5,379−7.6%Reduced
Rhenman & Partners Asset Management AB63,800$10.8M1.33%−51,000−44.4%Reduced
Tri Locum Partners LP62,116$10.5M1.47%−139,511−69.2%Reduced
Wells Fargo & Company61,405$10.4M0.00%−28,256−31.5%Reduced
IFP Advisors, Inc60,994$10.3M0.21%−1,454−2.3%Reduced
Neuberger Berman Group LLC60,759$10.3M0.01%−8,724−12.6%Reduced
Privium Fund Management B.V.58,729$9.93M2.07%+1,851+3.3%Added
Bridgewater Associates, LP56,951$9.63M0.04%+9,507+20.0%Added
HighTower Advisors, LLC56,633$9.57M0.01%+661+1.2%Added
Axiom Investors LLC56,529$9.55M0.11%−6,861−10.8%Reduced
Hillsdale Investment Management Inc.53,363$9.02M0.25%+53,363New
Rhumbline Advisers51,619$8.72M0.01%−614−1.2%Reduced
California Public Employees Retirement System50,879$8.60M0.01%+50,879New
HB Wealth Management, LLC50,237$8.49M0.06%+16,135+47.3%Added
New York State Common Retirement Fund50,113$8.47M0.01%+7,604+17.9%Added
Cormorant Asset Management, LP50,000$8.45M0.43%−25,000−33.3%Reduced
Peregrine Capital Management LLC47,296$7.99M0.30%+663+1.4%Added
Susquehanna International Group, LLP47,198$7.98M0.01%+17,357+58.2%Added