Axsome Therapeutics, Inc.
AXSM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001579428
In the last 90 days, Axsome Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 505 institutions reported holding it in 13F filings for Q2 2026, worth $9.34B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Axsome Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 399
- +53 vs. Q3 2025
- Shares held
- 37.6M
- +542.0K (+1.5%) vs. Q3 2025
- Total value
- $6.86B
- +$2.36B (+52.3%) vs. Q3 2025
- New holders
- 87
- 139 more added
- Sold out
- 34
- 122 more reduced
9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AXSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 505 | $9.34B |
| Q1 2026 | 410 | $6.41B |
| Q4 2025 | 399 | $6.86B |
| Q3 2025 | 355 | $4.51B |
| Q2 2025 | 348 | $3.95B |
| Q1 2025 | 353 | $4.37B |
| Q4 2024 | 292 | $3.15B |
| Q3 2024 | 280 | $3.48B |
| Q2 2024 | 257 | $3.28B |
| Q1 2024 | 259 | $3.09B |
| Q4 2023 | 245 | $3.07B |
| Q3 2023 | 227 | $2.65B |
| Q2 2023 | 231 | $2.61B |
| Q1 2023 | 197 | $1.97B |
| Q4 2022 | 219 | $2.32B |
| Q3 2022 | 188 | $1.15B |
| Q2 2022 | 174 | $826.7M |
| Q1 2022 | 175 | $787.4M |
| Q4 2021 | 167 | $704.2M |
| Q3 2021 | 171 | $627.3M |
| Q2 2021 | 176 | $1.51B |
| Q1 2021 | 184 | $1.31B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Axsome Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vanguard Group Inc | 4,164,818 | $760.7M | 0.01% | −15,828−0.4% | Reduced |
| BlackRock, Inc. | 3,913,543 | $714.8M | 0.01% | +122,614+3.2% | Added |
| Price T Rowe Associates Inc | 1,509,870 | $275.8M | 0.03% | +472,422+45.5% | Added |
| Invesco Ltd. | 1,273,494 | $232.6M | 0.02% | +282,937+28.6% | Added |
| Wellington Management Group LLP | 1,221,656 | $223.1M | 0.04% | −112,904−8.5% | Reduced |
| FMR LLC | 1,181,622 | $215.8M | 0.01% | +253,739+27.3% | Added |
| Deep Track Capital, LP | 1,150,000 | $210.0M | 4.79% | +250,000+27.8% | Added |
| Geode Capital Management, LLC | 1,010,249 | $184.5M | 0.01% | +12,549+1.3% | Added |
| Nomura Asset Management International Inc. | 989,447 | $180.7M | 0.27% | +989,447 | New |
| State Street Corp | 958,150 | $175.0M | 0.01% | +15,190+1.6% | Added |
| RTW Investments, LP | 888,001 | $162.2M | 1.62% | −230,882−20.6% | Reduced |
| Alethea Capital Management, LLC | 668,710 | $122.1M | 59.30% | −2,173−0.3% | Reduced |
| Bank of America Corp | 618,033 | $112.9M | 0.01% | +256,772+71.1% | Added |
| Eventide Asset Management, LLC | 571,226 | $104.2M | 1.63% | −175,172−23.5% | Reduced |
| D. E. Shaw & Co., Inc. | 549,113 | $100.3M | 0.08% | +252,826+85.3% | Added |
| Norges Bank | 495,456 | $90.5M | 0.01% | +495,456 | New |
| Morgan Stanley | 491,201 | $89.7M | 0.01% | +81,621+19.9% | Added |
| Assenagon Asset Management S.A. | 467,982 | $85.5M | 0.13% | +173,211+58.8% | Added |
| Pictet Asset Management Holding SA | 436,063 | $79.6M | 0.08% | +73,925+20.4% | Added |
| Charles Schwab Investment Management Inc | 402,700 | $73.5M | 0.01% | +20,653+5.4% | Added |
| Northern Trust Corp | 390,431 | $71.3M | 0.01% | −19,104−4.7% | Reduced |
| Adage Capital Partners GP, L.L.C. | 367,578 | $67.1M | 0.10% | −77,422−17.4% | Reduced |
| Hood River Capital Management LLC | 366,176 | $66.9M | 0.73% | +6,219+1.7% | Added |
| Principal Financial Group Inc | 363,114 | $66.3M | 0.03% | −5,320−1.4% | Reduced |
| UBS Group AG | 355,318 | $64.9M | 0.01% | +142,867+67.2% | Added |
| Nuveen, LLC | 349,209 | $63.8M | 0.02% | +50,868+17.1% | Added |
| Franklin Resources Inc | 342,573 | $62.6M | 0.02% | +56,975+19.9% | Added |
| Qube Research & Technologies Ltd | 325,440 | $59.4M | 0.09% | −186−0.1% | Reduced |
| Marshall Wace, LLP | 320,568 | $58.5M | 0.06% | −57,456−15.2% | Reduced |
| Loomis Sayles & Co L P | 315,391 | $57.6M | 0.07% | −14,734−4.5% | Reduced |
| BNP Paribas Arbitrage, SA | 304,388 | $55.6M | 0.04% | +114,282+60.1% | Added |
| Goldman Sachs Group Inc | 300,906 | $55.0M | 0.01% | +76,767+34.2% | Added |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 278,835 | $50.9M | 4.52% | −47,483−14.6% | Reduced |
| Bank of New York Mellon Corp | 255,097 | $46.6M | 0.01% | +1,834+0.7% | Added |
| OrbiMed Advisors LLC | 253,121 | $46.2M | 0.95% | −278,679−52.4% | Reduced |
| PFM Health Sciences, LP | 251,562 | $45.9M | 4.65% | −278,770−52.6% | Reduced |
| JPMorgan Chase & Co | 233,191 | $42.6M | 0.00% | −17,322−6.9% | Reduced |
| Man Group plc | 228,641 | $41.8M | 0.08% | −59,267−20.6% | Reduced |
| Driehaus Capital Management LLC | 220,518 | $40.3M | 0.27% | −2,890−1.3% | Reduced |
| Vestal Point Capital, LP | 210,000 | $38.4M | 1.41% | +60,000+40.0% | Added |
| First Turn Management, LLC | 206,921 | $37.8M | 4.32% | +54,307+35.6% | Added |
| Citigroup Inc | 204,104 | $37.3M | 0.03% | +62,091+43.7% | Added |
| Tri Locum Partners LP | 201,627 | $36.8M | 4.78% | −90,510−31.0% | Reduced |
| Two Sigma Advisers, LP | 188,500 | $34.4M | 0.07% | +188,500 | New |
| Connor, Clark & Lunn Investment Management Ltd. | 188,258 | $34.4M | 0.09% | −20,811−10.0% | Reduced |
| Voya Investment Management LLC | 173,301 | $31.7M | 0.03% | +59,251+52.0% | Added |
| Renaissance Technologies LLC | 170,000 | $31.0M | 0.05% | +20,000+13.3% | Added |
| MetLife Investment Management | 164,871 | $30.1M | 0.15% | −32,447−16.4% | Reduced |
| Frontier Capital Management Co LLC | 157,691 | $28.8M | 0.31% | +31,309+24.8% | Added |
| Squarepoint Ops LLC | 155,000 | $28.3M | 0.06% | 00.0% | Unchanged |
| Woodline Partners LP | 150,864 | $27.6M | 0.11% | −181,000−54.5% | Reduced |
| Algert Global LLC | 149,392 | $27.3M | 0.43% | +105,242+238.4% | Added |
| Perceptive Advisors LLC | 148,900 | $27.2M | 0.50% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 145,597 | $26.6M | 0.04% | +137,390+1,674.1% | Added |
| Citadel Advisors LLC | 138,213 | $25.2M | 0.02% | −20,193−12.7% | Reduced |
| Jane Street Group, LLC | 137,283 | $25.1M | 0.03% | +6,438+4.9% | Added |
| Raymond James Financial Inc | 150,098 | $24.8M | 0.01% | −8,591−5.4% | Reduced |
| US Bancorp | 130,985 | $23.9M | 0.03% | −548−0.4% | Reduced |
| Manufacturers Life Insurance Company, The | 133,884 | $23.7M | 0.02% | +1,167+0.9% | Added |
| Rhenman & Partners Asset Management AB | 114,800 | $21.0M | 1.96% | −58,000−33.6% | Reduced |
| Voleon Capital Management LP | 110,179 | $20.1M | 0.43% | +93,445+558.4% | Added |
| Emerald Advisers, LLC | 108,082 | $19.7M | 0.61% | −860−0.8% | Reduced |
| AQR Capital Management LLC | 103,418 | $18.9M | 0.01% | −15,238−12.8% | Reduced |
| Canada Pension Plan Investment Board | 103,200 | $18.8M | 0.01% | +38,800+60.2% | Added |
| DnB Asset Management AS | 101,102 | $18.5M | 0.06% | −879−0.9% | Reduced |
| Ameriprise Financial Inc | 99,916 | $18.2M | 0.00% | −8,320−7.7% | Reduced |
| Deutsche Bank AG | 98,257 | $17.9M | 0.01% | +1,565+1.6% | Added |
| Standard Life Aberdeen plc | 97,413 | $17.8M | 0.03% | +2,765+2.9% | Added |
| Royce & Associates LP | 94,017 | $17.2M | 0.17% | +37,981+67.8% | Added |
| Nicholas Investment Partners, LP | 91,564 | $16.7M | 1.22% | +42,907+88.2% | Added |
| WCM Investment Management, LLC | 112,058 | $16.7M | 0.03% | −7,638−6.4% | Reduced |
| M&G Plc | 90,328 | $16.5M | 0.08% | +90,328 | New |
| Wells Fargo & Company | 89,661 | $16.4M | 0.00% | +34,388+62.2% | Added |
| Federated Hermes, Inc. | 87,280 | $15.9M | 0.03% | +29,995+52.4% | Added |
| UBS Asset Management Americas Inc | 87,249 | $15.9M | 0.00% | +558+0.6% | Added |
| Granite Investment Partners, LLC | 84,894 | $15.5M | 0.92% | −3,664−4.1% | Reduced |
| Spears Abacus Advisors LLC | 84,154 | $15.4M | 0.29% | +30.0% | Added |
| Barclays PLC | 76,853 | $14.0M | 0.01% | +4,786+6.6% | Added |
| Cormorant Asset Management, LP | 75,000 | $13.7M | 0.78% | −25,000−25.0% | Reduced |
| Iridian Asset Management LLC | 73,783 | $13.5M | 4.96% | −9,770−11.7% | Reduced |
| Summit Financial, LLC | 70,628 | $12.9M | 0.19% | −6,912−8.9% | Reduced |
| Neuberger Berman Group LLC | 69,483 | $12.7M | 0.01% | −21,695−23.8% | Reduced |
| Swiss National Bank | 68,900 | $12.6M | 0.01% | +2,100+3.1% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 68,858 | $12.6M | 0.02% | +956+1.4% | Added |
| Emerald Mutual Fund Advisers Trust | 67,608 | $12.3M | 0.60% | +2,103+3.2% | Added |
| Axiom Investors LLC | 63,390 | $11.6M | 0.10% | +14,137+28.7% | Added |
| IFP Advisors, Inc | 62,448 | $11.4M | 0.26% | −865−1.4% | Reduced |
| Walleye Capital LLC | 60,100 | $11.0M | 0.06% | +59,600+11,920.0% | Added |
| Privium Fund Management B.V. | 56,878 | $10.4M | 1.91% | +4,146+7.9% | Added |
| Edgestream Partners, L.P. | 56,364 | $10.3M | 0.29% | +38,018+207.2% | Added |
| HighTower Advisors, LLC | 55,972 | $10.2M | 0.01% | −1,143−2.0% | Reduced |
| Atika Capital Management LLC | 55,500 | $10.1M | 1.41% | +6,500+13.3% | Added |
| Alliancebernstein L.P. | 53,140 | $9.71M | 0.00% | −9,925−15.7% | Reduced |
| Rhumbline Advisers | 52,233 | $9.54M | 0.01% | −8,545−14.1% | Reduced |
| Trexquant Investment LP | 49,136 | $8.97M | 0.08% | +39,615+416.1% | Added |
| Baldwin Brothers Inc | 48,570 | $8.87M | 0.57% | 00.0% | Unchanged |
| SEI Investments Co | 47,600 | $8.69M | 0.01% | −527−1.1% | Reduced |
| Bridgewater Associates, LP | 47,444 | $8.67M | 0.03% | +47,444 | New |
| Blair William & Co | 46,840 | $8.55M | 0.02% | −3,237−6.5% | Reduced |
| Peregrine Capital Management LLC | 46,633 | $8.52M | 0.26% | −17,888−27.7% | Reduced |